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Similar Outcomes Achieved Between Anterior and Posterior Approach Total Hip Arthroplasty Using Dual Mobility Implants

Singh, Vivek; Thomas, Jeremiah; Arraut, Jerry; Oakley, Christian T; Rozell, Joshua C; Davidovitch, Roy I; Schwarzkopf, Ran
Background:Dual mobility (DM) bearings for total hip arthroplasty (THA) have been proposed to reduce the risk of instability in high-risk patients; however, their utility in primary THA remains relatively unexplored. No previous reports have described whether surgical approach influences outcomes associated with DM implant systems. This study aims to compare patient reported outcomes and post-operative groin pain between patients undergoing anterior approach versus posterior approach following primary THA with DM implants. Methods:We retrospectively reviewed all patients who underwent primary THA and received a DM implant between 2011-2021. Patients were stratified into two cohorts based on surgical approach (anterior vs. posterior approach). Primary outcomes included the presence of substantial postoperative groin pain as well as readmission and revision rates. Demographic differences were assessed using chi-square and independent sample t-tests. Outcomes were compared using multilinear and logistic regressions. Results:Of the 495 patients identified, 55 (11%) underwent THA via the anterior approach and 440 (89%) via the posterior approach. Surgical time (100.24 vs. 109.42 minutes, p=0.070), length of stay (2.19vs.2.67 days,p=0.072), discharge disposition (p=0.151), and significant postoperative groin pain (1.8%vs.0.7%,p=0.966) did not statistically differ between the cohorts. 90-day readmission (9.1%vs.7.7%,p=0.823) and revision rate (0.0%vs.3.0%,p=0.993) did not significantly differ as well. Specifically, readmission (p=0.993) and revision (p=0.998) for instability did not significantly differ between the cohorts. We found no statistical difference in HOOS, JR (p=0.425), VR-12 PCS (p=0.718), and VR-12 MCS (p=0.257) delta score improvement from preoperative to 1-year follow-up between the two groups. Conclusion:.
PMCID:9210419
PMID: 35821937
ISSN: 1555-1377
CID: 5269192

Failure to Meet Same-Day Discharge is Not a Predictor of Adverse Outcomes

Singh, Vivek; Nduaguba, Afamefuna M; Macaulay, William; Schwarzkopf, Ran; Davidovitch, Roy I
INTRODUCTION/BACKGROUND:As more centers introduce same-day discharge (SDD) total joint arthroplasty (TJA) programs, it is vital to understand the factors associated with successful outpatient TJA and whether outcomes vary for those that failed SDD. The purpose of this study is to compare outcomes of patients that are successfully discharged home the day of surgery to those that fail-to-launch (FTL) and require a longer in-hospital stay. MATERIALS AND METHODS/METHODS:We retrospectively reviewed all patients who enrolled in our institution's SDD TJA program from 2015 to 2020. Patients were stratified into two cohorts based on whether they were successfully SDD or FTL. Outcomes of interest included discharge disposition, 90-day readmissions, 90-day revisions, surgical time, and patient-reported outcome measures (PROMs) as assessed by the FJS-12 (3 months, 1 year, and 2 years), HOOS, JR, and KOOS, JR (preoperatively, 3 months, and 1 year). Demographic differences were assessed with chi-square and Mann-Whitney U tests. Outcomes were compared using multilinear regressions, controlling for demographic differences. RESULTS:A total of 1491 patients were included. Of these, 1384 (93%) were successfully SDD while 107 (7%) FTL and required a longer length-of-stay. Patients who FTL were more likely to be non-married (p = 0.007) and ASA class III (p = 0.017) compared to those who were successfully SDD. Surgical time was significantly longer for those who FTL compared to those who were successfully SDD (100.86 vs. 83.42 min; p < 0.001). Discharge disposition (p = 0.100), 90-day readmissions (p = 0.897), 90-day revisions (p = 0.997), and all PROM scores both preoperatively and postoperatively did not significantly differ between the two cohorts. CONCLUSION/CONCLUSIONS:Our results support the notion that FTL is not a predictor of adverse outcomes as patients who FTL achieved similar outcomes as those who were successfully SDD. The findings of this study can aid orthopedic surgeons to educate their patients who wish to participate in a similar program, as well as patients that have concerns after they failed to go home on the day of surgery. LEVEL III EVIDENCE/UNASSIGNED:Retrospective Cohort Study.
PMID: 34075486
ISSN: 1434-3916
CID: 4891522

