Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection: an international cohort study
Aaraj, Mahmoud A; Abate, Emmanuele; Abbott, Sarah J; Abbott, Tom Ef; Abdalaziz, Hossam; Abdalla, Mutwakil Om; Abdelaal, Ahmed S; Abdelkarim, Mostafa; Abdou, Hossam; Aboelkassem-Ibrahim, Ahmad; Abou Chaar, Mohamad K; Abuown, Ala; Acebes-Garcia, Fernando; Acharya, Metesh; Adamina, Michel; Addae-Boateng, Emmanuel; Ademuyiwa, Adesoji O; Aftab, Raiyyan; Agarwal, Arnav; Aguilar, José; Aherne, Thomas M; Ahmed, Yousra; Aitken, Emma; Al Maadany, Faraj S; Al-Azzawi, Marwa; Al-Embideen, Somya; Al-Masri, Mahmoud; Al-Najjar, Hani; Al-Sukaini, Ahmad; Alakaloko, Felix; Alam, Ruhina; Alameer, Ehab; Alanbuki, Ammar; Alderson, Derek; Ali Karar, Ali A; Ali, Inthekab Ali Mohamed; Ali, Osman M; Aliyeva, Zumrud; Aljanadi, Firas; Alkadeeki, Ghadah Z; Almasri, Murad; Almeida, Ana C; Alonso-Ortuño, Paula; Alrahawy, Mahmoud M; Alser, Osaid; Altintoprak, Fatih; Alvarez, Maria R; Ambler, Graeme K; Amira, Gamal; Amjad, Rabbia; Anania, Gabriele; Andabaka, Tatjana; Andreani, Stefano M; Angelou, Dimitrios; Annamalai, Seethalakshmi; Annessi, Valerio; Anthoney, James; Antonanzas, Leyre Lopez; Anwar, Sibtain; Anwer, Mariyah; Aoun, Salah G; Aragon-Chamizo, Juan; Archer, James E; Ardito, Antonella; Arigoni, Michele; Armao, Teodora; Arminio, Armando; Armstrong, Lara; Arnaud, Alexis; Arnaud, Alexis P; Asaad, Peter; Ashcroft, James; Ashmore, Christopher; Ashoush, Fouad M; Asqalan, Ahmad; Asti, Emanuele; AtaÃde Gomes, Gustavo Mendonça; Aubry, Emmanuelle; Augestad, Knut Magne; Avellana, Rocio B; Ayeni, Funbi A; Ayorinde, John Oo; Aytac, Erman; Ayuso-Herrera, Esther; Babu, Bheemanakone H; Baeza, Melody; Baig, Mirza Mas; Bailon-Cuadrado, Martin; Bajomo, Oreoluwa M; Baker, Markus P; Baker, Olivia J; Bakmaz, Bernarda; Bakri, Nur Amalina Che; Baldi, Caterina; Baldini, Edoardo; Baldo, Stefano; Baldwin, Alexander J; Ballabio, Michele; Baloyiannis, Ioannis; Baltazar, Gerard; Ban, Vin Shen; Bandiera, Alessandro; Bankhead-Kendall, Brittany K; Barlow, Emma; Barmasse, Roberto; Barmpagianni, Christina; Baron, Ryan D; Baronio, Gianluca; Barra, Fabio; Barranquero, Alberto G; Barry, Conor P; Bartsch, Anne-Marie; Basgaran, Amedra; Basha, Amr; Bashkirova, Varvara; Bass, Gary A; Bastazza, Marco; Bath, Michael F; Batjer, H Hunt; Baumber, Rachel; Bauset, Juan Carlos Catalá; Beamish, Andrew J; Belcher, Elizabeth; Belgaumkar, Ajay P; Beltrán de Heredia, Juan; Belvedere, Angela; Bence, Matthew N; Benson, Ruth A; BenÃtez-Linero, Inmaculada; Bergeat, Damien; Bernal-Sprekelsen, Juan Carlos; Bernasconi, Matteo; Bhalla, Ashish; Bhama, Anuradha R; Bhangu, Aneel; Bhavaraju, Avi V; Bhutiani, Neal; Bianco, Federica; Biffl, Walter L; Bisagni, Pietro; Blake, Iain; Blanco-Colino, Ruth; Blas Laina, Juan Luis; Blazer Iii, Dan G; Blazquez-Martin, Alma; Blundell, Chris M; Boal, Matthew; Boddy, Alexander P; Bonavina, Giulia; Bonavina, Luigi; Bond-Smith, Giles; Booth, Karen; Borges, Filipe; Borghi, Felice; Borgstein, Alexander