Try a new search

Format these results:

Searched for:

in-biosketch:true

person:ceradd01

Total Results:

131


Experience with injectables performed at a resident department Aesthetic Surgery Clinic

Boyd, Carter J; Nasr, Hani Y; Cassidy, Michael F; Borab, Zachary M; Vranis, Neil M; Gursky, Alexis K; Gober, Rebecca; Zide, Barry M; Ceradini, Daniel J
BACKGROUND/UNASSIGNED:The popularity and rapid growth of aesthetic injectables, in conjunction with the influx of competing specialties performing these procedures, underscores the importance of competence of plastic surgery residents and rigorous modalities of plastic surgery training. OBJECTIVES/UNASSIGNED:Our objective was to review injectables and outcomes from our plastic surgery resident aesthetic clinic. Outcomes and costs were compared to national averages and reports from the literature. METHODS/UNASSIGNED:A retrospective chart review identified all adult injectable patients at the Resident Aesthetic Surgery Clinic at NYU Langone Health in 2021. Patient demographics, procedural data, complications, touch-ups, and surgeon fees were compiled. Factors predictive of return patronage were investigated as well. Data were analyzed and visualized in R. RESULTS/UNASSIGNED:In 2021, 223/233 consultations led to an injection (95.7% conversion rate) for 148 patients. Neurotoxin was most commonly injected into the upper face, while fillers were most commonly injected into the midface. Two complications from fillers (0.9% complication rate) and one touch-up (0.4% touch-up rate) were recorded. Surgeon fees were substantially less than national averages and comparable to other academic settings. Patients who received filler only at their first visit were significantly less likely to be return patrons in the same year. CONCLUSIONS/UNASSIGNED:These data represent the largest and most detailed annual report of injectables from a plastic surgery resident aesthetic clinic, demonstrating high volume, low complication and revision rates, and reasonable costs to patients. Altogether, our study supports resident aesthetic clinics as a robust training modality.
PMCID:12891776
PMID: 41684546
ISSN: 2352-5878
CID: 6002552

Logistical, Ethical, and Technical Considerations in the World's First Face and Whole Eye Transplantation

Chinta, Sachin R; Tran, David L; Shah, Alay R; Ceradini, Daniel J; Dedania, Vaidehi S; Gelb, Bruce E; Cohen, Oriana D; Flores, Roberto L; Levine, Jamie P; Saadeh, Pierre B; Staffenberg, David A; Rojas, Allison C; Rodriguez, Eduardo D
BACKGROUND:Whole eye transplantation (WET) has long been looked to as a potential solution for the aesthetic and functional deficits caused by severe ocular pathology and trauma. Here, we describe the first successful combined face and whole eye transplantation (FT/WET), highlighting the logistical, ethical, and technical considerations that enabled this milestone. METHODS:A 46-year-old male with severe facial and ocular deficits underwent multidisciplinary evaluation and was deemed a candidate for FT/WET. Subsequently, a surgical algorithm was developed through rigorous preoperative planning and team based surgical simulations. This process focused on techniques that would allow for efficient graft procurement and inset, while simultaneously limiting trauma to the globe and its adnexa. RESULTS:Longitudinal monitoring demonstrated maintained graft viability throughout the postoperative period. Fluorescein angiography and ICG angiography confirmed robust retinal and choroidal perfusion. Diffusion-weighted MRI revealed structural preservation of the optic tracts, despite inner retinal atrophy. The patient has also experienced significant improvement in facial aesthetics and functionality with no episodes of graft rejection to date. CONCLUSIONS:This case demonstrates the feasibility of addressing deficits once deemed irreparable through advanced surgical techniques, preoperative planning, and multidisciplinary collaboration. Although functional vision recovery has not been observed, this innovation expands the reconstructive options available for patients with severe facial and ocular deficits, paving the way for future advancements in vascularized composite allotransplantation.
PMID: 41467696
ISSN: 1529-4242
CID: 5985642