Impact of Pre-Operative Anemia Severity on Primary Total Hip Arthroplasty Outcomes

Sicat, Chelsea Sue; Muthusamy, Nishanth; Singh, Vivek; Davidovitch, Roy I; Slover, James D; Schwarzkopf, Ran
INTRODUCTION/BACKGROUND:Preoperative anemia (POA) is a significant predictor for adverse outcomes in primary total hip arthroplasty (THA). Current literature has studied POA stratified by severity. This study aims to find a threshold preoperative hemoglobin (Hb) value for increased risk of adverse outcomes in THA. METHODS:This was a retrospective analysis of primary THA patients with preoperative Hb values from 2014-2021 from an academic orthopedic specialty hospital. Demographics, surgical data, and post-operative outcomes were collected. Patients without preoperative Hb values within the electronic health record (EHR) system or values acquired >30 days preoperatively were excluded. Patients were grouped based on POA severity using WHO criteria. Secondary analysis using discrete preoperative Hb values was performed. P-values were calculated using ANOVA/Kruskal-Wallis and chi-square/Fisher's exact testing with p<0.05 considered significant. RESULTS:A total of 1,347 patients were included, 771(57.2%) patients with POA and 576(42.8%) with normal pre-operative Hb. In the POA group, 292(37.9%) were mild, 445(57.7%) moderate, and 34(4.4%) severe. Increased length of stay (LOS) was seen in moderate (3.9+4.3vs.2.4+2.1,p<0.001) and severe (5.0+3.4vs.2.4+2.1,p<0.0001) groups compared to control. The severe group had higher 90-day readmission and revision rates compared to control. Analysis by discrete Hb values showed increased LOS in Hb values <11g/dL and a greater proportion of patients with Hb values <12g/dL were discharged to skilled nursing facilities. CONCLUSION/CONCLUSIONS:Patients with preoperative Hb <12g/dL should be assessed for other risk factors that may predispose them to post-operative complications. Further investigation is warranted to develop more robust perioperative management strategies for POA patients undergoing THA.
PMID: 34998908
ISSN: 1532-8406
CID: 5118152

The Forgotten Joint Score patient-acceptable symptom state following primary total hip arthroplasty

Singh, Vivek; Bieganowski, Thomas; Huang, Shengnan; Karia, Raj; Davidovitch, Roy I; Schwarzkopf, Ran
AIMS/OBJECTIVE:The Forgotten Joint Score-12 (FJS-12) is a validated patient-reported outcome measure (PROM) tool designed to assess artificial prosthesis awareness during daily activities following total hip arthroplasty (THA). The patient-acceptable symptom state (PASS) is the minimum cut-off value that corresponds to a patient's satisfactory state-of-health. Despite the validity and reliability of the FJS-12 having been previously demonstrated, the PASS has yet to be clearly defined. This study aims to define the PASS of the FJS-12 following primary THA. METHODS:We retrospectively reviewed all patients who underwent primary elective THA from 2019 to 2020, and answered both the FJS-12 and the Hip Disability and Osteoarthritis Outcome Score, Joint Replacement (HOOS, JR) questionnaires one-year postoperatively. HOOS, JR score was used as the anchor to estimate the PASS of FJS-12. Two statistical methods were employed: the receiver operating characteristic (ROC) curve point, which maximized the Youden index; and 75th percentile of the cumulative percentage curve of patients who had the HOOS, JR score difference larger than the cut-off value. RESULTS:This study included 780 patients. The mean one-year FJS-12 score was 65.42 (SD 28.59). The mean one-year HOOS, JR score was 82.70 (SD 16.57). A high positive correlation between FJS-12 and HOOS, JR was found (r = 0.74; p<0.001), making the HOOS, JR a valid external anchor. The threshold score of the FJS-12 that maximized the sensitivity and specificity for detecting a PASS was 66.68 (area under the curve = 0.8). The cut-off score value computed with the 75th percentile approach was 92.20. CONCLUSION/CONCLUSIONS: 2022;3(4):307-313.
PMCID:9044089
PMID: 35387474
ISSN: 2633-1462
CID: 5219652

