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The role of patients' overall expectations of health on outcomes following proximal humerus fracture repair

Belayneh, Rebekah; Lott, Ariana; Haglin, Jack; Zuckerman, Joseph; Egol, Kenneth
INTRODUCTION/BACKGROUND:The purpose of this study is to evaluate the relationship between patients' own health expectations and treatment outcomes following surgical repair of proximal humerus fractures. HYPOTHESIS/OBJECTIVE:Patients' health expectations will correlate with treatment outcomes following surgical repair of proximal humerus fractures. MATERIAL AND METHODS/METHODS:Over a 14-year period, 247 patients with a displaced proximal humerus fracture who underwent ORIF with locking compression plates were prospectively followed at one academic institution. Minimum follow-up period was 12 months. Patient-reported functional outcome data for the latest follow up visit (12 months and greater) was obtained from Disabilities of Arm, Shoulder, and Hand (DASH) questionnaires. Survey responses regarding health expectations were recorded at 3-month follow-up and converted to dichotomous variables. Two groups were identified: the high expectations and the low expectations groups. Statistical analysis comparing the two groups and their functional and clinical outcomes was performed using the independent t-test, using p<0.05 for significance. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated to further statistically characterize the relationship between health expectations at 3 months and long-term outcomes. RESULTS:One hundred and eighty-five (75.0%) patients available for analysis with a mean follow-up length of 24.8 months. The cohort included 124 (67%) females and 61 (33%) males and the average age at time of injury was 59.5 years. Eighty-six (46.5%) patients had low expectations for their overall health and 99 (53.5%) patients had high expectations for their health. No significant differences were seen between groups in regards to age, gender, follow-up length, Charlson Comorbidity Index (CCI), smoking and tobacco use, fracture pattern (OTA and Neer classifications), early complications (p>0.05), fracture healing, and avascular necrosis. The mean DASH score at the latest follow up for patients with low expectations was 31.42±22.8 whereas the mean for those with high expectations was 16.76±20.2 (p<0.0005). The mean forward flexion of the shoulder for patients with low expectations was 137.8±31.5 degrees as compared to 148.5±26.3 degrees (p<0.05). The positive predictive value of good expectations correlating with good outcomes was 71.7%. DISCUSSION/CONCLUSIONS:Patients with high expectations for their health early following injury had better outcomes in the long term. These high expectations also appeared to have an optimal influence on range of shoulder motion. This data suggests attitudinal and psychological factors that affect patient health expectations early on in the course of treatment may also influence patients' functional and clinical outcomes. LEVEL OF EVIDENCE/METHODS:II; Retrospective Study.
PMID: 34389496
ISSN: 1877-0568
CID: 5010912

Minimal clinically important difference, substantial clinical benefit, and patient acceptable symptom state of PROMIS upper extremity after total shoulder arthroplasty

Gordon, Dan; Pines, Yaniv; Ben-Ari, Erel; As, Rokito; Kwon, Young W; Zuckerman, Joseph D; Virk, Mandeep S
Background/UNASSIGNED:The Patient-Reported Outcomes Measurement Information System minimal clinically important difference (PROMIS MCID), substantial clinical benefit (SCB), and patient acceptable symptom state (PASS) of patient-reported outcome measures provide clinical significance to patient-reported outcome measures scores. The goal of this study is to measure the MCID, SCB, and PASS of PROMIS Upper Extremity v2.0 (PROMIS UE) in patients undergoing total shoulder arthroplasty (TSA). Methods/UNASSIGNED:All patients who underwent TSA since October 2017 were identified from our institutional database. Patients who had completed the PROMIS UE outcome measure before surgery were asked to complete a PROMIS UE and anchor survey that contained two transition questions to assess patient satisfaction and change in symptoms since treatment. The anchor-based MCID, SCB, and PASS were calculated as the change in PROMIS UE score that represented the optimal cutoff for a receiver operating characteristic curve. The distribution-based MCID was calculated as a range between the average standard error of measurement multiplied by 2 different constants: 1 and 2.77. Results/UNASSIGNED:This study enrolled 165 patients. The anchor-based MCID for PROMIS UE was calculated to be 8.05 with an AUC of 0.814. The anchor-based SCB was calculated to be 10.0 with an AUC of 0.727. The distribution-based MCID was calculated to be between 3.12 and 8.65. The PASS was calculated to be 37.2 with an AUC of 0.90. Conclusions/UNASSIGNED:The establishment of MCID, SCB, and PASS for PROMIS UE scores after shoulder arthroplasty provides meaningful and objective clinical interpretation of the improvements in outcome scores after TSA.
PMCID:8411069
PMID: 34505102
ISSN: 2666-6383
CID: 5006552

