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The use of botulinum toxin for oral-ocular synkinesis in facial paralysis
Saeedi, Arman; Varelas, Antonios N.; von Sneidern, Manuela; Lee, Judy W.
Oral-ocular synkinesis is a common, uncomfortable, and disfiguring sequela of facial nerve palsy. Despite widespread use of chemodenervation as a non-surgical intervention, limited literature exists on optimal dosage and administration techniques in these patients. This study aims to describe a reliable chemodenervation injection technique and report objective measurements and subjective satisfaction outcomes. Prospective pre-post interventional study where new, consecutive patients with previously untreated oral-ocular synkinesis secondary to facial nerve palsy were included. Patients completed a Synkinesis Assessment Questionnaire and standardized photographs were taken before and after botulinum toxin injections. Palpebral fissure symmetry was measured from photographs, with the unaffected side functioning as the control. Sixteen patients were included in the prospective study. Mean age was 48 years old and 56% male. Botulinum toxin was injected into the upper and lower medial preseptal, upper and lower lateral pretarsal, and lateral orbital orbicularis oculi (10-13 units). Standardized photographic comparison demonstrated significant improvement in palpebral fissure height with smile (p < 0.01) and lip pucker (p < 0.01). Relevant items on the Synkinesis Assessment Questionnaire also significantly improved (p < 0.01). This reliable botulinum toxin injection technique for oral-ocular synkinesis demonstrated significant improvement in subjective quality of life metrics and objective palpebral fissure height during both smile and pucker.
SCOPUS:85188739814
ISSN: 1043-1810
CID: 5693202
Complications of Nasal Tip Stabilizing Grafts with Autologous Versus Irradiated Homologous Costal Cartilage in Septorhinoplasty: A Systematic Review
Kowalski, Haley R; von Sneidern, Manuela; Wang, Ronald S; Laynor, Gregory; Lee, Judy W
PMID: 38669105
ISSN: 2689-3622
CID: 5755962
Reanimation of the Lower Lip with the Anterior Belly of Digastric Transfer: A Systematic Review
Varelas, Antonios N; Bhatt, Nupur; Varelas, Eleni A; Franco, Alexa; Lee, Judy W; Eytan, Danielle F
PMID: 38350142
ISSN: 2689-3622
CID: 5635692
Facial Reanimation After Intratemporal Facial Nerve Schwannoma Resection: A Systematic Review
Varelas, Antonios N; Varelas, Eleni A; Kay-Rivest, Emily; Eytan, Danielle F; Friedmann, David R; Lee, Judy W
PMID: 38150513
ISSN: 2689-3622
CID: 5623202
Deformity, etiology, solution, sequence (DESS): Facial analysis in rhinoplasty
Frants, Anna; Varelas, Antonios N; Franco, Alexa M; White, W Matthew; Constantinides, Minas S; Miller, Philip J; Lee, Judy W
PURPOSE/OBJECTIVE:Rhinoplasty is amongst the most challenging surgeries to perfect and can take decades. This process begins during residency; however, residents often have limited exposure to rhinoplasty during their training and lack a standardized method for systematically analyzing and formulating a surgical plan. The DESS (Deformity, Etiology, Solution, Sequence) is a novel educational format for residents that serves to increase their pre-operative comfort with the surgical evaluation and intraoperative planning for a rhinoplasty. MATERIALS AND METHODS/METHODS:A qualitative study performed at a tertiary academic institution with an otolaryngology residency program evaluating three consecutive residency classes comprised of four residents per class. A 9-item questionnaire was distributed to measure change in resident comfort after utilizing the DESS during their facial plastics rotation. Questionnaire responses highlighted resident comfort with facial nasal analysis, identifying deformities, suggesting surgical maneuvers, and synthesizing a comprehensive surgical plan. RESULTS:Ten of the twelve residents surveyed responded. Of those that responded, comfort in facial nasal analysis, identification of common nasal deformities, surgical planning, and development of an overall surgical plan were significantly improved after completion of the facial plastic rotation. These residents largely attributed their success to the systematic educational format, with an average score of 4.8/5.0 (SD 0.42). CONCLUSION/CONCLUSIONS:While rhinoplasty is a challenging artform to master, systematic approaches to analysis and operative planning are vital for teaching and guiding residents. Through this novel methodology, residents display significant improvement in their comfort with facial nasal analysis and overall surgical preparation.
PMID: 37952257
ISSN: 1532-818x
CID: 5610802
Gender Differences in Compensation, Mentorship, and Work-Life Balance within Facial Plastic Surgery
Lafer, Marissa P; Frants, Anna; Zhang, Yan; Wang, Binhuan; Lee, Judy W
OBJECTIVES/OBJECTIVE:Our objective was to identify gender differences in work-life balance, professional advancement, workload, salary, and career satisfaction among facial plastic and reconstructive surgeons. STUDY DESIGN/METHODS:Cross-Sectional Survey METHODS: American Academy of Facial Plastic and Reconstructive Surgery (AAFPRS) members were invited by email to respond to a confidential 25-question online survey. The survey had a response rate of 12%. There were a total of 139 participants; 23 participants were in training and 116 were either board-eligible or board-certified facial plastic surgeons. Collected variables included general demographics, personal life, academic involvement, career development, workload, and career satisfaction. RESULTS:Forty percent of participants were female. Fifty-nine percent of female participants were 25-35 years old compared with 15% of male participants. The majority of male participants were over 45 years old (63%) while only 19% of female participants fell into this age category (P < .0001). Women were more likely to be in a relationship with a physician (35% vs. 19%) or non-physician full-time professional (55% vs. 31%). The vast majority of men had children (89%) while only half of women (52%) had children. On average, women with children had fewer children than men (P < .0001). No gender difference was seen with respect to working full versus part-time (P = .81). Participants were equally satisfied with a surgical career regardless of gender. CONCLUSION/CONCLUSIONS:Although significant progress has already been made towards closing the gender gap, gender disparities remain both professionally and personally for facial plastic surgeons. With an increasing number of women in medicine, we should continue to strive to close the gender gap. LEVEL OF EVIDENCE/METHODS:4 Laryngoscope, 2020.
