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Simulation of New York City's Ventilator Allocation Guideline During the Spring 2020 COVID-19 Surge
Walsh, B Corbett; Zhu, Jianan; Feng, Yang; Berkowitz, Kenneth A; Betensky, Rebecca A; Nunnally, Mark E; Pradhan, Deepak R
IMPORTANCE:The spring 2020 surge of COVID-19 unprecedentedly strained ventilator supply in New York City, with many hospitals nearly exhausting available ventilators and subsequently seriously considering enacting crisis standards of care and implementing New York State Ventilator Allocation Guidelines (NYVAG). However, there is little evidence as to how NYVAG would perform if implemented. OBJECTIVES:To evaluate the performance and potential improvement of NYVAG during a surge of patients with respect to the length of rationing, overall mortality, and worsening health disparities. DESIGN, SETTING, AND PARTICIPANTS:This cohort study included intubated patients in a single health system in New York City from March through July 2020. A total of 20 000 simulations were conducted of ventilator triage (10 000 following NYVAG and 10 000 following a proposed improved NYVAG) during a crisis period, defined as the point at which the prepandemic ventilator supply was 95% utilized. EXPOSURES:The NYVAG protocol for triage ventilators. MAIN OUTCOMES AND MEASURES:Comparison of observed survival rates with simulations of scenarios requiring NYVAG ventilator rationing. RESULTS:The total cohort included 1671 patients; of these, 674 intubated patients (mean [SD] age, 63.7 [13.8] years; 465 male [69.9%]) were included in the crisis period, with 571 (84.7%) testing positive for COVID-19. Simulated ventilator rationing occurred for 163.9 patients over 15.0 days, 44.4% (95% CI, 38.3%-50.0%) of whom would have survived if provided a ventilator while only 34.8% (95% CI, 28.5%-40.0%) of those newly intubated patients receiving a reallocated ventilator survived. While triage categorization at the time of intubation exhibited partial prognostic differentiation, 94.8% of all ventilator rationing occurred after a time trial. Within this subset, 43.1% were intubated for 7 or more days with a favorable SOFA score that had not improved. An estimated 60.6% of these patients would have survived if sustained on a ventilator. Revising triage subcategorization, proposed improved NYVAG, would have improved this alarming ventilator allocation inefficiency (25.3% [95% CI, 22.1%-28.4%] of those selected for ventilator rationing would have survived if provided a ventilator). NYVAG ventilator rationing did not exacerbate existing health disparities. CONCLUSIONS AND RELEVANCE:In this cohort study of intubated patients experiencing simulated ventilator rationing during the apex of the New York City COVID-19 2020 surge, NYVAG diverted ventilators from patients with a higher chance of survival to those with a lower chance of survival. Future efforts should be focused on triage subcategorization, which improved this triage inefficiency, and ventilator rationing after a time trial, when most ventilator rationing occurred.
PMCID:10556967
PMID: 37796499
ISSN: 2574-3805
CID: 5707982
Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery
Hinkelbein, Jochen; Andres, Janusz; Böttiger, Bernd W; Brazzi, Luca; De Robertis, Edoardo; Einav, Sharon; Gwinnutt, Carl; Kuvaki, Bahar; Krawczyk, Pawel; McEvoy, Matthew D; Mertens, Pieter; Moitra, Vivek K; Navarro-Martinez, Jose; Nunnally, Mark E; O'Connor, Michael; Rall, Marcus; Ruetzler, Kurt; Schmitz, Jan; Thies, Karl; Tilsed, Jonathan; Zago, Mauro; Afshari, Arash
INTRODUCTION/BACKGROUND:Cardiac arrest in the operating room is a rare but potentially life-threatening event with mortality rates of more than 50%. Contributing factors are often known, and the event is recognised rapidly as patients are usually under full monitoring. This guideline covers the perioperative period and is complementary to the European Resuscitation Council (ERC) guidelines. MATERIAL AND METHODS/METHODS:The European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery jointly nominated a panel of experts to develop guidelines for the recognition, treatment and prevention of cardiac arrest in the perioperative period. A literature search was conducted in MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials. All searches were restricted to publications from 1980 to 2019 inclusive and to the English, French, Italian and Spanish languages. The authors also contributed individual, independent literature searches. RESULTS:This guideline contains background information and recommendation for the treatment of cardiac arrest in the operating room environment, and addresses controversial topics such as open chest cardiac massage (OCCM), resuscitative endovascular balloon occlusion (REBOA) and resuscitative thoracotomy, pericardiocentesis, needle decompression and thoracostomy. CONCLUSION/CONCLUSIONS:Successful prevention and management of cardiac arrest during anaesthesia and surgery requires anticipation, early recognition and a clear treatment plan. The ready availability of expert staff and equipment must also be taken into consideration. Success not only depends on medical knowledge, technical skills and a well organised team using crew resource management but also on an institutional safety culture embedded in everyday practice through continuous education, training and multidisciplinary co-operation.
