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Pharmacotherapy for Perinatal Depression

Lusskin, Shari I; Khan, Sabrina J; Ernst, Carrie; Habib, Sally; Fersh, Madeleine E; Albertini, Elizabeth S
Perinatal depression is associated with serious risks for the mother, baby, and family. When considering treating perinatal depression with a drug indicated for the treatment of depression, the major concerns are whether the drug increases the risks of teratogenicity, pregnancy complications, poor neonatal adaptation, or neurodevelopmental disorders. Although different studies have produced different results, the majority have not shown increases in risk for selective serotonin reuptake inhibitors, serotonin norepinephrine reuptake inhibitors, tricyclic antidepressants, or the noradrenergic/dopaminergic drug bupropion. In this review we will discuss the reproductive safety data for these medications as well as monoamine oxidase inhibitors and benzodiazepines.
PMID: 29561284
ISSN: 1532-5520
CID: 3001472

Severe Prolonged Encephalopathy from an Intentional Lamotrigine Overdose with Significantly Elevated and Prolonged Serum Concentrations [Meeting Abstract]

Hernandez, SH; Habib, S; Howland, MA; Hoffman, RS; Nelson, LS
ISI:000283492900218
ISSN: 1556-3650
CID: 2786582

Perinatal depression: hiding in plain sight

Lusskin, Shari I; Pundiak, Tara M; Habib, Sally M
OBJECTIVE: To promote prompt identification and treatment ofperinatal depression and enhance preventive care for women at risk. METHODS: Using MEDLINE and PubMed searches, we reviewed the recent research on the origins, course, and consequences of pregnancy-related depression. RESULTS: Depressive disorders are more common in pregnancy and postpartum than widely assumed, and there is no predictable protective effect of pregnancy. Relapse rates are high, and the postpartum period represents a time of increased vulnerability to depression. CONCLUSION: Early identification and treatment ofperinatal depression will minimize morbidity and mortality for the woman, the child, and the family
PMID: 17955909
ISSN: 0706-7437
CID: 75397

"Perinatal depression: Hiding in plain sight": Erratum [Correction]

Lusskin, Shari I; Pundiak, Tara M; Habib, Sally M
Reports an error in 'Perinatal depression: Hiding in plain sight' by Shari I. Lusskin, Tara M. Pundiak and Sally M. Habib (The Canadian Journal of Psychiatry / La Revue Canadienne de Psychiatrie, 2007[Aug], Vol 52[8], 479-488). It has come to the authors' attention that the prevalence of postpartum depression among new immigrants to Israel was incorrectly reported as 22.6% rather than 35.8%. The prevalence rate for the entire study group of 288 Israeli women was 22.6%; two-thirds of the entire group reported symptoms during pregnancy. Among new Russian immigrants, the prevalence of postpartum depression was 35.8%, twice the rate (16.9%) of Israeli-born women; rates of antenatal symptoms for this subgroup were not reported. These findings highlight the importance of assessing individual risk factors for perinatal depression. The Canadian Journal of Psychiatry regrets the error and any inconvenience it may have caused. (The following abstract of the original article appeared in record 2007-14436-002). Objective: To promote prompt identification and treatment of perinatal depression and enhance preventive care for women at risk. Methods: Using MEDLINE and PubMed searches, we reviewed the recent research on the origins, course, and consequences of pregnancy-related depression. Results: Depressive disorders are more common in pregnancy and postpartum than widely assumed, and there is no predictable protective effect of pregnancy. Relapse rates are high, and the postpartum period represents a time of increased vulnerability to depression. Conclusion: Early identification and treatment of perinatal depression will minimize morbidity and mortality for the woman, the child, and the family.
PSYCH:2007-17971-002
ISSN: 0706-7437
CID: 75227