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High Tibial Osteotomy for Joint Preservation

Lin, Charles C; Alaia, Michael J
High tibial osteotomy shifts the weight-bearing axis of the lower limb away from a diseased medial compartment. It has been associated with high rates of return to work and sport and high midterm to long-term survivorship. However, appropriate patient selection is paramount for achieving optimal outcomes. Factors that can affect outcomes include severity of medial cartilage damage, age, body mass index, and smoking status.
PMID: 40514158
ISSN: 1556-228x
CID: 5869922

Patient-Specific Cutting Guides for Alignment-Correcting Osteotomy About the Knee: A Study of Accuracy, Cost, and Surgical and Fluoroscopic Safety

Savage-Elliott, Ian; Li, Zachary I; Rao, Naina; Triana, Jairo; Garra, Sharif; Chen, Larry; Ranawat, Anil S; Alaia, Michael J; Jazrawi, Laith M
BACKGROUND/UNASSIGNED:The utility and safety of patient-specific cutting guides (PSCGs) in osteotomies about the knee is uncertain. PURPOSE/UNASSIGNED:To compare the cost, accuracy of radiographic correction, and safety of PSCG versus standard cutting guide (SCG) corrective osteotomies about the knee. STUDY DESIGN/UNASSIGNED:Cohort study; Level of evidence, 3. METHODS/UNASSIGNED:Patients undergoing high tibial osteotomy (HTO) or distal femoral osteotomy (DFO) were retrospectively reviewed from 2017 to 2022. Those who underwent 3-dimensional PSCG osteotomy were propensity matched to patients undergoing traditional osteotomies. Procedure time and fluoroscopic details were extracted from operative notes. Hip-knee-ankle (HKA) angle, posterior tibial slope (PTS), and mechanical axis deviation were measured on pre- and postoperative radiographs. Intraclass correlation coefficients were calculated to determine the reliability between the intended and resultant correction of HKA. Time-driven activity-based costing (TDABC) analysis was performed to compare procedure costs. RESULTS/UNASSIGNED:= .01) were lower in the PSCG group. TDABC analysis demonstrated a total cost of $27,026 for PSCG and $27,100 for SCG. The rate of hinge fractures (9.5% vs 33.3%) and return to the operating room (4.8% vs 19.0%) were lower in the PSCG group, although these differences were nonsignificant. CONCLUSION/UNASSIGNED:Both traditionally guided osteotomies and PSCG-guided osteotomies accurately corrected lower extremity malalignment. Utilization of PSCG resulted in similar procedure times and cost, as well as less fluoroscopy and lower tourniquet time, compared with conventional osteotomy. PSCG trended toward a decreased rate of postoperative complications.
PMCID:12280538
PMID: 40697812
ISSN: 2325-9671
CID: 5901532

Donor-recipient sex mismatch does not affect graft survivorship after knee osteochondral allograft transplantation

Lott, Ariana; Triana, Jairo; Sandoval, Carlos G; Sundaram, Vishal; Gonzalez-Lomas, Guillem; Alaia, Michael J; Jazrawi, Laith M; Strauss, Eric J; Campbell, Kirk A
BACKGROUND:This study aims to investigate the effect of donor-recipient sex-mismatch on graft survival, patient-reported outcomes (PROs), and return to sport (RTS) following knee osteochondral allograft (OCA) transplantation. METHODS:Patients who underwent knee OCA transplantation between 2011 and 2022 with minimum 2-year clinical follow-up were divided into two cohorts (same-sex (SS) and different-sex (DS) donor). Cumulative survival was compared via multivariable Cox regression analyses controlling for age, graft size, and body mass index (BMI). A sub-analysis comparing PROs between groups was performed, including the Visual Analog Scale (VAS) for pain and satisfaction, the Knee Injury and Osteoarthritis Outcome Score (KOOS), and RTS rates. RESULTS:285 patients were included (189 SS, 96 DS) with mean follow-up of 4.8 ± 2.0 years. There was a graft failure rate of 6.0% with no significant difference in graft survival rate between DS and SS groups (p = 0.70). Sub-analyses between the four donor-recipient groups (male-male, female-male, male-female, and female-female) and between female and male donor groups demonstrated no significant differences in graft survival. Among patients who failed the procedure, time to failure was significantly shorter for those with sex-mismatched grafts (353 days vs. 864 days, p = 0.002). Sub-analysis of a 71-patient cohort with two-year PROs demonstrated no differences between SS and DS groups with respect to satisfaction, pain, or KOOS scores after controlling for sex (p > 0.05). CONCLUSION/CONCLUSIONS:Patients undergoing knee OCA transplantation demonstrated no observable differences in graft survivorship based on donor-recipient graft sex-matching, suggesting that surgeons can use sex-mismatched grafts and expect limited effect on graft survivorship. LEVEL OF EVIDENCE/METHODS:IV.
PMID: 40505424
ISSN: 1873-5800
CID: 5869542