Bj; Borja De Lacy, F; Bosanquet, David C; Bosch, Karen D; Bouchagier, Konstantinos; Bouhuwaish, Ahmad Em; Bourke, Grainne; Boyle, Emily; Bozkurt, Mehmet A; Brachini, Gioia; Brain, Jessie; Brar, Amanpreet; Brathwaite, Collin Em; Breckles, Lisa; Breen, Kerry A; Bretagnol, Frédéric; Brixton, Genevieve; Brown, Allison K; Brown, Benjamin C; Brown, Oliver D; Bruzzaniti, Placido; Buarque, Igor Lima; Bueno-Cañones, Alejandro D; Bueser, Teofila; Bulugma, Mustafa R; Burke, Joshua R; Burnside, Nathan; Byrne, Matthew Hv; Bà mbina, Fabrizio; Caballero, Albert; Cagigal-Ortega, Elima P; Calcerrada-Alises, Enrique; Callahan, Miriam; Callcut, Rachael A; Camarero, Enrique; Campagnaro, Tommaso; Campanelli, Michela; Candiani, Massimo; Cannoletta, Maria; Canova, Michaela E; Cantalejo-Diaz, Miguel; Cao, Han; Capelli, Patrizio; Capitan-Morales, Luis-Cristobal; Capizzi, Vita; Carcano, Giulio; Carissimi, Francesca; Carlini, Massimo; Carlos, William J; Carlucci, Michele; Carmichael, Heather; Carrasco, Milagros; Carrillo, Mariana; Caruana, Edward J; Carvello, Michele; Casati, Massimiliano; Castoro, Carlo; Catalan, Vanesa; Cato, Liam D; Catton, Andrew B; Cavaleiro, Salomé; Cellerino, Paola; Centinaio, Giovanna; Ceretti, Andrea Pisani; Cernei, Cristina; Cerro, Cristina; Cervellera, Maurizio; Chakrabortee, Sohini; Chamberlain, Stephanie; Chan, Jeffrey; Chang, Grace; Chase, Thomas Jg; Chaudhry, Dauod; Chebaro, Alexandre; Chen, David; Chetty, Govind; Chia, Zoe; Chiappini, Ambra; Chiara, Francesco Di; Chiarugi, Massimo; Chidambaram, Swathikan; Chiozza, Matteo; Cholewa, Hanna; Chong, Clara; Choolani-Bhojwani, Ekta; Chowdhury, Abeed H; Chrastek, David; Christoforidis, Dimitri; Chui, Karen; Chung, Choyin; Chung, Eric A; Cicerchia, Pierfranco M; Cirillo, Bruno; Citterio, Davide; Clermidi, Pauline; Clough, Ethan Cs; Coccolini, Federico; Coleman, Natasha L; Colletti, Gaia; Collins, Chris G; Collins, Michelle L; Colonna, Emily T; Comini, Lara V; Compagnoni, Bruno; Concepción-MartÃn, Vanesa; Confalonieri, Marco; Connelly, Tara M; Connolly, Hannah; Conso, Christel; Conti, Luigi; Cooper, Zara; Corbellini, Carlo; Cordera, Fernando; Corral, Javier; Costa, Marta; Costa, Paulo Matos; Costanzi, Andrea; Cotsoglou, Christian; Coughlin, Patrick A; Cox, Daniel; Cozza, Valerio; Cruzado, Laura Fernández-Gomez; Cuming, Tamzin; Cunha, Miguel F; Curtis, Miles; Cuschieri, Joseph; D'Agruma, Michele; D'Andrea, Giancarlo; Da Roit, Anna; Daliya, Prita; Dare, Oliver; Darko, Ebenezer; Dass, Debashis; Davidson, Brian R; Davidson, Giana H; Davies, Emma J; Davies, Richard J; Davis, Niall F; Dawson, Brett E; Day, Andrew; De Andrés-Asenjo, Beatriz; de Gheldere, Charles A; De Marchi, Joshua A; De Miguel-Ardevines, Maria-Carmen; De Nardi, Paola; De Salas, Maria Marqueta; De Simone, Veronica; De Souza, Anthony C; De Toma, Giorgio; De Virgilio, Armando; de Vries, Jean-Paul Pm; Dean, Benjamin Jf; Dean, Harry; Dehal, Ahmed; Dehart, Dustin; Del Giudice, Roberto; Delgado, Maria