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Supporting American Academy of Neurology's new clinical practice guideline on evaluation and management of insomnia in children with autism [Comment]

Rosen, Carol L; Aurora, R Nisha; Kapur, Vishesh K; Ramos, Alberto R; Rowley, James A; Troester, Matthew M; Zak, Rochelle S
Rosen CL, Aurora RN, Kapur VK, et al. Supporting American Academy of Neurology’s new clinical practice guideline on evaluation and management of insomnia in children with autism. J Clin Sleep Med. 2020;16(6):989–990.
PMID: 32125270
ISSN: 1550-9397
CID: 5400742

Sleep, Fatigue and Burnout Among Physicians: An American Academy of Sleep Medicine Position Statement

Kancherla, Binal S; Upender, Raghu; Collen, Jacob F; Rishi, Muhammad Adeel; Sullivan, Shannon S; Ahmed, Omer; Berneking, Michael; Flynn-Evans, Erin E; Peters, Brandon R; Abbasi-Feinberg, Fariha; Aurora, R Nisha; Carden, Kelly A; Kirsch, Douglas B; Kristo, David A; Malhotra, Raman K; Martin, Jennifer L; Olson, Eric J; Ramar, Kannan; Rosen, Carol L; Rowley, James A; Shelgikar, Anita V; Gurubhagavatula, Indira
None/UNASSIGNED:Physician burnout is a serious and growing threat to the medical profession and may undermine efforts to maintain a sufficient physician workforce to care for the growing and aging patient population in the U.S. Burnout involves a host of complex underlying associations and potential for risk. While prevalence is unknown, recent estimates of physician burnout are quite high, approaching 50% or more, with mid-career physicians at highest risk. Sleep deprivation due to shift-work schedules, high workload, long hours, sleep interruptions, and insufficient recovery sleep have been implicated in the genesis and perpetuation of burnout. Maladaptive attitudes regarding sleep and endurance also may increase the risk for sleep deprivation among attending physicians. While duty-hour restrictions have been instituted to protect sleep opportunity among trainees, virtually no such effort has been made for attending physicians who have completed their training or practicing physicians in non-academic settings. It is the position of the AASM that a critical need exists to evaluate the roles of sleep disruption, sleep deprivation, and circadian misalignment in physician well-being and burnout. Such evaluation may pave the way for the development of effective countermeasures that promote healthy sleep, with the goal of reducing burnout and its negative impacts such as a shrinking physician workforce, poor physician health and functional outcomes, lower quality of care, and compromised patient safety.
PMID: 32108570
ISSN: 1550-9397
CID: 4324452

Natural History of Sleep-disordered Breathing during Rapid Eye Movement Sleep. Relevance for Incident Cardiovascular Disease

Aurora, R Nisha; McGuffey, Elizabeth J; Punjabi, Naresh M
PMID: 32011165
ISSN: 2325-6621
CID: 5400722

Artificial Intelligence in Sleep Medicine: An American Academy of Sleep Medicine Position Statement

Goldstein, Cathy A; Berry, Richard B; Kent, David T; Kristo, David A; Seixas, Azizi A; Redline, Susan; Westover, M Brandon; Abbasi-Feinberg, Fariha; Aurora, R Nisha; Carden, Kelly A; Kirsch, Douglas B; Malhotra, Raman K; Martin, Jennifer L; Olson, Eric J; Ramar, Kannan; Rosen, Carol L; Rowley, James A; Shelgikar, Anita V
None/UNASSIGNED:Sleep medicine is well positioned to benefit from advances that use big data to create artificially intelligent computer programs. One obvious initial application in the sleep disorders center is the assisted (or enhanced) scoring of sleep and associated events during a polysomnogram (PSG). This position statement outlines the potential opportunities and limitations of integrating artificial intelligence (AI) into the practice of sleep medicine. Additionally, although the most apparent and immediate application of AI in our field is the assisted scoring of PSG, we propose potential clinical use cases that transcend the sleep laboratory and are expected to deepen our understanding of sleep disorders, improve patient-centered sleep care, augment day-to-day clinical operations, and increase our knowledge of the role of sleep in health at a population level.
PMID: 32022674
ISSN: 1550-9397
CID: 4300332

Repurposing the dual orexin receptor antagonist suvorexant for the treatment of opioid use disorder: why sleep on this any longer?

