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Obstructive Sleep Apnea and Hypertension with Longitudinal β-Amyloid Burden and Cognitive Changes

Bubu, Omonigho M; Kaur, Sonya S; Mbah, Alfred K; Umasabor-Bubu, Ogie Q; Ramos-Cejudo, Jaime; Debure, Ludovic; Mullins, Anna E; Parekh, Ankit; Kam, Korey; Osakwe, Zainab T; Williams, Ellita T; Turner, Arlener D; Glodzik, Lidia; Rapoport, David M; Ogedegbe, Gbenga; Fieremans, Els; de Leon, Mony J; Ayappa, Indu; Jean-Louis, Girardin; Masurkar, Arjun V; Varga, Andrew W; Osorio, Ricardo S
PMID: 35550019
ISSN: 1535-4970
CID: 5213082

Poor sleep health and quality of life among caregivers of patients with prostate cancer

Thakker, Sameer; Robbins, Rebecca; Carter, Patricia; Jean-Louis, Girardin; Siu, Katherine; Sanchez Nolasco, Tatiana; Byrne, Nataliya; Orstad, Stephanie L; Myrie, Akya; Loeb, Stacy
PMCID:9349590
PMID: 35950040
ISSN: 2688-4526
CID: 5287052

Out Like a Light: Feasibility and Acceptability Study of an Audio-Based Sleep Aide for Improving Parent-Child Sleep Health

Chung, Alicia; Jin, Peng; Kamboukos, Dimitra; Robbins, Rebecca; Blanc, Judite; Jean-Louis, Girardin; Seixas, Azizi
Our study examines the acceptability and feasibility of Moshi, an audio-based mobile application, among children 3-8 years old using a parent-child dyadic approach. Our 10-day within-subject pre-post study design consisted of five nights of a normal bedtime routine and a subsequent five nights exposed to one story on the Moshi application during the intervention. Each five-night period spanned three weeknights and two weekend nights. The Short-Form Children's Sleep Habits Questionnaire (SF-CSHQ) was used to measure children's sleep at baseline and post-intervention. The PROMIS, Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index were used to assess parents' sleep. Among the 25 child-parent dyads, the mean child age was 4 (SD = 1.23) and 63% were male (n = 15). Mean parent age was 35 (SD = 5.83), 84% were female (n = 21), and 48.0% were Black (n = 12). For child-only comparisons, mean post-SF-CSHQ measures were lower compared to baseline. A trend in parent sleep is reported. This study shows the potential of an audio-based mobile sleep aid to improve sleep health in a racially diverse parent and child dyad sample.
PMID: 35954773
ISSN: 1660-4601
CID: 5287252

Development and Evaluation of the Clinical Trial HEalth Knowledge and Beliefs Scale (CHEKS)

Chung, Alicia; Donley, Tiffany; Hays, Ron D; Robbins, Rebecca; Seixas, Azizi; Jean-Louis, Girardin
Patient health literacy is vital to clinical trial engagement. Knowledge and beliefs about clinical trials may contribute to patient literacy of clinical trials, influencing engagement, enrollment and retention. We developed and assessed a survey that measures clinical trial health knowledge and beliefs, known as the Clinical trial HEalth Knowledge and belief Scale (CHEKS). The 31 survey items in CHEKS represent knowledge and beliefs about clinical trial research (n = 409) in 2017. We examined item-scale correlations for the 31 items, eliminated items with item-scale correlations less than 0.30, and then estimated internal consistency reliability for the remaining 25 items. We used the comparative fit index (CFI) and the root mean squared error of approximation (RMSEA) to evaluate model fit. The average age of the sample was 34 (SD = 15.7) and 48% female. We identified 6 of the 31 items that had item-scale correlations (corrected for overlap) lower than 0.30. Coefficient alpha for the remaining 25 items was 0.93 A one-factor categorical confirmatory factor analytic model with 16 correlated errors was not statistically significant (chi-square = 10011.994, df = 300, p < 0.001) but fit the data well (CFI = 0.95 and RMSEA = 0.07). CHEKS can assess clinical trial knowledge and beliefs.
PMCID:9315756
PMID: 35886512
ISSN: 1660-4601
CID: 5276482

