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Preparing for Ebola Virus Disease in West African countries not yet affected: perspectives from Ghanaian health professionals

Nyarko, Yaw; Goldfrank, Lewis; Ogedegbe, Gbenga; Soghoian, Sari; de-Graft Aikins, Ama
BACKGROUND: The current Ebola Virus Disease (EVD) epidemic has ravaged the social fabric of three West African countries and affected people worldwide. We report key themes from an agenda-setting, multi-disciplinary roundtable convened to examine experiences and implications for health systems in Ghana, a nation without cases but where risk for spread is high and the economic, social and political impact of the impending threat is already felt. DISCUSSION: Participants' personal stories and the broader debates to define fundamental issues and opportunities for preparedness focused on three inter-related themes. First, the dangers of the fear response itself were highlighted as a threat to the integrity and continuity of quality care. Second, healthcare workers' fears were compounded by a demonstrable lack of societal and personal protections for infection prevention and control in communities and healthcare facilities, as evidenced by an ongoing cholera epidemic affecting over 20,000 patients in the capital Accra alone since June 2014. Third, a lack of coherent messaging and direction from leadership seems to have limited coordination and reinforced a level of mistrust in the government's ability and commitment to mobilize an adequate response. Initial recommendations include urgent investment in the needed supplies and infrastructure for basic, routine infection control in communities and healthcare facilities, provision of assurances with securities for frontline healthcare workers, establishment of a multi-sector, "all-hazards" outbreak surveillance system, and engaging directly with key community groups to co-produce contextually relevant educational messages that will help decrease stigma, fear, and the demoralizing perception that the disease defies remedy or control. The EVD epidemic provides an unprecedented opportunity for West African countries not yet affected by EVD cases to make progress on tackling long-standing health systems weaknesses. This roundtable discussion emphasized the urgent need to strengthen capacity for infection control, occupational health and safety, and leadership coordination. Significant commitment is needed to raise standards of hygiene in communities and health facilities, build mechanisms for collaboration across sectors, and engage community stakeholders in creating the needed solutions. It would be both devastating and irresponsible to waste the opportunity.
PMCID:4363361
PMID: 25885772
ISSN: 1744-8603
CID: 1645452

International perspectives on medical toxicology

Chapter by: Soghoian, Sari
in: Goldfrank's toxicologic emergencies by Hoffman, Robert S; Howland, Mary Ann; Lewin, Neal A; Nelson, Lewis; Goldfrank, Lewis R; Flomenbaum, Neal [Eds]
New York : McGraw-Hill Education, [2015]
pp. ?-?
ISBN: 0071801847
CID: 2505802

Manganese

Chapter by: Soghoian, Sari
in: Goldfrank's toxicologic emergencies by Hoffman, Robert S; Howland, Mary Ann; Lewin, Neal A; Nelson, Lewis; Goldfrank, Lewis R; Flomenbaum, Neal [Eds]
New York : McGraw-Hill Education, [2015]
pp. ?-?
ISBN: 0071801847
CID: 2505792

Nicotine

Chapter by: Soghoian, Sari
in: Goldfrank's toxicologic emergencies by Hoffman, Robert S; Howland, Mary Ann; Lewin, Neal A; Nelson, Lewis; Goldfrank, Lewis R; Flomenbaum, Neal [Eds]
New York : McGraw-Hill Education, [2015]
pp. ?-?
ISBN: 0071801847
CID: 2505782

Essentials for emergency care: Lessons from an inventory assessment of an emergency centre in Sub-Saharan Africa

Osei, K M; Hamilton, B; Freeman, F B; Nunoo, N; Torrey, S B; Soghoian, S
Introduction: The World Health Organization (WHO) has published lists of essential equipment and supplies for delivering emergency care in resource-limited settings. The objective of this study was to assess material resources available for adult emergency care at a major academic tertiary care referral centre in Accra, Ghana, to determine quality improvement needs.
Method(s): A spot inventory of emergency centre equipment and supplies was conducted in Korle-Bu Teaching Hospital (KBTH) and compared to the WHO essential emergency equipment list released in 2006.
Result(s): Most items considered essential were available at the time of inventory. Notable exceptions included: equipment and supplies for healthcare provider safety and infection control, advanced airway management, and ophthalmologic or gynaecological examinations. Several additional items, such as glucometers and pulse oximeters, were available and often used for patient care.
Conclusion(s): Beyond pointing out specific material resource deficiencies at the Surgical Medical Emergency (SME) centre, our inventory assessment indicated a need to develop better implementation strategies for infection control policies, to collaborate with other departments on coordination of patient care, and to set a research agenda to develop emergency and acute care protocols that are both effective and sustainable in our setting. Equipment and supplies are essential elements of emergency preparedness that must be both available and 'ready-to-hand'. Consequently, key factors in determining readiness to provide quality emergency care include supplychain, healthcare financing, functionality of systems, and a coordinated institutional vision. Lessons learnt may be useful for others facing similar challenges to emergency medicine development.
Copyright
EMBASE:602103458
ISSN: 2211-419x
CID: 4315712