The direct anterior approach to the hip: a useful tool in experienced hands or just another approach?

Realyvasquez, John; Singh, Vivek; Shah, Akash K; Ortiz, Dionisio; Robin, Joseph X; Brash, Andrew; Kurapatti, Mark; Davidovitch, Roy I; Schwarzkopf, Ran
The direct anterior approach (DAA) to the hip was initially described in the nineteenth century and has been used sporadically for total hip arthroplasty (THA). However, recent increased interest in tissue-sparing and small incision arthroplasty has given rise to a sharp increase in the utilization of the DAA. Although some previous studies claimed that this approach results in less muscle damage and pain as well as rapid recovery, a paucity in the literature exists to conclusively support these claims. While the DAA may be comparable to other THA approaches, no evidence to date shows improved long-term outcomes for patients compared to other surgical approaches for THA. However, the advent of new surgical instruments and tables designed specifically for use with the DAA has made the approach more feasible for surgeons. In addition, the capacity to utilize fluoroscopy intraoperatively for component positioning is a valuable asset to the approach and can be of particular benefit for surgeons during their learning curve. An understanding of its limitations and challenges is vital for the safe employment of this technique. This review summarizes the pearls and pitfalls of the DAA for THA in order to improve the understanding of this surgical technique for hip replacement surgeons.
PMCID:8796471
PMID: 35236507
ISSN: 2524-7948
CID: 5174512

Can We Predict the Need for Unplanned Reoperation After Nonunion Repair?

Landes, Emma K; Konda, Sanjit R; Davidovitch, Roy; Egol, Kenneth A
OBJECTIVES/OBJECTIVE:To identify factors associated with the need for reoperations in patients treated surgically for fracture nonunion. DESIGN/METHODS:Retrospective cohort study. SETTING/METHODS:One urban Level 1 trauma center and an orthopaedic specialty hospital. PATIENTS/PARTICIPANTS/METHODS:This study included 365 patients who did not and 95 patients who did undergo a reoperation after nonunion repair. INTERVENTION/METHODS:All patients who underwent fracture nonunion repair were identified. Baseline demographic, injury, and surgical information were collected. These factors were compared between patients who did and did not require an unplanned reoperation. MAIN OUTCOME MEASUREMENTS/METHODS:An unplanned reoperation after index fracture nonunion surgery. RESULTS:When compared with patients who did not undergo a reoperation after their index fracture nonunion surgery, patients who underwent at least 1 reoperation had a greater proportion of those who sustained an open fracture, a high-energy injury, initial neurologic or vascular injuries, the need for a flap or soft tissue graft at initial treatment, and lower extremity injuries with univariate analysis. Unplanned reoperation was also associated with diagnosis of "infected" nonunion at initial nonunion surgery. Multivariate analysis confirmed initial nerve or vascular injuries and positive infection status were statistically significant predictors of a reoperation. CONCLUSIONS:Initial injury characteristics such as nerve or vascular injury at initial injury and positive infection status at the index nonunion surgery were associated with the need for a secondary surgery after nonunion repair. Appropriate care of these patients should be aimed at adjusting expectations of unplanned reoperation in the future and potentially enhanced treatment strategies. LEVEL OF EVIDENCE/METHODS:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
PMID: 34797782
ISSN: 1531-2291
CID: 5049732

"Damage Control" Fixation of Displaced Femoral Neck Fractures in High-Risk Elderly Patients: A Feasibility Case Series

