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Exploring the Relationship Between Eating Disorders and Reproductive Health, with a Focus on Fertility, Obstetric, and Fetal Outcomes: A Narrative Review

Storto, Mara E; Bailey-Straebler, Suzanne M; Susser, Leah C
PURPOSE OF REVIEW/OBJECTIVE:Eating disorders can profoundly impact reproductive health in females, spanning from the onset of puberty through menopause. The impact is due to a variety of factors, including nutritional status, body fat percentage, and hormone regulation. Notably, fertility and pregnancy are particularly vulnerable to undernutrition and disordered eating. This narrative review provides a comprehensive summary and discussion of available literature from the past 5 years exploring the impact of eating disorders on fertility, obstetric outcomes, and fetal outcomes. RECENT FINDINGS/RESULTS:Current literature demonstrates that EDs can have a negative impact on fertility, obstetric outcomes, and fetal outcomes. Primary research and systematic reviews support associations including increased use of assisted reproductive treatment for infertility, anemia and hyperemesis during pregnancy, and preterm delivery. Associated fetal outcomes include infant low birth weight, small for gestational age, and microcephaly. EDs, when unrecognized and left untreated, can negatively impact fertility, obstetric outcomes, and fetal outcomes. It is important for providers to be aware of these associations and implement screening to identify at-risk patients, as appropriate treatment can improve reproductive outcomes.
PMID: 40131607
ISSN: 2161-3311
CID: 5815082

#BlackLivesMatter to C-L Psychiatrists: Examining Racial Bias in Clinical Management of Behavioral Emergencies in the Inpatient Medical Setting [Meeting Abstract]

Caravella, R A; Ying, P; Ackerman, M; Deutch, A; Siegel, C; Lin, Z; Vaughn, R; Madanes, S; Caroff, A; Storto, M; Polychroniou, P; Lewis, C; Kozikowski, A
Background: CL psychiatrists are uniquely positioned to combat structural racism in medicine Currently, there are no published papers examining racial bias in the management of psychiatric emergencies in the general medical hospital. Given the potential for restrictive clinical interventions that directly challenge a patient's autonomy (including intramuscular injections and restraints), our group embarked on a long-term, quality improvement project to detect and address racial bias affecting the clinical management of these psychiatric emergencies.
Method(s): Our institution has a multidisciplinary behavioral code team known as the Behavioral Emergency Response Team (BERT) that responds to behavioral emergencies throughout the medical hospital. Secondary BERT event data occurring from 2017 to 2020 was combined with demographic data from the electronic medical record. Race and ethnic data were collapsed into unique, phenotypic categories. BERT events were coded based on the most restrictive intervention utilized. Descriptive statistics were used to describe the sample and examine whether race / ethnicity correlated with BERT intervention utilized, diagnostic impression, reason for BERT activation, or recurrent BERTs.
Result(s): Our sample included 1532 BERT events representing N = 902 unique patients. The main interaction of BERT intervention by Race / Ethnic category reached statistical significance (p=0.04). Though most BERTs only required verbal de-escalation (n=419, 46.45%), 3% of BERTs (n = 29) escalated to 4-pt restraints (most restrictive intervention). Though reaching level 5 was rare, Black patients had a statistically significant higher likelihood of receiving this intervention compared with White patients (6% v 2%, p=0.027) and compared with all other non-Black patients (6% v 2%, p=0.040). Although the overall comparison for Race/Ethnicity and the diagnostic impression "Psychosis" did not reach significance (p=0.086), targeted analysis showed that Black patients were significantly more likely to have "Psychosis" listed as a contributing factor compared with White patients (p=0.009) and all other non-Black patients (p=0.016). Several other comparisons with Race / Ethnic category reached statistical significance: Age (p=0.048), and need for interpreter yes/no (p<0.001). Closer examination of the interaction of Race/Ethnicity x Need for Interpreter revealed that half of events involving Asian patients (n=22, 53.66%) and a third of events involving Hispanic patients (n=29, 30.53%) required interpreter services.
Discussion(s): This study demonstrates the feasibility of investigating racial bias in behavioral emergency management. The results of this preliminary analysis suggest multiple areas for enhanced education, self-awareness development, and programmatic improvement to target systemic racism, decrease racial bias, and improve patient care. These areas include bias in restraints use, the role of language in behavioral emergencies, and the influence of race on perception of underlying diagnosis.
Copyright
EMBASE:2019334423
ISSN: 2667-2960
CID: 5291782

CACNA1C Promotes Development of Calcific Aortic Valve Disease Through Dystrophic and Osteo/Chondrogenic Pathways [Meeting Abstract]

Matsui, Maiko; Storto, Mara; Hussain, Yasin; Gregg, Andrew M.; Pitt, Geoffrey
ISI:000529998006199
ISSN: 0009-7322
CID: 4940672