Garcia-Conde; Delgado-Oliver, Eduardo; Denning, Max; Desai, Anant; Desender, Liesbeth; Dester, Sara; DI Bartolomeo, Alessandro; DI Candido, Francesca; Di Franco, Gregorio; Di Giuseppe, Matteo; Di Saverio, Salomone; Diaz, Jose J; Diaz-Peña, Patricia; Dickson, Kathryn E; Diez-Alonso, Manuel M; Dixon, Jan R; Doe, Matthew J; Dolores Del Toro, M; Dousset, Bertrand; Doussot, Alexandre; Drake, Frederick T; Drake, Thomas D; Duchateau, Nicolas; Duff, Sarah; Duffy, John P; Dunne, Declan Fj; Dunne, Naomi Jm; Dunning, Joel; Duque-Mallen, Victoria; Durst, Alexander Ze; Durán-Muñoz-Cruzado, Virginia M; Dziakova, Jana; DÃaz Pérez, David; DÃaz-García, Alberto; Eardley, Nicola J; Edwards, John G; Egan, Bridget; Egan, Richard; El Kassas, Mohamed; El Youzouri, Hanan; El-Ali, Abess; Elfallal, Ahmed H; Elfeki, Hossam; Elfiky, Mahmoud Ma; Elhadi, Muhammed; Eljareh, Mohammed; Elkadi, Hannah H; Elkady, Ramy; Elkhafeefi, Fatimah; Elliott, Jessie A; Elmore, Ugo; Elmoslemany, Tarek; Emile, Sameh H; Emmerson, Oliver; Emslie, Katy M; Endorf, Frederick W; Enemosah, Ibrahim; Engel, Jamie L; English, Camilla; English, William; Enjuto, Diego T; Erridge, Simon; Escartin, Jorge; Estaire-Gomez, Mercedes; Etchill, Eric W; Evans, Jessica; Evans, Jonathan P; Evans, Luke; Exley, Rebecca; Fabbri, Nicoló; Fahey, Brian A; Falco, Giuseppe; Familiari, Pietro; Fancellu, Alessandro; Faria, Carlos S; Farik, Shebani; Farrell, Tony; Fehervari, Matyas; Fell, Adam; Feo, Carlo V; Ferguson, Henry Jm; Fernandez, Andres Garcia; Fernandez, Beatriz Dieguez; Fernandez-Camuñas, Angel; Fernández, Antonio J; Fernández-Martínez, María; Fernández-MarÃn, Reyes; Fernández-Pacheco, Borja Camacho; Ferrara, Francesco; Ferrari, Guglielmo; Ferrero, Simone; Findlay, Laura; Fiore, Marco; Fiori, Enrico; Fitzgerald, J Edward; Flatman, Michael; Flindall, Ian; Flor, Blas; Fonsi, Giovanni B; Font, Roser Farré; Fontana, Tommaso; Ford, David; Ford, Samuel; Forlani, Stefano; Fowler, Amy L; Francone, Elisa; Frattaruolo, Colomba; Fretwell, Kenneth R; Frio, Federico; Fructuoso, Lorena Sanchon; Fusai, Giuseppe K; Gagliano, Annalisa; Gagliardi, Filippo; Gahunia, Sukhpreet; Gaino, Francesca; Gala, Tanzeela; Galfrascoli, Elisa; Galimberti, Luca; Galindo Jara, Pablo; Gallagher, Phoebe; Galleano, Raffaele; Gallo, Gaetano; Galván-Pérez, Armando; Gammeri, Emanuele; Ganau, Mario; Garcia Galocha, Jose L; Garcia, Miguel Hernandez; Garcia-Ureña, Miguel Angel; Garcés-García, Raúl; Gardner, Anne; Garulli, Gianluca; Gascon-Ferrer, Isabel; Gattolin, Andrea; Gaujoux, Sebastien; Gentilli, Sergio; Georgiades, Fanourios; Ghanbari, Amir; Ghosh, Dhruv; Giacometti, Marco; Giblin, Anna-Victoria; Gilbert, Catherine; Gill, Charn K; Giménez, Clara; Giorgakis, Emmanouil; Gipponi, Manuel; Gisbertz, Suzanne S; Giuffrida, Maria Carmela; Glasbey, James C; Glen, Paul; Goatly, Giles; Gobatti, Davide; Godbole, Chintamani; Gohil, Kajal; Gomez-Rosado, Juan-Carlos; Gonullu, Emre; Gonzalez-De