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Recommendations for MRI technique in the evaluation of pelvic endometriosis: consensus statement from the Society of Abdominal Radiology endometriosis disease-focused panel

Tong, Angela; VanBuren, Wendaline M; Chamié, Luciana; Feldman, Myra; Hindman, Nicole; Huang, Chenchan; Jha, Priyanka; Kilcoyne, Aoife; Laifer-Narin, Sherelle; Nicola, Refky; Poder, Liina; Sakala, Michelle; Shenoy-Bhangle, Anuradha S; Taffel, Myles T
Endometriosis is a common entity causing chronic pain and infertility in women. The gold standard method for diagnosis is diagnostic laparoscopy, which is invasive and costly. MRI has shown promise in its ability to diagnose endometriosis and its efficacy for preoperative planning. The Society of Abdominal Radiology established a Disease-Focused Panel (DFP) to improve patient care for patients with endometriosis. In this article, the DFP performs a literature review and uses its own experience to provide technical recommendations on optimizing MRI Pelvis for the evaluation of endometriosis.
PMID: 32193592
ISSN: 2366-0058
CID: 4353742

Medical management of endometriosis: what the radiologist needs to know

Hindman, Nicole; Eswar, Christopher; Huang, Kathy; Tong, Angela
The role of the radiologist in the diagnosis and management of patients with endometriosis is increasing. Improvement in MRI imaging techniques has improved detection rate of subtle manifestations of endometriosis by radiologists. Therefore, the role of imaging in the diagnosis and follow-up after treatment is also likely to increase. Knowledge of new medical management pathways used in treating patients with endometriosis-related pain is important. The knowledge of various medication regimens will allow radiologists to continue to evaluate baseline disease, and to potentially assess for imaging response/stability to these medications. This article will review the current medical therapies in use in the management of endometriosis-related pain and describe potential imaging-related findings expected with these therapies.
PMID: 32270260
ISSN: 2366-0058
CID: 4378972

One-Stop Shopping: Dual-Energy CT for the Confident Diagnosis of Adrenal Adenomas [Comment]

Hindman, Nicole M; Megibow, Alec J
PMID: 32452734
ISSN: 1527-1315
CID: 4481952

ACR Appropriateness Criteria® Chronic Liver Disease

Bashir, Mustafa R; Horowitz, Jeanne M; Kamel, Ihab R; Arif-Tiwari, Hina; Asrani, Sumeet K; Chernyak, Victoria; Goldstein, Alan; Grajo, Joseph R; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Porter, Kristin K; Solnes, Lilja Bjork; Srivastava, Pavan K; Zaheer, Atif; Carucci, Laura R
The liver fibrosis stage is the most important clinical determinate of morbidity and mortality in patients with chronic liver diseases. With newer therapies, liver fibrosis can be stabilized and possibly reversed, thus accurate diagnosis and staging of liver fibrosis are clinically important. Ultrasound, CT, and conventional MRI can be used to establish the diagnosis of advanced fibrosis/cirrhosis but have limited utility for assessing earlier stages of fibrosis. Elastography-based ultrasound and MRI techniques are more useful for assessment of precirrhotic hepatic fibrosis. In patients with advanced fibrosis at risk for hepatocellular carcinoma (HCC), ultrasound is the surveillance modality recommended by international guidelines in nearly all circumstances. However, in patients in whom ultrasound does not assess the liver well, including those with severe steatosis or obesity, multiphase CT or MRI may have a role in surveillance for HCC. Both multiphase CT and MRI can be used for continued surveillance in patients with a history of HCC, and contrast-enhanced ultrasound may have an emerging role in this setting. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 32370979
ISSN: 1558-349x
CID: 4422382

ACR Appropriateness Criteria® Pancreatic Cyst

Fábrega-Foster, Kelly; Kamel, Ihab R; Horowitz, Jeanne M; Arif-Tiwari, Hina; Bashir, Mustafa R; Chernyak, Victoria; Goldstein, Alan; Grajo, Joseph R; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Porter, Kristin K; Scheiman, James M; Solnes, Lilja Bjork; Srivastava, Pavan K; Zaheer, Atif; Carucci, Laura R
Incidental pancreatic cysts are increasingly detected on imaging studies performed for unrelated indications and may be incompletely characterized on these studies. Adequate morphological characterization is critical due to the small risk of malignant degeneration associated with neoplastic pancreatic cysts, as well as the risk of associated pancreatic adenocarcinoma. For all pancreatic cysts, both size and morphology determine management. Specifically, imaging detection of features, such as pancreatic ductal communication and presence or absence of worrisome features or high-risk stigmata, have important management implications. The recommendations in this publication determine the appropriate initial imaging study to further evaluate a pancreatic cyst that was incidentally detected on a nondedicated imaging study. The recommendations are designed to maximize the yield of diagnostic information in order to better risk-stratify pancreatic cysts and assist in guiding future management. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 32370963
ISSN: 1558-349x
CID: 4422372