Konda, Sanjit R; Dedhia, Nicket; Rettig, Samantha; Davidovitch, Roy; Ganta, Abhishek; Egol, Kenneth A
OBJECTIVES/OBJECTIVE:To assess the outcomes of patients who underwent closed reduction and percutaneous pinning (CRPP) with cannulated screws for treatment of a displaced femoral neck fracture (DFNF) as they were deemed too high risk to undergo hemiarthroplasty (HA). DESIGN/METHODS:Prospective cohort study. SETTING/METHODS:One urban academic medical center. PATIENTS/PARTICIPANTS/METHODS:Sixteen patients treated with CRPP and 32 risk-level-matched patients treated with HA. INTERVENTION/METHODS:CRPP for patients with DFNFs who were deemed too ill to undergo HA. The concept being that CRPP would aid in pain control and facilitate mobilization and if failed, the patient could return electively after medical optimization for conversion to arthroplasty. MAIN OUTCOME MEASUREMENTS/METHODS:Complications, readmissions, mortality, inpatient cost, and functional status. RESULTS:The CRPP cohort had a greater incidence of exacerbations of chronic medical conditions or new onset of acute illness and an elevated mean American Society of Anesthesiologist score. There were no differences in discharge location, length of stay, major complication rate, ambulation before discharge, or 90-day readmission rate. Patients undergoing CRPP were less likely to experience minor complications including a significantly decreased incidence of acute blood loss anemia. Three patients (18.7%) in the CRPP cohort underwent conversion to HA or THA. There was no difference in inpatient, 30-day, or 1-year mortality. CONCLUSION/CONCLUSIONS:In the acutely ill patients with DFNFs, "damage control" fixation with CRPP can be safely performed in lieu of HA to stabilize the fracture in those unable to tolerate anesthesia or the sequelae of major surgery. Patients should be followed closely to evaluate the need for secondary surgery. LEVEL OF EVIDENCE/METHODS:Therapeutic Level III. See Instructions for Authors for a complete description of Levels of Evidence.
PMID: 34369455
ISSN: 1531-2291
CID: 5074532

Robotics Versus Navigation Versus Conventional Total Hip Arthroplasty: Does the Use of Technology Yield Superior Outcomes?

Singh, Vivek; Realyvasquez, John; Simcox, Trevor; Rozell, Joshua C; Schwarzkopf, Ran; Davidovitch, Roy I
BACKGROUND:The use of technology such as navigation and robotic systems may improve the accuracy of component positioning in total hip arthroplasty (THA), but its impact on patient-reported outcome measures (PROMs) remains unclear. This study aims to elucidate the association between the use of intraoperative technology and PROMs in patients who underwent primary THA. METHODS:We retrospectively reviewed a consecutive series of patients who underwent primary THA between 2016 and 2020 and answered PROM questionnaires. Patients were separated into 3 groups depending on intraoperative technology utilization: computer-assisted navigation, robotic-assisted, or no technology (conventional) THA. Forgotten Joint Score-12 and Hip disability and Osteoarthritis Outcome Score, Joint Replacemen scores were collected at various time points. Demographic differences were assessed with chi-square and analysis of variance. Mean scores between groups were compared using univariate analysis of covariance, controlling for all significant demographic differences. RESULTS:Of the 1960 cases identified, 896 used navigation, 135 used robotics, and 929 used no technology. There were significant statistical differences in one-year Hip disability and Osteoarthritis Outcome Score, Joint Replacement scores (85.23 vs 85.95 vs 86.76, respectively; P = .014) and two-year Forgotten Joint Score-12 scores (64.72 vs 73.35 vs 74.63, respectively; P = .004) between the 3 groups. However, these differences did not exceed the mean clinically important differences. Length of stay was statistically longest for patients who underwent conventionally performed THA versus navigation and robotics (2.22 vs 1.46 vs 1.91, respectively; P < .001). Surgical time was significantly longer for cases performed using robotics versus navigation and conventionally (119.61 vs 90.35 vs 95.35, respectively; P < .001). CONCLUSION/CONCLUSIONS:Statistical differences observed between all modalities are not likely to be clinically meaningful with regard to early patient-reported outcomes. Although intraoperative use of technology may improve the accuracy of implant placement, these modalities have not yet translated into improved early reported functional outcomes. LEVEL III EVIDENCE/UNASSIGNED:Retrospective cohort.
PMID: 33773864
ISSN: 1532-8406
CID: 4830382

