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Longitudinal data support university-based biomedical entrepreneurship education programs

Vizgan, Gabriel; Hill-Whilton, Zachary; Achuonjei, Joy; Schweickart, Tucker; Chitale, Sadhana; Gillespie, Colleen; Gold-von Simson, Gabrielle
PMID: 36922690
ISSN: 1546-1696
CID: 5443502

The Biomedical Entrepreneurship Skills Development Program for the Advancement of Research Translation: Foundations of Biomedical Startups course, metrics, and impact

Schweickart, Tucker; Hill-Whilton, Zachary; Chitale, Sadhana; Cobos, Daniel; Gilon-Yanai, Michal; Achuonjei, Joy; Vizgan, Gabriel; Gillespie, Colleen; Gold-Von Simson, Gabrielle
Background/Objective: A growing number of biomedical doctoral graduates are entering the biotechnology and industry workforce, though most lack training in business practice. Entrepreneurs can benefit from venture creation and commercialization training that is largely absent from standard biomedical educational curricula. The NYU Biomedical Entrepreneurship Educational Program (BEEP) seeks to fill this training gap to prepare and motivate biomedical entrepreneurs to develop an entrepreneurial skill set, thus accelerating the pace of innovation in technology and business ventures. Methods: The NYU BEEP Model was developed and implemented with funding from NIDDK and NCATS. The program consists of a core introductory course, topic-based interdisciplinary workshops, venture challenges, on-line modules, and mentorship from experts. Here, we evaluate the efficacy of the core, introductory course, Foundations of Biomedical Startups, through the use of pre/post-course surveys and free-response answers. Results: After 2 years, 153 participants (26% doctoral students, 23% post-doctoral PhDs, 20% faculty, 16% research staff, 15% other) have completed the course. Evaluation data show self-assessed knowledge gain in all domains. The percentage of students rating themselves as either competent or on the way to being an expert in all areas was significantly higher post-course (P < 0.05). In each content area, the percentages of participants rating themselves as very interested increased post-course. 95% of those surveyed reported the course met its objectives, and 95% reported a higher likelihood of pursuing commercialization of discoveries post-course. Conclusion: NYU BEEP can serve as a model to develop similar curricula/programs to enhance entrepreneurial activity of early-stage researchers.
SCOPUS:85149914512
ISSN: 2059-8661
CID: 5446842

The development of a clinical research educational training for community health workers using the joint task force for clinical trial competency framework

Yakubov, Amin; Pimenova, Dina; Ahmed, Alzahraa; Corvacho, Romelia; Madigan, Joanna; Naik, Jay; Lyu, Chen; McFarlane, Anita; Foster, Victoria; Haseltine, Megan; Trifonov, Alexandr; Cabrera, Ivette; Rios, Clarissa; Gross, Rachel; Jay, Melanie; Lord, Aaron; Gold-von Simson, Gabrielle; Roy, Brita; Freeman, Amy; Islam, Nadia; Holahan, James
PMCID:10733486
PMID: 38130403
ISSN: 1663-9812
CID: 5612162

Dancing with uncertainties in the era of artificial intelligence [Editorial]

Ventura, Juan; Gold-von Simson, Gabrielle; Sukhov, Renat
In this commentary, a medical student reflects on the promise of artificial intelligence (AI) in mitigation of physician burnout and moral injury. The rapid introduction of AI technologies may present a challenge to medical professionals, especially those engaged in the transdisciplinary care of children with disabilities.
PMCID:10578284
PMID: 37718876
ISSN: 1875-8894
CID: 5602742

Integrating medicine, engineering and business to educate early-stage researchers in cardiovascular device development

Vizgan, Gabriel; Hill-Whilton, Zachary; Gillespie, Colleen; Cobos, Daniel; Johnson, LeAnn; Dib, Nabil; Gold-von Simson, Gabrielle
PMID: 36207597
ISSN: 1546-1696
CID: 5339902

Chronic Non-infectious Osteomyelitis Mimicking Scurvy as the Presenting Sign of Crohn's Disease: Case Report [Case Report]

Goldfarb, Alexa; Breitling, Stefan; Amadasun, Owen; Kiernan, Bridget; Gold-von Simson, Gabrielle; Sagalowsky, Selin T
Chronic non-infectious osteomyelitis (CNO) is a rare, inflammatory process associated with pediatric inflammatory bowel disease (IBD). Signs and symptoms of CNO parallel scurvy, a nutritional deficiency that can affect children with autism spectrum disorder (ASD). This is the first report of a child initially thought to have scurvy, then subsequently diagnosed with CNO as the presenting manifestation of Crohn's disease. This case enhances the literature elucidating extra-intestinal manifestations of IBD and pediatric nutritional deficiencies.
PMCID:9043343
PMID: 35498788
ISSN: 2296-2360
CID: 5203372

Characteristics of Hospitalized Children With SARS-CoV-2 in the New York City Metropolitan Area

