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21


Complex Periodontal-prosthetic Full Mouth Rehabilitation

Chapter by: Agnini, Andrea Mastrorosa; Romeo, Davide; Bral, Michael
in: Clinical & Educational Scholarship Showcase by
[New York NY : NYU College of Dentistry. NYU Academy of Distinguished Educators], 2011
pp. 16-16
ISBN: n/a
CID: 151825

Management of a patient with severe erosive lichen planus in need of an immediate complete denture: a clinical report

Rabanal, Alejandro; Bral, Michael; Goldstein, Gary
This clinical report describes the treatment of a patient in need of an immediate complete denture who presented with severe erosive lichen planus. In conjunction with an immediate complete denture, tacrolimus (0.1%) ointment, an immunosuppressive agent, was applied topically over the lesions. There was a significant reduction in the size of the lesions at the second week of treatment, allowing the patient to tolerate the prosthesis without pain, thereby improving her quality of life
PMID: 17936124
ISSN: 0022-3913
CID: 155390

Management of a patient with severe erosive lichen planus in need of an immediate complete denture: a clinical report

Rabanal, Alejandro; Bral, Michael; Goldstein, Gary
This clinical report describes the treatment of a patient in need of an immediate complete denture who presented with severe erosive lichen planus. In conjunction with an immediate complete denture, tacrolimus (0.1%) ointment, an immunosuppressive agent, was applied topically over the lesions. There was a significant reduction in the size of the lesions at the second week of treatment, allowing the patient to tolerate the prosthesis without pain, thereby improving her quality of life
PMID: 17547941
ISSN: 0022-3913
CID: 155391

Laboratory animal models in periodontology

Weinberg, M A; Bral, M
Animal models are needed to objectively evaluate the pathogenesis of human periodontal diseases and its various treatment modalities. Selection of the appropriate animal model depends on the similarity of the periodontium and the nature of the disease to that of humans. The more commonly used animal models for studying the pathogenesis of periodontal disease, use of implants and guided tissue regeneration have been dogs and nonhuman primates. Periodontal disease in rodents has not been found to be as closely related to the human varieties. Rats and hamsters are best suited for caries and calculus research. Ferrets may be a promising new model for studying periodontal disease and calculus formation. Variables unique to each animal species are manifested by a wide range of clinical and histopathological features. Different species have distinct diets, habits, life spans, tissue structures, host defense mechanisms and genetic traits. This article describes the diversity seen in animal models used to study microbiological, immunological, and clinical features of periodontal disease and its prevention and treatment
PMID: 10382571
ISSN: 0303-6979
CID: 152069

Effect of treatment on cyclosporine- and nifedipine-induced gingival enlargement: clinical and histologic results

Santi, E; Bral, M
The clinical and histologic responses to periodontal treatment of gingival enlargements, induced when cyclosporine and nifedipine were administered singly or in combination, were evaluated. A significant correlation was noted between plaque, gingivitis, and gingival overgrowth. Severity of enlargement appeared to be greater in patients on combined therapy. All treatment approaches such as scaling, root planning, gingivectomy, and periodontal flaps, and a combination of therapies, were effective in the management of gingival overgrowth up to 1 year after completion of treatment. Adjunctive use of chlorhexidine was found to be beneficial
PMID: 9558559
ISSN: 0198-7569
CID: 152610

Tetracycline and its analogues: a therapeutic paradigm in periodontal diseases

Weinberg, M A; Bral, M
This article discusses the use of tetracyclines in the clinical management of periodontal infections. A review of the drugs pharmacology, pharmacokinetics, and potential adverse effects shows that they are relatively safe if used in appropriate dosages and under controlled conditions. Current data suggest that the routine use of tetracyclines in conjunction with the treatment of periodontitis is unnecessary. However, their distinctive characteristics can be utilized in different delivery systems as an adjunctive aid to conventional treatment of juvenile and refractory forms of periodontitis
PMID: 9715369
ISSN: 1045-4411
CID: 152619

New York University: A nimble giant

Bral, Michael
ORIGINAL:0012753
ISSN: n/a
CID: 3161712

[Initial and mid-term results of coronary angioplasty in early post-infarction unstable angina]

Metzger, J P; Tabone, X; le Feuvre, C; Drobinski, G; Piolot, A; Bral, M; le Pailleur, C; Vacheron, A
The aim of this study was to assess the immediate efficacy and the medium-term risks and results of percutaneous transluminal coronary angioplasty (PTCA) in early post-infarction unstable angina. Thirty-six patients were included for a series of 248 consecutive PTCA procedures performed between December 1985 and January 1989. The average age was 56 years (range 35 to 84 years). The initial infarct was anterior (N = 16), inferior (N = 15), lateral (N = 5), without a Q wave (N = 22), transmural (N = 14) and treated by thrombolysis in 42 p. 100 of cases. The interval between initial infarction and PTCA was 16 +/- 3 days. A primary success was obtained in 33 cases (92%). One patient died of electromechanical dissociation at the beginning of the procedure. Two infarcts occurred due to acute coronary occlusions. None of the patients required emergency coronary bypass surgery. The specific risk of PTCA in early post-infarction unstable angina is acute coronary occlusion. This complication was observed in 9 patients (25%) and it required immediate repeat PTCA, associated with thrombolytic therapy in four cases. Coronary occlusion was more common in patients with transmural infarcts than in those without Q-waves (43% vs 14%; p less than 0.01) and in patients treated initially by thrombolysis compared with those not treated by thrombolysis (40% vs 15%; p less than 0.05). No fatalities or reinfarctions occurred during follow-up (average 9 +/- 8 months, range 2 to 35 months). A good clinical result was maintained in 71 per cent of patients treated by PTCA alone. Seven repeat PTCA procedures and 3 coronary bypass operations were performed during follow-up.(ABSTRACT TRUNCATED AT 250 WORDS)
PMID: 2108625
ISSN: 0003-9683
CID: 152327

Periodontal considerations for provisional restorations

Bral, M
Provisional restorations can cause alterations of tooth form, surface continuity, and the relationship of the restored tooth to the adjacent and opposing teeth as well as the periodontal tissues. As the integrity of the periodontium is of mutual interest to both the periodontist and the restorative dentist, it is important that the potential damage caused by restorative procedures and materials be avoided. Ideally, the provisional restoration should be considered an acrylic progenitor of the final restoration in all aspects except the material from which it is fabricated, its longevity, and the nuances of color and translucency. It should not be replaced by the permanent restoration until all treatment objectives have been accomplished. In an integrated multidisciplinary approach to dental care, it is logical that periodontal treatment precede final restorative procedures. The establishment and maintenance of periodontal health is clearly predicated on an intact dentogingival unit and shallow sulcular dimensions that allow accessibility for removal of plaque. Provisional restorations, whether single or multiple, must conform to and complement the healthy gingival environment if periodontal health is to be sustained. Direct and frequent communication between the periodontist and restorative dentist is a prerequisite for predictable and satisfactory results
PMID: 2668046
ISSN: 0011-8532
CID: 152356

Chemotherapeutics in periodontics

Bral, M
PMID: 2664606
ISSN: 0028-7571
CID: 152355