DOES COPING STRATEGY PROTECT SLEEP QUALITY DURING COVID-19? AN EXAMINATION OF RACIAL, ETHNIC, CULTURAL DIFFERENCES [Meeting Abstract]

Blanc, J; Seixas, A; Small, S; Locklear, C; Dorcent, R; Auguste, E; Buysse, D; Jean-Louis, G
Introduction: Little has been done to examine within/between group predictors and mediators of race/ethnic differences in sleep health outcomes, due to COVID-19 exposure. We evaluated the effect of COVID-19 exposure on sleep quality in a multiracial/ethnic sample of New York residents.
Method(s): We conducted a cross-sectional study among adults exposed to COVID-19 across New York State from September to November of 2020. Comparisons of participant characteristics e.g., mean scores by race/ethnicity status were made using one-way ANOVA for continuous variables, and chi-square tests for categorical variables. Associations between social determinants of health (employment, location), Trauma Coping Self-Efficacy (CES-T), and sleep quality (Pittsburgh Sleep Quality Index-PSQI) were examined using multilinear regression analysis stratified by race/ethnicity.
Result(s): Of the 541 participants, 373 (68.9%) were female; mean age was 40.9 years (SD=15), 198 (36.6%) identified as Whites, 111 (20.5%) as Black, 97 (17.9%) as Hispanics, and 135(25%) identified as either Asians, Native-Americans, Pacific-Islanders. Sex was the strongest predictor [beta = 1.335; p < .05] of sleep quality, but only among Whites. Trauma Coping Self-Efficacy was negatively associated with sleep quality among Asian, Native-American, or Pacific- Islander participants [beta = -.114; p < .05 ]; Black [beta = -.099; p < .05] and White participants [beta = -0.79; p < .05] but not among Latinos/ as [beta = -.058; p = 0.71].
Conclusion(s): Coping Self-Efficacy moderated the effect of COVID-19 on sleep quality among some, but not all, racial/ethnic groups. While CSE-T scores during the first wave of COVID-19 acted as a protective factor for sleep quality among Asians, Native-Americans, and Pacific- Islanders, White and Black participants, this was not the case for Latinos/as/Hispanics residing in New York. Clinical interventions that are tailored for racial/ethnic, community and cultural needs may help to mitigate sleep problems associated with COVID-19 exposure
EMBASE:638375975
ISSN: 1550-9109
CID: 5293332

Sleep Health among Racial/Ethnic groups and Strategies to achieve Sleep Health Equity

Chapter by: Seixas, Azizi A; Briggs, Anthony Q; Blanc, Judite; Moore, Jesse; Chung, Alicia; Williams, Ellita; Rogers, April; Turner, Arlener; Jean-Louis, Girardin
in: Essentials of Sleep Medicine : A Practical Approach to Patients with Sleep by
[S.l.] : Humana Press, 2022
pp. 47-68
ISBN: 978-3-030-93738-6
CID: 5354512

Age-associated differences in sleep duration in the US population: potential effects of disease burden