Miguel, Melania; Gonzalez-Gonzalez, Enrique; Gordini, Luca; Gracia, Isabel; Gracia-Roche, Carlos; Granieri, Stefano; Green, Susanna; Gregg, Anne; Griffiths, Ewen A; Grivon, Manuela; Grove, Thomas; Guaglio, Marcello; Guaitoli, Eleonora; Guariglia, Claudio A; Guglielmi, Alfredo; Guha, Soumya; Gujjuri, Rohan R; 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Hölzle, Frank; Iacob, Giulio; Iannone, Immacolata; Ibrahim, Mohamed Ah; Ibrahim, Sherif; Iovino, Domenico; Irvine, Esmee; Isik, Arda; Isolani, Simone M; Jafarova, Sevda; Jamil, Tahir; Jayaraju, Ullas; Jeganathan, Reuben; Jenkinson, Michael D; Jenner, Edward; Jenny, Hillary E; Jeyaretna, Deva S; Jiao, Long R; Jimenez-Higuera, Elisa; Jimeno, Jaime; Johnstone, Jack R; Jones, Andrew P; Jones, Gareth P; Jones, Mark; Jones, Robert P; Jonker, Pascal Kc; Joyce, Doireann P; Judkins, Nicholas; Jönsson, Maria L; Kaafarani, Haytham Ma; Kalavrezos, Nicholas; Kalidindi, Venugopala; Kalkat, Maninder; Kalkwarf, Kyle J; Kamal, Mona; Kamarajah, Sivesh K; Kamphues, Carsten; Kang, Chong; Kara, Yasin; Karam, Edward; Karim, Ahmed; Kashora, Florence; Kaushal, Manish V; Kavanagh, Dara O; Kearney, David; Keatley, James M; Keller, Deborah S; Khajuria, Apoorva; Khalefa, Mohamed A; Khan, Azam; Khan, Jim S; Khan, Umul; Khatri, Chetan; Kinnaman, Gabriel; Kinross, James; Kirmani, Bilal H; Kisiel, Aaron P; Kler, Aaron; 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Loubani, Mahmoud; Lowery, Aoife J; Lowy-Benoliel, Alejandro; Lozano, Saida Martel; Lucianetti, Alessandro; Luke, Louis; Lunevicius, Raimundas; Luney, Catriona R; Luraghi, Marco; Lye, George; Lázaro, André; Löffler, Markus W; Mabrouk, Islam; Macchi, Alberto; MacDonald, Luisa; Machairas, Nikolaos; Madonini, Marco; Magowan, Drew; Maia, Mariana Magalhães; Maisonneuve, Emeline; Majkowska, Agata; Majkowski, Lawrence; Mak, Jason; Malabarba, Stefano; Malerba, Michele; Mannan, Syed; Manson, Joanna; Mansuri, Ahmer; Mantoglu, Baris; Manu, Nichola; Maqsood, Afnan; Marano, Alessandra; Marchbank, Adrian; Marcos-Santos, Pablo; Mari, Giulio Maria; Mariani, Nicolò M; Marino Cosentino, Luigi Mp; Marino, Marco V; Marra, Angelo A; Marrano, Enrico; Marsh, Christopher L; Martin, Benjamin; Martin, Emmeline; Martin, Guy; Martin, Janet; Martin, Robert Cg; Martin-Albo, Lorena; Martinelli, Fabio; Martinez-German, Antonio; Martinez-Pinedo, Carlos; Martins, Ricardo; MartÃn-Román, Lorena; Martínez-dePaz, Fernando; Martínez-Pérez, Carolina; Marwan, Hisham; Marzi, Federica; Mashbari, Hassan N; Mateo-Sierra, Olga; Mathieu, Pierre; Matute-Najarro, Maria-Soledad; Maw, Andrew; Mazingi, Dennis; Mazzaferro, Vincenzo; McCanny, Andrew; McCluney, Simon J; McIntyre, Robert C; Mckay, Siobhan C; McKenzie, Katherine; McKevitt, Kevin L; McLarty, Nicola; McPherson, Iain; Meagher, Ashley D; Medina, Esther; Mediratta, Saniya; Medone, Marzia; Mehdi, Mohammad Q; Mehigan, Brian J; Mehra, Gautam; Mele, Simone; Melero-Cortés, Lidia; Mendoza-Moreno, Fernando; Meneghini, Simona; Mercante, Giuseppe; Merdrignac, Aude; Merola, Stephen; Metallidis, Symeon; Michel, Martin; Migliore, Marco; Mihanovic, Jakov; Miller, Douglas; Mills, Sarah