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Objective and quantitative improvement of rosacea-associated erythema after intense pulsed light treatment

Mark, Kenneth A; Sparacio, Rose Marie; Voigt, Audra; Marenus, Kenneth; Sarnoff, Deborah S
BACKGROUND: Despite the widespread and quite successful use of various lasers and light sources to treat facial erythema, the literature contains little, if any, objective and quantitative improvement. In addition, very few studies specifically address rosacea-associated erythema. OBJECTIVE: To assess quantitatively the degree of improvement in patients with rosacea after intense pulsed light treatment. The three main parameters that were objectively measured were blood flow, telangiectasia, and erythema. METHODS: Four patients with rosacea-associated erythema and telangiectasia were treated five times at 3-week intervals with the Photoderm VL (Lumenis, Needham, MA). The 515-nm filter, a single pulse duration of 3 ms, and various fluences were used. Blood flow was measured by the scanning laser Doppler. Close-up photography ensured reproducibility and enabled quantification of telangiectasia and erythema by subsequent computer image analysis. Measurements were taken at baseline and at 1 month after the last treatment. RESULTS: The scanning laser Doppler demonstrated a 30% decrease in blood flow (P<0.05). A 29% decrease in actual area of the cheek occupied by telangiectasia was noted (P<0.05). A 21% decrease in the intensity of erythema was noted (P<0.05). CONCLUSION: As demonstrated by truly objective and quantitative means, intense pulsed light is effective for reducing rosacea-associated blood flow, telangiectasia, and erythema
PMID: 12786702
ISSN: 1076-0512
CID: 39210

Colchicine and indomethacin for the treatment of relapsing polychondritis [Case Report]

Mark, Kenneth A; Franks, Andrew G Jr
This report describes the effectiveness of oral colchicine and indomethacin in the maintenance phase of treatment of relapsing polychondritis. Systemic corticosteroids are commonly used in the induction phase of managing cases of relapsing polychondritis. Clinicians are then faced with the challenge of controlling the patient's symptoms while trying to decrease the dose of steroid
PMID: 11807462
ISSN: 0190-9622
CID: 27408

In favor of antibiotic prophylaxis for laser resurfacing [4]

Mark KA; Sarnoff DS
EMBASE:2001323527
ISSN: 0003-987x
CID: 26873

Squamous cell carcinoma and actinic keratosis

Chapter by: Mark KA; Sarnoff DS
in: Current dermatologic diagnosis & treatment by Freedberg IM; Sanchez MR [Eds]
Philadelphia : Lippincott Williams & Wilkins, 2001
pp. 200-201
ISBN: 0781735319
CID: 3760

Role for blast HAART therapy at term for poorly adherent HIV positive mothers [Meeting Abstract]

Smith-Levitin, M; Mark, K; Bautista, M
ISI:000172921000391
ISSN: 0002-9378
CID: 2060682

Allergic contact and photoallergic contact dermatitis to plant and pesticide allergens [Case Report]

Mark KA; Brancaccio RR; Soter NA; Cohen DE
BACKGROUND: The panel of patch test allergens used for the evaluation of patients with suspected photoallergy typically does not include plant and pesticide allergens. The prevalence of allergic contact dermatitis and photoallergic contact dermatitis to plant and pesticide allergens was determined for this subgroup of patients. OBSERVATION: Positive reactions were detected in 12 of 26 patients who were tested with our photoallergen series: 5 with allergic contact dermatitis, 5 with photoallergic contact dermatitis, and 2 with both. Four of the 12 patients had positive patch and photo-patch test reactions to plant allergens, pesticide allergens, or both. The positive patch test reactions were to the plants Taraxacum officinale (dandelion) and Tanacetum vulgare (tansy) and to the pesticides folpet and captafol. Positive photo-patch test reactions were to the pesticides folpet and captan. The histories of the patients suggested that 2 or 3 of the 4 patients had clinically relevant reactions. In the other 8 patients, positive reactions to the patch and photo-patch tests included fragrances, sunscreens, and antibacterial agents. CONCLUSION: Plant and pesticide allergens should be included in the patch and photo-patch test series used for the evaluation of patients with suspected photoallergy
PMID: 9923784
ISSN: 0003-987x
CID: 7401

Mind-body medicine. Practical applications in dermatology

Bilkis MR; Mark KA
It is only recently that Western physicians are rediscovering the link between thought and health. The spectrum of causative factors in inflammatory dermatoses are often multifactorial. Stress and negative thoughts are major factors in dermatologic conditions. This article begins with some basic information on the ways that thoughts affect health. Practical methods of intervention including meditation, journal writing, affirmations, prayer, biofeedback, and hypnosis are presented
PMID: 9828881
ISSN: 0003-987x
CID: 7499

PERIODONTAL-DISEASE IN HIV+ AND HIV- INTRAVENOUS-DRUG-USERS [Meeting Abstract]

LOPEZ, M; BARR, C; KAIM, J; VITI, A; MARK, K
ISI:A1994MT32502254
ISSN: 0022-0345
CID: 2734452