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Complications of Thoracolumbar Adult Spinal Deformity Surgery

Patel, Shyam A; McDonald, Christopher L; Reid, Daniel B C; DiSilvestro, Kevin J; Daniels, Alan H; Rihn, Jeffrey A
Adult spinal deformity (ASD) is a challenging problem for spine surgeons given the high risk of complications, both medical and surgical.
PMID: 32427777
ISSN: 2329-9185
CID: 5346982

Opioid-limiting legislation associated with decreased 30-day opioid utilization following anterior cervical decompression and fusion

Reid, Daniel B C; Patel, Shyam A; Shah, Kalpit N; Shapiro, Benjamin H; Ruddell, Jack H; Akelman, Edward; Palumbo, Mark A; Daniels, Alan H
BACKGROUND CONTEXT:Since 2016, 35 of 50 US states have passed opioid-limiting laws. The impact on postoperative opioid prescribing and secondary outcomes following anterior cervical discectomy and fusion (ACDF) remains unknown. PURPOSE:To evaluate the effect of opioid-limiting regulations on postoperative opioid prescriptions, emergency department (ED) visits, unplanned readmissions, and reoperations following elective ACDF. STUDY DESIGN/SETTING:Retrospective review of prospectively-collected data. PATIENT SAMPLE:Two hundred and eleven patients (101 pre-law, 110 post-law) undergoing primary elective 1-3 level ACDF during specified pre-law (December 1st, 2015-June 30th, 2016) and post-law (June 1st, 2017-December 31st, 2017) study periods were evaluated. METHODS:Demographic, medical, surgical, clinical, and pharmacological data was collected from all patients. Total morphine milligram equivalents (MMEs) filled was compared at 30-day postoperative intervals, before and after stratification by preoperative opioid-tolerance. Thirty- and 90-day ED visit, readmission, and reoperation rates were calculated. Independent predictors of increased 30-day and chronic (>90 day) opioid utilization were evaluated. RESULTS:Demographic, medical, and surgical factors were similar pre-law versus post-law (all p>.05). Post-law, ACDF patients received fewer opioids in their first postoperative prescription (26.65 vs. 62.08 pills, p<.001; 202.23 vs. 549.18 MMEs, p<.001) and in their first 30 postoperative days (cumulative 30-day MMEs 444.14 vs. 877.87, p<.001). Furthermore, post-law reductions in cumulative 30-day MMEs were seen among both opioid-naïve (363.54 vs. 632.20 MMEs, p<.001) and opioid-tolerant (730.08 vs. 1,122.90 MMEs, p=.022) patient populations. Increased 30-day opioid utilization was associated with surgery in the pre-law period, preoperative opioid exposure, preoperative benzodiazepine exposure, and number of levels fused (all p<.05). Chronic (>90 day) opioid requirements were associated with preoperative opioid exposure (odds ratio 4.42, p<.001) but not with pre/post-law status (p>.05). Pre- and post-law patients were similar in terms of 30- or 90-day ED visits, unplanned readmissions, and reoperations (all p>.05). CONCLUSIONS:Implementation of mandatory opioid prescribing limits effectively decreased 30-day postoperative opioid utilization following ACDF without a rebound increase in prescription refills, ED visits, unplanned hospital readmissions, or reoperations for pain.
PMID: 31487559
ISSN: 1878-1632
CID: 5328852

Risk of Dislocation and Revision Following Primary Total Hip Arthroplasty in Patients With Prior Lumbar Fusion With Spinopelvic Fixation

