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Rule Out Acute Kidney Injury in the Emergency Department With a Urinary Dipstick

Stevens, Jacob S; Xu, Katherine; Corker, Alexa; Gopal, Tejashree S; Sayan, Osman R; Geraghty, Erin P; Yaeh, Andrew M; Kosuri, Yaagnik D; Burton, John R; Lincoln, Saul V; Callahan, Miriam P; Breheney, Rebecca K; Beenken, Andrew S; Gamino, Juliana N; Felman, Ariel E; Gehani, Anjali; Giordano, Hayley A; Gozali, Aileen; Guerrero Herrera, Eddie F; Hatcher, Britney A; Kheir, Lena A; Li, Yuanji; Mitsui, Erika K; Nha, Jae I; Sayan, Alexander T; Spaiser, Samuel J; Arumugam, Siddarth; Sia, Samuel K; King, Kristen L; Mohan, Sumit; Barasch, Jonathan
Introduction/UNASSIGNED:The identification of acute injury of the kidney relies on serum creatinine (SCr), a functional marker with poor temporal resolution as well as limited sensitivity and specificity for cellular injury. In contrast, urinary biomarkers of kidney injury have the potential to detect cellular stress and damage in real time. Methods/UNASSIGNED: = 426) entering an emergency department in New York City and subsequently admitted for inpatient care. Results/UNASSIGNED: < 0.001). Conclusion/UNASSIGNED:We show that the introduction of a bedside uNGAL dipstick permits accurate triage by identifying individuals who do not have tubular injury. In an era of shortening length of stay and rapid decisions based on isolated SCr measurements, real-time exclusion of kidney injury by a dipstick will be particularly useful to overcome the retrospective, insensitive, and nonspecific attributes of SCr.
PMCID:7609964
PMID: 33163719
ISSN: 2468-0249
CID: 4851512