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SILDENAFIL CITRATE INDUCED RETINAL TOXICITY-ELECTRORETINOGRAM, OPTICAL COHERENCE TOMOGRAPHY, AND ADAPTIVE OPTICS FINDINGS

Yanoga, Fatoumata; Gentile, Ronald C; Chui, Toco Y P; Freund, K Bailey; Fell, Millie; Dolz-Marco, Rosa; Rosen, Richard B
BACKGROUND/PURPOSE/OBJECTIVE:To report a case of persistent retinal toxicity associated with a high dose of sildenafil citrate intake. METHODS:Single retrospective case report. RESULTS:A 31-year-old white man with no medical history presented with complaints of bilateral multicolored photopsias and erythropsia (red-tinted vision), shortly after taking sildenafil citrate-purchased through the internet. Patient was found to have cone photoreceptor damage, demonstrated using electroretinogram, optical coherence tomography, and adaptive optics imaging. The patient's symptoms and the photoreceptor structural changes persisted for several months. CONCLUSION/CONCLUSIONS:Sildenafil citrate is a widely used erectile dysfunction medication that is typically associated with transient visual symptoms in normal dosage. At high dosage, sildenafil citrate can lead to persistent retinal toxicity in certain individuals.
PMCID:6110976
PMID: 29489563
ISSN: 1937-1578
CID: 2965922

Presumed pyogenic granuloma associated with intravitreal anti-vascular endothelial growth factor therapy

Jung, Jesse J; Della Torre, Kara E; Fell, Millie R; Teng, Christopher C; K Bailey, Freund
To report a case of a presumed pyogenic granuloma at the site of multiple intravitreal anti-Vascular Endothelial Growth Factor (VEGF) injections. Intravitreal anti-VEGF injections can be complicated by a localized reaction of the conjunctiva
PMCID:3249641
PMID: 22216076
ISSN: 1874-3641
CID: 148738