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Multimodality Imaging of Myocardial Viability

Parikh, Kinjan; Choy-Shan, Alana; Ghesani, Munir; Donnino, Robert
PURPOSE OF REVIEW/OBJECTIVE:Myocardial viability is an important pathophysiologic concept which may have significant clinical impact in patients with left ventricular dysfunction due to ischemic heart disease. Understanding the imaging modalities used to assess viability, and the clinical implication of their findings, is critical for clinical decision-making in this population. RECENT FINDINGS/RESULTS:The ability of dobutamine echocardiography, single-photon emission computed tomography, positron emission tomography, and cardiac magnetic resonance imaging to predict functional recovery following revascularization is well-established. Despite different advantages and disadvantages for each imaging modality, each modality has demonstrated reasonable performance characteristics in identifying viable myocardium. Recent data, however, has called into question whether this functional recovery leads to improved clinical outcomes. Although the assessment of viability can be used to aid in clinical decision-making prior to revascularization, its broad application to all patients is limited by a lack of data confirming improvement in clinical outcomes. Thus, viability assessments may be best applied to select patients (such as those with increased surgical risk) and integrated with clinical, laboratory, and imaging data to guide clinical care. Future research efforts should be aimed at establishing the impact of viability on clinical outcomes.
PMID: 33398512
ISSN: 1534-3170
CID: 4759312

Revisiting Atrial Fibrillation in the Transcatheter Aortic Valve Replacement Era

Parikh, Kinjan; Dizon, Jose; Biviano, Angelo
Atrial fibrillation (AF) is a known complication of many cardiac procedures, including those undergoing surgical aortic valve replacement (SAVR). In the transcatheter aortic valve replacement (TAVR) era, AF has been noted not only to be present in these patients but also associated with morbidity and mortality. In this article, we first outline the significance of AF in general and then more specifically in patients undergoing cardiac surgery. We then compare and contrast specific clinical issues related to AF in patients with aortic stenosis undergoing aortic valve replacement, traditionally with SAVR, but now increasingly more common with TAVR.
PMID: 30274612
ISSN: 2211-7466
CID: 5309562

Should We Up the Intensity of Statin Therapy After Placing a Drug-eluting Stent? [Editorial]

Parikh, Kinjan H; Kirtane, Ajay J
PMID: 29104001
ISSN: 1885-5857
CID: 5309552

Feasibility of Chronic Total Occlusion Recanalization During Balloon Pulmonary Angioplasty [Meeting Abstract]

Sethi, Sanjum; Parikh, Kinjan; Rosenzweig, Erika Berman; Bacchetta, Matthew; Torres, Alejandro; Green, Philip; Fall, Khady; Ishida, Masaru; Maehara, Akiko; Karmpaliotis, Dimitri; Kirtane, Ajay Jayant
ISI:000455137100161
ISSN: 0735-1097
CID: 5309572