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Correction to: The Devil's in the Details: Discrepancy Between Biopsy Thickness and Final Pathology in Acral Melanoma

Lee, Ann Y; Friedman, Erica B; Sun, James; Potdar, Aishwarya; Daou, Hala; Farrow, Norma E; Farley, Clara R; Vetto, John T; Han, Dale; Tariq, Marvi; Shapiro, Richard; Beasley, Georgia; Contreras, Carlo M; Osman, Iman; Lowe, Michael; Zager, Jonathan S; Berman, Russell S
PMID: 33893602
ISSN: 1534-4681
CID: 4889162

Taking Care of the Puerto Rican Patient: Historical Perspectives, Health Status, and Health Care Access

Díaz, Débora H Silva; Garcia, Glenn; Clare, Camille; Su, Julia; Friedman, Erica; Williams, Renee; Vazquez, Juan; Sánchez, John Paul
Introduction:Hispanics are the largest minority group in the US at 18% of the population, of which Puerto Ricans are the second largest subgroup. Puerto Ricans have poorer health status than other US Hispanic and non-Hispanic populations. Thus, health care providers need to know about and distinguish the health care problems of Puerto Ricans to improve their health. Although there are some published curricula addressing how to provide health care to Hispanic populations, none address the specific needs of Puerto Ricans. Methods:We developed a 60-minute interactive workshop consisting of a PowerPoint presentation and case discussion aimed at increasing health care providers' knowledge and understanding of the historical perspective that led to Puerto Rican identity, health issues and disparities, and the health care access problems of mainland and islander Puerto Ricans. Evaluation consisted of pre- and postworkshop questionnaires. Results:There were a total of 64 participants with diverse ethnoracial identities including medical students, residents, faculty, physicians, researchers, administrators, and students/faculty from nursing, occupational therapy, genetic counseling, biomedical sciences, and social work programs. A comparison of pre- and postworkshop data showed a statistically significant increase in participants' confidence in meeting all learning objectives. Participants positively commented on the interactive nature of the workshop, the case discussion, and the historical perspective provided. Discussion:With the increasing migration of Puerto Ricans to the US mainland this module can uniquely improve the preparation of current and future health care providers to provide competent care to Puerto Rican patients.
PMCID:7549386
PMID: 33083536
ISSN: 2374-8265
CID: 4683932

The Devil's in the Details: Discrepancy Between Biopsy Thickness and Final Pathology in Acral Melanoma

Lee, Ann Y; Friedman, Erica B; Sun, James; Potdar, Aishwarya; Daou, Hala; Farrow, Norma E; Farley, Clara R; Vetto, John T; Han, Dale; Tariq, Marvi; Shapiro, Richard; Beasley, Georgia; Contreras, Carlo M; Osman, Iman; Lowe, Michael; Zager, Jonathan S; Berman, Russell S
PURPOSE/OBJECTIVE:We hypothesized that initial biopsy may understage acral lentiginous melanoma (ALM) and lead to undertreatment or incomplete staging. Understanding this possibility can potentially aid surgical planning and improve primary tumor staging. METHODS:A retrospective review of primary ALMs treated from 2000 to 2017 in the US Melanoma Consortium database was performed. We reviewed pathology characteristics of initial biopsy, final excision specimens, surgical margins, and sentinel lymph node biopsy (SLNB). RESULTS:We identified 418 primary ALMs (321 plantar, 34 palmar, 63 subungual) with initial biopsy and final pathology results. Median final thickness was 1.8 mm (range 0.0-19.0). There was a discrepancy between initial biopsy and final pathology thickness in 180 (43%) patients with a median difference of 1.6 mm (range 0.1-16.4). Final T category was increased in 132 patients (32%), including 47% of initially in situ, 32% of T1, 39% of T2, and 28% of T3 lesions. T category was more likely to be increased in subungual (46%) and palmar (38%) melanomas than plantar (28%, p = 0.01). Among patients upstaged to T2 or higher, 71% had ≤ 1-cm margins taken. Among the 27 patients upstaged to T1b or higher, 8 (30%) did not have a SLNB performed, resulting in incomplete initial staging. CONCLUSIONS:In this large series of ALMs, final T category was frequently increased on final pathology. A high index of suspicion is necessary for lesions initially in situ or T1 and consideration should be given to performing additional punch biopsies, wider margin excisions, and/or SLNB.
PMID: 32529271
ISSN: 1534-4681
CID: 4489782

The intriguing association between smoking and reduced melanoma risk

Thompson, J F; Friedman, E B
PMID: 31872423
ISSN: 1365-2133
CID: 4244132

Management of pigmented skin lesions during pregnancy

Friedman, Erica; Scolyer, Richard; Thompson, John
BACKGROUND:As a result of the rapidly changing hormonal milieu, changing or newly discovered pigmented skin lesions during pregnancy can be diagnostically challenging. It is important for GPs to be aware of the effect of gestational changes on pigment production and features that should raise concern. OBJECTIVE:The aim of this article is to provide an understanding of common changes that may occur in pigmented lesions during pregnancy, features that are of concern and the management of suspected melanoma in pregnant women. DISCUSSION:In pregnant women, changing naevi should be evaluated using conventional ABCDE melanoma diagnostic criteria, and suspicious lesions should not be attributed solely to a change in the hormonal milieu. In this population, diagnosed melanoma is probably best treated at a specialist centre.
PMID: 31476830
ISSN: 2208-7958
CID: 4068972

Management of pigmented skin lesions in childhood and adolescence

Friedman, Erica B; Scolyer, Richard A; Thompson, John F
BACKGROUND:Pigmented skin lesions in childhood and adolescence can be diagnostically challenging. It is important for general practitioners to be aware of the spectrum of benign, atypical and malignant pigmented lesions occurring in these patient groups and of features that should raise concern. OBJECTIVE:The aims of this article are to assist recognition of high-risk skin lesions encountered in childhood and adolescence and to provide an understanding of the features and management of suspected melanoma in this population. DISCUSSION:In children and adolescents, there exist a variety of congenital and acquired naevi and other pigmented skin lesions that can be diagnostically problematic. Additionally, conventional detection criteria for melanoma seen in adults are often not present in children and adolescents, making diagnosis more difficult. Melanoma, if diagnosed in these populations, should be treated at a specialist centre whenever possible.
PMID: 31370129
ISSN: 2208-7958
CID: 4038402

Appropriate excision margins for cutaneous melanomas

Thompson, John F; Friedman, Erica B
PMID: 31280970
ISSN: 1474-547x
CID: 3976322

Continuing and new roles for surgery in the management of patients with stage IV melanoma [Editorial]

Friedman, Erica B; Thompson, John F
PMCID:6122527
PMID: 30190929
ISSN: 2045-0893
CID: 3663802

When is surgery for metastatic melanoma still the most appropriate treatment option?

Friedman, Erica B; Ferguson, Peter M; Thompson, John F
PMID: 30071762
ISSN: 1744-8328
CID: 3242912

Correlation Between Surgical and Histologic Margins in Melanoma [Meeting Abstract]

Friedman, E. B.; Dodds, T.; Lo, S.; Ferguson, P.; Beck, M.; Scolyer, R.; Thompson, J. F.
ISI:000431188600458
ISSN: 1068-9265
CID: 3195042