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The Treatment of Co-Occurring Post-Traumatic Stress Disorder and Substance Use Disorders

Chapter by: Stiffler, J David; Hennessy, Grace
in: Co-occurring mental illness and substance use disorders : a guide to diagnosis and treatment by Avery, Jonathan D; Barnhill, John W (Eds)
Arlington, VA : American Psychiatric Association Publishing, [2018]
pp. 49-68
ISBN: 9781615371594
CID: 3696792

Caffeine

Chapter by: Hennessy, Grace
in: Pocket guide to addiction assessment and treatment by Levounis, Petros; Zerbo, Erin; Aggarwal, Rashi [Eds]
Arlington, VA : American Psychiatric Association Publishing, [2016]
pp. ?-?
ISBN: 1585625124
CID: 2594432

Caffeine

Chapter by: Hennessy, Grace
in: Pocket guide to addiction assessment and treatment by Levounis, Petros; Zerbo, Erin; Aggarwal, Rashi [Eds]
Arlington, VA: American Psychiatric Association Publishing, 2016
pp. 97-108
ISBN: 978-1-58562-512-3
CID: 2626602

Assessment of the patient

Chapter by: Greenfield, Shelly F; Hennessy, Grace
in: The American Psychiatric Publishing textbook of substance abuse treatment by Galanter, Marc; Kleber, Herbert D; Brady, Kathleen T [Eds]
Arlington, VA : American Psychiatric Publishing, Inc.; US, 2015
pp. 81-97
ISBN: 978-1-58562-472-0
CID: 1645292

Atomoxetine Treatment for Cocaine Abuse and Adult Attention-Deficit Hyperactivity Disorder (ADHD): A Preliminary Open Trial

Levin, Frances R; Mariani, John J; Secora, Alex; Brooks, Daniel; Cheng, Wendy Y; Bisaga, Adam; Nunes, Edward; Aharonovich, Efrat; Raby, Wilfrid; Hennessy, Grace
The purpose of this 12-week open trial was to evaluate the potential utility of atomoxetine for the treatment of attention deficit hyperactivity disorder (ADHD) in cocaine-dependent treatment seekers. The sample consisted of 20 participants with all participants meeting DSM-IV-TR criteria for ADHD and cocaine dependence (CD). Using several measures to assess ADHD, there was a significant reduction in ADHD symptoms. There was no significant decrease in cocaine use throughout the trial. Taken together, although cocaine-dependent individuals showed some reduction in ADHD symptoms while receiving atomoxetine, the high drop-out rate and lack of impact on cocaine use may limit its utility in ADHD adults who are currently abusing cocaine.
PMCID:2679511
PMID: 19430599
ISSN: 1550-4271
CID: 394482

Treatment of patients with substance use disorders, second edition. American Psychiatric Association [Guideline]

Kleber, Herbert D; Weiss, Roger D; Anton, Raymond F Jr; George, Tony P; Greenfield, Shelly F; Kosten, Thomas R; O'Brien, Charles P; Rounsaville, Bruce J; Strain, Eric C; Ziedonis, Douglas M; Hennessy, Grace; Connery, Hilary Smith; McIntyre, John S; Charles, Sara C; Anzia, Daniel J; Cook, Ian A; Finnerty, Molly T; Johnson, Bradley R; Nininger, James E; Summergrad, Paul; Woods, Sherwyn M; Yager, Joel; Pyles, Robert; Cross, C Deborah; Peele, Roger; Shemo, John P D; Lurie, Lawrence; Walker, R Dale; Barnovitz, Mary Ann; Gray, Sheila Hafter; Saxena, Sunil; Tonnu, Tina; Kunkle, Robert; Albert, Amy B; Fochtmann, Laura J; Hart, Claudia; Regier, Darrel
PMID: 17569411
ISSN: 0002-953x
CID: 219532

Treatment of patients with substance use disorders, second edition. American Psychiatic Association [Guideline]

Kleber, Herbert D; Weiss, Roger D; Anton, Raymond F; Rounsaville, Bruce J; George, Tony P; Strain, Eric C; Greenfield, Shelly F; Ziedonis, Douglas M; Kosten, Thomas R; Hennessy, Grace; O'Brien, Charles P; Connery, Hilary Smith; McIntyre, John S; Charles, Sara C; Anzia, Daniel J; Nininger, James E; Cook, Ian A; Summergrad, Paul; Finnerty, Molly T; Woods, Sherwyn M; Johnson, Bradley R; Yager, Joel; Pyles, Robert; Lurie, Lawrence; Cross, C Deborah; Walker, R Dale; Peele, Roger; Barnovitz, Mary Ann; Gray, Sheila Hafter; Shemo, John P D; Saxena, Sunil; Tonnu, Tina; Kunkle, Robert; Albert, Amy B; Fochtmann, Laura J; Hart, Claudia; Regier, Darrel
PMID: 16981488
ISSN: 0002-953x
CID: 219482

Bipolar disorder and substance abuse

Levin, Frances R; Hennessy, Grace
Substance use disorders are overrepresented in individuals with bipolar and bipolar spectrum disorders. Although awareness of this phenomenon has increased over the past 20 years, few empirically based treatment strategies have been developed for this challenging patient population. This review examines the relationship between bipolar and substance use disorders and treatment options that have been studied in this patient population. First, we examine the high prevalence rates of substance use disorders in individuals diagnosed with bipolar disorder, the common problems associated with establishing a bipolar disorder diagnosis in individuals who abuse substances, the possible explanations for the frequent coexistence of bipolar and substance use disorders, and the negative effect of substance abuse on the course of and treatment outcomes for bipolar disorder. The review then focuses on treatment approaches for this patient population, including integrated group therapy for co-occurring bipolar and substance use disorders and pharmacotherapies that target both disorders. Finally, we present suggestions for medications that might be tested for their efficacy in treating both disorders in specific subgroups of patients with bipolar and substance use disorders.
PMID: 15556118
ISSN: 0006-3223
CID: 394492

Substance use histories in patients seeking treatment for controlled-release oxycodone dependence

Potter, Jennifer Sharpe; Hennessy, Grace; Borrow, Jennifer A; Greenfield, Shelly F; Weiss, Roger D
The characteristics of patients currently abusing controlled-release (CR) oxycodone admitted for inpatient detoxification were ascertained from medical record review of 48 inpatients with CR oxycodone dependence. Patients were categorized according to the manner in which they initially received the drug: illicitly or by prescription for legitimate medical use. Fifteen of the 48 patients (31%) initially obtained a CR oxycodone prescription legitimately for a medical condition. While none of these 15 patients had a history of prior opioid misuse, they were more likely than illicit CR oxycodone users to report prior detoxifications (P<0.03) as well as a lower mean age of first alcohol use (legitimate=11.7 versus illicit=14.7, P<0.05) and first illicit drug use (legitimate=12.8 versus illicit=15.8, P<0.05). These findings suggest that a history of substance abuse is common among patients abusing CR oxycodone, including individuals for whom CR oxycodone was initially legitimately prescribed for pain.
PMID: 15488345
ISSN: 0376-8716
CID: 394502

Psychosocial treatments for cocaine dependence

Hennessy, Grace O'Leary; De Menil, Victoria; Weiss, Roger D
Psychosocial treatment remains the predominant modality of treatment for patients with cocaine dependence. This paper reviews several recent studies comparing different types of psychosocial treatments for this population. A number of forms of psychosocial treatment for cocaine dependence have shown promising results, as detailed in the study descriptions.
PMID: 13678556
ISSN: 1523-3812
CID: 978632