Clinical outcomes of augmented rTSA glenoid baseplates

Gulotta, Lawrence V.; Grey, Sean G.; Flurin, Pierre Henri; Wright, Thomas W.; Zuckerman, Joseph D.; Roche, Christopher P.
Background: Glenoid wear is a common challenge in patients undergoing reverse total shoulder arthroplasty (rTSA). Augmented baseplates have recently been designed to address this. The purpose of this study is to determine the clinical outcomes, complications, and revision rates of patients undergoing rTSA with an augmented baseplate compared to those that received a standard, non-augmented baseplate. Methods: Preoperative and postoperative data were analyzed for 414 patients with glenoid bone loss who underwent primary rTSA with either an 8° posterior augmented glenoid baseplate, a 10° superior augmented baseplate (SAB), or an 8° posterior/10° superior augmented baseplate (P/SAB). These patients were compared to 1547 primary rTSA patients who received a standard baseplate. Clinical outcomes were scored using the Simple Shoulder Test (SST), UCLA, ASES, Constant and SPADI clinical outcome scoring metrics. Range of motion for active abduction, forward flexion, internal rotation and external rotation were used to quantify function. Complication and revision rates were also documented, and postoperative radiographs were analyzed for scapular notching. A two-tailed, unpaired t-test was used to identify differences between continuous parameters and a Chi Square test was used for categorical parameters, with P < .05 denoting a significant difference. Results: At an average follow-up of 47.1 ± 23.1 months, the augmented baseplates performed as well, or better, than standard baseplates, with a similar complication rate, revision rate, aseptic glenoid loosening rate, and scapular notching rate. Discussion: Augmented baseplates are a safe and effective option for patients with glenoid bone loss in the setting of rTSA at mid-term follow-up. For each baseplate type, the outcomes were similar, and the complication/revision and scapular notching rates were low and comparable to that of the standard baseplate cohort. Level of evidence: Level III
SCOPUS:85111016643
ISSN: 1045-4527
CID: 5000352

Excellent mid-term outcomes with a hemispheric titanium porous-coated acetabular component for total hip arthroplasty: 7-10 year follow-up

