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Temporal trends and estimated lifetime attributable radiation risk of preoperative planning computed tomography for primary shoulder arthroplasty

Kalva, Swara R; Fucich, Dario; Perry, Arthur J; Lezak, Bradley; Torkieh, Joseph; Joshi, Tej; Virk, Mandeep S; Kwon, Young W; Yao, Jie J
BACKGROUND/UNASSIGNED:Advantages of preoperative planning computed tomography (CT) scans for shoulder arthroplasty (SA) are known; however, risks of ionizing radiation exposure remain unknown. We retrospectively reviewed institutional trends in utilization and estimated radiation risk of preoperative planning CT scans obtained for SA. METHODS/UNASSIGNED:From 2016 to 2024, the annual percent incidence of SA patients that received a preoperative planning CT was determined. The National Academy of Sciences Biological Effects of Ionizing Radiation VII report on lifetime attributable risk (LAR) cancer incidences and received radiation dose were utilized to estimate patient-level LAR projections for 100 patients stratified by sex, age, and cancer type. RESULTS/UNASSIGNED: = 0.78) from 53% to 66% of all SA patients. For all solid cancers, LAR (per 100,000 people) decreased as patient age increased, ranging from 73.1 to 9.6 for females and 40.7 to 31.4 for males (from the 50-59-year-old group to the 80-89 group). In the 60-69-year-old and 70-79-year-old groups, estimated thyroid and lung LARs were significantly higher in women. DISCUSSION/UNASSIGNED:Utilization of preoperative shoulder CT scans is increasing. Preoperative shoulder CT may be associated with a small but quantifiable projected cancer risk most pronounced in younger women.
PMCID:13249610
PMID: 42282944
ISSN: 1758-5732
CID: 6048832

Unstable distal clavicle fractures: Outcomes of internal fixation of clavicle and coracoclavicular stabilization

Xu, Jacquelyn J; Molokwu, Brian O; Shabbir-Hussain, Roban; Myerson, C Lucas; Kwon, Young W; Virk, Mandeep S
BACKGROUND/UNASSIGNED:This study evaluates outcomes following internal fixation of unstable distal clavicle fractures (DCFs) with or without coracoclavicular (CC) stabilization. METHODS/UNASSIGNED:A retrospective review was conducted for patients who underwent open repair of unstable DCFs at a single institution from 2017 to 2024. Fixation techniques included locking plate alone (P) or plate with CC stabilization [transcoracoid suture button (P + B), coracoid anchor (P + A)]. Collected variables included demographics, clinical details, patient-reported outcome measurement information system (PROMIS) scores, American Shoulder and Elbow Surgeons (ASES) scores, and Visual Analog Scale (VAS) Pain. RESULTS/UNASSIGNED:Seventeen patients with DCFs (17 shoulders;11 males, 6 females; mean age 45 [23-78] years) were followed for an average of 32.0 (3.4-69.3) months. Fixation groups included P (6), P + B (8), and P + A (3). Neer types included IIA (4), IIB (6), and V (7). Mean outcome scores were PROMIS upper extremity 49.2 ± 10.5, pain interference 47.0 ± 7.2, pain intensity 39.3 ± 7.0, ASES 89.3 ± 14.3, and VAS 1.5 ± 2.2. Three patients (18%) experienced postoperative issues: plate prominence (2) and shoulder stiffness (1); none required reoperation. DISCUSSION/UNASSIGNED:The addition of CC stabilization to locking plate fixation in high-risk unstable DCFs results in favorable outcomes and predictable healing rates. LEVEL OF EVIDENCE/UNASSIGNED:IV, case series.
PMCID:13229901
PMID: 42245068
ISSN: 1758-5732
CID: 6044602

Preoperative risk factors associated with patient outcomes following arthroscopic elbow contracture release