PMID: 37218626
ISSN: 1365-2346
CID: 5543692
Revising the Process and Structure of the Society of Critical Care Medicine Guidelines Toward a Living Guideline Model
Nunnally, Mark E; Dager, William E; Patel, Hariyali; Al-Hazzani, Waleed; Nadkarni, Vinay M; Kane-Gill, Sandra L
PMID: 37707376
ISSN: 1530-0293
CID: 5593812
Cardiac arrest in the perioperative period: a consensus guideline for identification, treatment, and prevention from the European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery
Hinkelbein, Jochen; Andres, Janusz; Böttiger, Bernd W; Brazzi, Luca; De Robertis, Edoardo; Einav, Sharon; Gwinnutt, Carl; Kuvaki, Bahar; Krawczyk, Pawel; McEvoy, Matthew D; Mertens, Pieter; Moitra, Vivek K; Navarro-Martinez, Jose; Nunnally, Mark E; O Connor, Michael; Rall, Marcus; Ruetzler, Kurt; Schmitz, Jan; Thies, Karl; Tilsed, Jonathan; Zago, Mauro; Afshari, Arash
INTRODUCTION/BACKGROUND:Cardiac arrest in the operating room is a rare but potentially life-threatening event with mortality rates of more than 50%. Contributing factors are often known, and the event is recognised rapidly as patients are usually under full monitoring. This guideline covers the perioperative period and is complementary to the European Resuscitation Council guidelines. MATERIAL AND METHODS/METHODS:The European Society of Anaesthesiology and Intensive Care and the European Society for Trauma and Emergency Surgery jointly nominated a panel of experts to develop guidelines for the recognition, treatment, and prevention of cardiac arrest in the perioperative period. A literature search was conducted in MEDLINE, EMBASE, CINAHL and the Cochrane Central Register of Controlled Trials. All searches were restricted to publications from 1980 to 2019 inclusive and to the English, French, Italian and Spanish languages. The authors also contributed individual, independent literature searches. RESULTS:This guideline contains background information and recommendation for the treatment of cardiac arrest in the operating room environment, and addresses controversial topics such as open chest cardiac massage, resuscitative endovascular balloon occlusion and resuscitative thoracotomy, pericardiocentesis, needle decompression, and thoracostomy. CONCLUSIONS:Successful prevention and management of cardiac arrest during anaesthesia and surgery requires anticipation, early recognition, and a clear treatment plan. The ready availability of expert staff and equipment must also be taken into consideration. Success not only depends on medical knowledge, technical skills and a well-organised team using crew resource management, but also on an institutional safety culture embedded in everyday practice through continuous education, training, and multidisciplinary co-operation.
PMID: 37430174
ISSN: 1863-9941
CID: 5537502
Guidelines and principles for the care of the cardiothoracic transplant patient in the intensive care unit
Nurok, Michael; Nunnally, Mark E; O'Connor, Michael; Pierson, Richard N; Baran, David A; Harper, Michael D; Malinoski, Darren; El Banayosy, Aly; Orija, Abiodun; Hall, Shelley; Edelman, Jeffrey D; Sundt, Thoralf M; Levine, Deborah; Kobashigawa, Jon; Nelson, David
Heart and lung transplant recipients require care provided by clinicians from multiple different specialties, each contributing unique expertise and perspective. The period the patient spends in the intensive care unit is one of the most critical times in the perioperative trajectory. Various organizational models of intensive care exist, including those led by intensivists, surgeons, transplant cardiologists, and pulmonologists. Coordinating timely efficient intensive care is an essential and logistically difficult goal. The present work product of the American Society of Transplantation's Thoracic and Critical Care Community of Practice, Critical Care Task Force outlines operational guidelines and principles that may be applied in different organizational models to optimize the delivery of intensive care for the cardiothoracic organ recipient.