Yeroushalmi, David; Singh, Vivek; Maher, Nolan; Gabor, Jonathan A; Zuckerman, Joseph D; Schwarzkopf, Ran
INTRODUCTION/UNASSIGNED:Third-generation hemispheric, titanium porous-coated (HTPC) acetabular cups have been shown to achieve good biologic fixation through enhanced porous ingrowth surfaces. They also allow for a wide range of bearing options, including polyethylene, dual-mobility, and ceramic liners. The purpose of the study is to review the mid-term clinical outcomes an HTPC acetabular cup with a minimum of 7-year follow-up. METHODS/UNASSIGNED:A retrospective, observational study was conducted on all consecutive patients who underwent total hip arthroplasty (THA) with an HTCP acetabular cup at an urban, tertiary referral centre. Descriptive statistics were used describe baseline patient characteristics. Outcomes collected included postoperative complications, survival free of reoperations, and presence of osteolysis at latest imaging follow-up. Implant survival was analysed using the Kaplan-Meier method. RESULTS/UNASSIGNED:118 cases (114 primary, 4 revision) underwent THA with the HTCP acetabular cup at an average follow-up of 8.16 ± 0.85 years (range 7.02-10.28 years). Mean patient age at the time of surgery was 61.29 ± 12.04 years. All cases utilised a high molecular weight polyethylene (HMWPE) liner. None of the acetabular cups showed loosening or migration at the latest follow-up. There were 2 revisions in our study, 1 for abductor mechanism disruption and 1 due to surgical site infection where the acetabular cup was revised. Kaplan-Meier Survivorship analysis for all-cause revision at 7 and 10-year follow-up showed a survival rate of 99.1% (95% confidence interval, 94.1-99.9%). Survivorship analysis for aseptic acetabular revision at 10-year follow-up showed a survival rate of 100%. CONCLUSIONS/UNASSIGNED:At long-term follow-up, no radiologic and minimal clinical complications were identified in this series. The HTPC acetabular cup system, used in conjunction with a HMWPE liner, demonstrates excellent outcomes and survivorship when compared to earlier mid-term studies published in the literature.
PMID: 34412531
ISSN: 1724-6067
CID: 4988932

Reverse shoulder arthroplasty for massive irreparable rotator cuff tears: a reliable treatment method

Boin, Michael A.; Ben-Ari, Erel; Roche, Christopher P.; Zuckerman, Joseph D.
Background: Massive irreparable rotator cuff tears (MIRCT) are challenging problems for both patients and surgeons. Reverse total shoulder arthroplasty (RTSA) is a treatment option for patients with MIRCTs. However, previous reports have shown inconsistent results, varying patient satisfaction, and higher complication rates. Methods: This is a retrospective multi-institutional study (22 institutions, 24 surgeons) of 203 patients (average age, 71 years) who underwent RTSA for MIRCT without glenohumeral arthritis with a mean follow-up of 50 months. Patients were divided into 4 groups based on preoperative shoulder active forward elevation (aFE) (<60°, <90°, ≥90°, >120°). Clinical outcomes were assessed using multiple patient-reported outcome measures (PROs), postoperative range of motion (ROM), patient satisfaction, and complication rate. Radiographic outcomes assessment included evaluation of postoperative scapular notching and humeral radiolucent lines. Results: Patients in each group had significant (P≤ 0.02) improvements in PROs and ROM postoperatively. Patient satisfaction was highest in the group with >120° preoperative aFE (44/44, 100%). Scapular notching and humeral radiolucency were noted in 6% and 7% of patients, respectively. There were only 3 complications that required 2 revision surgeries. Overall, the complication rate (1.6%) and reoperation rate (1.1%) were considerably lower than previously reported. Conclusion: RTSA is a reliable treatment for MIRCTs without glenohumeral arthritis that results in significant improvements in PROs and shoulder ROM. Compared to previous studies, we report a substantially higher satisfaction rates in all patients, especially in those with better preoperative ROM (aFE >120°), and a lower overall complication rate. Level of evidence: Level IV; Therapeutic Study
SCOPUS:85110459677
ISSN: 1045-4527
CID: 4964242

Shoulder Hemiarthroplasty for Proximal Humerus Fracture

Schultz, Blake J; Lowe, Dylan T; Egol, Kenneth A; Zuckerman, Joseph D
SUMMARY:There are a variety of treatment options available for proximal humerus fractures, including nonoperative management, open reduction internal fixation with screws, locking plates, intramedullary nailing, or suture fixation, and arthroplasty, including hemiarthroplasty and total shoulder replacements. Fracture characteristics, including the number of fracture parts and involvement of the humeral head and glenoid and the patient's functional status and postoperative goals help dictate the optimal choice. Although the indications for hemiarthroplasty as treatment for severe proximal humerus fractures have narrowed, the authors believe that there is a still a place for this technique in practice.
PMID: 34227587
ISSN: 1531-2291
CID: 4965152