More negative sagittal tibial tuberosity-trochlear groove distances are correlated with larger patellofemoral chondral lesion size

Bi, Andrew S; Triana, Jairo; Li, Zachary I; Kaplan, Daniel J; Campbell, Kirk A; Alaia, Michael J; Strauss, Eric J; Jazrawi, Laith M; Gonzalez-Lomas, Guillem
PURPOSE/OBJECTIVE:The purpose of this study is to assess the association between sagittal tibial tuberosity-trochlear groove (sTT-TG) distance and patellofemoral chondral lesion size in patients undergoing cartilage restoration procedures. METHODS:A retrospective cohort analysis of patients who underwent an osteochondral allograft transplantation or matrix-induced autologous chondrocyte implantation in the patellofemoral compartment, from 2010 to 2020, were included if they had patellofemoral high-grade lesions, magnetic resonance imaging (MRI) and minimum 2-year follow-up. The preoperative sTT-TG distance was measured independently on axial T2-weighted MRI sequences by two authors, each at least two weeks apart. Intraoperative lesion size was reported according to operative report measurements by the attending surgeon. An interclass correlation coefficient (ICC) was calculated to assess intra- and inter-rater reliability, and categorical data analysis and linear regression models were used to assess the relationship between sTT-TG and lesion size. RESULTS:. Intra- (ICC: 0.99,0.98) and inter-rater reliability (ICC: 0.96) were excellent for both MRI defect size and sTT-TG measurements. The mean sTT-TG was -4.8 ± 4.9 mm and was significantly inversely related to MRI defect size (-0.45, p < 0.01), intraoperative patellar lesion size (-0.32, p = 0.01), total lesion area (-0.22, p = 0.04), but not trochlear lesion size (-0.09, p = 0.56). Multivariable regression demonstrated a more negative sTT-TG remained an independent variable correlated with larger MRI-measured patellofemoral defect sizes and intraoperative patellar lesions. CONCLUSION/CONCLUSIONS:A more negative sTT-TG was an independent variable correlated with larger patellofemoral lesions in patients undergoing patellofemoral cartilage restoration. LEVEL OF EVIDENCE/METHODS:Level III, Diagnostic.
PMID: 39189127
ISSN: 1433-7347
CID: 5729602

Postoperative Pain and Opioid Usage With Combined Adductor Canal and IPACK Block Versus Isolated Adductor Canal Block After Anterior Cruciate Ligament Reconstruction With a Bone-Patellar Tendon-Bone Autograft: A Single-Center Randomized Controlled Trial

Rao, Naina; Triana, Jairo; Avila, Amanda; Campbell, Kirk A; Alaia, Michael J; Jazrawi, Laith M; Furiguele, David; Popovic, Jovan; Strauss, Eric J
BACKGROUND:Efforts to decrease pain, improve early rehabilitation, and reduce opioid consumption have prompted a focus on peripheral nerve blocks for pain management after anterior cruciate ligament reconstruction (ACLR). The commonly used adductor canal block (ACB) might not provide sufficient postoperative pain control because of its lack of coverage of the posterior aspect of the knee. The addition of the IPACK (interspace between the popliteal artery and the capsule of the posterior knee) block, which targets this area, to the standard ACB could potentially provide better pain control after ACLR over the current standard of care. PURPOSE/HYPOTHESIS/OBJECTIVE:The purpose of this study was to compare and analyze postoperative pain, satisfaction, and opioid demand between the standard ACB and a combination of an ACB and IPACK block in patients undergoing ACLR with a bone-patellar tendon-bone (BTB) autograft. It was hypothesized was that the addition of the IPACK block would substantially improve early postoperative pain control and minimize opioid use. STUDY DESIGN/METHODS:Randomized controlled trial; Level of evidence, 2. METHODS:test or nonparametric test for continuous variables and the chi-square test for categorical variables. Opioid usage was reported as morphine milligram equivalents (MME). RESULTS:< .001). CONCLUSION/CONCLUSIONS:The results of this study suggest that the addition of an IPACK block to an ACB leads to reduced opioid consumption, improved pain control, and higher satisfaction with pain control acutely after ACLR with a BTB autograft. REGISTRATION/BACKGROUND:NCT05286307 (ClinicalTrials.gov).
PMID: 40308075
ISSN: 1552-3365
CID: 5833952