Verma, Sourabh; Lumba, Rishi; Dapul, Heda M; Simson, Gabrielle Gold-von; Phoon, Colin K; Phil, M; Lighter, Jennifer L; Farkas, Jonathan S; Vinci, Alexandra; Noor, Asif; Raabe, Vanessa N; Rhee, David; Rigaud, Mona; Mally, Pradeep V; Randis, Tara M; Dreyer, Benard; Ratner, Adam J; Manno, Catherine S; Chopra, Arun
PMID: 33033078
ISSN: 2154-1671
CID: 4627202

Factors Associated With Parental Participation in Family-Centered Rounds

Glick, Alexander F; Goonan, Michael; Kim, Chan; Sandmeyer, Diana; Londoño, Kevin; Gold-von Simson, Gabrielle
OBJECTIVES/OBJECTIVE:Although families positively perceive family-centered rounds (FCR), factors associated with engagement have been examined in few studies. Our objective for this study was to test the hypothesis that inviting the parent to speak and nurse presence are associated with parent engagement during FCR. METHODS:= 199) of inpatients on the pediatric hospital medicine service at an academic medical center. We used a standardized checklist to record outcomes of engagement (number of questions asked and participation occurrences), predictor variables (team invited parent to speak, nurse presence), and other encounter-related variables. Parents were surveyed to assess parent and child characteristics and experiences during FCR. We examined parent, child, and encounter characteristic associations with the above outcomes using bivariate analyses and (for those associated in bivariate analyses) Poisson regressions. RESULTS:Inviting the parent to speak was independently associated with the number of questions asked (incident rate ratio [IRR] 1.4; 95% confidence interval [CI] 1.1-1.7). Trusting the medical team was inversely associated with questions asked (IRR 0.8; 95% CI 0.6-0.97). Factors associated with total participation included invitation for the parent to speak (IRR 1.5; 95% CI 1.3-1.6), nurse presence (IRR 1.3; 95% CI 1.1-1.5), white race (IRR 1.2; 95% CI 1.1-1.4), clerkship student presentation (IRR 1.2; 95% CI 1.03-1.3), and parent inclusion in rounding arrangement (IRR 1.5; 95% CI 1.05-2). CONCLUSIONS:Parents present during FCR are more engaged when invited to speak. Nurse presence was associated with total parent participation. Future studies to inform interventions to optimize engagement are warranted.
PMID: 33303474
ISSN: 2154-1671
CID: 4709252

Cultivating a New Generation of Biomedical Entrepreneurs

Gold-von Simson, Gabrielle; Gilon-Yanai, Michal; Gillespie, Colleen; Chitale, Sadhana; Achuonjei, Joy; Cobos, Daniel
In recent years, scientific and technological advances have brought great innovation within the life sciences industry, introducing the need for entrepreneurship training for medical and engineering graduates. With this in mind, Michal Gilon-Yanai, Dr Robert Schneider and their collaborators developed an academic program designed to provide students and faculty members with the skills they need to become successful entrepreneurs. The team of collaborators includes Dr Gabrielle Gold-von Simson, an expert in implementing academic programs, and Dr Colleen Gillespie, who specialises in education, evaluation and dissemination science. Their pioneering program trains students on how to bring new biomedical technologies to the market.
PMCID:8240592
PMID: 34194817
ISSN: 2059-898x
CID: 4926842

Improving Birth Dose Hepatitis B Vaccination Rates: A Quality Improvement Intervention

Bradshaw, Chanda; DiFrisco, Eileen; Schweizer, William; Pavsic, Joy; Demarco, Kathleen; Weckesser, Jane; Gold-VonSimson, Gabrielle; Rosenberg, Rebecca E
BACKGROUND:There are 43 000 new cases of hepatitis B virus infection and 1000 cases of perinatally acquired infection each year in the United States. National recommendations are to administer hepatitis B (HepB) vaccine to all stable newborns >2000 g within 24 hours of birth. Our primary objective was to increase institutional vaccination rates from a baseline of 52% to goal >85% before hospital discharge. METHODS:In February 2017, we instituted a multidisciplinary quality improvement project aimed at increasing HepB vaccination birth dose rates. Interventions included (1) standardizing the process of offering HepB vaccine via scripting and timing, (2) engaging and educating parents, and (3) educating physicians and nurses regarding the importance of HepB vaccination and strategies to discuss HepB vaccination with vaccine-hesitant parents. The main outcome measure was the percentage of newborns receiving HepB vaccination by discharge. The secondary outcome was the percentage of newborns receiving HepB vaccination by 12 hours of life per New York State Department of Health recommendation. Data were analyzed by using statistical process control P-charts. RESULTS:A total of 21 108 newborns were included between July 2015 and April 2019. In addition to several upward centerline shifts, implementation of interventions resulted in increased and sustained HepB vaccination rates by hospital discharge from a baseline of 52.4% to 72.5%. Rates by 12 hours of life increased from 21.5% to 42.5%. CONCLUSIONS:Multidisciplinary collaboration, scripting, and provider and staff education regarding the risks of hepatitis B virus, benefits of HepB vaccine, and strategies to discuss HepB vaccination with parents significantly increased vaccination rates. Further efforts to improve vaccination rates to within 12 hours are preferable.
PMID: 32341000
ISSN: 2154-1671
CID: 4436852