Jean-Louis, Girardin; Shochat, Tamar; Youngstedt, Shawn D; Briggs, Anthony Q; Williams, Ellita T; Jin, Peng; Bubu, Omonigho Michael; Seixas, Azizi A
OBJECTIVES/OBJECTIVE:We contrasted the relative risks (RR) of short [<7 h] and long [>8 h] sleep experienced by middle-aged (45-64 years) and older (≥65 years) adults, compared with young adults (20-44 years). METHODS:We utilized NHANES data (2005-2016), capturing sociodemographic, socioeconomic, and health-related data among US adults. RESULTS:The Relative Risk (RR) of short sleep between young and middle-aged adults did not differ [RR = 1.02, NS]. However, the RR of short sleep was significantly reduced among older participants [RR = 0.81, p < 0.01]. Middle-aged adults had significantly lower RR of long sleep [RR = 0.80, p < 0.01], whereas older adults had significantly greater RR of long sleep [RR = 1.41, p < 0.01]. Compared with young adults, older adults with or without increased disease burden had significantly lower RR of short sleep [RR = 0.81, p < 0.01 and RR = 0.80, p < 0.01], respectively. However, for middle-aged adults, the RR of short sleep did not differ whether they reported a greater disease burden. Relative to young adults, older adults with or without disease burden had higher RRs of long sleep [RR = 1.39, p < 0.01] and [RR = 1.45, p < 0.01], respectively. For middle-aged adults without disease burden, the RR of long sleep was lower than among young adults [RR = 0.72, p < 0.01]. CONCLUSIONS:Compared with young adults, older adults were not at increased risk for short sleep. Rather, they reported longer sleep time regardless of the presence of disease burden. Future studies should investigate longitudinal effects of aging on objective sleep time, with or without common diseases.
PMID: 34619501
ISSN: 1878-5506
CID: 5037152

Sleep Health and Longevity-Considerations for Personalizing Existing Recommendations

Jean-Louis, Girardin; Grandner, Michael A; Pandi-Perumal, Seithikurippu R
PMID: 34477856
ISSN: 2574-3805
CID: 5070332

Sleep, Classroom Behavior, and Achievement Among Children of Color in Historically Disinvested Neighborhoods

Ursache, Alexandra; Robbins, Rebecca; Chung, Alicia; Dawson-McClure, Spring; Kamboukos, Dimitra; Calzada, Esther J; Jean-Louis, Girardin; Brotman, Laurie Miller
Children of color are more likely to have poor sleep health than White children, placing them at risk for behavioral problems in the classroom and lower academic performance. Few studies, however, have utilized standardized measures of both classroom behavior and achievement. This study examined whether children's sleep (parent and teacher report) in first grade concurrently related to independent observations of classroom behavior and longitudinally predicted achievement test scores in second grade in a sample of primarily Black (86%) children (n = 572; age = 6.8) living in historically disinvested neighborhoods. Higher teacher-reported child sleepiness was associated with lower adaptive behaviors and higher problem behaviors in the classroom, and predicted lower achievement. Parent-reported bedtime resistance and disordered breathing also predicted lower achievement.
PMID: 34041742
ISSN: 1467-8624
CID: 4940582

A Systematic Review of Workplace-Based Employee Health Interventions and Their Impact on Sleep Duration Among Shift Workers

Robbins, Rebecca; Underwood, Phoenix; Jackson, Chandra L; Jean-Louis, Giradin; Madhavaram, Shreya; Kuriakose, Shiana; Vieira, Dorice; Buxton, Orfeu M
BACKGROUND/UNASSIGNED:Shift work is associated with long-term health risks. Workplace-based health interventions hold promise for improving or maintaining the health of shift workers; yet, the impact of workplace-based interventions on shift worker sleep duration has not been assessed. We conducted a systematic review of workplace interventions on shift worker sleep. METHODS/UNASSIGNED:= 6,868 records) of all studies published through May 15, 2019. Eligibility criteria included the following: (a) individuals aged ≥18 years; (b) a workplace-based employee intervention; (c) an employee population comprised predominantly of shift workers (>50%); and (d) sleep duration as a study outcome. FINDINGS/UNASSIGNED:= 7%). A majority of the studies found that a workplace-based health intervention was associated with a desirable increase in 24-hour total sleep duration (55%). The overall average increase in daily employee sleep duration achieved by interventions ranged for RCT studies from 0.34 to 0.99 hours and for non-RCT studies from 0.02 to 1.15 hours. CONCLUSIONS/APPLICATIONS TO PRACTICE/UNASSIGNED:More than half of the employee health interventions, especially yoga or mindfulness interventions, resulted in a desirable increase in sleep duration. Workplaces hold promise as an avenue? for delivering programs and policies that aim to improve sleep duration among shift workers.
PMID: 34284682
ISSN: 2165-0969
CID: 4979632