PMID: 32804423
ISSN: 1531-4995
CID: 4615072
Prospective Randomized Trial Comparing Opioids versus Nonsteroidal Antiinflammatory Drugs for Postoperative Analgesia in Outpatient Rhinoplasty
Frants, Anna; Garber, David; Lafer, Marissa P; Gordon, Steven A; Markey, Jeffrey D; Zhang, Yan; Wang, Binhuan; Lee, Judy W
BACKGROUND:The misuse and abuse of opioids, including overprescription, has led to the current opioid epidemic and national crisis. There is a national effort to eliminate the unnecessary prescription of opioids for analgesia. METHODS:Seventy patients were randomized to receive postoperative analgesia with either 5 mg hydrocodone with 325 mg acetaminophen (opioid control group) or 400 mg of ibuprofen [nonsteroidal antiinflammatory drug (NSAID) experimental group]. Pain levels were assessed on postoperative days 1, 2, and 7. Outcome measures included numeric pain rating scores and assessments of frequency and amount of analgesic used. RESULTS:There was no significant difference in gender (p = 0.81) or age (p = 0.61) between groups. On postoperative day 0, the NSAID group (mean ± SD, 2.54 ± 1.57) was found to be noninferior to the opioid group (mean ± SD, 3.14 ± 1.75; p = 0.003). On postoperative day 1, the NSAID group showed a lower mean pain score (mean ± SD, 1.84 ± 1.29) than the opioid group (mean ± SD, 2.46 ± 1.90; p = 0.01). However, on postoperative day 7, the difference in pain scores between the NSAID (mean ± SD, 3.29 ± 2.14) and opioid (mean ± SD, 3.14 ± 2.12; p = 0.17) groups lost statistical significance. There was no significant difference in mean day of medication cessation between the NSAID (mean ± SD, 4.73 ± 1.57) and opioid (mean ± SD, 4.28 ± 2.23; p = 0.26) groups. Seventy-six percent of patients who were prescribed opioids took fewer than eight tablets. Five patients escalated from NSAIDs to opioids. There were no adverse effects related to NSAID use. CONCLUSIONS:NSAIDs are an acceptable and safe alternative to opioids for postoperative analgesia in rhinoplasty and potentially lead to better overall pain control in some patients. Significantly reducing or eliminating opioid prescriptions may be considered in light of the current opioid epidemic. CLINICAL QUESTION/LEVEL OF EVIDENCE/METHODS:Therapeutic, II.
PMID: 33370050
ISSN: 1529-4242
CID: 4731622
Reconstruction of the Forehead and Scalp
Bradford, Benjamin D; Lee, Judy W
Tissue inelasticity and the hair-bearing nature of the scalp and forehead pose unique challenges during reconstruction. A thorough understanding of the surgical anatomy of the scalp and forehead is paramount for optimal reconstructive outcomes. Primary wound closure is usually preferred over secondary intention healing and skin grafting. Use of dermal alternatives and tissue expansion are adjunctive therapies to facilitate scalp wound closure. Local skin and soft tissue flaps are commonly used for most small to medium defects; however, microsurgical free tissue transfer can be considered for large full-thickness skin defects of the forehead and scalp.
PMID: 30420075
ISSN: 1558-1926
CID: 3458402
Skin necrosis in a magnet-based bone-conduction implant
Gallant, Sara; Lee, Judy; Jethanamest, Daniel
PMID: 29236264
ISSN: 1942-7522
CID: 2844222
Age-related histologic changes in human nasal cartilage
Lee, Judy W; McHugh, Jonathan; Kim, Jennifer C; Baker, Shan R; Moyer, Jeffrey S
IMPORTANCE: Understanding age-related changes is important when considering cartilage-based implants or grafts during rhinoplasty and nasal reconstructive surgery. OBJECTIVE: To characterize the cellular and architectural changes in human nasal cartilage with aging. DESIGN: Laboratory study. PARTICIPANTS: Nasal septal cartilage was harvested from 50 consecutive patients undergoing septoplasty, rhinoplasty, or septorhinoplasty. INTERVENTION: Cartilage specimens were stained with hematoxylin-eosin (H&E) and safranin O for cartilage. MAIN OUTCOME MEASURES: A modified Mankin histologic grading scale was used to analyze each cartilage sample for H&E findings and safranin O staining. Higher H&E scores indicated more degenerative changes, while higher safranin O scores indicated reductions in proteoglycan content within the cartilage matrix, representing decreased active chondrocyte activity. Correlation between H&E and safranin O scores and patient age was determined. RESULTS: There was positive correlation between safranin O staining scores and age, with higher scores seen with advancing age (P = .01). A linear regression best-fit equation was determined to calculate a potential safranin O staining score for a given age. CONCLUSIONS AND RELEVANCE: We have quantitatively determined that advancing age is positively correlated with reductions in cartilage proteoglycan content and active cartilage growth. This finding not only enhances our current understanding of the natural changes that occur in cartilage with aging but may also affect surgical decision making when cartilage grafting is considered during functional, reconstructive, and aesthetic rhinoplasty. LEVEL OF EVIDENCE: NR.
PMID: 23558968
ISSN: 2168-6076
CID: 1464892