J; Minaya-Bravo, Ana; Mingoli, Andrea; Minto, Gary; Mirabella, Antonello; Misra, Nikhil; Mithany, Reda H M; Mitrasinovic, Stefan; Miu, Victor; Moawad, Nader; Mochet, Sylvie; Modabber, Ali; Mohammad, Adam; Mohan, Helen M; Mohan, Midhun; Moir, John Ag; Moliner-Sánchez, Carmen; Mongelli, Francesco; Monson, John Rt; Monteiro, Joana M; Monteleone, Michela; Montella, Maria T; Montesinos, Cristina Soto; Montuori, Mauro; Moore, Rachel; Mora-Guzmán, Ismael; Morales, Dieter; Morales, Xavier; Morelli, Luca; Morelli, Lucia; Morgan, Richard; Morgom, Marwa M; Morris, Chris; Mortini, Pietro; Morton, Dion G; Mosca, Angelo; Moszkowicz, David; Motter, Dema; Moug, Susan; Moura, Francisco S; Muguerza, Jose M; Mukherjee, Samrat; Murphy, Suzanne H; Najdy, Manhal; Nakas, Apostolos; Namazov, Ilgar; Naredla, Pradyumna; Nasef, Emmhamed; Nassa, Heeam; Nath, Rahul; Naumann, David N; Navarro-Sánchez, Antonio; Nazarian, Scarlet; Neary, Paul C; Neely, David Ta; Negri, Giampiero; Nehra, Deepika; Neil-Dwyer, Jason; Nepogodiev, Dmitri; Neri, Jacopo; Newton, Katy; Ng-Kamstra, Joshua S; Ngu, Albert Wt; Nguyen, Truong A; Nikaj, Herald; Niquen, Milagros; Nita, George E; Nizami, Kulsoom; Nobile, Sara; Nogueiro, Jorge; Ntirenganya, Faustin; Nugent Iii, William C; Nugent, Michael; Nunes, Quentin M; Nygaard, Rachel M; Núñez, Jordi; O'Meara, Lindsay B; O'Neill, John R; Ocaña, Juan; Odeh, Abdulrahman; Okafor, Barbara U; Okechukwu, Valentine; Oliva-Mompean, Fernando; Oliveira, Ana; Ollat, Didier; Olson, Steven A; Omar, Omar M; Onos, Lavinia; Oo, Aung Y; Ormazabal, Pablo Collera; Osagie-Clouard, Liza; Osman, Khabab; Osorio, Alexander L; Ottolina, Jessica; Ourieff, Jared; Outani, Oumaima; Oyewole, Bankole; Ozben, Volkan; Pacheco-Sanchez, David; Pachl, Max J; Padilla-Valverde, David; Pai, Madhava; Paiella, Salvatore; Paisley, Samuel; Palini, Gianmarco; Palmeri, Matteo; Panahi, Pedram; Parente, Alessandro; Parlanti, Daniele; Parmar, Chetan; Parry, James T; Pascual, Angela; Pata, Francesco; Patel, Mahul; Patel, Panna K; Pathak, Abhijit; Patil, Sangram; Pattyn, Piet; Peckham-Cooper, Adam; Pedrazzani, Corrado; Pellino, Gianluca; Peluso, Chiara; Pereira, André; Pereira-Neves, António; Perez-Diaz, M D; Perivoliotis, Konstantinos; Perkins, Clare; Peros, Georgios; Perotto, Ornella; Perra, Teresa; Petrone, Patrizio; Pevidal, Ana Nogues; Pezzuto, Anna P; Phenix, George; Philp, Matthew M; Picazo, Sara; Picon-Rodriguez, Rafael; Piloni, Martina; Pingarrón-MartÃn, Lorena; Pinkney, Thomas D; Pinotti, Enrico; Pisanu, Adolfo; Pizzini, Paolo; Pockney, Peter; Podda, Mauro; Podolsky, Dina; Poggioli, Gilberto; Pollok, Joerg M; Pompili, Cecilia; Pontari, Michael; Porcu, Alberto; Potter, Ryan; Povey, Meical G; Poza, Alfredo Alonso; Price, Claire; Pruvot, François-René; Pujol-Muncunill, Roger; Puppo, Andrea; Pérez-González, Marta; Pérez-Saborido, Baltasar; Pérez-Sánchez, Luis