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Reversible nucleophilic addition can lower the observed enantioselectivity in palladium-catalyzed allylic amination reactions with a variety of chiral ligands

Caminiti, Nicholas S.; Goodstein, Madison B.; Leibler, Isabelle N. -M.; Holtzman, Bryan S.; Jia, Zitong B.; Martini, Michael L.; Nelson, Nathaniel C.; Bunt, Richard C.
ISI:000362533900018
ISSN: 0040-4039
CID: 5525302

Investigation of the Electronic Origin of Asymmetric Induction in Palladium-Catalyzed Allylic Substitutions with Phosphinooxazoline (PHOX) Ligands by Hammett and Swain-Lupton Analysis of the C-13 NMR Chemical Shifts of the (pi-Allyl)palladium Intermediates

Armstrong, Paul B.; Dembicer, Elizabeth A.; DesBois, Andrew J.; Fitzgerald, Jay T.; Gehrmann, Janet K.; Nelson, Nathaniel C.; Noble, Amelia L.; Bunt, Richard C.
ISI:000309488500024
ISSN: 0276-7333
CID: 5525292