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High Return to Sport in Patients Over 45 Years of Age Undergoing Osteochondral Allograft Transplantation for Isolated Chondral Defects in the Knee
Markus, Danielle H; Hurley, Eoghan T; Haskel, Jonathan D; Manjunath, Amit K; Campbell, Kirk A; Gonzalez-Lomas, Guillem; Strauss, Eric J; Alaia, Michael J
OBJECTIVE/UNASSIGNED:The purpose of this study was to evaluate the efficacy of osteochondral allograft (OCA) in patients older than 45 years of age, particularly with respect to return to sport. DESIGN/UNASSIGNED:A retrospective review was performed to evaluate patients greater than 45 who underwent an OCA for a symptomatic osteochondral defect of the knee between June 2011 and January 2019. RESULTS/UNASSIGNED:< 0.01). Furthermore, the mean Visual Analogue Scale while playing sport was 3.4 ± 3.2, and the mean Knee Injury and Osteoarthritis Outcome Score was 77.5 ± 12.7 at final follow-up. Overall, 11 patients (78.6%) were able to return to their desired sport. No clinical failures were identified during the follow-up period. CONCLUSION/UNASSIGNED:In our series of patients 45 years and older who were treated with OCA for focal osteochondral injuries of the knee, we found a significant improvement in clinical outcome scores at a midterm follow-up of 37 months with no revision OCA procedures or conversion to any form of knee arthroplasty. In addition, a high percentage of patients were able to return to their preferred level of athletic activity.
PMID: 34521255
ISSN: 1947-6043
CID: 5012312
Staged Reconstruction of a Moore Type 4 Fracture Dislocation, Parts 1 and 2
Schultz, Blake J; Lowe, Dylan T; Pean, Christian A; Alaia, Michael J; Egol, Kenneth A
SUMMARY:High-energy tibial plateau fractures are associated with knee fracture dislocations and concomitant ligamentous injury. Both bony and ligamentous injuries can require surgical fixation, often requiring a multidisciplinary team and staged treatment. This article and accompanying video describe the workup and treatment of a Moore type 4 tibial plateau rim compression fracture with posterolateral corner and anterior cruciate ligament rupture that underwent open reduction internal fixation of the tibial plateau with posterolateral corner reconstruction and then staged anterior cruciate ligament reconstruction with quad tendon autograft.
PMID: 34227606
ISSN: 1531-2291
CID: 5003752
Cartilage Restoration of Bipolar Lesions Within the Patellofemoral Joint Delays Need for Arthroplasty: A Systematic Review of Rates of Failure
Gowd, Anirudh K; Weimer, Alexander E; Rider, Danielle E; Beck, Edward C; Agarwalla, Avinesh; O'Brien, Lisa K; Alaia, Michael J; Ferguson, Cristin M; Waterman, Brian R
Purpose/UNASSIGNED:The purpose of the present review is to systematically review the available literature for failure rates and complications of cartilage restoration of bipolar chondral defects in the patellofemoral (PF) joint to assess the ability to treat these lesions without arthroplasty. Methods/UNASSIGNED:PubMed and MEDLINE databases were queried between 2000 to 2020 using the keywords "osteochondral" and "knee" and "microfracture," "autologous chondrocyte implantation (ACI)," or "transplantation." Patient selection included patients with bipolar chondral lesions of the patellofemoral joint that were treated with cartilage restoration procedures. Treatment of PF joints were reviewed for surgical indications/technique, rates of failure, defect characteristics, and time to failure. For the purposes of this study, failure was defined by each individual author on their respective studies. Results/UNASSIGNED:Â = 79.0%). Conclusion/UNASSIGNED:From the available data, established cartilage restoration procedures may provide favorable patient-reported function, avoidance of secondary surgery, and joint preservation in at least 80% of patients at short- to mid-term follow-up. Level of Evidence/UNASSIGNED:Level IV, systematic review of Level IV studies.
PMCID:8365210
PMID: 34430900
ISSN: 2666-061x
CID: 4989092
Cartilage Restoration for Tibiofemoral Bipolar Lesions Results in Promising Failure Rates: A Systematic Review
Gowd, Anirudh K; Weimer, Alexander E; Rider, Danielle E; Beck, Edward C; Agarwalla, Avinesh; O'Brien, Lisa K; Alaia, Michael J; Ferguson, Cristin M; Waterman, Brian R
Purpose/UNASSIGNED:The purpose of the present study is to systematically review the available literature for management of bipolar lesions within the tibiofemoral joint and determine whether tibiofemoral cartilage restoration is an effective treatment modality. Methods/UNASSIGNED:PubMed and MEDLINE databases were queried between 2000 and 2020 using the following keywords: "osteochondral" and "knee" and "microfracture," "autologous chondrocyte implantation (ACI)," or "transplantation." Articles were reviewed for the presence of a bipolar or "kissing" tibiofemoral lesion and reported lesion size, concomitant procedures, failure rates, and time to failure. Results/UNASSIGNED:Â = 79.1%). Conclusions/UNASSIGNED:Cartilage restoration, through both ACI and OCA, had failure rates between 0% and 44% in patients with bipolar lesions of the tibiofemoral compartment. Although a higher level of evidence is required to prove efficacy, the current study demonstrates midterm survivorship rates between 55% and 100%, which may delay the need for secondary arthroplasty. Level of Evidence/UNASSIGNED:Level IV, systematic review of Level IV studies.
