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Chronic fatigue syndrome and cognitive deficit are associated with acute-phase neuropsychiatric manifestations of COVID-19: A 9-month follow-up study

Mirfazeli, Fatemeh Sadat; Sarabi-Jamab, Atiye; Pereira-Sanchez, Victor; Kordi, Alireza; Shariati, Behnam; Shariat, Seyed Vahid; Bahrami, Salar; Nohesara, Shabnam; Almasi-Dooghaee, Mostafa; Faiz, Seyed Hamid Reza
The preva lence of long-COVID symptoms is rising but it is not still possible to predict which patients will present them, and which types of symptoms they will present. We followed up 95 patients with confirmed COVID-19 for 9 months to identify and characterize long-COVID symptoms. Easy fatigability was the most common symptom (51.04%), followed by anxiety (38.54%), dyspnea (38.54%), and new-onset headache (38.54%). There was no association between COVID-19 severity in the acute phase and the number of long-COVID symptoms (F(1,93) = 0.75, p = 0.45), and cognitive function (MoCA) scores (F(1,90) = 0.073, p = 0.787) at follow-up. Being female (F(1,92) =  - 2.27, p = 0.02), having a higher number of symptoms (F(1,93) = 2.76, p = 0.0068), and experiencing constitutional neuropsychiatric symptoms (F(1,93) = 2.529, p = 0.01) in the acute phase were associated with having chronic fatigue syndrome at follow-up. Moreover, constitutional neuropsychiatric symptoms in the acute phase were associated with a lower MoCA score (F(1,93) = 10.84, p = 0.001) at follow-up. Specific clinical presentations such as constitutional neuropsychiatric symptoms in the acute phase might be predictors of debilitating long-COVID symptoms such as chronic fatigue syndrome and cognitive deficits.
PMID: 35059902
ISSN: 1590-3478
CID: 5131882

Examining Tweet Content and Engagement of Users With Tweets About Hikikomori in Japanese: Mixed Methods Study of Social Withdrawal

Pereira-Sanchez, Victor; Alvarez-Mon, Miguel Angel; Horinouchi, Toru; Kawagishi, Ryo; Tan, Marcus P J; Hooker, Elizabeth R; Alvarez-Mon, Melchor; Teo, Alan R
BACKGROUND:Hikikomori is a form of severe social withdrawal that is particularly prevalent in Japan. Social media posts offer insight into public perceptions of mental health conditions and may also inform strategies to identify, engage, and support hard-to-reach patient populations such as individuals affected by hikikomori. OBJECTIVE:In this study, we seek to identify the types of content on Twitter related to hikikomori in the Japanese language and to assess Twitter users' engagement with that content. METHODS:We conducted a mixed methods analysis of a random sample of 4940 Japanese tweets from February to August 2018 using a hashtag (#hikikomori). Qualitative content analysis included examination of the text of each tweet, development of a codebook, and categorization of tweets into relevant codes. For quantitative analysis (n=4859 tweets), we used bivariate and multivariate logistic regression models, adjusted for multiple comparisons, and estimated the predicted probabilities of tweets receiving engagement (likes or retweets). RESULTS:Our content analysis identified 9 codes relevant to tweets about hikikomori: personal anecdotes, social support, marketing, advice, stigma, educational opportunities, refuge (ibasho), employment opportunities, and medicine and science. Tweets about personal anecdotes were the most common (present in 2747/4859, 56.53% of the tweets), followed by social support (902/4859, 18.56%) and marketing (624/4859, 12.84%). In the adjusted models, tweets coded as stigma had a lower predicted probability of likes (-33 percentage points, 95% CI -42 to -23 percentage points; P<.001) and retweets (-11 percentage points, 95% CI -18 to -4 percentage points; P<.001), personal anecdotes had a lower predicted probability of retweets (-8 percentage points, 95% CI -14 to -3 percentage points; P=.002), marketing had a lower predicted probability of likes (-13 percentage points, 95% CI -21 to -6 percentage points; P<.001), and social support had a higher predicted probability of retweets (+15 percentage points, 95% CI 6-24 percentage points; P=.001), compared with all tweets without each of these codes. CONCLUSIONS:Japanese tweets about hikikomori reflect a unique array of topics, many of which have not been identified in prior research and vary in their likelihood of receiving engagement. Tweets often contain personal stories of hikikomori, suggesting the potential to identify individuals with hikikomori through Twitter.
PMID: 35014971
ISSN: 1438-8871
CID: 5118592

Support the frontliners - Good initiatives during the COVID-19 pandemic for healthcare workers across the world: Is this what we really need?

