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An Exchange with Thomas Nagel: The Mind-Body Problem and Psychoanalysis [Editorial]
Nagel, Thomas; Erreich, Anne; Kessler, Richard J; Rand, Barry; Wakefield, Jerome
ISI:000375725800008
ISSN: 1941-2460
CID: 2503082
Feelings of worthlessness during a single complicated major depressive episode predict postremission suicide attempt
Wakefield, J C; Schmitz, M F
OBJECTIVE: To establish which symptoms of major depressive episode (MDE) predict postremission suicide attempts in complicated single-episode cases. METHOD: Using the nationally representative two-wave National Epidemiologic Survey on Alcohol and Related Conditions data set, we identified wave 1 lifetime single-episode MDE cases in which the episode remitted by the beginning of the wave 2 three-year follow-up period (N = 2791). The analytic sample was further limited to 'complicated' cases (N = 1872) known to have elevated suicide attempt rates, defined as having two or more of the following: suicidal ideation, marked role impairment, feeling worthless, psychomotor retardation, and prolonged (>6 months) duration. RESULTS: Logistic regression analyses showed that, after controlling for wave 1 suicide attempt which significantly predicted postremission suicide attempt (OR = 10.0), the additional complicated symptom 'feelings of worthlessness' during the wave 1 index episode significantly and very substantially predicted postremission suicide attempt (OR = 6.96). Neither wave 1 psychomotor retardation nor wave 1 suicidal ideation nor any of the other wave 1 depressive symptoms were significant predictors of wave 2 suicide attempt. CONCLUSION: Among depressive symptoms during an MDE, feelings of worthlessness is the only significant indicator of elevated risk of suicide attempt after the episode has remitted, beyond previous suicide attempts.
PMID: 26538107
ISSN: 1600-0447
CID: 2079712
Reply [Letter]
Wakefield, J C
PMID: 26538299
ISSN: 1600-0447
CID: 1930932
Against utility
Wakefield, Jerome C
PMCID:4780283
PMID: 26833603
ISSN: 1723-8617
CID: 1989522
Sadness or Depression? : International Perspectives on the Depression Epidemic and Its Meaning
Wakefield, Jerome C.; Demazeux, Steeves
[S.l.] : Springer Verlag, 2016
Extent: p. cm.
ISBN: 9401774218
CID: 1870302
Psychiatry's continuing expansion of depressive disorder
Chapter by: Wakefield, Jerome C; Horwitz, Allan V
in: Sadness or Depression? : International Perspectives on the Depression Epidemic and Its Meaning by Wakefield, Jerome C.; Demazeux, Steeves [Eds]
[S.l.] :Springer Verlag, 2016
pp. ?-?
ISBN: 9401774218
CID: 1901792
Diagnostic Issues and Controversies in DSM-5: Return of the False Positives Problem
Wakefield, Jerome C
The fifth revision of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) was the most controversial in the manual's history. This review selectively surveys some of the most important changes in DSM-5, including structural/organizational changes, modifications of diagnostic criteria, and newly introduced categories. It analyzes why these changes led to such heated controversies, which included objections to the revision's process, its goals, and the content of altered criteria and new categories. The central focus is on disputes concerning the false positives problem of setting a valid boundary between disorder and normal variation. Finally, this review highlights key problems and issues that currently remain unresolved and need to be addressed in the future, including systematically identifying false positive weaknesses in criteria, distinguishing risk from disorder, including context in diagnostic criteria, clarifying how to handle fuzzy boundaries, and improving the guidelines for "other specified" diagnosis. Expected final online publication date for the Annual Review of Clinical Psychology Volume 12 is March 28, 2016. Please see http://www.annualreviews.org/catalog/pubdates.aspx for revised estimates.
PMID: 26772207
ISSN: 1548-5951
CID: 1912812
The editor's dilemma: how DSM politics are turning psychiatry into a pseudoscience
Wakefield, J C
PMID: 26372298
ISSN: 1600-0447
CID: 1926452
DSM-5 substance use disorder: how conceptual missteps weakened the foundations of the addictive disorders field [Editorial]
Wakefield, J C
PMID: 25968656
ISSN: 1600-0447
CID: 1821992
Symptom data reanalysis disconfirms Parker et al.'s claim that latent class analysis identifies melancholic depression [Letter]
Wakefield, J C
PMID: 25754532
ISSN: 1600-0447
CID: 1812682