Comparison of radiographs and computed tomography (CT) imaging for preoperative evaluation and planning for shoulder arthroplasty

Liuzza, Lindsey G.; Abdelshahed, Mina M.; Oh, Cheongeun; Roach, Ryan; Looze, Christopher; Capeci, Craig; Kwon, Young W.; Zuckerman, Joseph D.; Virk, Mandeep S.
Background: The purpose of this study was to determine if addition of CT to axillary radiographs (AXR) alters preoperative decision making for shoulder arthroplasty. Methods: Preoperative deidentified images (XR alone and XR with CT) of 50 patients with glenohumeral arthritis were reviewed independently by 3 reviewers in a blinded fashion. Each reviewer graded images for glenoid wear pattern as simple (Walch A1 or B1) or advanced [A2, B2, C]), adequacy of AXR and need for advanced imaging. The reviewers determined a preoperative plan for all patients based on XR alone vs. XR and CT including the arthroplasty type (anatomic or reverse total shoulder) and their plan for treating glenoid wear (eccentric or standard reaming vs. bone graft or augment). Kappa values (κ) were calculated to determine inter-rater agreement and consistency among multiple reviewers. Fisher's exact test was used to assess any difference in preoperative plan once the shoulders were separated into simple and advanced glenoid wear patterns. Results: The 3 reviewers agreed that quality of AXRs was significantly inadequate (P <.001) for assessing glenoid wear in advanced glenoid wear patterns compared to simple wear patterns. Following evaluation on AXRs alone, the need for CT imaging was significantly higher in advanced glenoid wear patterns compare to simple ones (81% vs. 31%; P <.001). The addition of CT images did not result in a significant change to the preoperative plan in simple glenoid wear patterns but in advanced glenoid wear, addition of CT can change the preoperative plan with respect to arthroplasty type and/or strategy for addressing glenoid wear. Conclusion: Axillary radiographs are often inadequate for preoperative planning in shoulder arthritis with advanced glenoid wear patterns (Walch A2, B2, C types). Addition of CT imaging to radiographs in shoulder arthritis with advanced glenoid wear can affect the preoperative decision with respect to type of shoulder arthroplasty and/or plan for addressing glenoid wear (reaming, bone graft or augmented glenoids). Level of evidence: Level IV
SCOPUS:85107128369
ISSN: 1045-4527
CID: 4921782

The Impact of Global Spinal Alignment on Standing Spinopelvic Alignment Change After Total Hip Arthroplasty

Jain, Deeptee; Vigdorchik, Jonathan M; Abotsi, Edem; Montes, Dennis Vasquez; Delsole, Edward M; Lord, Elizabeth; Zuckerman, Joseph D; Protopsaltis, Themistocles; Passias, Peter G; Buckland, Aaron J
STUDY DESIGN/UNASSIGNED:Retrospective cohort study. OBJECTIVES/UNASSIGNED:The interactions between hip osteoarthritis (OA) and spinal malalignment are poorly understood. The purpose of this study was to assess the influence of total hip arthroplasty (THA) on standing spinopelvic alignment. METHODS/UNASSIGNED:In this retrospective cohort study, patients undergoing THA for OA with pre-and postoperative full-body radiographs were included. Standing spinopelvic parameters were measured. Contralateral hip was graded on the Kellgren-Lawrence scale. Pre-and postoperative alignment parameters were compared by paired t-test. The severity of preoperative thoracolumbar deformity was measured using TPA. Linear regression was performed to assess the impact of preoperative TPA and changes in spinal alignment. Patients were separated into low and high TPA (<20 or >/=20 deg) and change in parameters were compared between groups by t-test. Similarly, the influence of K-L grade, age, and PI were also tested. RESULTS/UNASSIGNED:= .004). Preoperative TPA was significantly associated with the change in PI-LL, SVA, and TPA. High TPA patients significantly decreased SVA more than low TPA patients. There was no significant impact of contralateral hip OA, PI, or age on change in alignment parameters. CONCLUSION/UNASSIGNED:Spinopelvic alignment changes after THA, evident by a reduction in SVA. Preoperative spinal sagittal deformity impacts this change. Level of evidence: III.
PMID: 34142571
ISSN: 2192-5682
CID: 4917752

The future of healthcare service in orthopedic practice: Telemedicine or in-person visits?