Yang, Daniel S; McDonald, Christopher L; DiSilvestro, Kevin J; Patel, Shyam A; Li, Neill Y; Cohen, Eric M; Daniels, Alan H
BACKGROUND:The effect of spinopelvic fixation in addition to lumbar spinal fusion (LSF) on dislocation/instability and revision in patients undergoing primary total hip arthroplasty (THA) has not been reported previously. METHODS:The PearlDiver Research Program was used to identify patients aged 30 and above undergoing primary THA who received (1) THA only, (2) THA with prior single-level LSF, (3) THA with prior 2-5 level LSF, or (4) THA with prior LSF with spinopelvic fixation. The incidence of THA revision and dislocation/instability was compared through logistic regression and Chi-squared analysis. All regressions were controlled for age, gender, and Elixhauser Comorbidity Index (ECI). RESULTS:Between 2010 and 2018, 465,558 patients without history of LSF undergoing THA were examined and compared to 180 THA patients with prior spinopelvic fixation, 5,299 with prior single-level LSF, and 1,465 with prior 2-5 level LSF. At 2 years, 7.8% of THA patients with prior spinopelvic fixation, 4.7% of THA patients with prior 2-5 level LSF, 4.2% of THA patients with prior single-level LSF, and 2.2% of THA patients undergoing only THA had a dislocation event or instability (P < .0001). After controlling for length of fusion, pelvic fixation itself was associated with higher independent risk of revision (at 2 years: 2-5 level LSF + spinopelvic fixation: aHR = 3.15, 95% CI 1.77-5.61, P < .0001 vs 2-5 level LSF with no spinopelvic fixation: aOR = 1.39, 95% CI 1.10-1.76, P < .0001). CONCLUSION/CONCLUSIONS:At 2 years, spinopelvic fixation in THA patients were associated with a greater than 3.5-fold increase in hip dislocation risk compared to those without LSF, and an over 2-fold increase in THA revision risk compared to those with LSF without spinopelvic fixation. LEVEL OF EVIDENCE/METHODS:III.
PMID: 35337945
ISSN: 1532-8406
CID: 5328922

Understanding Health Economics in Hand Surgery

Li, Neill Y; Montoya, Rachel L; Patel, Shyam A; Katarincic, Julia A
Rising health care costs in the United States, besides evolving payment models that place emphasis on value instead of volume, have led to an increasing number of studies evaluating hand surgery from an economic perspective. To better understand such economics-based studies, this review provides a foundational understanding of what value entails by defining its features of quality and cost. Principles of evaluating value through cost-benefit, cost-effectiveness, and cost-utility analyses are discussed. Models of discounting and clinical decision analyses are also discussed. Understanding such concepts and their evaluation in economic analyses will provide greater insight into the economic landscape of hand surgery and improving patient care.
PMID: 36621383
ISSN: 1531-6564
CID: 5433602

Understanding Health Economics in Joint Replacement Surgery

Glasser, Jillian L; Patel, Shyam A; Li, Neill Y; Patel, Ram A; Daniels, Alan H; Antoci, Valentin
The number of arthroplasty procedures has been rising at a significant rate, contributing to a notable portion of the nation's health care spending. This growth has contributed to an increase in the number of health care economic studies in the field of adult reconstruction surgery. Although these articles are filled with important information, they can be difficult to understand without a background in business or economics. The goal of this review is to define the common terminology used in health care economic studies, assess their value and benefit in the context of total joint arthroplasty, and highlight shortcomings in the current literature. [Orthopedics. 2022;45(4):e174-e182.].
PMID: 35394379
ISSN: 1938-2367
CID: 5328932

The Impact of the COVID-19 Pandemic on the Functionality of International Surgical Volunteer Organizations

Lyons, Spencer; Xu, Amy L; Durand, Wesley M; Patel, Shyam; Oni, Julius K; Babu, Jacob M
Background/UNASSIGNED:Surgical volunteer organizations have been severely limited during the ongoing coronavirus disease pandemic. Our purpose was to identify obstacles to surgical volunteer organizations secondary to COVID-19 and their responses. Methods/UNASSIGNED:= 24). Univariate analyses were used to compare the two cohorts. Results/UNASSIGNED:= 0.02). The three leading obstacles were finances/donations (78%), fewer volunteers (38%), and inadequate personal protective equipment (30%). In response, 39% of surgical volunteer organizations developed novel E-volunteering opportunities. For support, 85% of surgical volunteer organizations suggested monetary donations, 78% promotion through social media platforms, and 54% donation of personal protective equipment. Conclusion/UNASSIGNED:The majority of surgical volunteer organizations were unable to maintain full functionality due to stressors caused by COVID-19, including limitations on finances, volunteers, and personal protective equipment.
PMCID:9019131
PMID: 35465436
ISSN: 2296-875x
CID: 5347072

Cervical disc syndromes

Patel, Shyam A; Kuris, EO
ORIGINAL:0016125
ISSN: 1541-4515
CID: 5347162

Lumbar disc syndromes

Patel, Shyam A; Kuris, EO
ORIGINAL:0016126
ISSN: 1541-4515
CID: 5347172

Spinal cord compression

Patel, Shyam A; Kuris, EO
ORIGINAL:0016127
ISSN: 1541-4515
CID: 5347182

Spinal stenosis, cervical spine

Kosinsky, L; Patel, Shyam A; Kuris, EO
ORIGINAL:0016128
ISSN: 1541-4515
CID: 5347192