Xu, Jacquelyn J; Molokwu, Brian O; Lezak, Bradley A; Shabbir-Hussain, Roban; Sultan, Tanzeel; Myerson, C Lucas; Virk, Mandeep S; Kwon, Young W
BACKGROUND/UNASSIGNED:Elbow contractures can occur due to several causes including age-related degenerative disease, inflammatory conditions, and post-traumatic injury. The resulting pain and reduced range of motion can significantly interfere with activities of daily living and impede patient functionality. One treatment option for elbow contractures is arthroscopic contracture release. The purpose of this study is to evaluate the preoperative risk factors associated with inferior clinical outcomes following arthroscopic elbow contracture release. METHODS/UNASSIGNED:values were adjusted for multiple comparisons using the Bonferroni correction. Postoperative complications, including recurrent contracture, neurological symptoms, and reoperations, were also recorded. RESULTS/UNASSIGNED:= .02) was associated with low postoperative P-UE scores. CONCLUSION/UNASSIGNED:Arthroscopic elbow contracture release can improve function and range of motion; however, outcomes may vary based on preoperative patient characteristics. Female sex may be associated with lower postoperative PROMIS function scores.
PMCID:13100686
PMID: 42027890
ISSN: 2666-6383
CID: 6033142

Comparison of opioid-sparing effect of liposomal vs. nonliposomal bupivacaine for interscalene block in total shoulder arthroplasty: a randomized controlled trial

Virk, Mandeep; Cecora, Andrew; Papalia, Aidan G; Zuckerman, Joseph; Kwon, Young; Hertling, Arthur C
BACKGROUND/UNASSIGNED:Liposomal bupivacaine (LB) was developed to provide longer lasting postoperative analgesia, but its clinical role is still being elucidated. We assessed the opioid-sparing effect of LB in patients undergoing total shoulder arthroplasty (TSA) with an interscalene block (ISB). METHODS/UNASSIGNED:Patients scheduled for TSA were randomized to receive either 20 mL of bupivacaine 5 mg/mL control or 10 ml of bupivacaine 5 mg/mL plus LB 133 mg experimental [EXP] for an ISB. The primary outcome was opioid consumption from 24 to 72 hours. The secondary outcomes were cumulative opioid consumption on postoperative days (PODs) 7, 14, and 30 and pain intensity scores measured by the Patient Reported Outcomes Measurement Information System scale. RESULTS/UNASSIGNED:< .05). CONCLUSION/UNASSIGNED:The addition of LB to plain bupivacaine for an ISB is associated with a statistically significant but not clinically meaningful reduction in opioid consumption over the first 72 hours following TSA. These findings should be considered when making an economical decision to use LB.
PMCID:12145063
PMID: 40486760
ISSN: 2666-6383
CID: 5868942

Projections of utilization of primary and revision shoulder arthroplasty in the United States in the next 40 years

Cecora, Andrew J; Ragland, Dashaun; Vallurupalli, Neel; Ben-Ari, Erel; Xu, Jacquelyn J; Molokwu, Brian O; Kwon, Young W; Zuckerman, Joseph D; Virk, Mandeep S
BACKGROUND/UNASSIGNED:In the past 20 years, the incidence of total shoulder arthroplasty (TSA) has increased greatly, and it is expected to continue growing. Current literature lacks future projections for the utilization of TSA. These projections can help predict demand quantities and anticipate the future burden on the healthcare system. The aim of this study is to determine the predictions of utilization for TSA, primary and revision, through 2060. METHODS/UNASSIGNED:This analysis used the publicly available 2000-2019 data from the Center for Medicare and Medicaid Services Medicare Part-B National Summary. Procedure volumes, including TSA and revision TSA, were determined using Current Procedural Terminology codes and were uplifted to account for the growing number of Medicare eligible patients covered under Medicare Advantage. Log-linear, Poisson, negative binomial regression, and autoregressive integrated moving average models were applied to the procedural volumes to generate projections from 2020-2060. The Poisson model was chosen to display the data based on error analysis and prior literature. RESULTS/UNASSIGNED:The projected annual growth from 2020 to 2060 rates for primary and revision TSA are 11.65% growth (95% confidence interval 11.60%-11.69%) and 13.89% growth (95% confidence interval 13.35%-14.42%), respectively. By 2060, the demand for primary TSA and revision TSA is projected to be 10,029,260 and 1,690,634, respectively. CONCLUSION/UNASSIGNED:The results of this study concluded that both primary and revision TSA procedures are projected to exponentially increase from 2020 to 2060. Additionally, revision procedures are projected to increase at greater rates than their respective primary counterparts.
PMCID:11962609
PMID: 40182257
ISSN: 2666-6383
CID: 5819372

Addition of PROMIS pain instruments to PROMIS upper extremity physical function improves the responsiveness of PROMIS scores compared to legacy scores in patients undergoing total shoulder arthroplasty: a prospective study

