Citation from the publications of

Vazquez B; Devinksy O; Luciano D; Alper K; et al
"Juvenile myoclonic epilepsy: Clinical features and factors related to misdiagnosis"
Journal of epilepsy 1993 ; 6(4):233-238
Identified 37 patients (aged 11-57 yrs) with juvenile myoclonic epilepsy (JME) out of 740 consecutive epilepsy patients. Only 3 were initially diagnosed with JME. Factors leading to misdiagnosis included warnings (auras) suggesting partial seizures before generalized tonic-clonic seizures (GTCS), confusion between absence and complex partial seizures, failure of patients to spontaneously report or for physicians to obtain a history of myoclonic jerks, and failure to report myoclonic jerks to medical personnel despite specific questioning. Psychiatric disorders were common: depression occurred in 9 Ss and panic disorder in 7 Ss. Following diagnosis, 86% of Ss were seizure-free on antiepileptic drugs. To improve diagnostic sensitivity, Ss with epilepsy should be routinely questioned about the occurrence of myoclonic seizures, and JME should not be excluded because patients report nonspecific warnings before GTCS.

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