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Hamid, Hamada; Devinsky, Orrin; Vickrey, Barbara G; Berg, Anne T; Bazil, Carl W; Langfitt, John T; Walczak, Thaddeus S; Sperling, Michael R; Shinnar, Shlomo; Spencer, Susan S
"Suicide outcomes after resective epilepsy surgery"
Epilepsy & behavior 2011 Mar; 20(3):462-464
People with epilepsy have a higher risk for suicide than people without epilepsy. The relationship between seizure control and suicide is controversial. A standardized protocol to record history, diagnostic testing, and neuropsychiatric assessments was administered. The Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) were administered presurgically and yearly for up to 5 years. Among the 396 enrolled, 4 of 27 deaths were attributed to suicide. The standardized mortality ratio, compared with suicides in the U.S. population and adjusted for age and gender, was 13.3 (95% CI=3.6-34.0). Only one patient had a BDI score suggestive of severe depression (BDI=33), one had depressive symptoms that did not the meet the depressive range (BDI=7), and the other two reported no depressive symptoms. Two of the patients reported moderate to severe anxiety symptoms (BAI=17 and 21, respectively). Suicide may occur after epilepsy surgery, even when patients report excellent seizure control

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