Current Trends in Facelift and Necklift Procedures

Boyd, Carter J; Ceradini, Daniel J
Many surgical and nonsurgical options are available to patients seeking facial rejuvenation. In this review, we aim to provide an overview of the current trends in facelift and necklift procedures while simultaneously highlighting the utility of nonsurgical treatments. A comprehensive literature review was performed using the PubMed, Google Scholar, and Cochrane Library databases, with the objective of including recent literature published on facelift and necklift procedures from 2015 to 2025. Articles were selected based on relevance, with a specific focus on including a wide breadth of techniques. A considerable body of literature has been published to further classify the soft-tissue anatomy of the face and neck. In particular, these studies focus on the characterization of the three-dimensional anatomy of the facial nerve with emphasis on safe planes of dissection to avoid inadvertent facial nerve injury. The current literature continues to debate both the theoretical and practical advantages and disadvantages of various facelift techniques. Broadly speaking, facelift techniques can be divided into those that manipulate the superficial musculoaponeurotic system (SMAS) layer on its superficial surface and those that undermine the SMAS to varying extents. Numerous approaches are available to improve the contour of the neck and jawline, including manipulation of the platysma muscle and subplatysmal volume reduction. Other surgical procedures and nonsurgical treatments should be considered to optimize and enhance facelift and necklift results. Advancements in patient safety include a focus on minimizing complications while reducing the length of recovery. Facelift and necklift procedures remain the foundational pillars for facial rejuvenation. With attention to patient-specific anatomy, surgeons can work collaboratively with patients to provide global facial optimization by choosing appropriate facelift and necklift techniques in combination with other ancillary procedures. Doing so will deliver enduring, elegant results.
PMCID:12193931
PMID: 40566019
ISSN: 2077-0383
CID: 6070758

Quality of life and body contouring surgery in adolescents after bariatric surgery: A scoping review

Perez-Otero, Sofia; Aponte Rivera, Hermes A; Alfonso, Allyson R; Tashiro, Jun; Ceradini, Daniel J
BACKGROUND:Body contouring surgery (BCS) is a common postoperative trajectory for adults following bariatric surgery, yet research on its application to adolescents is lacking. This scoping review aimed to map the available literature on quality of life (QoL) and potential for BCS in adolescents after bariatric surgery. METHODS:This review followed the Joanna Briggs Institute (JBI) guidance for scoping reviews and is reported in accordance with the PRISMA extension for Scoping Reviews (PRISMA-ScR). Three electronic databases were queried for studies regarding QoL and BCS in adolescents following bariatric surgery within the last 20 years. A descriptive and thematic analysis was conducted. RESULTS:Twenty-three studies met inclusion criteria. A total of 19 (82.6%) evaluated QoL and 4 (17.4%) explored the role of BCS in adolescents following bariatric surgery. The most common method of data collection was prospective study (65.2%). Two themes were described: QoL after bariatric surgery, which expressed improvement in several domains within 6 months, and role for BCS, which showed high interest in addressing residual excess skin and appearance. Gaps in the literature were identified, including a need for studies exploring mediators of QoL, predictors of compliance, and outcomes of BCS. CONCLUSIONS:Studies describing residual symptoms and BCS in adolescents following bariatric surgery are lacking. BCS may complement bariatric surgery, but further research must be conducted to assess its safety in adolescents. By addressing the research gaps described in this review, physicians may have a better understanding of the needs of this population and how to counsel them. LEVEL OF EVIDENCE AND TYPE OF STUDY/UNASSIGNED:Level IV; Systematic Scoping Review.
PMID: 41353018
ISSN: 1538-3199
CID: 5975462

Swallowing Function After Pioneering Partial Face and Whole Eye Transplant: Clinical Insights

Lico, Margaret; Hanley, Kaitlin; Shah, Alay; Chinta, Sachin; Ceradini, Daniel J; Rodriguez, Eduardo D
PURPOSE/UNASSIGNED:There is limited literature reporting swallowing outcomes in the pre- and postoperative period for patients undergoing facial transplantation. This case report aims to utilize a combination of objective and patient-reported outcome measures to highlight swallowing improvements following the world's first face with whole-eye transplantation. METHOD/UNASSIGNED:Outcome measures in jaw range of motion, anterior containment, texture progression, airway protection, and pharyngeal swallow function were collected pretransplantation by two speech-language pathologists (SLPs) and at multiple postoperative visits after the procedure was completed. Specific outcome measures included the Gothenburg Trismus Questionnaire, Maximal Incisor Opening, Modified Teachers Drooling Scale, Functional Oral Intake Scale, Eating Assessment Tool-10, The Penetration-Aspiration Scale, and the Modified Barium Swallow Study Impairment Profile. Measures were then compared over a 1-year time period to assess changes in swallow function. RESULTS/UNASSIGNED:Improvements in jaw range of motion, anterior containment, and airway protection were observed. The patient's stated goal of returning to full PO diet following face transplant was achieved within 1 year. CONCLUSIONS/UNASSIGNED:Swallowing and trismus outcome measures are an important tool for monitoring progress along a patient's recovery journey, especially following unique procedures such as face transplantation. Based on this single patient case study, facial transplantation can lead to improvements in both objective and patient-reported outcomes. Future goals for research should continue to explore this unique population due to the limited literature available for SLPs, as well as include development of valid and reliable assessment tools specific to the face transplantation population.
PMID: 40403408
ISSN: 1558-9110
CID: 5853442

