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Safety of epidural gravity flow technique: response [Letter]

Grant, Gilbert J; Echevarria, Ghislaine C; Agoliati, Andrew P; Lax, Jerome; Cohen, Shaul
PMID: 33234580
ISSN: 1532-8651
CID: 4735132

Epidural gravity flow technique for labor analgesia

Grant, Gilbert J; Echevarria, Ghislaine C; Agoliati, Andrew P; Lax, Jerome; Cohen, Shaul
PMID: 32071101
ISSN: 1532-8651
CID: 4313162

Patient positioning and ultrasound visualization of the sciatic nerve in the fossa by anesthesia residents Influencia de la posición en la visualización con ultrasonido del nervio ciático en la fosa poplitea por médicos en formación

Pablo Miranda, H.; Elgueta, Francisca; Echevarria, Ghislaine; Bravo, Maria Pia; De La Cuadra-Fontaine, Juan Carlos
Objective: Evaluate the effect of the patients' position in obtaining a good quality image of the sciatic nerve at the popliteal fossa by anesthesiology trainees. Methods: First and 2nd year residents of our anesthesiology program scanned de right popliteal fossa of a unique subject. The subject laid in 3 different positions (supine, lateral and prone). Before the scanning, residents reviewed a video showing basic ultrasound probe management and images of the sciatic nerve at the popliteal fossa. Time elapsed upon receiving the ultrasound probe and obtaining a good quality image was measured (at least 70% counter definition and 3 clearly identified structures within the nerve). An evaluator (blinded to the subject position) determined during real time observation the quality of the image. Residents completed a questionnaire regarding the experience lived. Results and Conclusions: 26 residents completed the study. There were no statistical differences in the overall time needed by residents to obtain a good quality image in the 3 different positions. Although 96% felt that position influenced the ability to obtain good image. From this experience residents would prefer to do an US guided popliteal block on the prone position.
SCOPUS:85079760003
ISSN: 0716-4076
CID: 4392892

Effect of Intrathecal fentanyl on secondary hyperalgesia, in patients undergoing anterior cruciate ligament repair Efecto del fentanilo intratecal en hiperlagesia secundaria posoperatoria de cirugia ligamento cruzado anterior de rodilla

De La Cuadra-Fontaine, Juan Carlos; Echevarria, Ghislaine C.; Jara, Ximena P.; De La Fuente, Natalia L.; Puga, Valentina A.; Pablo Miranda, H.
Background and Objectives: Fentanyl addition is a common practice when administering spinal anesthesia. Intrathecal fentanyl has been associated to increased postoperative pain and increase morphine consumption, but considered to be related to acute opioid tolerance. This prospective, randomized, blind study evaluates the effect of intrathecal fentanyl in the development of secondary hyperalgesia, measured with Von Frey filaments, in patients undergoing anterior cruciate ligament repair. Methods: 46 patients having anterior cruciate ligament repair, received intrathecal hyperbaric bupivacaine 13.5 mg with fentanyl 20 mcg or no fentanyl addition. Light touch pain threshold was measured with von Frey filaments before anesthesia, at 6 and 24 hours post anesthesia in the non-operated thigh and in the forearm. Visual analogue pain scores and morphine consumption were also measured at the same time. Results: Baseline thresholds to mechanical stimuli were similar in both groups. In the forearm, analysis showed a decreased threshold for the non-fentanyl group at 24 h p = 0.036. In the lower extremity, control and treatment group showed lower thresholds (secondary hyperalgesia) p = 0.002 but no difference between them p = 0.795. VAS score and morphine consumption did not differ among groups. Conclusions: Spinal fentanyl added to hyperbaric bupivacaine showed no evidence of an augmented state of hyperalgesia after ACL repair, neither by pain threshold modification nor clinical outcomes. On the contrary, at 24 h, fentanyl may have a protective effect at levels above the spinal block.
SCOPUS:85079797090
ISSN: 0716-4076
CID: 4392922

