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The Sigmoid Sinus

Chapter by: Aly, Islam; Tubbs, R Shane
in: Anatomy, imaging and surgery of the intracranial dural venous sinuses by Tubbs, R Shane [Ed]
St. Louis, Missouri : Elsevier, [2020]
pp. 47-58
ISBN: 9780323653770
CID: 5496922

Internal Morphology of the Odontoid Process: Anatomic and Imaging Study with Application to C2 Fractures

Jenkins, Skyler; Bordes, Stephen; Aly, Islam; Jeyamohan, Shiveindra; Ishak, Basem; Iwanaga, Joe; Loukas, Marios; Tubbs, R Shane
OBJECTIVE:Fracture of the odontoid process is a critical injury to diagnose and often treat. The aim of this anatomic study was to present a comprehensive understanding of this part of the C2 vertebra. METHODS:We used 20 C2 vertebrae. Samples underwent imaging (computed tomography [CT] with and without three-dimensional reconstruction, micro-CT, 1.5T magnetic resonance imaging) and sagittal and coronal sectioning using a bone saw. Sectioned specimens were imaged under a digital handheld microscope, and transillumination of the bone was used to highlight its internal trabecular pattern. Three samples underwent infusion of the odontoid process with a hardening substance and were then decalcified. RESULTS:Internal trabecular patterns of the odontoid process of all specimens were discernible. In sagittal and coronal sections, trabecular patterns were highlighted with transillumination, but the patterns were much clearer using the digital microscope. Magnetic resonance imaging and CT provided the least detail of the imaging methods, but the trabecular patterns could be identified. Three-dimensional reconstruction of CT data was the preferred imaging method over magnetic resonance imaging and CT without three-dimensional reconstruction. The most distinct trabecular and cortical patterns were seen using micro-CT. Osteoporosis was seen in 2 specimens (10%). Five specimens (25%) were found to have a subdental synchondrosis. For most specimens, the trabeculae were found throughout the odontoid process. CONCLUSIONS:Improved knowledge of the anatomy, structural composition, and variations within the C2 vertebra may allow for better treatment options and patient care.
PMID: 30980977
ISSN: 1878-8769
CID: 5496902

Neovaginal Construction with Pelvic Peritoneum: Reviewing an Old Approach for a New Application

Slater, Michael W; Vinaja, Xochitl; Aly, Islam; Loukas, Marios; Terrell, Mark; Schober, Justine
Transgender reassignment surgeries have become a major topic of interest within the last decade. Although there are numerous surgical techniques for male-to-female reassignment, a physician must assess each patient's anatomy and past medical history to determine the most suitable technique. Additionally, patient preference is important. The neovaginal constructive technique most commonly used in male-to-female reassignment surgery is penile skin inversion, but various other techniques and tissues can also be used including pelvic peritoneum, buccal mucosa, and bowel. Surgical text descriptions were enhanced by creating new anatomical illustrations. Donor and recipient site anatomies, and the surgical technique leading to creation of the neovagina, are demonstrated in detail with relevant illustrations. A review of the literature concerning the anatomy, procedure development, and outcomes is presented. The pelvic peritoneum was originally used in neovaginal construction for females with vaginal agenesis as a result of MRKH syndrome. The use of this technique to create a neovagina in male-to-female transgender reassignment surgery has become appealing owing to the relative ease of the procedure, low complication rates, and overall high patient satisfaction. This technique offers a potential new choice for transgender male-to-female neovaginal construction, but further studies are needed to confirm its successful use in transgender surgery. Clin. Anat. 31:175-180, 2018. © 2017 Wiley Periodicals, Inc.
PMID: 29178543
ISSN: 1098-2353
CID: 5496892

Extraforaminal compression of the L5 nerve: An anatomical study with application to failed posterior decompressive procedures