New Paradigms in Rejection Monitoring: Lymphocyte Subsets as Noninvasive Graft Markers in Vascularized Composite Allotransplantation

Chinta, Sachin R; Shah, Alay R; Tran, David L; Lee, Wen-Yu; Mangiola, Massimo; Gelb, Bruce E; Ceradini, Daniel J; Rodriguez, Eduardo D
BACKGROUND/UNASSIGNED:In vascularized composite allotransplantation, face transplantation stands as a transformative intervention for patients with severe facial disfigurement. Monitoring of graft rejection, however, remains a critical challenge. This study aimed to investigate the role of lymphocyte subsets in the early detection and monitoring of graft rejection in face transplantation. METHODS/UNASSIGNED:We conducted a retrospective chart review of 3 face transplant recipients who underwent face transplantation at our institution. Peripheral blood samples were analyzed for lymphocyte subsets at multiple time points posttransplantation. A linear mixed-effects model was used, aiming to identify any upregulation associated with episodes of graft rejection. RESULTS/UNASSIGNED:= 0.0015, respectively). CONCLUSIONS/UNASSIGNED:Our study demonstrates that monitoring specific lymphocyte subsets offers a promising adjunct for graft surveillance that is less invasive when compared with traditionally used punch biopsies. This approach not only enhances the precision of rejection monitoring but also improves patient comfort and compliance, thereby contributing to better long-term graft outcomes.
PMCID:11884835
PMID: 40051973
ISSN: 2169-7574
CID: 5842872

Current Trends in Deep Plane Neck Lifting: A Systematic Review

Chinta, Sachin R; Brydges, Hilliard T; Laspro, Matteo; Shah, Alay R; Cohen, Joshua; Ceradini, Daniel J
INTRODUCTION/BACKGROUND:The aging neck is a prevalent aesthetic concern, with over 160,000 neck procedures performed in 2020. It is characterized by increased soft tissue laxity and displacement of cervical structures. While nonsurgical interventions like cryoablation and laser resurfacing show promise, their variable responses highlight the necessity for surgical solutions. Traditional neck lifts address superficial structures but often neglect the subplatysmal plane. Recently, deep plane neck lifts have gained attention for addressing deeper anatomical structures. This paper systematically reviews the literature on subplatysmal modifications in cervicoplasty, aiming to clarify the risks and benefits of these evolving surgical techniques. METHODS:On February 20, 2024, a systematic review adhering to Preferred Reporting Items for Systematic Review and Meta-Analyses 2020 guidelines was performed. MEDLINE, PubMed, Cochrane, and Scopus databases were searched for terms related to neck rejuvenation. Independent reviewers screened titles, abstracts, and full texts, including all relevant studies. Data extracted included patient numbers, procedures, outcomes, and complications. RESULTS:From an initial 771 articles, 57 studies encompassing 8648 patients met inclusion criteria. The most commonly altered anatomical structures during "deep plane" neck lift (DPNL) were the submandibular gland (69.9%), digastric muscles (58.6%), and subplatysmal fat (48.6%). Postoperative complications were reported in 59.6% of studies, with nerve palsy (0.2%-12%) and hematoma (0.2%-4%) being most common. Aesthetic outcomes were less frequently reported (56% of studies); patient satisfaction ranged from 81.6% to 98.6%, while objective measures were reported in only 12% of studies. CONCLUSIONS:Recent surveys indicate a growing concern over excess laxity under the chin, with patients increasingly seeking neck rejuvenation. Our review found that DPNL techniques vary widely, with the submandibular gland and digastric muscles being the most frequently altered structures. Despite a general lack of standardized outcome measures, patient satisfaction was high. However, DPNL showed a higher rate of postoperative nerve palsy compared to traditional neck lift. Overall, while DPNL demonstrates potential aesthetic benefits, the increased risk necessitates thorough patient counseling and further studies for standardization and comparison.
PMID: 39652837
ISSN: 1536-3708
CID: 5762382

Molecular Signature Associated With Acute Rejection in Vascularized Composite Allotransplantation