Real-Time Fluoroscopic Navigation Improves Acetabular Component Positioning During Direct Anterior Approach Total Hip Arthroplasty

Herrero, Christina; Lavery, Jessica A; Anoushiravani, Afshin A; Davidovitch, Roy I
We investigated whether a novel, real-time fluoroscopybased navigation system optimized component positioning and leg length in fluoroscopically aided direct anterior approach total hip arthroplasty (DAA-THA). We retrospectively reviewed 75 fluoroscopically assisted DAA-THA performed by a single surgeon: 37 procedures used the software intraoperatively to overlay anteversion, inclination, and leg length information over the existing fluoroscopic radiograph with the aim of enhancing component positioning. The control group consisted of 38 procedures from the single surgeon's patient pool who had undergone non-navigated fluoroscopic assisted DAA-THA 1 month prior to the system's trial. Our results demonstrate that the navigation group measurements were significantly closer to the target numbers with less variation. The mean difference from target value were as follows: for anteversion (control: -4.68°, navigated: -01.0°), inclination (control: -1.87°, navigated: 0.8°), and leg length discrepancy (control: -2.59°, navigated: -0.98°). In addition, surgical time was shorter in the navigation group (75.7 vs. 74 minutes; p = 0.001). The real-time feedback and calculations provided by the navigation software provided a reproducible precision for component positioning and leg length measurement during DAA-THA.
PMID: 34081883
ISSN: 2328-5273
CID: 4891862

Impact of Obesity on the Forgotten Joint Score Following Primary Total Hip Arthroplasty

Singh, Vivek; Yeroushalmi, David; Lygrisse, Katherine A; Schwarzkopf, Ran; Davidovitch, Roy I
BACKGROUND:Obesity is a growing public health concern. This study aims to identify the association of body mass index (BMI) on postoperative Forgotten Joint Score-12 (FJS-12) in patients undergoing primary total hip arthroplasty (THA). METHODS:):<30 (nonobese) and ≥30 (obese). FJS-12 scores were collected postoperatively at 3 months, 1 year, and 2 years. Demographic differences were assessed with chi-square and independent sample t-tests. Mean scores between the groups were compared using multilinear regression analysis, controlling for demographic differences. RESULTS:Of the 2130 patients included, 1378 were nonobese, and 752 were obese. Although obese patients reported lower FJS-12 scores all time periods, there were no statistical differences between the two groups at 3 months (53.61 vs 49.62;P = .689), 1 year (68.11 vs 62.45; P = .349), and 2 years (73.60 vs 65.58; P = .102). A subanalysis comparing patients who were of normal BMI (<25), overweight (25.0-29.9), and obese (≥30) followed a similar inverse trend in scores but showed no statistical differences at all postoperative time points (3m:P = .612,1y:P = .607,2y:P = .253). Mean improvement in FJS-12 scores from 3 months to 1 year (14.50 vs 12.83; P = .041), 1 year to 2 years (5.49 vs 3.13; P = .004), and from 3 months to 2 years (20.00 vs15.96; P < .001) were significantly greater for nonobese patients compared to obese patients. CONCLUSION/CONCLUSIONS:While obesity trended toward lower FJS-12 scores, the differences in scores were not statistically significant compared to nonobese patients. BMI did not influence overall FJS-12 scores; however, obese patients achieved a slightly smaller statistical improvement during the first 2 years, though this may not be clinically significant. LEVEL III EVIDENCE/UNASSIGNED:Retrospective Cohort Study.
PMID: 33160806
ISSN: 1532-8406
CID: 4664632