Where Does the Time Go? Understanding What Delays Emergent Gynecologic Surgical Management from the ED to the or [Meeting Abstract]

Gray, D; Mehta-Lee, S S; Echevarria, G; Schweizer, W E
INTRODUCTION: Women who present to the emergency department (ED) for gynecologic issues at our institution undergo multiple evaluative steps. We sought to understand how these steps delay indicated operative management. Time spent at each stage of an ED visit for an acute surgical presentation was investigated as part of a quality improvement project for NYU Langone Health.
METHOD(S): This retrospective, observational study quantifies time spent by patients at each evaluative stage from presentation to operating room incision time. We included females 18 years or older, presenting to the NYU Tisch Hospital ED with acute gynecologic complaints requiring surgery. Gynecology consult records from 9/1/16 to 8/29/17 were reviewed and surgical cases were identified. We defined five relevant time points for each patient: 1--initial presentation, 2--ED provider evaluation, 3--Gynecology consult, 4--time of imaging, and 5--surgical start time. We recorded time in hours, between the above evaluations.
RESULT(S): Of 1194 consults reviewed, 79 patients required urgent surgery for benign etiologies (eg, adnexal torsion, ruptured ectopic pregnancy or heavy vaginal bleeding). The median time spent from presentation to incision was 6.1 (IQR: 4.12-8.53) hours. The median time from presentation to finalization of imaging and from gynecology evaluation to incision were 0.78 (IQR: 0.35-14) and 3.3 (IQR: 1.6-54) hours, respectively.
CONCLUSION(S): This information implies that throughout an evaluation for urgent gynecologic surgery, more than 50% of the time is spent after the decision has been made to operate. Further study of this time frame may ultimately improve bed utilization and reduce delays
EMBASE:633843734
ISSN: 1873-233x
CID: 4762142

Is psychosocial stress associated with gestational weight gain?: an analysis of national PRAMS 2012-2014 results [Meeting Abstract]

Yaghoubian, Yasaman C.; Dolin, Cara D.; Echevarria, Ghislaine C.; Brubaker, Sara G.; Mehta-Lee, Shilpi S.
ISI:000454249402214
ISSN: 0002-9378
CID: 3574652

Effects of a single subanaesthetic dose of ketamine on pain and mood after laparoscopic bariatric surgery: A randomised double-blind placebo controlled study

Wang, Jing; Echevarria, Ghislaine; Doan, Lisa; Ekasumara, Nydia; Calvino, Steven; Chae, Floria; Martinez, Erik; Robinson, Eric; Cuff, Germaine; Franco, Lola; Muntyan, Igor; Kurian, Marina; Schwack, Bradley F; Bedrosian, Andrea S; Fielding, George A; Ren-Fielding, Christine J
BACKGROUND:When administered as a continuous infusion, ketamine is known to be a potent analgesic and general anaesthetic. Recent studies suggest that a single low-dose administration of ketamine can provide a long-lasting effect on mood, but its effects when given in the postoperative period have not been studied. OBJECTIVE:We hypothesised that a single low-dose administration of ketamine after bariatric surgery can improve pain and mood scores in the immediate postoperative period. DESIGN/METHODS:We performed a randomised, double-blind, placebo-controlled study to compare a single subanaesthetic dose of ketamine (0.4 mg kg) with a normal saline placebo in the postanaesthesia care unit after laparoscopic gastric bypass and gastrectomy. SETTING/METHODS:Single-centre, tertiary care hospital, October 2014 to January 2018. PATIENTS/METHODS:A total of 100 patients were randomised into the ketamine and saline groups. INTERVENTION/METHODS:Patients in the ketamine group received a single dose of ketamine infusion (0.4 mg kg) in the postanaesthesia care unit. Patients in the placebo groups received 0.9% saline. OUTCOME MEASURES/METHODS:The primary outcome was the visual analogue pain score. A secondary outcome was performance on the short-form McGill's Pain Questionnaire (SF-MPQ). RESULTS:There were no significant differences in visual analogue pain scores between groups (group-by-time interaction P = 0.966; marginal group effect P = 0.137). However, scores on the affective scale of SF-MPQ (secondary outcome) significantly decreased in the ketamine group as early as postoperative day (POD) 2 [mean difference = -2.2 (95% bootstrap CI -2.9 to 1.6), Bonferroni adjusted P < 0.001], compared with placebo group in which the scores decreased only by POD 7. Scores on the total scale of SF-MPQ for the ketamine group were smaller compared with the placebo group (P = 0.034). CONCLUSION/CONCLUSIONS:Although there was no significant difference between ketamine and placebo for the primary outcome measure, patients who received ketamine experienced statistically and clinically significant improvement in their comprehensive evaluation of pain, particularly the affective component of pain, on POD 2. However, future studies are needed to confirm the enduring effects of ketamine on the affective response to postoperative pain. CLINICAL TRIAL REGISTRATION/BACKGROUND:NCT02452060.
PMID: 30095550
ISSN: 1365-2346
CID: 3226762

