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Borderline Personality Disorder: Updates in a Postpandemic World

Choi-Kain, Lois W; Sahin, Zeynep; Traynor, Jenna
ORIGINAL:0016214
ISSN: 1541-4094
CID: 5355002

Beyond symptom reduction: Development and validation of the Complementary Measure of Psychotherapy Outcome (COMPO)

Chui, Harold; Chong, Eddie S K; Atzil-Slonim, Dana; Sahin, Zeynep; Solomonov, Nili; Minges, Mary V; Kuprian, Nadia; Barber, Jacques P
Most measures of psychotherapy outcome focus on symptomatic change. However, clients often report other changes through therapy, such as increased self-acceptance. This study reports on the development and validation of the Complementary Measure of Psychotherapy Outcome (COMPO) that assesses different areas of psychological functioning deemed important by clients and therapists. Items were written based on a literature review of client-reported change and feedback from experienced therapists. Exploratory factor analysis was conducted on the initial 42-item COMPO administered to 264 psychotherapy clients. Iterative item reduction resulted in the final 12-item, four-factor solution, with factors named self-acceptance, self-knowledge, relationship quality, and consideration of others. This factor structure, along with a bifactor model that contains a general factor and the four domain-specific factors, was replicated on a sample of 571 adults in the community. The 12-item COMPO exhibits convergent validity with measures of self-esteem, insight, social support, and empathy; demonstrates 2-week test-retest reliability; and predicts life satisfaction. The 12-item COMPO was further administered to 28 clients in short-term psychodynamic therapy for depression. Except for consideration of others, COMPO subscales and total scale scores improved from pre- to posttherapy. Posttherapy COMPO scores were also higher among clients who experienced clinically significant change compared to those who did not. The COMPO was negatively associated with depressive symptoms and impairments in functioning across the three samples. The brevity of the COMPO makes it a convenient tool to supplement symptom-based measures for a more comprehensive assessment of outcome in psychotherapy. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
PMID: 33090871
ISSN: 0022-0167
CID: 4642862

A meta-analysis of psychodynamic treatments for borderline and cluster C personality disorders

Keefe, John R; McMain, Shelley F; McCarthy, Kevin S; Zilcha-Mano, Sigal; Dinger, Ulrike; Sahin, Zeynep; Graham, Kathryn; Barber, Jacques P
Personality disorders (PD) carry high psychosocial dysfunction and are associated with treatment resistance in nonspecialized care. Psychodynamic therapies (PDT) are often used to treat PDs, but there has never been a systematic meta-analysis of PDT trials for PD. To evaluate the evidence base for PDTs for PDs across multiple outcome domain, a systematic search for PDT for PD trials was conducted through PubMed and PsycINFO. Sixteen trials were identified, comprising 19 dynamic, 8 active, and 9 control groups predominantly reflecting treatment of borderline and mixed Cluster C PDs, and a random effects meta-analysis was undertaken. PDTs were superior to controls in improving core PD symptoms (g = -0.63; 95% confidence interval [CI; -0.87, -0.41]), suicidality (g = -0.79, p = .02; 95% CI [-1.38, -0.20]), general psychiatric symptoms (g = -0.47; 95% CI [-0.69, -0.25]), and functioning (g = -0.66; 95% CI [-1.01, -0.32]), but not for interpersonal problems due to heterogeneity (g = -1.25; 95% CI [-3.22, 0.71]). Outcomes for PDTs were not different from other active treatments in core PD (g = 0.05; 95% CI [-0.25, 0.35]) or other symptoms. This pattern continued into posttreatment follow-up (average 14 months). Study quality was generally rated as adequate and was unrelated to outcomes. Compared with other treatments, PDTs do not have different acute effects and are superior to controls, although only trials treating BPD employed active controls and non-BPD trials were of lower quality. Underresearched areas include narcissistic PD, specific Cluster C disorders, and personality pathology as a continuous construct. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
PMID: 31804128
ISSN: 1949-2723
CID: 4485732

Clinical severity as a moderator of outcome in psychodynamic and dialectical behavior therapies for borderline personality disorder

Sahin, Zeynep; Vinnars, Bo; Gorman, Bernard S; Wilczek, Alexander; Ã…sberg, Marie; Barber, Jacques P
The aim of the present study was to assess the effect of initial level of psychiatric severity on treatment outcome in psychodynamic therapy and dialectical behavior therapy (DBT) for borderline personality disorder (BPD). It was hypothesized that DBT would lead to better outcome for patients with high psychiatric severity, whereas dynamic treatment would lead to better outcome for patients with lower psychiatric severity. Data from the 5th-year follow-up of the Stockholm City Council's and the Karolinska Institute's Psychotherapy Project were used in the present study. A total of 106 female patients diagnosed with BPD with at least 2 past suicide attempts were randomized into object-relational psychotherapy (ORP; based on transference-focused psychotherapy), DBT, and treatment as usual. Patients' baseline global severity index was used as a moderator. Global Assessment of Functioning (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition [American Psychiatric Association, 1994]) was used to examine outcome. There was a significant 3-way interaction of Time × Treatment × Severity. Post hoc analyses suggested that patients with lower levels of severity had significantly better outcomes in object-relational psychotherapy. For patients with higher severity, the 3 treatments resulted in similar outcomes in terms of level of functioning. Outcome of treatment for BPD might differ significantly for patients depending on their initial levels of overall psychiatric severity. If our findings are replicated for patients with low severity and supported for a high-severity sample, psychiatric severity can be used as a low-cost and effective tool to match patients with BPD to optimal treatments. (PsycINFO Database Record
PMID: 29239627
ISSN: 1949-2723
CID: 4802022

Termination of Treatment

Chapter by: Sahin, Zeynep; Barber, Jacques P
in: The SAGE encyclopedia of abnormal and clinical psychology by Wenzel, Amy (Ed)
Los Angeles : SAGE Reference, [2017]
pp. ?-?
ISBN: 1483365832
CID: 5418502

Supportive expressive dynamic therapy : an update

Chapter by: Sahin, Zeynep; Barber, JP; Luborsky, L
in: Reference module in neuroscience and biobehavioral psychology by Stein, John (Ed)
[S.l.] : Elsevier, 2017
pp. ?-?
ISBN: 9780128093245
CID: 5418492