Karaliuniene, Ruta; Nagendrappa, Sachin; Jatchavala, Chonnakarn; Ojeahere, Margaret Isioma; Ullah, Irfan; Bytyçi, Drita Gashi; Ogunnubi, Oluseun Peter; Cherro, Michele; Shalbafan, Mohammadreza; Noël, Camille; Gonzalez-Diaz, Jairo M.; Vadivel, Ramya; Pereira-Sanchez, Victor; Abu Slaih, Mohammad; Shoib, Sheikh; De Filippis, Renato
Healthcare workers have faced an unprecedented workload in overstretched health facilities during the COVID-19 pandemic, and we describe various initiatives to support them. Psychological, financial and peer support, accommodation and meal services, proper personal protective equipment, applause and gratitude in the community, spiritual and religious life, child care and volunteering were identified. The potential effects of the COVID-19 pandemic - permanent stress, burnout and other mental health problems among healthcare professionals - can be expected to grow. Continued monitoring is essential to bolster resilience among healthcare workers and prevent the possible consequences for their mental health.
SCOPUS:85125736632
ISSN: 2056-4740
CID: 5188562

Coronavirus outbreak from early career psychiatrists' viewpoint: What we have learned so far

de Filippis, Renato; Soler-Vidal, Joan; Pereira-Sanchez, Victor; Ojeahere, Margaret Isioma; Morimoto, Kana; Chang, Alice; Schuh Teixeira, Andre Luiz; Spadini, Alex Vicente
PURPOSE/OBJECTIVE:Since the World Health Organization declared the coronavirus outbreak a global pandemic several million cases and more than three million deaths have been already confirmed worldwide due to COVID-19. DESIGN AND METHODS/METHODS:Early Career Psychiatrists from all over the world present an overview of what happened in their own countries and what they have learned so far by this experience in everyday clinical practice. PRACTICE IMPLICATION/CONCLUSIONS:We tried to take a real time picture of this unexpected situation, drawing useful hints for now and the future.
PMID: 34061999
ISSN: 1744-6163
CID: 4891232

Internet gaming disorder in an adolescent during the COVID-19 pandemic: a case report [Case Report]

Rahmawati, Novi Agung; Setiawati, Yunias; Ardani, Gusti Ayu Indah; Zain, Ekachaeryanti; Pereira-Sanchez, Victor
The internet has become an indispensable tool in people´s daily lives during the COVID-19 pandemic. Internet and video game use are experiencing rapid growth in the youth and adult populations as a major source of entertainment. However, excessive gaming may cause addiction and negatively impact mental health, entailing low psychosocial well-being, poor social skills, and decreased academic achievement. We report the case of a 16-year-old student with a "typical" pattern of internet gaming disorder (IGD) developed during the pandemic, which improved after weeks of treatment with pharmacotherapy and psychosocial interventions. This case highlights that it is essential for the mental health professionals to know the psychopathology of IGD and multimodal approaches to treat it.
PMCID:9167486
PMID: 35721634
ISSN: 1937-8688
CID: 5277972

Effects of the Global Ecological Crisis on the Mental Health of Children and Adolescents: An International Perspective

Karaliuniene, Ruta; Campana, Anna Maria; Ori, Dorottya; de Filippis, Renato; Shoib, Sheikh; Saeed, Fahimeh; Mohammed, Muftau; Handuleh, Jibril; Ransing, Ramdas; Codati, Anita; Pinto da Costa, Mariana; Ojeahere, Margaret; Orsolini, Laura; Pereira-Sanchez, Victor
Climate change has become a global emergency, which mental health effects are increasingly being described and understood. Children and adolescents, especially those in low income countries and minority communities, are particularly vulnerable to experience the worst impacts of climate change now and in the coming decades. Our group of early career mental health clinicians and researchers in nine culturally and socioeconomic different countries across three continents initiated a global, online discussion about the effects of climate change on the mental health of children and adolescents, based on literature and our professional experience. We identified a paucity of research and psychiatric education on the topic, and a need to advance global and local efforts in this direction. We also identified three main domains of mental health impact of climate change: direct, indirect, and through physical conditions. Our work offers a preliminary, up-to-date overview of the consequences of climate change on the mental health of children and adolescents, and provides recommendations to advance policies, public health efforts, research, education, and clinical care in the emerging area of 'Climate Psychiatry'.
PMID: 35772140
ISSN: 0353-5053
CID: 5289462

Understanding and addressing COVID-19 vaccine hesitancy in low and middle income countries and in people with severe mental illness: Overview and recommendations for Latin America and the Caribbean