No Difference in Clinical Outcomes and Return to Sport & Work with Use of Postoperative Non-Steroidal Anti-Inflammatory Medications Following Primary Arthroscopic Glenoid Labral Repair

Li, Zachary I; Huebschmann, Nathan A; Garra, Sharif; Eskenazi, Jordan; Rettig, Samantha A; Mojica, Edward S; Alaia, Michael J; Strauss, Eric J; Jazrawi, Laith M; Campbell, Kirk A
BACKGROUND:To compare clinical outcomes, return to activities, and rates of revision surgery following arthroscopic glenoid labral repair in patients who were prescribed NSAIDs as part of their postoperative pain management regimen versus those who were not. METHODS:Patients aged 18-55 who underwent primary arthroscopic labral repair at a single academic institution from the years 2016-2020 were retrospectively reviewed. Patients who underwent concomitant rotator cuff repair, remplissage, or did not have minimum 2-year postoperative follow-up were excluded. Patients who were prescribed postoperative NSAIDs were matched 1:1 to those who were not based on age, sex, BMI, and number of suture anchors. Outcomes were assessed using the Visual Analog Scale (VAS) for pain, American Shoulder and Elbow Surgeons Shoulder Score (ASES), Simple Shoulder Test (SST), Single Assessment Numeric Evaluation rating (SANE), and satisfaction. Pre-injury sport and work activity information were recorded. RESULTS:Of 269 eligible patients, 224 patients were included. Patients prescribed NSAIDs postoperatively had similar levels of pain (1.2 vs 1.0, p=0.527) and function (ASES: 90.8 vs 89.9, p=0.824; SST: 91.9 vs 90.6, p=0.646; SANE: 83.8 vs 85.3, p=0.550) compared to those who were not. Rates of revision surgery (2.7% vs 0.9%, p=0.622) and recurrent instability (5.4% vs 8.0%, p=0.594) were similar between NSAID and non-NSAID groups. Rates of return to sport (83.5% vs 77.8%, p=0.318) and return to pre-injury level (59.3% vs 61.6%, p=0.177) were similar between NSAID and non-NSAID groups. Prescription of postoperative NSAIDs was not associated with delayed return to sport (OR:1.47, 95%CI [0.68,3.18], p=0.327) or return to work (OR:0.56, 95%CI [0.14,2.28], p=0.416). CONCLUSIONS:Patients who were prescribed NSAIDs as a part of a postoperative pain management regimen following primary arthroscopic labral repair for glenohumeral instability had similar patient-reported outcomes, revision rates, and rates of return to pre-injury activities compared to those who were not prescribed NSAIDs.
PMID: 40185390
ISSN: 1532-6500
CID: 5819462

Greater Detail Is Needed When Reporting Schenck Knee Dislocation V Injuries in the Orthopaedic Literature: A Systematic Review

Marcel, Aaron J; Levitt, Sarah; Green, Joshua S; Moran, Jay; Jokl, Peter; Schenck, Robert C; Wascher, Daniel C; Alaia, Michael J; Medvecky, Michael J
PURPOSE/UNASSIGNED:To examine how knee dislocations (KDs) with associated periarticular fractures classified using the Schenck KD V subcategory are reported in the literature. METHODS/UNASSIGNED:PubMed, Cumulative Index to Nursing and Allied Health Literature, and Scopus were queried in January 2024. Studies were included if full-text articles in English were available, the Schenck KD classification system was used, and Schenck KD class V was mentioned. The exclusion criteria were as follows: studies in which the Schenck KD classification system was used but only KD classes I to IV were mentioned; systematic reviews, meta-analyses, review articles, commentaries, surgical technique articles, or animal studies; or studies in which pediatric patients were included. Studies were systematically examined for details regarding the descriptions of KD V injuries, including fracture and ligament tear patterns. RESULTS/UNASSIGNED:Seventy-four studies met the inclusion criteria. Of these 74 studies, 45 (60.8%) provided no description of either the ligament tear or fracture patterns that were present in KD V injuries. Fifty-two studies (70.3%) provided no description of the ligament tear patterns and 51 studies (68.9%) provided no description of the fracture patterns associated with KD V injuries. Only 16 of 74 studies (21.6%) included descriptions of ligament tear patterns and fractures present in KD V injuries. CONCLUSIONS/UNASSIGNED:Descriptions of Schenck KD class V are poorly represented in the orthopaedic literature. LEVEL OF EVIDENCE/UNASSIGNED:Level IV, systematic review of Level II to IV studies.
PMCID:12034068
PMID: 40297088
ISSN: 2666-061x
CID: 5833362

