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Acute Aortic Occlusion and its Sequelae: Metabolic, Pathologic Etiology and Management

Hines, George L; Liu, Helen H
Acute occlusion of the abdominal aorta is a catastrophic occurrence that results in high risk of limb loss and death. The etiology has historically been either acute embolism obstructing the aortic bifurcation in 8-75% of patients, or thrombosis of existing aorta-iliac occlusive disease in 35-84% of patients. Other etiologies include thrombosis of either a previously-placed endograft or aortic graft or acute dissection. The most common symptoms are severe pain in almost 100% of patients, or lower extremity paralysis/paresis in up to 80% of patients.Evaluation in the past was by angiography, but presently, computed tomography angiography is the preferred imaging study. Treatment is dependent on the etiology and includes embolectomy, aorta femoral bypass, axillary femoral bypass and endovascular techniques. The aim of intervention is to restore flow in the shortest time period. Mortality rates vary widely from 17- 52%, amputation occurs in up to 30% of patients. Paraplegia can occur in 40% of patients, renal insufficiency in 40-70%, and visceral ischemia in 6-14%. Both mortality and morbidity are affected by the duration of ischemia and the local and systemic complications of reperfusion injury. Complications of acute aortic occlusion can be reduced by a more prompt diagnosis, rapid intervention, and a more rapid and complete reestablishment of perfusion.
PMID: 32349067
ISSN: 1538-4683
CID: 4438952

The First Woman in Cardiac Surgery: The Life and Legacy of Dr. Nina Starr-Braunwald

Hines, George L; Martinez Aguilar, Myriam
PMID: 32941263
ISSN: 1538-4683
CID: 4835182

George Reed, MD: Cardiac Surgical Pioneer and Visionary

Hines, George L
PMID: 31804287
ISSN: 1538-4683
CID: 4249992

THE BLALOCK-TAUSSIG SHUNT at 75: A Landmark Operation and a Triumph of Diversity over Prejudice

Hines, George L
PMID: 31008775
ISSN: 1538-4683
CID: 3854122

Middle Aortic Syndrome in a Child-Bearing Age Patient

Rabenstein, Andrew P; Salhab, Khaled F; Spentzouris, Georgios; Paruchuri, Vijayapraveena; Hines, George; Vintzileos, Anthony M; Schubach, Scott L
We report a rare case of a 30-year-old female who had a long-standing history of middle aortic syndrome that was being managed nonsurgically. She presented with hypertension and buttock pain with plans to become pregnant. She underwent an aortoiliac bypass.
PMCID:6794142
PMID: 31614378
ISSN: 2325-4637
CID: 4146022

Michael E. DeBakey, Surgeon, Scientist, Innovator and Administrator (1908-2008)

Hines, George L
PMID: 30365403
ISSN: 1538-4683
CID: 3497462

Frank Cole Spencer, MD-Surgeon, Innovator, and Educator [Historical Article]

Hines, George
PMID: 29608500
ISSN: 1538-4683
CID: 3497452

Adrian Kantrowitz, MD (1918-2008) and His Contributions to Cardiac Transplantation [Editorial]

Hines, George L
PMID: 28984666
ISSN: 1538-4683
CID: 3497442

Carotid Stenosis and Impaired Cognition: The Effect of Intervention

Heller, Sloane; Hines, George
There is a clear association between carotid artery stenosis and cognitive impairment. However, there is no consensus as to how to interpret this association, and what, if any, impact this connection should have on the management of carotid stenosis. A review of the relevant literature suggests that although an intervention to relieve carotid stenosis in patients without clinically significant cognitive impairment does not improve cognition, there may be a cognitive benefit with intervention for carotid stenosis in those patients with clinically significant cognitive disorders.
PMID: 28786896
ISSN: 1538-4683
CID: 3497432

Carotid Endarterectomy in Moyamoya Disease: A Case Report [Case Report]

Spentzouris, Georgios; Mulvihill, Zachary; Hines, George
We report the case of a 55-year-old female who presented with symptomatic high-grade stenosis of the right internal carotid artery, years after her diagnosis of moyamoya disease (MMD), which had been treated with extensive carotid and cerebral vascular reconstructions. A percutaneous carotid revascularization was unsuccessful, and a carotid endarterectomy with bovine patch angioplasty was subsequently performed. The presence of symptomatic atherosclerotic carotid disease in combination with MMD, with all the perioperative challenges, has not been previously described.
PMID: 27177701
ISSN: 1615-5947
CID: 3497402