Faria, Clara Gitahy Falcão; de Matos, Ursula Medeiros Araujo; Llado-Medina, Liana; Pereira-Sanchez, Victor; Freire, Rafael; Nardi, Antonio Egidio
Despite the speedy development of vaccines for COVID-19, their rollout has posed a major public health challenge, as vaccine hesitancy (VH) and refusal are high. Addressing vaccine hesitancy is a multifactorial and context-dependent challenge. This perspective focuses on VH in the world region of Latin America and the Caribbean (LAC) and includes people suffering from severe mental illness, therefore covering populations and subpopulations often neglected in scientific literature. We present an overview of VH in LAC countries, discussing its global and historical context. Vaccine uptake has shown to widely vary across different subregions of LAC. Current data points to a possible correlation between societal polarization and vaccination, especially in countries going through political crises such as Brazil, Colombia, and Venezuela. Poor accessibility remains an additional important factor decreasing vaccination rollout in LAC countries and even further, in the whole Global South. Regarding patients with severe mental illness in LAC, and worldwide, it is paramount to include them in priority groups for immunization and monitor their vaccination coverage through public health indicators.
PMCID:9513790
PMID: 36177216
ISSN: 1664-0640
CID: 5334562

How to overcome barriers to publication in low- and middle-income countries: Recommendations from early career psychiatrists and researchers from around the world

El Halabi, Sarah; Abbas, Zargham; Adesokun, Fisayo; Adiukwu, Frances; Ashrafi, Agah; de Filippis, Renato; Handuleh, Jibril; Jaguga, Florence; Karaliuniene, Ruta; Kilic, Ozge; Nagendrappa, Sachin; Ojeahere, Margaret; Ogunnubi, Oluseun Peter; Ori, Dorottya; Orsolini, Laura; Pereira-Sanchez, Victor; Pinto da Costa, Mariana; Ransing, Ramdas; Shoib, Sheikh; Ullah, Irfan; Vadivel, Ramya; Vahdani, Bita; Ramalho, Rodrigo
There is an increasing movement toward international collaboration and global discussion in mental health. If provided with the right opportunities, early career psychiatrists (ECPs) and researchers in mental health can contribute meaningfully to this discussion. However, they often experience multiple barriers when attempting to add their voices via academic publications. We represent a diverse group of ECPs and researchers from all six World Health Organization regions. In this piece, we discuss these barriers, grounded in our first-hand experiences, and put forth a series of recommendations. The most potentially beneficial and immediate way forward is ensuring a much-needed mentorship and support, particularly for low- and middle-income countries. In this regard, international organizations, especially those with a particular focus on education, such as the Section on Education in Psychiatry of the World Psychiatric Association, can play a pivotal role.
PMID: 34873850
ISSN: 1758-5872
CID: 5088702

Teaching psychiatry in a low-income country during the COVID-19 pandemic: A hybrid collaborative psychiatry course

Virani, Sanya; Handuleh, Jibril I M; Pereira-Sanchez, Victor; Wolde-Giorgis, Daniel Fekadu
Amoud University in Borama is located in the self-declared state of Somaliland, in the Horn of Africa. Past conflicts and resulting economic hardship have led to a lack of local academic psychiatry faculty and resources. Amoud has been for some years partnering with voluntary faculty in the United Kingdom to teach psychiatry to its medical students through in-person "teaching missions." This was recently led by a Borama-native psychiatry resident in Ethiopia. COVID-19 added further hardships due to restrictions to travel and in-person gatherings. These challenges also created the opportunity for the development of an innovative, international, hybrid (online onsite), self-sustaining partnership model which has been successful in improving psychiatry teaching for undergraduate students in 2020-2021 and will continue in 2021-2022. An international, 'online-connected' department of psychiatry comprising a primary care physician in Somaliland, three postgraduate trainees in Ethiopia and the United States, and three senior psychiatrists in the United Kingdom developed a local faculty-led, hybrid-delivered, dynamic curriculum (bedside teaching, in person and online lecturing) that adapted to the needs, resources, faith and culture of Somaliland. While 2020-2021 has been the pilot year for the program, the overall experience has been enriching for students and faculty, leading to valuable cross-cultural conversations with impact on teaching and research. While learning about Somalilanders' and trauma, the program leads, also the authors of this article, have identified ways to harness the resilience and faith of students to bring about improvements in global mental health.
PMID: 34967115
ISSN: 1758-5872
CID: 5108262

Early career psychiatrists advocate reorientation not redeployment for COVID-19 care [Letter]

Alkasaby, Muhammad Abdullaitf; Philip, Sharad; Agrawal, Aditi; Jakhar, Jitender; Ojeahere, Margaret Isioma; Ori, Dorottya; Ransing, Ramdas; Saeed, Fahimeh; Mohammadreza, Shalbafan; Shoib, Sheikh; El Halabi, Sarah; Solerdelcoll, Mireia; Pereira-Sanchez, Victor; Pinto da Costa, Mariana
PMID: 34806442
ISSN: 1741-2854
CID: 5063322