Native Medicines and Cardiovascular Toxicity

Chapter by: Bhalla, A; Thirumalaikolundusubramanian, P; Fung, J; Cordero-Schmidt, G; Soghoian, S; Sikka, VK; Dhindsa, HS; Singh, S
in: Heart and Toxins by
pp. 175-202
ISBN: 9780124165991
CID: 1842982

mHealth in Sub-Saharan Africa

Betjeman, Thomas J; Soghoian, Samara E; Foran, Mark P
Mobile phone penetration rates have reached 63% in sub-Saharan Africa (SSA) and are projected to pass 70% by 2013. In SSA, millions of people who never used traditional landlines now use mobile phones on a regular basis. Mobile health, or mHealth, is the utilization of short messaging service (SMS), wireless data transmission, voice calling, and smartphone applications to transmit health-related information or direct care. This systematic review analyzes and summarizes key articles from the current body of peer-reviewed literature on PubMed on the topic of mHealth in SSA. Studies included in the review demonstrate that mHealth can improve and reduce the cost of patient monitoring, medication adherence, and healthcare worker communication, especially in rural areas. mHealth has also shown initial promise in emergency and disaster response, helping standardize, store, analyze, and share patient information. Challenges for mHealth implementation in SSA include operating costs, knowledge, infrastructure, and policy among many others. Further studies of the effectiveness of mHealth interventions are being hindered by similar factors as well as a lack of standardization in study design. Overall, the current evidence is not strong enough to warrant large-scale implementation of existing mHealth interventions in SSA, but rapid progress of both infrastructure and mHealth-related research in the region could justify scale-up of the most promising programs in the near future.
PMCID:3867872
PMID: 24369460
ISSN: 1687-6415
CID: 781552

Environmental Testing for Lead in Accra, Ghana [Meeting Abstract]

Mysliwiec, R; Altman, N; Moye, E; Youssouf, A; Hoffman, RS; Soghoian, S
ISI:000302024600080
ISSN: 1556-3650
CID: 2786482

IMPACT OF A COMMUNITY EDUCATION PROGRAM ON POISON CENTER UTILIZATION IN GHANA [Meeting Abstract]

Soghoian, Sari; Nyadedzor, Caesar; Clarke, Edith; Vohra, Rishi; Caces, Phyllis; Goldfrank, Lewis R
ISI:000293692600294
ISSN: 1556-3650
CID: 2506502

Unintentional i.v. injection of barium sulfate in a child

Soghoian, Samara; Hoffman, Robert S; Nelson, Lewis
PURPOSE: A case of barium sulfate injection into the superior vena cava during an upper gastrointestinal series (UGIS) in which the patient's central venous line (CVL) was mistaken for her gastrostomy tube is reported. SUMMARY: A 17-month-old girl was brought to the fluoroscopy suite to undergo a UGIS with barium sulfate contrast. Her medical history included premature birth and short-gut syndrome after a bowel resection for necrotizing enterocolitis and gastroschisis. She had been treated for multiple bouts of sepsis and was currently receiving antibiotic therapy at home via a CVL. She was admitted to the hospital for replacement of her CVL. In the hospital, the patient developed a diarrheal illness with projectile vomiting, prompting the UGIS. In the fluoroscopy suite, approximately 3 mL of barium sulfate was injected into the patient's CVL, which was misidentified as her gastrostomy tube. The error was recognized when the first video fluoroscopic image revealed barium in the patient's right atrium, and 10 mL of blood containing a thick, chalky, whitish-pink suspension was immediately aspirated from the CVL. Peripheral venous access was established, and the CVL was removed. The patient vomited three times and developed rigors 30 minutes later. That evening, she developed a fever, which was treated with acetaminophen and a course of broad-spectrum antibiotics. Subsequent radiographs of the patient's chest failed to show any residual barium, and no respiratory distress developed. The patient was discharged in stable condition four days later. CONCLUSION: A 17-month-old girl inadvertently received barium sulfate by i.v. injection through a CVL that was mistaken for the patient's gastrostomy tube
PMID: 20410548
ISSN: 1535-2900
CID: 133788