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MDHAQ/RAPID3 scores in patients with osteoarthritis are similar to or higher than in patients with rheumatoid arthritis: a cross-sectional study from current routine rheumatology care at four sites

El-Haddad, Carlos; Castrejon, Isabel; Gibson, Kathryn A; Yazici, Yusuf; Bergman, Martin J; Pincus, Theodore
Objective/UNASSIGNED:To compare patients with a primary diagnosis of osteoarthritis (OA) versus rheumatoid arthritis (RA) for scores on a patient self-report MDHAQ/RAPID3 (Multidimensional Health Assessment Questionnaire/Routine Assessment of Patient Index Data 3), and for physician global assessment (DOCGL). Methods/UNASSIGNED:All patients with all diagnoses complete an MDHAQ/RAPID3 at all routine rheumatology visits in the waiting area before seeing a rheumatologist at four sites, one in Australia and three in the USA. The two-page MDHAQ includes 0-10 scores for physical function (in 10 activities), pain and patient global assessment [on 0-10 visual analogue scales (VAS)], compiled into a 0-30 RAPID3, as well as fatigue and self-report painful joint count scales. Rheumatologists estimate a 0-10 DOCGL VAS. Demographic, MDHAQ/RAPID3 and DOCGL data from a random visit were compared in patients with RA versus patients with OA using multivariate analysis of variance, adjusted for age, disease duration and formal education level. Results/UNASSIGNED:Median RAPID3 was higher in OA versus RA at all four sites (11.7-16.8 vs 6.2-11.8) (p<0.001 at three sites). Median DOCGL in OA versus RA was 5 vs 4, 4 vs 3.7, 2.2 vs 2.5 and 2 vs 1. Patterns were similar for individual RAPID3 items, fatigue and painful joint scales, and in stratified analyses of patients aged 55-70. Conclusion/UNASSIGNED:Patient MDHAQ/RAPID3 and physician DOCGL indicate similar or higher disease burden in OA versus RA. Routine MDHAQ/RAPID3 allows direct comparisons of the two diseases. The findings suggest possible revision of current clinical and public policy views concerning OA.
PMCID:5708309
PMID: 29225915
ISSN: 2056-5933
CID: 2837642

COMPARATIVE EFFECTIVENESS OF SECUKINUMAB AND GOLIMUMAB IN ANKYLOSING SPONDYLITIS ASSESSED BY MATCHING-ADJUSTED INDIRECT COMPARISON USING PIVOTAL PHASE 3 CLINICAL TRIAL DATA [Meeting Abstract]

Maksymowych, W; Choy, E; Yazici, Y; Walsh, J; Thom, H; Kalyvas, C; Fox, T; Gandhi, K; Jugl, S
ISI:000413181403884
ISSN: 1468-2060
CID: 2790132

M-DAS28, DAS28 (CRP) AND RAPID3 SCORES AT BASELINE ARE GOOD PREDICTORS OF RADIOGRAPHIC DISEASE PROGRESSION AT 1 AND 2 YEARS: DATA FROM THE AMPLE TRIAL [Meeting Abstract]

Keystone, E; Ahmad, H; Yazici, Y; Muratti, E; Ye, J; Bergman, M
ISI:000413181400625
ISSN: 1468-2060
CID: 2790232

A DESCRIPTIVE ANALYSIS OF REAL-WORLD TREATMENT PATTERNS IN A TURKISH RHEUMATOLOGY POPULATION THAT CONTINUED INNOVATOR INFLIXIMAB (REMICADE) THERAPY OR SWITCHED TO BIOSIMILAR INFLIXIMAB [Meeting Abstract]

Yazici, Y; Xie, L; Ogbomo, A; Parenti, D; Goyal, K; Teeple, A; Ellis, L; Simsek, I
ISI:000413181402469
ISSN: 1468-2060
CID: 2790182

A DESCRIPTIVE ANALYSIS OF REAL-WORLD TREATMENT PATTERNS OF INNOVATOR INFLIXIMAB (REMICADE) AND BIOSIMILAR INFLIXIMAB IN A TREATMENT NAIVE TURKISH RHEUMATOLOGIC DISEASE POPULATION [Meeting Abstract]

Yazici, Y; Xie, L; Ogbomo, A; Parenti, D; Goyal, K; Teeple, A; Ellis, L; Simsek, I
ISI:000413181401611
ISSN: 1468-2060
CID: 2790192

INFLUENCE OF ETHNICITY ON CLINICAL PAIN IN PATIENTS WITH OSTEOARTHRITIS VERSUS RHEUMATOID ARTHRITIS: CONTRIBUTION OF LEVEL OF EDUCATION AND DEPRESSION [Meeting Abstract]

Castrejon, I; Chua, J; Block, JA; Bradley, LA; Yazici, Y; Shakoor, N
ISI:000413181402802
ISSN: 1468-2060
CID: 2790152

REMISSION ACCORDING TO RAPID3 (ROUTINE ASSESSMENT OF PATIENT INDEX DATA 3) IN PATIENTS WITH RHEUMATOID ARTHRITIS: A CROSS-SECTIONAL STUDY FROM ROUTINE CARE AT 3 USA SITES [Meeting Abstract]

Castrejon, I; Bergman, MJ; Gibson, KA; Yazici, Y; Block, JA; Pincus, T
ISI:000413181403410
ISSN: 1468-2060
CID: 2790142

Structural Damage in Patients with Very Early RA Is Predicted with Clinical Measures of Baseline Disease Activity: DAS28 (CRP), SDAI, M-DAS28 and RAPID3 but Not CDAI [Meeting Abstract]

Keystone, Edward C; Ahmad, H; Yazici, Yusuf; Liu, X; Bergman, MJ
ISI:000411824106468
ISSN: 2326-5205
CID: 2767512

Comparative Effectiveness of Secukinumab and Golimumab in Ankylosing Spondylitis: Assessed By Matching-Adjusted Indirect Comparison Using Pivotal Phase 3 Clinical Trial Data [Meeting Abstract]

Maksymowych, Walter P; Choy, Ernest; Yazici, Yusuf; Walsh, Jessica A; Thom, Howard; Kalyvas, Chrysostomos; Fox, Todd; Gandhi, Kunal; Jugl, Steffen
ISI:000411824103070
ISSN: 2326-5205
CID: 2767362

Analysis of Real-World Treatment Patterns in a Matched Sample of Rheumatology Patients with Continuous Infliximab Therapy or Switched to Biosimilar Infliximab [Meeting Abstract]

Ellis, Lorie A; Simsek, Ismail; Xie, Lin; Ogbomo, Adesuwa; Parenti, Dennis; Goyal, Kavitha; Yazici, Yusuf
ISI:000411824100454
ISSN: 2326-5205
CID: 2766912