Romeo, Paul V; Alben, Matthew G; Papalia, Aidan G; Chowdhury, Tas; Cecora, Andrew J; Ragland, Dashaun; Kwon, Young W; Zuckerman, Joseph D; Virk, Mandeep S
BACKGROUND:Patient-Reported Outcome Measurement Information Systems (PROMIS) is increasingly being utilized across the United States as a patient-reported outcome evaluation tool for a wide variety of musculoskeletal conditions. However, PROMIS Upper Extremity (P-UE) physical function has demonstrated limited responsiveness in the early postoperative period after total shoulder arthroplasty (TSA). The aim of this study is to determine if addition of PROMIS Pain Interference (P-Interference) or Pain Intensity (P-Intensity) scores improve the ability to detect postoperative changes in the 1-year postoperative period following TSA. METHODS:Patients who were indicated for and elected to undergo TSA between 2020 and 2022 were prospectively enrolled. Prospective data were collected for patient surveys (American Shoulder and Elbow Surgeons (ASES), Simple Shoulder Test, P-UE, P-Interference and P-Intensity) at the 2-week, 6-week, 3-month, 6-month, and 12-month timepoints. Instrument responsiveness for each PROM was evaluated using the effect size (ES; Cohen d). Responsiveness was defined by the absolute values of each measurement, previously reported as small (0.2), medium (0.5), or large (0.8). Statistical analysis (2 sample t-tests and Fisher's tests) was performed using R studio version 4.2.3 (Boston, MA, USA). RESULTS:A total of 127 subjects were enrolled in this study. All survey instruments demonstrated large responsiveness (>0.8) at 3, 6, and 12 months. P-Intensity was the only instrument to demonstrate large responsiveness at 2-weeks with its addition to P-UE showing an improved responsiveness at all-time points. Moreover, the addition of P-Intensity had a lower response burden at all-time points when compared to the legacy measures (ASES, Simple Shoulder Test, and Oxford Shoulder Score) at all-time points albeit no difference to ASES (P = .55) at 12-months after surgery. P-Interference and other legacy scores demonstrated large responsiveness starting at 6-weeks postoperatively. CONCLUSION/CONCLUSIONS:The responsiveness of PROMIS UE can be improved by coupling the outcome measure to P-Intensity scores with a significantly lower response burden when compared to the legacy measures evaluated at nearly all time points.
PMID: 39756643
ISSN: 1532-6500
CID: 5804802

Impact of insurance payer type (medicare vs. private) on the patient reported outcomes after shoulder arthroplasty

Romeo, Paul V; Papalia, Aidan G; Cecora, Andrew J; Lezak, Bradley A; Alben, Matthew G; Ragland, Dashaun A; Kwon, Young W; Virk, Mandeep S
BACKGROUND/UNASSIGNED:This study's purpose is to determine if there is a difference in patient-reported outcome measures (PROMs) following shoulder arthroplasty (SA) based upon payer insurance type, with a secondary outcome of determining if any appreciable difference surpasses the minimal clinically important difference (MCID). METHODS/UNASSIGNED:Subjects undergoing anatomic and reverse total shoulder arthroplasty were prospectively enrolled between March 2019 and March 2021. Subjects completed patient reported outcomes measurement information system upper extremity (P-UE), the American Shoulder and Elbow Surgeons score (ASES), and the simple shoulder test (SST) preoperatively and at 2 weeks, 6 weeks, 3 months, 6 months, and 12 months, postoperatively. Descriptive statistics of baseline patient characteristics and preoperative PROMs (ASES, SST, and P-UE) were compared between insurance types. RESULTS/UNASSIGNED: = .4), or SST (0.66). CONCLUSION/UNASSIGNED:Our study demonstrates that, at a tertiary-level academic institution in a metropolitan city, payor type does not have significant impact on achieving MCID or pre-to-postoperative improvements in PROMs after SA.
PMCID:11784262
PMID: 39898232
ISSN: 2666-6383
CID: 5783682

Elbow arthroplasty utilization in 2060: projections of primary and revision elbow arthroplasty in the United States in the next 40 years