Interventional procedures in children and adolescents with chronic non-cancer pain as part of a multidisciplinary pain treatment program

Vega, Eduardo; Rivera, Gonzalo; Echevarria, Ghislaine C; Prylutskyy, Zakhar; Perez, Jordi; Ingelmo, Pablo
BACKGROUND:Interventional procedures are part of multidisciplinary pain treatment programs to treat chronic non-cancer pain conditions in children and adolescents. However, the real benefit of these interventions remains unclear. AIMS/OBJECTIVE:The aim of this study was to analyze the potential benefits of the interventional procedures in children and adolescents with chronic non-cancer pain in the setting of a multidisciplinary pain treatment program. METHODS:We retrospectively reviewed the charts of 98 children and adolescents receiving 314 diagnostic or therapeutic interventional procedures. We applied the following definitions of efficacy Short-term positive therapeutic effect: block that produced a minimum of 50% reduction in pain intensity for at least 4 weeks. Long-term positive therapeutic effect: a patient with a minimum of 50% reduction in pain intensity for at least 6 months Full recovery: a patient free of pain, not taking analgesics with normal physical and role functioning 6 months after the last procedure. RESULTS:Seventy-six of 112 diagnostic blocks (68%) were associated with a 50% reduction in pain intensity for at least 4 weeks after the procedure. One hundred and sixty-six of 202 therapeutics blocks (82%) were associated with a short-term benefit. Seventy-two of 98 patients (73%) referred a 50% reduction in their pain intensity (17%) or had full recovery 6 months after the procedures (56%) and a MPTP. Psychiatric comorbidity and more advanced age were factors associated with failure to respond to interventional procedures. CONCLUSION/CONCLUSIONS:The use of interventional procedures may represent a valid therapeutic option, associated with positive clinical outcomes within a multidisciplinary program.
PMID: 30251303
ISSN: 1460-9592
CID: 3315952

Sphenopalatine Ganglion Block to Treat Shoulder Tip Pain After Thoracic Surgery: Report of 2 Cases

Grant, Gilbert J; Echevarria, Ghislaine C; Lax, Jerome; Pass, Harvey I; Oshinsky, Michael L
Shoulder tip pain may occur after thoracic surgical procedures. The pain is caused by diaphragmatic irritation and is referred to the shoulder. Shoulder tip pain is often resistant to treatment with conventional analgesics. The sphenopalatine ganglion block has been described to manage many painful conditions. We report here the first use of this block to treat shoulder tip pain in 2 thoracic surgical patients. In both patients, the block produced rapid and sustained relief of the shoulder tip pain. We suggest that sphenopalatine ganglion block be considered to treat postoperative shoulder tip pain after thoracic surgical procedures.
PMID: 29634542
ISSN: 2575-3126
CID: 3240832

Epidural Analgesia to Facilitate Breastfeeding in a Grand Multipara

Grant, Gilbert J; Agoliati, Andrew P; Echevarria, Ghislaine C; Lax, Jerome
PMID: 29986159
ISSN: 1552-5732
CID: 3192412