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Comparision of Standard Skin-Sparing Mastectomy to Inverted-T Pattern Mastectomy in Patients Undergoing 2-Stage Implant Reconstruction [Meeting Abstract]

Kaufman, Gabriel; Baranchuk, Nadia; Monteleone, Frank; Logman, Zhanna; Douglas, Barry; Brewer, Bruce; Kilgo, Matt
ISI:000318174800087
ISSN: 1068-9265
CID: 3537482

Uremic autonomic neuropathy studied by spectral analysis of heart rate

Vita, G; Bellinghieri, G; Trusso, A; Costantino, G; Santoro, D; Monteleone, F; Messina, C; Savica, V
BACKGROUND:There is good evidence that power spectral analysis (PSA) of heart rate variability may provide an insight into the understanding of autonomic disorders. METHODS:We investigated 30 chronic uremic patients who were on periodic bicarbonate hemodialysis by a battery of six cardiovascular autonomic tests (beat-to-beat variations during quiet breathing and deep breathing, heart rate responses to the Valsalva maneuver and standing, blood pressure responses to standing and sustained handgrip) and PSA of heart rate variations. RESULTS:Eleven patients (37%) had an abnormal response to only one parasympathetic test. Twelve patients (40%) had a definite parasympathetic damage, as indicated by at least two abnormal heart rate tests, whereas four (13%) had combined parasympathetic and sympathetic damage. Multivariate analysis of the cardiovascular tests revealed that 19 patients (63%) had moderate-to-severe autonomic neuropathy (AN), and 11 patients exhibited normal autonomic function. Among the symptoms suggestive of autonomic dysfunction, only impotence in males was significantly associated with test-proven AN. The PSA of the heart rate variability demonstrated a good discrimination of low-frequency (LF) and high-frequency (HF) bands (LF, 0.03 to 0.15 Hz; HF, 0.15 to 0.33 Hz) among controls, uremic patients without test-proven AN, and uremic patients with test-proven AN. A significant reduction of the LF value on supine uremic patients without AN suggests that an early sympathetic involvement exists that traditional autonomic tests were unable to detect. CONCLUSIONS:Our study indicates that the current opinion of a major parasympathetic damage in chronic uremic patients on hemodialysis has to be modified in favor of a more widespread autonomic dysfunction involving both the sympathetic and parasympathetic pathways.
PMID: 10411697
ISSN: 0085-2538
CID: 3357112

Splenic vein aneurysm: is it a surgical indication? [Case Report]

Torres, G; Hines, G L; Monteleone, F; Hon, M; Diel, J
Splenic vein aneurysms are rare and are usually caused by portal hypertension. Symptoms are unusual, but may include rupture or abdominal pain. Diagnosis can usually be made either by means of duplex ultrasonography or computed tomography scanning. Treatment varies from noninvasive follow-up to aneurysm excision. We report an expanding splenic vein aneurysm in a young woman with abdominal and back pain and no history of portal hypertension. She was treated with aneurysm excision and splenectomy.
PMID: 10194502
ISSN: 0741-5214
CID: 3003552

Concurrent right atrial myxoma and malignant lymphoma [Case Report]

Connery, C P; Khalife, M E; Monteleone, F A; Schuss, A F; Ger, R
Atrial myxomas are the most common primary tumor of the heart. We report an unusual case where an incidentally found right atrial myxoma was associated with a malignant lymphoma. Surgical management of the concurrent problems is discussed as well as a review of pertinent literature and efficacy of diagnostic modalities.
PMID: 8632026
ISSN: 0021-9509
CID: 3357122

Extraskeletal osteosarcoma: light and electron microscopic study [Case Report]

Waxman, M; Vuletin, J C; Saxe, B I; Monteleone, F A
PMID: 6975882
ISSN: 0027-2507
CID: 3357142

Adrenal ablation

Janelli, D E; Monteleone, F; Mishrick, A; Kashiwabara, H
Of 135 patients who had bilateral adrenalectomies for metastatic breast cancer, 110 could be evaluated and 63 patients (57.3%) responded (43 objective, 20 subjective responders). Patients aged 31 to 45 years had a 56% response rate; 58% of patients aged 46 to 70 responded. Oophorectomy responders benefited from adrenalectomy 62% of the time and oophorectomy failures reponded in 38% of the cases. Patients with a disease-free interval of zero to 2.5 years responded to adrenalectomy at a rate of 46%, whereas patients with a free interval greater than 2.5 years responded at a rate of 73%. The median survival rate of 63 adrenalectomy responders was 28 months; it was ten months for 47 nonresponders.
PMID: 94043
ISSN: 0020-8868
CID: 3357132