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Microvascular free tissue transfer in organ transplantation patients: is it safe?

Lee, Anh B; Dupin, Charles L; Colen, Lawrence; Jones, Neil F; May, James W; Chiu, Ernest S
BACKGROUND:Traditionally, organ transplantation has been synonymous with patients with poor prognosis and outcome. Surgeons felt that the risks posed by immunosuppressive drugs outweighed the benefits of non-life-threatening procedures. With the enormous advances in the field of organ transplantation, a growing number of transplant patients present for a variety of surgical procedures. The objective of this report was to study the surgical outcome of organ transplantation patients who required reconstructive surgery using free tissue transfer. METHODS:A multicenter retrospective study was conducted on organ transplant patients who underwent elective microvascular free flap procedures. Patient chart review included cause of organ failure, medications, reconstruction site, flap choice, days hospitalized, complications, and outcome. RESULTS:Five independent medical centers participated in the study. Nineteen organ transplant patients required free flaps. Free flaps were used to reconstruct a variety of surgical defects, including breast, head and neck, and upper and lower extremities. There were no flap losses. Flaps used included musculocutaneous (n = 13), fasciocutaneous (n = 5), and osteocutaneous (n = 1) free flaps. Hospital length of stay ranged from 3 to 17 days. Complications included loss of skin graft, suture line dehiscence, and hematoma formation. Delayed wound healing was observed in two patients. CONCLUSIONS:In the properly selected patient, microvascular free tissue transfer can be performed safely and with acceptable surgical outcome. Contrary to popular belief, delayed wound healing from immunosuppressive agents was uncommon. Free tissue transfer in healthy organ transplant patients can be considered in reconstructive surgery decision making.
PMID: 18520886
ISSN: 1529-4242
CID: 5682042

Breast reconstruction with perforator flaps (Plastic and Reconstructive Surgery (2007) 120, (1) DOI: 10.1097/01.prs.0000256044.66107.a6))

Granzow, Jay W.; Levine, Joshua L.; Chiu, Ernest S.; LoTempio, Maria M.; Allen, Robert J.
SCOPUS:43149092242
ISSN: 0032-1052
CID: 5681972

Use of autologous fat for hemostasis during microvascular anastomosis repair

Chiu, Ernest S; Arya, Jyoti; Allen, Robert J Jr; Allen, Robert J Sr
PMID: 19050503
ISSN: 1529-4242
CID: 169976

Free flap monitoring using skin temperature strip indicators: adjunct to clinical examination

Chiu, Ernest S; Altman, Andrew; Allen, Robert J Jr; Allen, Robert J Sr
PMID: 18971690
ISSN: 1529-4242
CID: 169977

Anterior and middle cranial fossa skull base reconstruction using microvascular free tissue techniques: surgical complications and functional outcomes

Chiu, Ernest S; Kraus, Dennis; Bui, Duc T; Mehrara, Babak J; Disa, Joseph J; Bilsky, Mark; Shah, Jatin P; Cordeiro, Peter G
Surgical ablation for oncologic disease requiring skull base resection can result in both facial disfigurement and a complex wound defect with exposed orbital content, oral cavity, bone, and dural lining. Inadequate reconstruction can result in brain abscesses, meningitis, osteomyelitis, visual disturbances, speech impairment, and altered oral intake. This study assesses the functional outcomes of patients who undergo anterior and middle cranial fossa skull base reconstruction using microsurgical free tissue transfer techniques. Using a prospectively maintained database, a 10-year, single institution retrospective chart review was performed on patients who had surgery for anterior and middle cranial base tumor resections. The type of resection, reconstruction method, complication rate, and functional outcomes were reviewed. From 1992 to 2003, 70 patients (49 men, 21 women) with a mean age of 54 (age 6-78) underwent anterior and middle cranial skull base tumor resection and reconstruction. The patients were divided into the following groups: maxillectomy with orbital content preservation (n = 21), orbitomaxillectomy with palatal preservation (n = 26), and orbitomaxillectomy with palatal resection (n = 23). The average length of hospital stay was 12.6 days. The vertical rectus abdominis myocutaneous flap was used in the majority of cases to correct midface defects. Two flaps required emergent re-exploration; however, there were no flap failures. Early and late postoperative complications were investigated. Cerebrospinal fluid was observed infrequently (7%) and did not require additional surgical intervention. Intracranial abscesses were encountered rarely (1.4%). Patients who had maxillectomy with orbital preservation and reconstruction had minor ophthalmologic eyelid changes that occurred frequently. Patients who required palatal reconstruction had a normal or intelligible speech (93%) and unrestricted or soft diet (88%). Using a multidisciplinary surgical team approach, there is an increasing role for reconstruction of complex oncologic midface resection defects using microvascular surgical techniques. Early/late complications and functional problems after anterior cranial base resections are uncommon when free tissue transfer is used concomitantly.
PMID: 18434825
ISSN: 0148-7043
CID: 169978