Ben-Ari, Erel; Kirshenbaum, Joshua; Patel, Ruby G; Kwon, Young W; Rokito, Andrew S; Zuckerman, Joseph D; Virk, Mandeep S
BACKGROUND:The objective of this study is to assess patient satisfaction and preference for telemedicine- versus in-person visits for outpatient shoulder and elbow musculoskeletal consultation during the COVID-19 pandemic and in the future. METHODS:Patients who had telemedicine visits for shoulder and elbow musculoskeletal complaints at a single institution from March through June, 2020, were invited to respond to a post-visit survey. The survey included a standardized questionnaire that focused on the patient's satisfaction with the telemedicine visit(s) during the pandemic and preference for using the telemedicine platform in the future following the pandemic. Additional details regarding their virtual visits (severity of their medical condition, previous virtual- or ER visits) were also obtained. Data regarding patient demographics and visit details (primary diagnosis, type of visit, length of visit, treating physician) were extracted from electronic medical records. RESULTS:In total, 153 patients participated in the study. Overall, high satisfaction scores regarding the telemedicine visit were noted: 91% of patients reported that their concerns were adequately addressed, 89% would recommend telemedicine to a friend and 94% stated that they would use this platform again in the presence of a situation like the COVID-19 pandemic. However, the majority of patients (76%) reported a preference for in-person visits for the same musculoskeletal complaint if it were not for COVID-19. A telemedicine visit duration of more than 10 minutes and a first-time telemedicine visit correlated with higher satisfaction rates (P=0.037 and P=0.001, respectively). CONCLUSIONS:COVID-19 has provided a boost to the use of our telemedicine platform, with a high satisfaction rate among patients with shoulder and elbow musculoskeletal complaints, largely due to safety reasons and limited access to in-person doctor visits. However, a considerable number of patients would have preferred in-person visits for similar health complaints if there were no pandemic. Further research on optimizing the selection of patients for telemedicine visits and addressing their expectations and concerns regarding their visits will improve patients' preference for future telemedicine visits.
PMID: 34089879
ISSN: 1532-6500
CID: 4899382

Investigation of Foot Sensor Insoles for Measuring Functional Outcome After Total Knee Replacement

Chu, Lauren M; Walker, Peter S; Iorio, Richard; Zuckerman, Joseph D; Slover, James D; Lajam, Claudette M; Schwarzkopf, Ran
BACKGROUND:To measure functional outcome, patient reported outcome measures (PROMs) are most often used but biomechanical tests can provide valuable supplementary data. The objective of this study was to investigate instrumented insoles for measuring ground-to-foot forces during basic activities. METHODS:Three groups were evaluated: normal controls, preoperative, and postoperative total knees. The Knee Society Scoring System (KSS) Short Form was used, and with foot pressure sensor insoles, a timed-up-and-go (TUG) test and a sit-to-stand (STS) test was used. RESULTS:Comparing preoperative to postoperative and control groups, there were significant differences in most parameters. There were no significant differences between controls and postoperative knees. Of the 33 correlation coefficients between three PROM parameters and six biomechanical parameters for the three groups, only five coefficients were greater than 0.5. CONCLUSIONS:The biomechanical data was substantially independent of the PROM data and provided additional functional evaluation. The most useful parameters were the left-right force ratios during sit-to stand (STS) and the timed-up-and-go (TUG) time.
PMID: 34081888
ISSN: 2328-5273
CID: 4891892