Searched for: in-biosketch:true
person:goldfl03
Racially and ethnically selective oligoanalgesia: is this racism? [Comment]
Goldfrank LR; Knopp RK
PMID: 10613944
ISSN: 0196-0644
CID: 44361
The Medical Toxicology Fellowship
Goldfrank LR
ORIGINAL:0004782
ISSN: 0731-3810
CID: 44436
The next century : mission impossible with universal health care [Editorial]
Goldfrank LR
ORIGINAL:0004760
ISSN: 1054-0725
CID: 44414
Poisoning
Chapter by: Nelson LS; Goldfrank LR
in: Melmon and Morrelli's clinical pharmacology by Carruthers SG [Eds]
New York : McGraw-Hill, 2000
pp. 1091-1113
ISBN: 0071054065
CID: 3305
Management of the multiply injured or intoxicated patient
Chapter by: Delaney KA; Goldfrank LR
in: Head injury by Cooper PR [Eds]
New York : McGraw-Hill, 2000
pp. 41-62
ISBN: 0838536875
CID: 3297
The Homeless patient
Chapter by: Rao RB; Goldfrank LR
in: Emergency medicine : a comprehensive study guide by Tintinalli JE; Kelen GD; Stapczynski JS [Eds]
New York : McGraw-Hill, 2000
pp. 2014-2015
ISBN: 0070653518
CID: 3321
Poisoning
Chapter by: Nelson LS; Goldfrank LR
in: Melmon and Morrelli's clinical pharmacology: basic principles in therapeutics by Melmon KL; Morrelli HF; Carruthers SG [Eds]
New York : McGraw-Hill, 2000
pp. ?-?
ISBN: 0071054065
CID: 4129
A prospective evaluation of the electrocardiographic manifestations of hypothermia
Vassallo SU; Delaney KA; Hoffman RS; Slater W; Goldfrank LR
OBJECTIVE: To determine the effects of body temperature, ethanol use, electrolyte status, and acid-base status on the electrocardiograms (ECGs) of hypothermic patients. METHODS: Prospective, two-year, observational study of patients presenting to an urban ED with temperature < or =95 degrees F (< or =35 degrees C). All patients had at least one ECG obtained. Electrocardiograms were interpreted by a cardiologist blinded to the patient's temperature. J-point elevations known as Osborn waves were defined as present if they were at least 1 mm in height in two consecutive complexes. RESULTS: 100 ECGs were obtained in 43 patients. Presenting temperatures ranged between 74 degrees F and 95 degrees F (23.3 degrees C-35 degrees C). Initial rhythms included normal sinus (n = 34), atrial fibrillation (n = 8), and junctional (n = 1). Osborn waves were present in 37 of 43 initial ECGs. Of the six initial ECGs that did not have Osborn waves present, all were obtained in patients whose temperatures were > or =90 degrees F > or =32.2 degrees C). For the entire group, the Osborn wave was significantly larger as temperature decreased (p = 0.0001, r = -0.441). The correlation between temperature and size of the Osborn wave was strongest in six patients with four or more ECGs (range r = -0.644 to r = -0.956, p = 0.001). No correlation could be demonstrated between the height of the Osborn waves and the serum electrolytes, including sodium, chloride, potassium, bicarbonate, BUN, creatinine, glucose, anion gap, and blood ethanol levels. CONCLUSIONS: The presence and size of the Osborn waves in hypothermic patients appear to be a function of temperature. The magnitude of the Osborn waves is inversely correlated with the temperature
PMID: 10569384
ISSN: 1069-6563
CID: 56484
David R. Boyd lecture in trauma care and emergency medical systems: "The surgical complications of toxins." [Lecture]
Goldfrank LR
Toxins have had major roles in our societies for thousands of years. Interactions between surgeons, both generalists and subspecialists, and those caring for poisoned patients have been extensive throughout history. The advancement of the science of toxicology, the development of regional poison control centers, the development of emergency medicine, and the development of the subspecialty of medical toxicology have led to more appropriate and creative interactions between medical toxicologists, emergency physicians, and surgeons. This article will review the diverse interfaces between the medical toxicologist and the surgeon
PMID: 10595897
ISSN: 0736-4679
CID: 39447
Occupational exposures to blood among emergency medicine residents
Lee CH; Carter WA; Chiang WK; Williams CM; Asimos AW; Goldfrank LR
OBJECTIVES: To investigate the epidemiologic characteristics of potentially infectious occupational exposures to blood among emergency medicine (EM) residents. METHODS: A SAEM-sponsored multiple-choice survey was administered anonymously to all EM residents participating in the 1998 American Board of Emergency Medicine in-service examination. Survey questions included resident demographics, use of universal precautions, frequency and types of exposures to blood, and exposure reporting. Residents who experienced at least one exposure were then asked to complete an additional set of questions referring only to their latest exposure. Mean values were calculated for each variable and differences between groups were compared by chi-square analysis. RESULTS: Three thousand one hundred sixty-two surveys were distributed to the resident participants, and 2,985 surveys (94.4%) were returned. Of the participants, 56.1% reported at least one exposure to blood during their EM training. The frequency of this self-reported exposure increased with advancing EM level of training (43% EM-1, 58% EM-2, 64% EM-3, 76% EM-4, p<0.001). Of these residents, 36.6% always followed universal precautions, 54% frequently, and 9.4% sometimes, rarely, or never. Those individuals who 'always' followed universal precautions reported significantly fewer exposures than those who did not (p<0.005). The latest exposures were most commonly caused by a solid needle or sharp object (39.4%), by a hollow-bore needle (30.6%), or by eye splashes (17.2%). Of these exposures, 71.7% occurred in the ED setting, and only 46.7% of these exposures were reported to health care providers. CONCLUSION: Emergency medicine residents are frequently exposed to blood, most commonly due to puncture injuries by sharp objects. The rate of exposure reporting is low, which may compromise appropriate postexposure counseling and prophylaxis
PMID: 10530663
ISSN: 1069-6563
CID: 6222