Discussion of 'Transverse thoracodorsal artery perforator flaps: experience with 31 free flaps' [Comment]

Chiu, Ernest S; Bravo, Francisco G; Siebert, John W
PMID: 18083086
ISSN: 1748-6815
CID: 94725

Double-pedicle abdominal perforator free flaps for unilateral breast reconstruction: new horizons in microsurgical tissue transfer to the breast

Chiu, Ernest S.; Allen, Robert J.
SCOPUS:34347240975
ISSN: 1748-6815
CID: 5681922

Ankyloglossum superius syndrome: diagnosis and surgical management [Case Report]

Bolling, Robert P; Sabeeh, Vas; Stewart, Joel Mel Jr; Newsome, R Edward; Chiu, Ernest S; Moses, Michael H
Ankyloglossum superius (or ankyloglossia superior) is a rare congenital craniofacial condition characterized by tongue tip adherence to the hard palate and associated limb abnormalities. There have been few reports of this condition in the literature. We present a patient with ankyloglossum superius syndrome and discuss diagnosis and surgical management.
PMID: 17912091
ISSN: 1049-2275
CID: 169979

Endoscopic forehead rejuvenation: I. Limitations, flaws, and rewards [Letter]

Chiu, Ernest S; Baker, Daniel C
PMID: 17312532
ISSN: 1529-4242
CID: 169980

Congenital breast deformity reconstruction using perforator flaps [Case Report]

Gautam, Abhinav K; Allen, Robert J Jr; LoTempio, Maria M; Mountcastle, Timothy S; Levine, Joshua L; Allen, Robert J; Chiu, Ernest S
BACKGROUND: Congenital breast deformities such as Poland syndrome, unilateral congenital hypoplasia, tuberous breast anomaly, and amastia pose a challenging plastic surgical dilemma. The majority of patients are young, healthy individuals who seek esthetic restoration of their breast deformities. Currently, both implant and autologous reconstructive techniques are used. This study focuses on our experience with congenital breast deformity patients who underwent reconstruction using a perforator flap. METHODS: From 1994 to 2005, a retrospective chart review was performed on women who underwent breast reconstruction using perforator flaps to correct congenital breast deformities and asymmetry. Patient age, breast deformity type, perforator flap type, flap volume, recipient vessels, postoperative complications, revisions, and esthetic results were determined. RESULTS: Over an 11-year period, 12 perforator flaps were performed. All cases were for unilateral breast deformities. The patients ranged from 16 to 43 years of age. Six patients had undergone previous correctional surgeries. Eight (n = 8) flaps were used for correction of Poland syndrome and its associated chest wall deformities. Four (n = 4) flaps were used for correction of unilateral breast hypoplasia. In all cases, the internal mammary vessels were the recipient vessels of choice. No flaps were lost. No vein grafts were used. All patients were discharged on the fourth postoperative day. Complications encountered included seroma, hematoma, and nipple malposition. Revisional surgery was performed in 30% of the cases. Esthetic results varied from poor to excellent. CONCLUSIONS: Perforator flaps are an acceptable choice for patients with congenital breast deformities seeking autologous breast reconstruction. Deep inferior epigastric artery (DIEP) or superficial inferior epigastric artery (SIEA) flaps are performed when adequate abdominal tissue is available; however, many young patients have inadequate abdominal tissue, thus a GAP flap can be used. Perforator flaps are a safe, reliable surgical technique. In the properly selected patient, donor-site morbidity and functional compromise are minimized, improved self-esteem is noted, postoperative pain is decreased, and excellent long-term esthetic results can be achieved
PMID: 17413874
ISSN: 0148-7043
CID: 73213