Pseudolymphoma evolving into diffuse large B-cell lymphoma [Case Report]
Anandasabapathy, Niroshana; Pulitzer, Melissa; Epstein, Wendy; Rosenman, Karla; Latkowski, Jo-Ann
A 46-year-old man presented with a 1-year history of asymptomatic papules on the right arm, without an antecedent event. Initial clinical and histopathologic features were consistent with a pseudolymphoma without gene rearrangements, and the patient was treated with intralesional glucocorticoids. Four months later, the patient developed additional papules and plaques on the right arm, and, at this time, clinical and histopathologic features were most consistent with a T-cell-rich, large B-cell lymphoma, with monoclonal immunoglobulin light chain gene rearrangement. Systemic evaluation showed no evidence of extracutaneous involvement. The transformation of a pseudolymphoma into a large B-cell lymphoma is a rare event. This patient's subtype, diffuse large B-cell lymphoma-other, carries an intermediate prognosis when compared to the more aggressive leg subtype and more indolent folliculocentric subtype. Potential therapeutic options include local radiotherapy, chemotherapy, and rituximab
PMID: 18627758
ISSN: 1087-2108
CID: 81356
Acne vulgaris and hidradenitis suppurativa
Chapter by: Epstein W
in: Current dermatologic diagnosis & treatment by Freedberg IM; Sanchez MR [Eds]
Philadelphia : Lippincott Williams & Wilkins, 2001
pp. 4-5
ISBN: 0781735319
CID: 3667