Faculty Bibliography

Indium-111-labeled white blood scan is a highly sensitive imaging technique using radiolabeled leukocytes in the detection of occult infection. We present two cases of occult sinusitis-identified with the use of the white blood cell scan. The literature on the subject is reviewed, and indications for the use of white blood cell scans in the detection of sinusitis are discussed

Acquired factor VIII deficiency is a rare immunologic disorder characterized by severe bleeding due to an antibody inhibitor directed against factor VIII. Treatment of this coagulopathy often is ineffective and costly. The authors report a case of acquired factor VIII deficiency in a patient who developed severe recurrent epistaxis. Antifibrinolytic therapy with epsilon aminocaproic acid (EACA) was used to control the epistaxis with excellent results. To the authors' knowledge, this is the first report of the efficacy of EACA therapy in acquired factor VIII deficiency. Use of antifibrinolytic therapy may represent a relatively safe, effective, and inexpensive approach to treating factor VIII inhibitors