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TB, HIV-associated TB and multidrug-resistant TB on Thailand's border with Myanmar, 2006-2007

Hemhongsa, Patjuban; Tasaneeyapan, Theerawit; Swaddiwudhipong, Witaya; Danyuttapolchai, Junya; Pisuttakoon, Kanoknart; Rienthong, Somsak; McCarthy, Kimberly; Varma, Melissa J; Whitmore, Jacqueline; Varma, Jay K
OBJECTIVE:To measure the burden and improve management of tuberculosis (TB), HIV-associated TB and MDR TB in Tak Province, Thailand, which borders Myanmar. METHODS:From September 2006 to August 2007, we collected uniform data about TB cases and enhanced human immunodeficiency virus (HIV) counselling and testing. We provided mycobacterial culture and drug-susceptibility testing in public or non-governmental organization facilities. Patients were classified by nationality and, for non-Thais, by migration status. RESULTS:Of 1662 TB cases in the 12-month period, 1087 (65%) occurred in non-Thais. Of non-Thais, 415 (38%) lived in Myanmar but crossed the border for healthcare. HIV infection was diagnosed in 18% of Thais compared with 12% of non-Thais (P < 0.01); HIV status was unknown for 22% of Thais and 27% of non-Thais (P = 0.02). Overall, multidrug-resistant (MDR) TB was diagnosed in 27 patients, 19 (70%) in non-Thais. Among TB cases never previously treated for TB, no MDR cases were diagnosed in Thais or in Myanmar refugees, but six cases were diagnosed in migrants from Myanmar. CONCLUSIONS:In Thailand, TB, HIV-associated TB and MDR TB in migrants from Myanmar are important public health problems; they need to be resolved in both the countries.
PMID: 18721186
ISSN: 1365-3156
CID: 4428692

Alternative splicing of the thrombopoietin receptor in an asymptomatic individual. [Meeting Abstract]

Varma, M; Schick, BP; Schulz, S; Barber, M; Pearlman, J; Waldman, SA
ISI:000072420300362
ISSN: 0009-9236
CID: 5373132