James, Morgan H; Fragale, Jennifer E; Aurora, R Nisha; Cooperman, Nina A; Langleben, Daniel D; Aston-Jones, Gary
PMCID:7265392
PMID: 31986520
ISSN: 1740-634x
CID: 5404982

Chronic Opioid Therapy and Sleep: An American Academy of Sleep Medicine Position Statement

Rosen, Ilene M; Aurora, R Nisha; Kirsch, Douglas B; Carden, Kelly A; Malhotra, Raman K; Ramar, Kannan; Abbasi-Feinberg, Fariha; Kristo, David A; Martin, Jennifer L; Olson, Eric J; Rosen, Carol L; Rowley, James A; Shelgikar, Anita V
There is a complex relationship among opioids, sleep and daytime function. Patients and medical providers should be aware that chronic opioid therapy can alter sleep architecture and sleep quality as well as contribute to daytime sleepiness. It is also important for medical providers to be cognizant of other adverse effects of chronic opioid use including the impact on respiratory function during sleep. Opioids are associated with several types of sleep-disordered breathing, including sleep-related hypoventilation, central sleep apnea (CSA), and obstructive sleep apnea (OSA). Appropriate screening, diagnostic testing, and treatment of opioid-associated sleep-disordered breathing can improve patients' health and quality of life. Collaboration among medical providers is encouraged to provide high quality, patient-centered care for people who are treated with chronic opioid therapy.
PMID: 31739858
ISSN: 1550-9397
CID: 5400712

Obstructive Sleep Apnea, Sleepiness, and Glycemic Control in Type 2 Diabetes

Aurora, R Nisha; Punjabi, Naresh M
STUDY OBJECTIVES:Self-reported sleepiness is common in patients with obstructive sleep apnea (OSA) and is being increasingly recognized as an effect modifier of the association between OSA and cardiovascular outcomes. However, data on whether sleepiness modifies the association between OSA and glycemic outcomes are lacking. The current study sought to characterize the association between glycemic control and sleepiness in people with OSA and type 2 diabetes. METHODS:Adults with non-insulin requiring type 2 diabetes and undiagnosed moderate to severe OSA were recruited from the community. Demographic data, Epworth Sleepiness Scale (ESS), hemoglobin A1c (HbA1c), as well a type III home sleep test were obtained. The association between self-reported sleepiness and glycemic control was examined using quantile regression. RESULTS:or in women of any BMI category. CONCLUSIONS:The association between self-reported sleepiness and glycemic control in people with type 2 diabetes and moderate to severe OSA varies a function of BMI and sex. The noted differences in association should be considered when assessing possible treatment effects of therapy for OSA on metabolic outcomes.
PMCID:6510693
PMID: 31053205
ISSN: 1550-9397
CID: 5400702

Evolution of Sleep-Disordered Breathing After Discharge in Patients with Acute Decompensated Heart Failure [Meeting Abstract]

Aurora, R. N.; Blase, A.; Benjafield, A.; O\Connor, C. M.; Punjabi, N. M.
ISI:000466771102442
ISSN: 1073-449x
CID: 5401052

SUBJECTIVE SLEEPINESS AND PREVALENT HYPERTENSION IN ADULTS WITH TYPE 2 DIABETES MELLITUS AND OBSTRUCTIVE SLEEP APNEA [Meeting Abstract]

Aurora, Rashmi N.; Punjabi, Naresh M.
ISI:000471071002057
ISSN: 0161-8105
CID: 5401062

Clinical Use of a Home Sleep Apnea Test: An Updated American Academy of Sleep Medicine Position Statement

Rosen, Ilene M; Kirsch, Douglas B; Carden, Kelly A; Malhotra, Raman K; Ramar, Kannan; Aurora, R Nisha; Kristo, David A; Martin, Jennifer L; Olson, Eric J; Rosen, Carol L; Rowley, James A; Shelgikar, Anita V
The diagnosis and effective treatment of obstructive sleep apnea (OSA) in adults is an urgent health priority. It is the position of the American Academy of Sleep Medicine (AASM) that only a medical provider can diagnose medical conditions such as OSA and primary snoring. Throughout this statement, the term "medical provider" refers to a licensed physician and any other health care professional who is licensed to practice medicine in accordance with state licensing laws and regulations. A home sleep apnea test (HSAT) is an alternative to polysomnography for the diagnosis of OSA in uncomplicated adults presenting with signs and symptoms that indicate an increased risk of moderate to severe OSA. It is also the position of the AASM that: the need for, and appropriateness of, an HSAT must be based on the patient's medical history and a face-to-face examination by a medical provider, either in person or via telemedicine; an HSAT is a medical assessment that must be ordered by a medical provider to diagnose OSA or evaluate treatment efficacy; an HSAT should not be used for general screening of asymptomatic populations; diagnosis, assessment of treatment efficacy, and treatment decisions must not be based solely on automatically scored HSAT data, which could lead to sub-optimal care that jeopardizes patient health and safety; and the raw data from the HSAT device must be reviewed and interpreted by a physician who is either board-certified in sleep medicine or overseen by a board-certified sleep medicine physician.
PMCID:6287732
PMID: 30518456
ISSN: 1550-9397
CID: 5400692