E; Quante, Markus; Quintana-Villamandos, Begoña; Qureshi, Ali; Radenkovic, Dejan; Rajgor, Amarkumar D; Rakvin, Ivan; Ramallo-SolÃs, Irene; Ramcharan, Sean; Ramos, Diego; Ramos-Bonilla, Antonio; Ramos-De la Medina, Antonio; Ramzi, Joussi; Rao, Jagan N; Raptis, Dimitri A; Rathinam, Sridhar; Rausa, Emanuele; Ravaioli, Matteo; Ravindran, Sharanya; Raymond, Thomas; Razik, Aisha; Redfern, Jennifer; Reguera-Rosal, Julio; Rela, Mariam; Rey-Biel, Juan; Rey-Valcarcel, Cristina; Ribolla, Marta; Rice, Henry E; Richards, Tomos; Richmond, Michael; Ridgway, Paul F; Righini, Erminio; Rio-Gomez, Javier; Rivas, Ana Munoz; Riyat, Harjoat; Rizvi, Sana; Roberts, Keith; Roberts, Matthew; Robertson, Ronald; Robertson, Stuart; Robin-Valle, Alvaro; Rochon, Melissa; Rodriguez-Sanjuan, Juan C; Rogers, Luke J; Rojo, Mikel; Rollett, Rebecca A; Rolli, Luigi; Romano, Silvio; Romera, Jose L; Rooney, Siobhan M; Rosato, Francesco; Roslani, April C; Ross, Elizabeth; Ross, Howard; Rossborough, Catherine; Rottoli, Matteo; Roxo, Vanessa I; Rubio, Eduardo E; Ruiz, Carolina Castro; Ruiz, Manuel Losada; Ruiz-Grande, Fernando; Ruiz-Marin, Miguel; Ruiz-Martin, Irene; Ruiz-Soriano, María; Ruzzenente, Andrea; Ryan, Éanna J; Ryska, Ondrej; Saad, Abdel Rahman; Saeed, Samerah A; Saez, Carlos; Sagnotta, Andrea; Sahnan, Kapil; Sahni, Arun; Salama, Hiba A; Salamah, Abdulrauf A; Salem, Hosni Khairy; Salim, Ali; Sallam, Ibrahim; Salvia, Roberto; Samadov, Elgun; Sammarco, Giuseppe; 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Shalaby, Mostafa; Shane Lester, Madan Jha; Shankar, Sushma; Sharma, Neil; Shaw, Abigail V; Shaw, Richard; Sheel, Andrea Rg; Shehata, Sameh; Shenfine, Amy; Sheridan, Kelda; Sherief, Ahmed; Sherief, Mohamed; Sherif, Mohamed; Shinkwin, Michael; Shu, Sebastian; Siaw-Acheampong, Kwabena; Sica, Giuseppe S; Siddique, Muhammad Harris; Sileri, Pierpaolo; Simoes, Joana Ff; Singh, Abhinav; Singh, Aminder A; Singh, Rabindra P; Singh, Shailendra; Sinha, Deepti; Sinha, Sanjay; Siragusa, Leandro; Sivaprakasam, Rajesh; Sivayoganathan, Sriharan; Skelly, Brendan L; Smart, Neil J; Smillie, Robert; Smith, Andrew; Smith, Christopher; Smith, Claire; Smith, Henry G; Sochorova, Dana; Soggiu, Fiammetta; Sohail, Amir H; Sohrabi, Catrin; Solari, Francesca; Solli, Piergiorgio; Soreide, Kjetil; Spalding, Duncan R; Spinelli, Antonino; Spoletini, Domenico; Spriano, Giuseppe; Springford, Laurie R; Sravanam, Sanskrithi; Ssentongo, Anna E; Ssentongo, Paddy; Stanger, Sophie; Stavroulias, Dionisios; Steel, Ben; Steinkamp, Pieter J; Stella, Marco; Stevens, Kent A; Stewart, Grant D; Stewart, Robbie; Stringer, Sally; Stylianides, Nicholas A; Sulen, Nina; Sullivan, Tom Bb; Sundar, Sudha; Sundhu, Matthew; Suri, Avni; Syed, Arooj; Szatmary, Peter; Sánchez-Arteaga, Alejandro; Tabiri, Stephen; Tadross, Daniel; Taglietti, Lucio; Taher, Ahmed Sa; Tamimy, Muhammad S; Tang, Alethea M; Tansey, Rosamond; Tartaglia, Dario; Tawheed, Ahmed; Tayeh, Salim; Tebala, Giovanni D; Tejero-Pintor, Francisco