PMCID:8365214
PMID: 34430903
ISSN: 2666-061x
CID: 4989102
Tibial Sagittal Slope in Anterior Cruciate Ligament Injury and Treatment
Alaia, Michael J; Kaplan, Daniel J; Mannino, Brian J; Strauss, Eric J
Although anterior cruciate ligament reconstruction (ACLR) is a generally successful procedure, failure is still relatively common. An increased posterior tibial slope (PTS) has been shown to increase the anterior position of the tibia relative to the femur at rest and under load in biomechanical studies. Increased PTS has also been shown to increase forces on the native and reconstructed ACL. Clinical studies have demonstrated elevated PTS in patients with failed ACLR and multiple failed ACLR, compared with control subjects. Anterior closing-wedge osteotomies have been shown to decrease PTS and may be indicated in patients who have failed ACLR with a PTS of ≥12°. Available clinical data suggest that the procedure is safe and effective, although evidence is limited to case series. This article presents the relevant biomechanics, clinical observational data on the effects of increased PTS, and an algorithm for evaluating and treating patients with a steep PTS.
PMID: 34288895
ISSN: 1940-5480
CID: 4950492
Author Reply to "Regarding 'Tranexamic Acid Has No Effect on Postoperative Hemarthrosis or Pain Control After Anterior Cruciate Ligament Reconstruction Using Bone-Patellar Tendon-Bone Autograft: A Double-Blind, Randomized, Controlled Trial'" [Letter]
Alaia, Michael J; Fried, Jordan W; Bloom, David A; Hurley, Eoghan T; Popovic, Jovan; Baron, Samuel L; Campbell, Kirk A; Strauss, Eric J; Jazrawi, Laith M
PMID: 34225992
ISSN: 1526-3231
CID: 4932982
Bone-Patellar Tendon-Bone Autograft Thickness Is a Risk Factor for Graft Failure. A Case-Control Analysis
Roach, Ryan; Anil, Utkarsh; Bloom, David A; Pham, Hien; Jazrawi, Laith; Alaia, Michael J; Gonzalez-Lomas, Guillem
BACKGROUND:Graft failure following anterior cruciate ligament reconstruction (ACLR) is a devastating complication. Risk factors such as patient characteristics and tunnel positions are well described. The relationship between graft dimension and failure rates has been investigated mainly in soft tissue grafts. Less studied are the effects of patella tendon (PT) dimensions on the risk of graft failure following patella tendon autograft (PTA) reconstructions. PURPOSE/OBJECTIVE:The purpose of the current study was to investigate if patellar tendon thickness measured on preoperative magnetic resonance imaging (MRI) predicts failure after ACLR using PTA. METHODS:This was an institutional review board approved, single-center, retrospective case-control study comparing patients' preoperative patellar tendon thickness between July 2005 and January 2017. Sixteen patients (mean age 21.2 ± 5.0 years) with PTA failure requiring revision surgery were identified and compared to 34 control patients who had undergone primary ACLR with PTA without failure with a minimum of 2-years follow-up. Patients with failure were matched at approximately 1:2 based on age, sex, height, weight, associated meniscus injury, and associated meniscal surgery. Patellar tendon dimensions were measured at the inferior pole of the patella (IPP), tibial tubercle insertion (TT), and longitudinal midpoint (MP) on preoperative axial and sagittal cut MRIs. Interclass correlation coefficeint (ICC) and Bland-Altman analyses were evaluated to determine inter-observer reliability. The two cohorts were compared using independent samples t-tests and analysis of variance. RESULTS:All ACLR failures occurred after a non-contact, pivot type injury. There were no significant differences in age, sex, height, weight, meniscal injury, or meniscal surgery between the two groups. Mean time between primary ACLR and revision was 2.6 ± 2.6 years and mean follow-up time was 3.1 ± 1.0 years in the control group. Patellar tendon length and width were not significantly different between the two groups. The average thickness at both the inferior pole and longitudinal midpoint was significantly higher in the failure group compared to controls (IPP: 5.04 ± 1.1 mm versus 4.33 ± 0.7 mm, p = 0.01; MP: 4.60 ± 0.7 mm versus 4.22 ± 0.5 mm, p = 0.03). Additionally, ICC was high across all measurements, with all values > 0.978. Similarly, all values demonstrated bias of less than ± 0.05. CONCLUSION/CONCLUSIONS:Patella tendon autograft anterior cruciate ligament reconstruction failures had significantly thicker patellar tendons at the inferior pole and longitudinal midpoint of the patella tendon.
