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9


Status of secondary prevention in patients undergoing coronary revascularization

Allen, J K; Blumenthal, R S; Margolis, S; Young, D R
PMID: 11356400
ISSN: 0002-9149
CID: 3867112

Bilateral optic disc neovascularization in association with retinitis pigmentosa [Case Report]

To KW; Nadel AJ; Perlstein SH; Margolis S
Bilateral neovascularization of the optic disc developed in a 16-year-old Hispanic girl with retinitis pigmentosa. The neovascularization regressed in both eyes over 1 year without treatment. Ocular and systemic evaluation failed to reveal a recognized cause for the neovascularization. To our knowledge this is only the third case reported of this unusual association
PMID: 2054727
ISSN: 0008-4182
CID: 22355

The golden tapetal sheen reflex in retinal disease [Case Report]

Noble KG; Margolis S; Carr RE
A mother and son with dominant cone dystrophy manifested the retinal reflexes seen in Oguchi's disease (mother) and the carrier female of X-linked retinitis pigmentosa (son). Another patient with cone dystrophy (simplex) showed localized areas of a golden reflex in each eye. A patient with juvenile macular dystrophy exhibited a diffuse golden-orange reflex throughout the posterior pole. The latter two patients did not have the Mizuo phenomenon
PMID: 2923149
ISSN: 0002-9394
CID: 10697

Variable expressivity in fundus albipunctatus [Case Report]

Margolis, S; Siegel, I M; Ripps, H
A healthy, 14-year-old girl presented with nyctalopia, good vision, and multiple, irregular, yellowish lesions of the fundus. Dark adaptometry showed prolonged cone and rod branches, elevated thresholds, and the cone-rod transition occurring after 50 minutes in darkness. Her scotopic electroretinogram (ERG) b-wave attained normal amplitudes after 45 minutes of dark adaptation. The half-time for regeneration of rhodopsin after an extensive bleach was 16 minutes, four times longer than normal, and the maximum density difference measured by fundus reflectometry was at the lower limit of the normal range. Although photopigment kinetics were significantly faster than observed in other reported cases of fundus albipunctatus, it appears likely that there is a wide spectrum of functional and funduscopic abnormalities in this disorder. However, fundus appearance, adaptometric findings, and rhodopsin determinations serve to distinguish fundus albipunctatus from other flecked retina diseases.
PMID: 3500444
ISSN: 0161-6420
CID: 160598

Retinal and optic nerve findings in Goldenhar-Gorlin syndrome [Case Report]

Margolis S; Aleksic S; Charles N; McCarthy J; Greco A; Budzilovich G
Involvement of the posterior segment of the eye in Goldenhar-Gorlin syndrome is more common than is generally appreciated. We examined seven patients with this syndrome. Abnormalities included diminished visual acuity, tilted optic disc, optic nerve hypoplasia, tortuous retinal vessels, macular hypoplasia and heterotopia, microphthalmia and anophthalmia. In one case, pathologic study showed agenesis of the optic nerve. It is proposed that retinal, optic nerve and craniofacial abnormalities in this condition may reflect an asynchrony in the migration of the neural crest cells in the early stages of embryonal development
PMID: 6514297
ISSN: 0161-6420
CID: 63352

Intracranial lipomas, hydrocephalus and other CNS anomalies in oculoauriculo-vertebral dysplasia (Goldenhar-Gorlin syndrome)

Aleksic, S; Budzilovich, G; Greco, M A; McCarthy, J; Reuben, R; Margolis, S; Epstein, F; Feigin, I; Pearson, J
13 cases of Goldenhar-Gorlin syndrome are presented in which numerous central nervous system anomalies have been found. These include occipital encephalocele, hydrocephalus, aqueductal stenosis, agenesis of corpus callosum, multiple congenital lipomas and many others. Pertinent literature has been reviewed. It is concluded that any part of the central nervous system can be involved in this condition and that careful evaluation is indicated in order to rule out a treatable intracranial anomaly
PMID: 6499566
ISSN: 0302-2803
CID: 117276

Effect of cycloheximide on corticosteroid-induced changes in

Zorgniotti, A W; Adler, L; Peselow, E; Corwin, J; Rotrosen, J University Medical Center and Psychiatry Service, Veterans Administration Medical Center, New York, NY 10016 United States; Aleksic, S; Greco, M A; Reuben, R; Margolis, S; Epstein, F; Feigin, I; Charney, A N; Wallach, J D; Donowitz, M; Johnstone, N
13 cases of Goldenhar-Gorlin syndrome are presented in which numerous central nervous system anomalies have been found. These others. Pertinent literature has been reviewed. It is concluded that any part of the central nervous system can be involved in this condition and that careful evaluation is indicated in order to rule
EMBASE:22024188
ISSN: 0007-1250
CID: 4775032

Anophthalmia in an infant of parents using LSD [Case Report]

Margolis, S; Martin, L
We have described a unilateral anophthalmia in an infant with normal chromosome studies born to parents who took LSD before and during pregnancy. In view of the lack of any other fetal abnormalities in this child, known to be associated with LSD, we report this case to suggest that anophthalmia may be a new drug-related defect. A complete drug history of the parents should be taken in cases of congenital abnormalities to accumulates further data, which will point conclusively to the etiology of anophthalmia and possibly other congenital defects.
PMID: 7224497
ISSN: 0003-4886
CID: 577662

A gold foil electrode: extending the horizons for clinical electroretinography

Arden, G B; Carter, R M; Hogg, C; Siegel, I M; Margolis, S
A gold foil ERG electrode is described. The device is inexpensive and simple to fabricate. Since it is hooked over the lower lid and makes minimal touch contact with the inferior limbal area, it can be used in circumstances which require prolonged testing of retinal function or in eyes with corneal pathology. Because the optics of the eye are not compromised, it is possible, with the use of appropriate stimuli and response-averaging techniques, to record local EFGs from relatively small retinal areas.
PMID: 311765
ISSN: 0146-0404
CID: 318982