Cassidy, Michael F; Doudican, Nicole A; Frazzette, Nicholas; Rabbani, Piul S; Carucci, John A; Gelb, Bruce E; Rodriguez, Eduardo D; Lu, Catherine P; Ceradini, Daniel J
BACKGROUND/UNASSIGNED:A deeper understanding of acute rejection in vascularized composite allotransplantation is paramount for expanding its utility and longevity. There remains a need to develop more precise and accurate tools for diagnosis and prognosis of these allografts, as well as alternatives to traditional immunosuppressive regimens. METHODS/UNASSIGNED:Twenty-seven skin biopsies collected from 3 vascularized composite allotransplantation recipients, consisting of face and hand transplants, were evaluated by histology, immunohistochemistry staining, and gene expression profiling. RESULTS/UNASSIGNED:significantly predicted inflammation specific to vascularized composite allografts that required therapeutic intervention. CONCLUSIONS/UNASSIGNED:The mechanism of vascularized composite allograft-specific inflammation and rejection appears to be conserved across different patients and skin on different anatomical sites. A concise gene signature can be utilized to ascertain graft status along with a continuous scale, providing valuable diagnostic and prognostic information to supplement current gold standards of graft evaluation.
PMCID:11415116
PMID: 39310283
ISSN: 2373-8731
CID: 5802822

Analyzing Epidemiology and Hospital Course Outcomes of LeFort Fractures in the Largest National Pediatric Trauma Database

Perez Otero, Sofia; Cassidy, Michael F; Morrison, Kerry A; Brydges, Hilliard T; Muller, John; Flores, Roberto L; Ceradini, Daniel J
STUDY DESIGN/UNASSIGNED:Retrospective observational study. OBJECTIVE/UNASSIGNED:This study analyzes the epidemiology of pediatric Le Fort fractures and assesses the incidence of concomitant injuries and acute-level hospital course using the largest, national pediatric trauma database to date. METHODS/UNASSIGNED:Pediatric midface and Le Fort fractures from 2016-2019 were identified in the National Trauma Data Bank. Descriptive analyses of Le Fort compared to non-Le Fort midface fractures were performed. Multivariable regression assessed whether Le Fort fractures were risk factors for ICU admission, intracranial injury, cervical spine (C-spine) fracture, tracheostomy, and mortality. RESULTS/UNASSIGNED:< 0.001). Incidence of all the above increased with higher-grade Le Fort fractures. Le Fort III fractures had higher rates of mortality than non-Le Fort midface fractures (7.6% vs 3.2%). Multivariable regression showed that all Le Fort patterns were independent risk factors for tracheostomy and ICU admission, but only Le Fort I for C-spine fractures. CONCLUSIONS/UNASSIGNED:The incidence of Le Fort fractures appears to increase with age. Higher category Le Fort fractures are associated with greater morbidity.
PMCID:11562997
PMID: 39553809
ISSN: 1943-3875
CID: 5758012

The Evolving Plastic Surgery Applicant: How Far Have We Come in 30 Years?

Hemal, Kshipra; Perez-Otero, Sofia; Boyd, Carter J; Weichman, Katie E; Cohen, Oriana D; Thanik, Vishal D; Ceradini, Daniel J
BACKGROUND:Plastic surgery training has undergone tremendous change and transitioned through many models over the years, including independent, combined, and integrated. This study evaluates how these changes and others have affected plastic surgery applicants' demographics and academic qualifications over the last 30 years. METHODS:Data on applicant demographics and academic qualifications were extracted from multiple sources including the National Resident Matching Program, the American Association of Medical Colleges, and cross-sectional surveys of plastic surgery applicants for the years 1992, 2005, 2011, and 2022. Data were compared using pairwise χ2 goodness of fit tests. RESULTS:The sex distribution of plastic surgery applicants changed significantly over the last 30 years: whereas men predominated in 1992 (86% male vs 14% female), by 2011, the distribution was nearly equal (54% male vs 46% female in both 2011 and 2022, P < 0.001).The racial makeup of applicants also changed over time (P < 0.05). White applicants decreased from 73% in 1992 to 55% in 2011, and 53% in 2022. While there was an increase in Asian (7% to > 17% to > 20%) and other (13% to > 14% to > 21%) applicants over time, whereas the proportion of Black applicants remained stagnant (5% to > 6% to > 8%).Applicants with prior general surgery experience declined precipitously over the years: 96% in 1992, 64% in 2005, 37% in 2011, and 26% in 2022 (P < 0.001). When compared with 1992, Alpha Omega Alpha status increased significantly in 2011 (36% vs 12%, P < 0.05) but did not change considerably in 2005 (22%) and 2022 (23%). Research experience increased dramatically over the years, with the proportion of applicants with at least one publication going from 43% in 1992, to 75% in 2005, to 89% in 2011, and to 99% in 2022 (P < 0.001). Applicant interest in academic plastic surgery did not change considerably over the years at roughly ranging from 30% to 50% of applicants (P = ns). CONCLUSIONS:There has been a shift in the demographics and academic qualifications of plastic surgery applicants over the last 3 decades. Understanding this evolution is critical for reviewing and evaluating the makeup of our specialty, and enacting changes to increase representation where necessary.
PMID: 38556682
ISSN: 1536-3708
CID: 5728942