"FATAL Graft": A Diagnostic Algorithm for the Workup of Anterior Cruciate Ligament Reconstruction Graft Failure

Bi, Andrew S; Pianka, Mark A; Jazrawi, Laith M; Alaia, Michael J
There are multiple etiologies for revision anterior cruciate ligament reconstruction (ACLR), including but not limited to infection, arthrofibrosis, and graft failure, which should be distinguished before revision ACLR. Graft failure occurs when the reconstructed ligament does not restore knee stability, and it includes both graft rupture and functional failure in the setting of an intact graft. The causes of graft failure following ACLR can be divided into surgeon-controllable factors (ie, tunnel position, graft choice, alignment) and patient-centric factors (ie, patient age, tissue quality from systemic disease or smoking, compliance/traumatic reruptures). The purpose of this review is to propose an organized, easy-to-remember algorithm for the workup of surgeon-controlled ACLR graft failure etiologies, represented by the acronym "FATAL Graft."
PMID: 40138439
ISSN: 1940-5480
CID: 5815912

Surgeon experience in multi-ligament knee injury reconstruction is associated with decreased complications and surgical time

Berzolla, Emily; Lezak, Bradley A; Magister, Steven; Moore, Michael; Strauss, Eric J; Jazrawi, Laith M; Alaia, Michael J
INTRODUCTION/BACKGROUND:Operative management of multi-ligament knee injuries (MLKI) is technically challenging, with high complication rates. However, the impact of surgeon experience on surgical outcomes remains underreported. This purpose of this study was to examine how surgeon experience impacts operative time and complication rates. It was hypothesized that increased surgeon experience in MLKI correlates with reduced surgical duration and postoperative complications. METHODS:A retrospective review of MLKI patients who underwent reconstruction from 2011 to 2024 by fellowship-trained sports medicine surgeons at two high-volume level 1 trauma centers was conducted. Patient demographics, surgical procedure characteristics, complications, and surgeon experience (defined by years in practice postfellowship) were analyzed. Correlations were examined using linear regression for continuous variables and binary logistic regression for binary variables. RESULTS:There were 191 MLKI patients meeting inclusion criteria, with a 25.7% overall complication rate. Arthrofibrosis (16.2%) was most common, followed by recurrent instability (3.7%), infection (3.7%), revision surgery (2.7%), and hardware removal (1.0%). Controlling for age, sex, BMI, and number of ligaments reconstructed, we found a significant negative correlation between surgeon experience and both surgical duration (ß =  - 0.28, p < .001) and complication risk (OR 0.92, p = 0.024). CONCLUSION/CONCLUSIONS:This study demonstrates that increased surgeon experience in operative management of MLKI is associated with decreased complication rates and shorter procedure duration. Additional risk factors for complications included the number of ligaments injured and concomitant knee dislocation.
PMID: 40050527
ISSN: 1432-1068
CID: 5809842

Feasibility of a UTE Stack-of-Spirals Sequence for Biexponential T Mapping of Whole Knee Joint

de Moura, Hector L; Keerthivasan, Mahesh B; Zibetti, Marcelo V W; Su, Pan; Alaia, Michael J; Regatte, Ravinder
This study aimed to develop and evaluate a novel magnetization-prepared, ultra-short echo time (UTE)-capable, stack-of-spirals sequence (STFL) to quantify monoexponential and biexponential T maps of the whole knee joint, addressing limitations of existing MRI techniques in assessing bone-patellar tendon-bone (BPTB) donor site healing and graft remodeling after anterior cruciate ligament (ACL) reconstruction (ACLR). Experiments were performed with agar-gel model phantoms, seven healthy volunteers (four males, average age 31.4 years old), and five ACLR patients (three males, average age 28.2 years old). Compared with a conventional Cartesian turbo fast low angle shot (CTFL) sequence, the STFL sequence demonstrated an improved signal-to-noise ratio (SNR), increasing from 16.5 for CTFL to 21.7 for STFL. In ACLR patients, the STFL sequence accurately detected increased fractions of short T components within the ACL graft, rising from 0.15 to 0.38, compared with 0.11 to 0.18 with CTFL. Furthermore, the STFL sequence revealed significant decreases in the fraction of short T components in the patellar tendon of ACLR patients (from 0.6 to 0.47) compared with healthy controls, whereas no significant changes were observed with the CTFL sequence. These findings suggest that the STFL sequence holds promise for noninvasive assessment of BPTB donor site healing and graft maturation following ACLR.
PMID: 39929189
ISSN: 1099-1492
CID: 5793212