J; Teles, Tobias; Testa, Valentina; Tewari, Nilanjana; Thaha, Mohamed A; Thoenissen, Philipp; Thomas, Amy J; Thomas, Kane; Thomin, Anne; Thrush, Jessica; Tierney, Sean; Tiwari, Abhinav; Toh, Simon; Toledo, Enrique; Tonini, Valeria; Torkington, Jared; Torquati, Alfonso; Torres, Antonio J; Torzilli, Guido; Totty, Joshua; Tourountzi, Paraskevi; Tousidonis, Manuel; Townend, Philip; Townsend, Catherine; Townshend, David N; Tripathi, Shiva S; Trompeter, Alex; Trompetto, Mario; Trotta, Francesco; Trout, Isobel M; Truant, Stéphanie; Trujillo-DÃaz, Jeancarlos; Tsoulfas, George; Tsoulfas, Georgios; Tucker, Sarah C; Turco, Celia; Turrado-Rodriguez, Victor; Turri, Giulia; Tustin, Harry; Tyler, Jayne; Tzedakis, Stylianos; Tzovaras, George; Ubhi, Harmony K; Uittenbogaart, Martine; Ullah, Ramzan; Urban, Shane; Urbani, Alessia; Usai, Antonella; Vaccarella, Gianpaolo; Valdes-Hernandez, Javier; Valsecchi, Luca; van Berge Henegouwen, Mark I; van der Plas, Willemijn Y; van Heinsbergen, Maarten; van Ramshorst, Gabrielle H; Vashisht, Rajiv; Vega, Viviana A; Velmahos, George C; Velopulos, Catherine G; Venkatesan, Gowtham S; Venn, Mary; Venn, Mary L; Vera-Mansilla, Cristina; Vergari, Roberto; Vescio, Giuseppina; Vidya, Raghavan; Vieira, Paula; Vijay, Vardhini; Vimalachandran, Dale; Violante, Tommaso; Viswanath, Yirupaiahgari Ks; Vivas, Alfredo A; Volpe, Anita; Vovola, Fernanda; Vulliamy, Paul; Vázquez-Fernández, Andrea; Wade, Ryckie G; Wadley, Martin S; Wall, Joshua Js; Wall, Rosemary; Wallwork, Kate; Walsh, Stewart; Walters, Andrew M; Ward, Alex; Warren, Oliver J; Warwick, David; Waseem, Saima; Weaver, Helen; Weerasinghe, Chamindri K; Wells, Fiona; Wen, Jiaxin; West, Raha; Whitehall, Emma; Wild, Laura; Wilkin, Richard Jw; Wilkins, Alex; Williams, Gethin; Williams, Katherine J; Williams, Matthew; Winnand, Philipp; Winter, Stuart C; Wong, Ken; Worku, Dawit; Wormald, Justin Cr; Wright, Franklin L; Wright, Naomi; Xyda, Souzana E; Yalamanchili, Seema; Yershov, Danylo; Yildiz, Alp; Young, Alastair L; Young, Richard; Youssef, Mina Mg; Yousuf, Farhat B; Yurttas, Can; Zadegan, Frederic; Zafar, Noman; Zakaria, Rasheed; Zambon, Martina; Zanini, Nicola; Zappa, Marco A; Zarate, Alba; Zerbib, Philippe; Zizzo, Maurizio; Zmora, Oded; Zonta, Sandro
BACKGROUND:The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. METHODS:This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. FINDINGS:This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28-2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65-3·22], p<0·0001), American Society of Anesthesiologists grades 3-5 versus grades 1-2 (2·35 [1·57-3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01-2·39], p=0·046), emergency versus elective surgery (1·67 [1·06-2·63], p=0·026), and major versus minor surgery (1·52 [1·01-2·31], p=0·047). INTERPRETATION:Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. FUNDING:National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
PMID: 32479829
ISSN: 1474-547x
CID: 4851402