MRI safety and devices: An update and expert consensus

Jabehdar Maralani, Pejman; Schieda, Nicola; Hecht, Elizabeth M; Litt, Harold; Hindman, Nicole; Heyn, Chinthaka; Davenport, Matthew S; Zaharchuk, Greg; Hess, Christopher P; Weinreb, Jeffrey
The use of magnetic resonance imaging (MRI) is increasing globally, and MRI safety issues regarding medical devices, which are constantly being developed or upgraded, represent an ongoing challenge for MRI personnel. To assist the MRI community, a panel of 10 radiologists with expertise in MRI safety from nine high-volume academic centers formed, with the objective of providing clarity on some of the MRI safety issues for the 10 most frequently questioned devices. Ten device categories were identified. The panel reviewed the literature, including key MRI safety issues regarding screening and adverse event reports, in addition to the manufacturer's Instructions For Use. Using a Delphi-inspired method, 36 practical recommendations were generated with 100% consensus that can aid the clinical MRI community. Level of Evidence: 5 Technical Efficacy Stage: 5 J. Magn. Reson. Imaging 2019.
PMID: 31566852
ISSN: 1522-2586
CID: 4256682

Small (< 4 cm) Bosniak renal cysts: association of initial fluid percentage and enhancing solid volume thresholds with future lesion behavior

Shaish, Hiram; Ahmed, Firas; Schreiber, Jessica; Hindman, Nicole M
PURPOSE/OBJECTIVE:Evaluate the fluid percentage (FP) and enhancing solid volume (SV) of small (< 4 cm) Bosniak 2F, 3 and 4 renal lesions and the association with Bosniak category at baseline and follow-up. METHODS:Hospital database was searched from 1/1/2010 to 8/3/2018 for small (< 4 cm) Bosniak 2F, 3 and 4 lesions studied with initial and follow-up C+CT/MRI. Two radiologists blindly assigned Bosniak categories to first and last available studies. One radiologist performed volumetric analysis of each lesion, calculating the FP and SV. Association with Bosniak category was explored. RESULTS:121 patients (84:37 M:F) were identified with 136 renal lesions (84, 37 and 15 Bosniak category 2F, 3 and 4) and followed for 1-12.3 years (mean 3.5 years). 87% (73/84) of 2F lesions were downgraded or remained stable. 48% (25/52) of 3/4 lesions were downgraded. Higher FP was associated with a lower Bosniak category (p value = 0.0042). Increase in FP was associated with the probability of being downgraded on follow-up (OR 1.03, p value = 0.0036), while increase in fluid volume of lesion was directly associated with change in overall lesion size among lesions that were downgraded (b-estimate = 0.03, p value = 0.0003). All Bosniak 3/4 lesions with initial SV less than 0.05 cc were downgraded. CONCLUSION/CONCLUSIONS:FP and SV are useful quantitative surrogates for Bosniak category and future behavior, respectively. Growth of small renal lesions by an increase in fluid volume and FP leads to a downgrade in Bosniak category. Initial SV less than 0.05 cc in Bosniak 3/4 lesions suggests possible future downgrade.
PMID: 31980865
ISSN: 2366-0058
CID: 4274152

Imaging Spectrum of Endometriosis (Endometriomas to Deep Infiltrative Endometriosis)

Hindman, Nicole; VanBuren, Wendaline
In this article, the authors review the optimal imaging protocols for ultrasound and MR imaging of suspected endometriosis, review the compartmental approach to dictating these examinations, discuss the diagnostic criteria for endometriosis detection by anatomic site and the differential diagnosis, review pearls and pitfalls in diagnosis, and review what the referring physician needs to know.
PMID: 32044007
ISSN: 1557-8275
CID: 4304282

ACR Appropriateness Criteria® Acute Pancreatitis

Porter, Kristin K; Zaheer, Atif; Kamel, Ihab R; Horowitz, Jeanne M; Arif-Tiwari, Hina; Bartel, Twyla B; Bashir, Mustafa R; Camacho, Marc A; Cash, Brooks D; Chernyak, Victoria; Goldstein, Alan; Grajo, Joseph R; Gupta, Samir; Hindman, Nicole M; Kamaya, Aya; McNamara, Michelle M; Carucci, Laura R
Acute pancreatitis (AP) is divided into two types: interstitial edematous and necrotizing. AP severity is classified clinically into mild, moderately severe, and severe, depending on the presence and persistence of organ failure and local or systemic complications. The revised Atlanta classification divides the clinical course of AP into an early (first week) and late phase (after first week) and the clinical phase determines the role of imaging. Imaging has a limited role in the early phase. In the early phase with typical presentations of AP, ultrasound is usually the only appropriate modality and is used for the detection of gallstones. CT and MRI are appropriate in the early phase in equivocal presentations. In the late phase (or at least 48-72 hours after presentation), CT and MRI play a primary role in the imaging of patients with AP for evaluation of etiology, complications, extent of disease, intervention, and follow-up; CT is particularly useful in patients with suspected acute hemorrhage. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel. The guideline development and revision include an extensive analysis of current medical literature from peer reviewed journals and the application of well-established methodologies (RAND/UCLA Appropriateness Method and Grading of Recommendations Assessment, Development, and Evaluation or GRADE) to rate the appropriateness of imaging and treatment procedures for specific clinical scenarios. In those instances where evidence is lacking or equivocal, expert opinion may supplement the available evidence to recommend imaging or treatment.
PMID: 31685100
ISSN: 1558-349x
CID: 4177992

How Low Can We Go?: The Very Low Limits of Iodine Detection and Quantification in Dual-Energy CT [Comment]

Hindman, Nicole M
PMID: 31237812
ISSN: 1527-1315
CID: 3963622