PMID: 36964943
ISSN: 1399-0012
CID: 5462962
Nationwide Clinical Practice Patterns of Anesthesiology Critical Care Physicians-A Survey to Members of the Society of Critical Care Anesthesiologists
Shaefi, Shahzad; Pannu, Ameeka; Mueller, Ariel L; Flynn, Brigid; Evans, Adam; Jabaley, Craig S; Mladinov, Domagoj; Wall, Michael; Siddiqui, Shahla; Douin, David J; Boone, M Dustin; Monteith, Erika; Abalama, Vivian; Nunnally, Mark E; Cobas, Miguel; Warner, Matthew A; Stevens, Robert D
BACKGROUND:Despite the growing contributions of critical care anesthesiologists to clinical practice, research, and administrative leadership of intensive care units (ICUs), relatively little is known about the subspecialty-specific clinical practice environment. An understanding of contemporary clinical practice is essential to recognize the opportunities and challenges facing critical care anesthesia, optimize staffing patterns, assess sustainability and satisfaction, and strategically plan for future activity, scope, and training. This study surveyed intensivists who are members of the Society of Critical Care Anesthesiologists (SOCCA) to evaluate practice patterns of critical care anesthesiologists, including compensation, types of ICUs covered, models of overnight ICU coverage, and relationships between these factors. We hypothesized that variability in compensation and practice patterns would be observed between individuals. METHODS:Board-certified critical care anesthesiologists practicing in the United States were identified using the SOCCA membership distribution list and invited to take a voluntary online survey between May and June 2021. Multiple-choice questions with both single- and multiple-select options were used for answers with categorical data, and adaptive questioning was used to clarify stem-based responses. Respondents were asked to describe practice patterns at their respective institutions and provide information about their demographics, salaries, effort in ICUs, as well as other activities. RESULTS:A total of 490 participants were invited to take this survey, and 157 (response rate 32%) surveys were completed and analyzed. The majority of respondents were White (73%), male (69%), and younger than 50 years of age (82%). The cardiothoracic/cardiovascular ICU was the most common practice setting, with 69.5% of respondents reporting time working in this unit. Significant variability was observed in ICU practice patterns. Respondents reported spending an equal proportion of their time in clinical practice in the operating rooms and ICUs (median, 40%; interquartile range [IQR], 20%-50%), whereas a smaller proportion-primarily those who completed their training before 2009-reported administrative or research activities. Female respondents reported salaries that were $36,739 less than male respondents; however, this difference was not statistically different, and after adjusting for age and practice type, these differences were less pronounced (-$27,479.79; 95% confidence interval [CI], -$57,232.61 to $2273.03; P = .07). CONCLUSIONS:These survey data provide a current snapshot of anesthesiology critical care clinical practice patterns in the United States. Our findings may inform decision-making around the initiation and expansion of critical care services and optimal staffing patterns, as well as provide a basis for further work that focuses on intensivist satisfaction and burnout.
PMID: 35950751
ISSN: 1526-7598
CID: 5287072
A survey of intensive care unit models in cardiothoracic transplantation at high-volume centers [Letter]
Nurok, Michael; Nunnally, Mark E; Gill, George; O'Connor, Michael; Harper, Michael; Edelman, Jeffrey; Orija, Abiodun; Banayosy, Aly El; Malinoski, Darren; Sundt, Thor; Baran, David A; Levine, Deborah; Hall, Shelley; Kobashigawa, Jon; Nelson, David
PMID: 36630254
ISSN: 1399-0012
CID: 5419052
Shape Matters: A Neglected Feature of Medication Safety : Why Regulating the Shape of Medication Containers Can Improve Medication Safety
Bitan, Yuval; Nunnally, Mark E
This paper aims to highlight how to reduce medication errors through the implementation of human factors science to the design features of medication containers. Despite efforts to employ automation for increased safety and decreased workload, medication administration in hospital wards is still heavily dependent on human operators (pharmacists, nurses, physicians, etc.). Improving this multi-step process requires its being studied and designed as an interface in a complex socio-technical system. Human factors engineering, also known as ergonomics, involves designing socio-technical systems to improve overall system performance, and reduces the risk of system, and in particular, operator, failures. The incorporation of human factors principles into the design of the work environment and tools that are in use during medication administration could improve this process. During periods of high workload, the cognitive effort necessary to work through a very demanding process may overwhelm even expert operators. In such conditions, the entire system should facilitate the human operator's high level of performance. Regarding medications, clinicians should be provided with as many perceptual cues as possible to facilitate medication identification. Neglecting the shape of the container as one of the features that differentiates between classes of medications is a lost opportunity to use a helpful characteristic, and medication administration failures that happen in the absence of such intentional design arise from "designer error" rather than "user error". Guidelines that define a container's shape for each class of medication would compel pharmaceutical manufacturers to be compatible and would eliminate the confusion that arises when a hospital changes the supplier of a given medication.
PMID: 36586046
ISSN: 1573-689x
CID: 5409782
The Next Next Wave: How Critical Care Might Learn From COVID in Responding to the Next Pandemic
Tung, Avery; Dalton, Allison; Hastie, Jonathan; Jabaley, Craig S; Mittel, Aaron M; Nunnally, Mark E; Siddiqui, Shahla
PMID: 36269981
ISSN: 1526-7598
CID: 5352562
Mechanical circulatory support in the intensive care unit
Sommer, Philip; Nunnally, Mark
PMID: 35993668
ISSN: 1537-1913
CID: 5331492