Faculty Bibliography

OBJECTIVES/OBJECTIVE:Early screening is necessary to prevent increasing osteoporosis and fragility fractures. Though Dual-energy X-ray absorptiometry (DEXA) defines osteoporosis, it does not predict fragility-fractures well. Trabecular structure as seen on MRI may be more sensitive and specific for osteoporosis and distal radius trabecular structure may identify changes earlier. We aimed to compare distal-radius trabecular structure as seen on MRI in patients with normal risk for fragility-fracture to those with increased risk of fragility-fracture. METHODS:Ten low-risk and 9 high-risk subjects underwent ultra- short-echo-time (UTE) MRI sequence scanning of an uninjured distal radius. Structural components included: trabecular plate-width, plate-rod ratio, plate volume fraction, rod volume fraction, trabecular thickness, pore size, pore size variation and trabecular density. A T-test or Mann-Whitney U test was conducted to determine differences in trabecular structure between low- and high-risk groups. Specificity and sensitivity were calculated to assess wrist MRI as a screening tool. RESULTS:There were statistically significant differences between low- and risk-risk groups for all parameters except trabecular thickness (p < 0.05). CONCLUSION/CONCLUSIONS:This study supports the feasibility of wrist MRI as a screening tool for early osteoporosis. This could potentially enable early prevention. Further study including longitudinal follow-up to determine the ability of this tool to predict fragility fractures is needed. ADVANCES IN KNOWLEDGE/CONCLUSIONS:We compared trabecular structure in wrist-MRI of high-risk and low-risk for fragility fracture, finding significant differences with optimal sensitivity/specificity to predict osteoporosis. Wrist MRI may offer early and effective screening for osteoporosis.

We report on cases of isolated fourth extensor compartment tenosynovitis without evidence of systemic inflammation that occurred in the context of alteration in the work environment due to the COVID-19 epidemic. Early identification of the deleterious effects of virtual/technologically-dependent work from home can aid in treatment and prevention of these conditions. We describe the phenomenon and suggest a treatment approach.

PURPOSE/OBJECTIVE:Early diagnosis and treatment of scaphoid fractures is critical to achieve union and prevent wrist degenerative arthritis. Plain radiographic measurements can guide the early approach to suspected fractures. Specifically, the ability to predict fracture or fracture stability from plain radiographs may allow the traumatologist to expand initial referral to three-dimensional imaging. We evaluated the ability of four measured angles to predict presence of a scaphoid fracture and stability. METHODS:Fifty patients with a scaphoid fracture and 50 patients without fracture were evaluated for the cortical ring sign, scapho-lunate gapping, lateral scapholunate (SL), radio-scaphoid (RS), radio-lunate (RL), and radio-capitate (RC) angles by two-blinded observers. RESULTS:Measurement of an increased SL interval was associated with the presence of a scaphoid fracture as diagnosed on three-dimensional imaging [odds ratio (OR) 3.0, confidence interval (CI) 1.53-5.87, p =  < 0.01]. The measured RL angle was associated with fracture displacement (OR 1.13, 95% CI 1.02-1.25, p = 0.02). CONCLUSIONS:Scapholunate gapping on plain radiographs in the context of a clinically suspected scaphoid fracture should increase suspicion for a fracture and may prompt earlier 3-dimensional imaging, while the presence of an abnormal radiolunate angle should increase wariness for instability and can be used in preoperative planning.

Cryptococcal infection is well-documented in immunocompromised individuals. Cutaneous manifestations are not as common and are often difficult to diagnose due to variable presentations. Furthermore, there have been reports of coexisting cutaneous Cryptococcus and malignancy. We describe a patient that presented with a fast-growing mass (suspected sarcoma) in the hand that was ultimately treated for a Cryptococcus skin infection. We believe familiarity with the possibility of coexistence of these two conditions in an immunocompromised host could have brought about earlier diagnosis and possibly more effective treatment. Level of Evidence: Level V (Therapeutic).

BACKGROUND:Cubital tunnel syndrome and the resulting loss of hand dexterity and strength may necessitate surgical management. Studies have demonstrated no difference in outcome between surgical techniques. In an attempt to leave more ulnar nerves in situ while providing for stability within the cubital tunnel, we suggest a surgical treatment approach. METHODS:The approach addresses individual anatomy methodically, eliminating muscular obstruction first and providing further decompression and stability as required. A retrospective review of 27 adult patients with ulnar neu- ropathy treated according to this method was performed. RESULTS:The mean duration of symptoms prior to surgery was 2.75 years (SD = 2.4). The mean follow-up was 17.1 months (SD = 16.9). All patients improved following surgery. Two revision surgeries were performed 4 years following the original surgery. CONCLUSIONS:We believe the nerve recovers best when left in situ, provided it is stable and not compressed within the cubital tunnel. A further comparison study is necessary to substantiate the advantage of this "personalized" approach over other surgical techniques for cubital tunnel release.