Ragland, DaShaun A; Cecora, Andrew J; Vallurupalli, Neel; Ben-Ari, Erel; Kwon, Young W; Zuckerman, Joseph D; Virk, Mandeep S
BACKGROUND:In the past decade, the prevalence of end-stage inflammatory elbow arthritis has declined with consequential changes in indications and utilization of total elbow arthroplasty (TEA). Current literature lacks future projections for the utilization of TEA. The aim of this study is to review the trends in the utilization of TEA in the last 2 decades and determine the projections of utilization for TEA (primary and revision) through 2060. METHODS:This analysis used the publicly available 2000-2019 data from the CMS Medicare Part-B National Summary. Procedure volumes including TEA, and revision TEA, were determined using Current Procedural Terminology codes and were uplifted to account for the growing number of Medicare eligible patients covered under Medicare Advantage. Using these volumes, log-linear, Poisson, negative binomial regression, and autoregressive integrated moving average models were applied to generate projections from 2020 to 2060. The Poisson model was chosen to display the data based on error analysis and prior literature. RESULTS:The projected annual growth rates from 2020 to 2060 for primary and revision TEAs are 1.03% (95% confidence interval: 0.82%-1.25%) and 5.17% (95% confidence interval: 3.02%-6.97%), respectively. By 2060, the demand for primary TEA and revision TEA is projected to be 2084 procedures (95% forecast interval: 1995-2174) and 3161 procedures (95% forecast interval: 3052-3272), respectively. The procedure volume for revision TEA is estimated to outnumber primary TEA by year 2050. CONCLUSION/CONCLUSIONS:The overall procedural volume of primary TEA and revision TEA continues to be low. Although it is estimated that the incidence of primary and revision TEAs will continue to increase in the next 40 years, the utilization trends only show a mild increase, which is 5 times higher for revision TEA than primary TEA.
PMID: 39222741
ISSN: 1532-6500
CID: 5761872

Does the addition of Patient-Reported Outcome Measure Information System (PROMIS) pain instruments improve the sensitivity of PROMIS upper extremity scores after arthroscopic rotator cuff repair?

Alben, Matthew G; Romeo, Paul V; Papalia, Aidan G; Cecora, Andrew J; Kwon, Young W; Rokito, Andrew S; Zuckerman, Joseph D; Virk, Mandeep S
BACKGROUND:Although Patient-Reported Outcomes Measurement Information System (PROMIS) Upper Extremity (P-UE) has been validated in upper extremity orthopedics, its ability to capture a patient's functional recovery after arthroscopic rotator cuff repair (aRCR), as measured by its responsiveness, is minimal in the early postoperative period. The primary purpose of this study is to determine if the addition of PROMIS Pain Intensity (P-Intensity) or Pain Interference (P-Interference) scores to PROMIS UE improves the responsiveness throughout the 1-year postoperative period after aRCR. METHODS:This prospective, longitudinal study included 100 patients who underwent aRCR. Patients completed P-UE, P-Interference, P-Intensity, American Shoulder and Elbow Surgeons, and Western Ontario Rotator Cuff Index scores preoperatively and at 2 weeks, 6 weeks, 3 months, 6 months, and 12 months after surgery. Responsiveness at each time point relative to preoperative baseline and 1-way analysis of variance with post hoc analysis was conducted for each PROM. The responsiveness of the outcome score was determined using the effect size, graded as small (0.2), medium (0.5), or large (0.8). The Pearson correlation coefficient (r) was determined between these instruments at each time point. RESULTS:In isolation, P-UE, P-Interference, and P-Intensity showed a medium-large ability to detect change (positive and negative) throughout the 1-year postoperative period. The addition of PROMIS pain scores to P-UE improved the responsiveness of the instrument (from medium to a large effect size) starting at 3 months and continued throughout the 12-month follow-up period. Although the addition of pain scores increases the response burden for PROMIS, this was still lower than the response burden for the legacy outcome scores (P < .05). CONCLUSION/CONCLUSIONS:The addition of PROMIS pain instruments improves the responsiveness of the P-UE function score in patients undergoing aRCR.
PMID: 39098383
ISSN: 1532-6500
CID: 5730402

Shoulder prosthetic joint infections presenting as atypical sinus tracts - A case series [Case Report]

Contreras, Erik S; Virk, Mandeep S; Kwon, Young W; Zuckerman, Joseph D
PMCID:10920135
PMID: 38464440
ISSN: 2666-6383
CID: 5737632