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Use of the double-bladed scalpel in peripheral margin control of dermatofibrosarcoma protuberans [Case Report]
Moossavi, M; Alam, M; Ratner, D
BACKGROUND:The double-bladed scalpel previously has not been cited in the published literature for use in Mohs micrographic surgery. OBJECTIVE:To allow for maximum tissue conservation and greatest possible intraoperative efficiency for peripheral margin control of a massive tumor. METHODS:We describe the use of the double-bladed scalpel during Mohs surgery for peripheral margin control of a large dermatofibrosarcoma protuberans (DFSP). RESULTS AND CONCLUSION/CONCLUSIONS:While not necessary for the majority of routine Mohs cases, utilization of the double-bladed scalpel may be timesaving, especially when used for peripheral margin control of a massive tumor.
PMID: 10848948
ISSN: 1076-0512
CID: 3183102
Perineural spread of basal cell carcinomas treated with Mohs micrographic surgery
Ratner, D; Lowe, L; Johnson, T M; Fader, D J
BACKGROUND:Perineural spread is a well-documented feature of cutaneous tumors and may portend a more aggressive course. The incidence of perineural invasion in basal cell carcinoma (BCC) is reportedly 1%. The authors sought to determine whether perineural spread occurs more commonly than previously thought. METHODS:The authors prospectively evaluated 434 patients with BCC treated with Mohs surgery, assessing the presence or absence of perineural inflammation and invasion in tumors requiring more than one stage of surgery. They also documented the demographic features, clinical characteristics, histologic subtype, and operative data in each case. RESULTS:Seventy-eight BCCs required more than one stage of Mohs surgery. Perineural inflammation, perineural tumor invasion, or both were present in 29 of the 78 tumors (37%), or 6.7% of all 434 prospectively evaluated cases. Twenty-one of the 78 tumors (26.9%) exhibited perineural inflammation, 3 (3.8%) demonstrated perineural invasion, and 5 (6.4%) exhibited both. Tumors with perineural invasion required 5.3 surgical stages on average for clearance, in contrast to tumors without perineural invasion, which required 2.2 stages. Tumors with perineural inflammation, inflammation plus tumor invasion, and invasion alone were, respectively, 138%, 149%, and 194% greater in area preoperatively than tumors without perineural involvement, and their mean defect areas after Mohs surgery were, respectively, 151%, 121%, and 605% larger than those of tumors without perineural involvement. CONCLUSIONS:The incidence of perineural invasion among cases of BCC appears higher than previously recognized. Tumor aggressiveness appears to correlate with the presence of perineural invasion. Surgery with horizontal frozen-section margin control enables easy detection of perineural involvement and should therefore be strongly considered for the treatment of high risk BCC patients.
PMID: 10738219
ISSN: 0008-543x
CID: 3183082
Principles of CO2/erbium laser safety
Fader, D J; Ratner, D
BACKGROUND:There are a variety of potential hazards with laser technology. METHODS:A review of the literature. OBJECTIVE:To summarize the potential hazards of CO2 and erbium laser technologies and the safety guidelines and equipment developed to minimize them. RESULTS:Laser hazards can be divided into the following categories: mechanical, environmental, macrobiologic, microbiologic, and iatrogenic. CONCLUSION/CONCLUSIONS:At the conclusion of this learning activity, the reader should be able to discuss the mechanical, environmental, macrobiologic, microbiologic, and iatrogenic hazards of resurfacing laser technology, the literature cited to support current safety guidelines, and the equipment developed to promote laser safety.
PMID: 10759800
ISSN: 1076-0512
CID: 3183092
Lymphoscintigraphy, sentinel lymph node biopsy, and Mohs micrographic surgery in the treatment of merkel cell carcinoma - Commentary [Editorial]
Ratner, D
ISI:000084578700010
ISSN: 1076-0512
CID: 3183682
The uses of digital photography in dermatology
Ratner, D; Thomas, C O; Bickers, D
Digital photography is a powerful tool that is transforming the specialty of dermatology by integrating patient and practice management. The fundamentals of digital imaging are discussed, and an approach to the selection of a digital camera and its associated hardware and software is provided. The applications of this technology to patient and practice management are addressed, and the ethical implications of digital tampering are also discussed.
PMID: 10534639
ISSN: 0190-9622
CID: 3183072
PTCH mutations in squamous cell carcinoma. [Meeting Abstract]
Lee, PK; Ping, XL; Zhang, H; Wu, XL; Chen, FF; Zhang, MJ; Silvers, DN; Ratner, D; Peacocke, M; Tsou, HC
ISI:000082879800335
ISSN: 0002-9297
CID: 3183662
Cutaneous laser resurfacing
Ratner, D; Tse, Y; Marchell, N; Goldman, M P; Fitzpatrick, R E; Fader, D J
UNLABELLED:Cutaneous resurfacing with the new generation of carbon dioxide and erbium lasers has recently come into favor for the treatment of facial rhytides, photodamage, and scarring. The precise control of these resurfacing lasers over the extent of tissue vaporization minimizes thermal damage to the skin while maximizing therapeutic efficacy. Proper use of resurfacing lasers is contingent upon a complete understanding of their clinical, histologic, and ultrastructural effects, as well as an appreciation of the principles of laser safety. An organized approach to the preoperative, intraoperative, and postoperative management of the patient undergoing laser resurfacing will be provided, including a discussion of prevention and treatment of postoperative side effects and complications. (J Am Acad Dermatol 1999;41:365-89.) LEARNING OBJECTIVE/OBJECTIVE:At the conclusion of this learning activity, participants should be familiar with the clinical, histologic, and ultrastructural effects of resurfacing lasers and be able to discuss the preoperative, intraoperative, and postoperative management of patients undergoing laser resurfacing.
PMID: 10459111
ISSN: 0190-9622
CID: 3183062
Histological comparison of postoperative wound care regimens for laser resurfacing in a porcine model - Commentary [Editorial]
Ratner, D
ISI:000080447600016
ISSN: 1076-0512
CID: 3183652
Role of the p53 and PTCH genes in the development of basal cell carcinoma [Meeting Abstract]
Yao, Y; Ratner, D; Zhang, H; Peacocke, M; Tsou, H
ISI:000079495800594
ISSN: 0022-202x
CID: 3183642
P53 immunohistochemical expression in early posttransplant-associated malignant and premalignant cutaneous lesions - Commentary [Editorial]
Ratner, D
ISI:000078531100005
ISSN: 1076-0512
CID: 3183632