PMID: 34081882
ISSN: 2328-5273
CID: 4891852
No Difference in Outcomes Following Osteochondral Allograft with Fresh Precut Cores Compared to Hemi-Condylar Allografts
Markus, Danielle H; Blaeser, Anna M; Hurley, Eoghan T; Mannino, Brian J; Campbell, Kirk A; Jazrawi, Laith M; Alaia, Michael J; Strauss, Eric J; Alaia, Erin F
OBJECTIVE:The purpose of the current study is to evaluate the clinical and radiographic outcomes at early to midterm follow-up between fresh precut cores versus hemi-condylar osteochondral allograft (OCAs) in the treatment of symptomatic osteochondral lesions. DESIGN/METHODS:A retrospective review of patients who underwent an OCA was performed. Patient matching between those with OCA harvested from an allograft condyle/patella or a fresh precut allograft core was performed to generate 2 comparable groups. The cartilage at the graft site was assessed with use of a modified Magnetic Resonance Observation of Cartilage Repair Tissue (MOCART) scoring system and patient-reported outcomes were collected. RESULTS:= 0.93). CONCLUSIONS:This study found that there was no difference in patient-reported clinical outcomes or MOCART scores following OCA implantation using fresh precut OCA cores or size matched condylar grafts at early to midterm follow-up.
PMID: 34078119
ISSN: 1947-6043
CID: 4891652
Reduced opioid prescribing following arthroscopic meniscectomy does not negatively impact patient satisfaction
Bloom, David A; Manjunath, Amit K; Kaplan, Daniel J; Egol, Alexander J; Campbell, Kirk A; Strauss, Eric J; Alaia, Michael J
BACKGROUND:Prior research has demonstrated that physician desire to optimize patient satisfaction is a cause of over-prescription of opioid medications in the healthcare setting. The purpose of this study was to investigate what effect, if any, decreased opioid prescribing following arthroscopic meniscectomy had on Press-Ganey (PG) satisfaction survey scores. METHODS:A retrospective review of prospectively-collected data was conducted on patients who underwent arthroscopic meniscectomy between October2014-October2019. Inclusion criteria consisted of complete PG information, no history of trauma, connective tissue disease, or prior knee surgery. Groups were separated based on date of surgery relative to implementation of an institutional opioid reduction policy which occurred on October 1, 2018. Prescriptions were converted to milligram-morphine-equivalents (MME) for direct comparison between opioids. Minimal-Detectable-Change (MDC) was calculated to evaluate clinical significance of any statistically significant findings. RESULTS:554 patients were included in this analysis (452pre-protocol, 102post-protocol). The groups did not differ statistically (p > 0.05) with respect to any patient demographics (age, BMI, sex, prior opioid use, opioid naivete) with the exception of smoking history; 54.4% in the pre-protocol group and 32.4%in the post-protocol group; p < 0.001. Mean discharge dose for the pre-protocol group was 229.3 ± 141MME, and 80.05 ± 82.7MME post-protocol; P < 0.0001. There were no statistically significant differences between pre-and-post-protocol satisfaction with pain control scores; P = 0.15. The differences between satisfaction with pain control did not meet clinical or statistical significance, based on a calculated MDC = 0.368. Among pre-protocol patients, 372(82.3%) gave a "top box" response to the question "degree-to-which-your-pain-was-controlled", compared to 91(89.2%) from the post-protocol group; P = 0.10. CONCLUSION/CONCLUSIONS:A reduction in opioids prescribed after arthroscopic meniscectomy was not associated with any difference in patient satisfaction with pain management, as measured by the Press-Ganey survey. LOE: 3.
PMID: 33640620
ISSN: 1873-5800
CID: 4875172
Editorial Commentary: The Benefits of Tranexamic Acid May Outweigh Risks in Arthroscopy and Sports Medicine [Comment]
Alaia, Michael J; Gipsman, Aaron M
Tranexamic acid (TXA) is an antifibrinolytic that lowers the risk of hemarthrosis-related surgical complications and has been extensively studied in orthopaedic trauma surgery, primary and revision total joint replacement, open shoulder reconstruction, and spine surgery. Its use, however, has been minimally studied in orthopaedic sport medicine, and, in particular, arthroscopic surgery. Despite being an inexpensive medication with a minimal side effect profile, there has been a paucity of Level I and II studies to support or refute its use in some of the most common procedures performed in orthopaedic surgery. TXA may be of small benefit in routine partial meniscectomy or routine, outpatient, anterior cruciate ligament reconstruction. However, although there are potential risks and side effects of TXA, the risk is very low, the cost is very low, and even a small benefit may justify its use.
PMID: 33812531
ISSN: 1526-3231
CID: 4862402