Tubbs, R Shane; Iwanaga, Joe; Aly, Islam; Moisi, Marc D; Hanscom, David R; Chapman, Jens R; Loukas, Marios; Oskouian, Rod J
This anatomical study was performed to elucidate the pertinent foraminal and lateral L5 nerve anatomy to enhance our understanding of possible neurologic causes of failed decompression surgery. Persistent extraforaminal L5 nerve compression is a possible cause of persistent symptoms following lumbosacral surgery. The amount of extraforaminal space for the L5 ventral ramus was examined in fifty adult human skeletons (100 sides). Based on morphology, the specimens were then categorized (types I-IV) on the basis of the bony space available for the nerve at this location. Next, 25 embalmed adult cadavers (50 sides) underwent bilateral dissection of the lower lateral lumbar region. The type of bony extraforaminal outlet was documented for each cadaver on the basis of our skeletal analysis. Lastly, segments (intra- and extra-foraminal) of the L5 ventral ramus were excised and examined histologically. Types I-IV outlets were found in 43, 31, 20 and 6 skeletal sides, respectively. For cadavers, 22,15, 10 and 3 sides were found to have types I-IV bony outlets, respectively. In cadavers, all type IV outlets and 70% of the type III bony configurations adjacent to the L5 ventral ramus had signs of neural irritation/injury including vascular hyalinization and increased fibrosis distal to the intervertebral foramen. No distal segments of type I and type II outlets showed histological signs of neural compromise. Patients with symptoms referable to L5 nerve compression for whom no proximal pathology is identified could warrant investigation of the more distal extraforaminal segment of this nerve.
PMID: 28408248
ISSN: 1532-2653
CID: 5496882

To cut or not to cut, that is the question: A review of the anatomy, the technique, risks, and benefits of an episiotomy [Historical Article]

Muhleman, Mitchel Alan; Aly, Islam; Walters, Andrew; Topale, Nitsa; Tubbs, R Shane; Loukas, Marios
Childbirth can be a traumatic experience on the female body. Some techniques may be implemented to make the process smoother and decrease the potential lacerations that can occur. Episiotomies have been used by obstetricians and midwives to help make the fetal decent down the vaginal canal less turbulent. A physician must use his best judgment on when it is necessary to make this incision and what form of incision to make. Before making an incision one must understand the female external and internal anatomy and thoroughly comprehend the stages of birth to understand how and what complications can occur. Even though an episiotomy is a minor incision, it is still a surgical incision nonetheless and as with any form of surgery there are both risks and benefits that are to be considered. Nevertheless, episiotomies have proven to help ease births that are complicated by shoulder dystocia, prevent severe lacerations, and decrease the second stage of labor. The following comprehensive review provides a description of the female anatomy, as well as an extensive description of why, when, and how an episiotomy is done. Clin. Anat. 30:362-372, 2017. © 2017 Wiley Periodicals, Inc.
PMID: 28195378
ISSN: 1098-2353
CID: 5496872

Lumbar ribs: a comprehensive review

Aly, Islam; Chapman, Jens R; Oskouian, Rod J; Loukas, Marios; Tubbs, R Shane
BACKGROUND:To date, no single comprehensive review has been published regarding lumbar ribs. Therefore, the present review was conducted to better elucidate these variant anatomical structures, which can be confused with transverse process fractures or result in miscounting of spine segments for surgical procedures. METHODS:Using standard search engines, a review of lumbar ribs was performed. CONCLUSIONS:Lumbar ribs are uncommon but can be misinterpreted on imaging or cause confusion during surgery. Mutations of the FGD1 or Hox10 gene may be involved in the development of lumbar ribs. Knowledge of these structures can decrease misdiagnosis when they are present.
PMID: 26350805
ISSN: 1433-0350
CID: 5496852

The naming game: A discrepancy among the medical community

Loukas, Marios; Aly, Islam; Tubbs, R Shane; Anderson, Robert H
As anatomists we rely on the nomenclature of structures in order to describe them appropriately, particularly their orientation in respect to their surrounding. The terminology used by the anatomist to describe an organ, muscle, or nerve within the body is taught to medical students as law. Students learn to describe structures in the "anatomical position", which has been accepted in the literature since the original Latin Nomina Anatomica. They therefore familiarize themselves with the use of terms such as superior, inferior, posterior and anterior to describe all anatomical structures, except in respect of the heart. The heart is still described in the original Valentine position. As anatomists we owe it to the medical and research community to correct the nomenclature to minimize confusion, and to describe the heart properly in respect to its surrounding structures.
PMID: 26579876
ISSN: 1098-2353
CID: 5496862

Samuel von Soemmerring

Aly, Islam; Tubbs, RS; Shoja, MM; Loukas, M
ORIGINAL:0016905
ISSN: 2380-6168
CID: 5496912