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The role of patients"™ overall expectations of health on outcomes following proximal humerus fracture repair Importance de l'attente globale des patients en matière de santé sur les résultats après ostéosynthèse d'une fracture de l'humérus proximal

Belayneh, Rebekah; Lott, Ariana; Haglin, Jack; Zuckerman, Joseph; Egol, Kenneth
Introduction: The purpose of this study is to evaluate the relationship between patients"™ own health expectations and treatment outcomes following surgical repair of proximal humerus fractures. Hypothesis: Patients"™ health expectations will correlate with treatment outcomes following surgical repair of proximal humerus fractures. Material and methods: Over a 14-year period, 247 patients with a displaced proximal humerus fracture who underwent ORIF with locking compression plates were prospectively followed at one academic institution. Minimum follow-up period was 12 months. Patient-reported functional outcome data for the latest follow up visit (12 months and greater) was obtained from Disabilities of Arm, Shoulder, and Hand (DASH) questionnaires. Survey responses regarding health expectations were recorded at 3-month follow-up and converted to dichotomous variables. Two groups were identified: the high expectations and the low expectations groups. Statistical analysis comparing the two groups and their functional and clinical outcomes was performed using the independent t-test, using p < 0.05 for significance. Sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were calculated to further statistically characterize the relationship between health expectations at 3 months and long-term outcomes. Results: 185 (75.0%) patients available for analysis with a mean follow-up length of 24.8 months. The cohort included 124 (67%) females and 61 (33%) males and the average age at time of injury was 59.5 years. Eighty-six (46.5%) patients had low expectations for their overall health and 99 (53.5%) patients had high expectations for their health. No significant differences were seen between groups in regards to age, gender, follow-up length, Charlson Comorbidity Index (CCI), smoking and tobacco use, fracture pattern (OTA and Neer classifications), early complications (p > 0.05), fracture healing, and avascular necrosis. The mean DASH score at the latest follow up for patients with low expectations was 31.42 ± 22.8 whereas the mean for those with high expectations was 16.76 ± 20.2 (p < 0.0005). The mean forward flexion of the shoulder for patients with low expectations was 137.8 ± 31.5 degrees as compared to 148.5 ± 26.3 degrees (p < 0.05). The positive predictive value of good expectations correlating with good outcomes was 71,7%. Discussion: Patients with high expectations for their health early following injury had better outcomes in the long term. These high expectations also appeared to have an optimal influence on range of shoulder motion. This data suggests attitudinal and psychological factors that affect patient health expectations early on in the course of treatment may also influence patients"™ functional and clinical outcomes. Level of evidence: II; Retrospective Study.
SCOPUS:85118757020
ISSN: 1877-0517
CID: 5058852

Use of machine learning to assess the predictive value of 3 commonly used clinical measures to quantify outcomes after total shoulder arthroplasty

Kumar, Vikas; Roche, Christopher; Overman, Steven; Simovitch, Ryan; Flurin, Pierre Henri; Wright, Thomas; Zuckerman, Joseph; Routman, Howard; Teredesai, Ankur
Background: An important psychometric parameter of validity that is rarely assessed is predictive value. In this study we utilize machine learning to analyze the predictive value of 3 commonly used clinical measures to assess 2-year outcomes after total shoulder arthroplasty (TSA). Methods: XGBoost was used to analyze data from 2790 TSA patients and create predictive algorithms for the American Shoulder and Elbow Surgeons (ASES), Constant, and the University of California Los Angeles (UCLA) scores and also quantify the most meaningful predictive features utilized by these measures and for all questions comprising each measure to rank and compare their value to predict 2-year outcomes after TSA. Results: Our results demonstrate that the ASES, Constant, and UCLA measures rarely considered the most-predictive features relevant to 2-year TSA outcomes and that each outcome measure was composed of questions with different distributions of predictive value. Specifically, the questions composing the UCLA score were of greater predictive value than the Constant questions, and the questions composing the Constant score were of greater predictive value than the ASES questions. We also found the preoperative Shoulder Pain and Disability Index (SPADI) score to be of greater predictive value than the preoperative ASES, Constant, and UCLA scores. Finally, we identified the types of preoperative input questions that were most-predictive (subjective self-assessments of pain and objective measurements of active range of motion and strength) and also those that were least-predictive of 2-year TSA outcomes (subjective task-specific activities of daily living questions). Discussion: Machine learning can quantify the predictive value of the ASES, Constant, and UCLA scores after TSA. Future work should utilize this and related techniques to construct a more efficient and effective clinical outcome measure that incorporates subjective and objective input questions to better account for the preoperative factors that influence postoperative outcomes after TSA. Level of Evidence: Level III; Retrospective Comparative Study
SCOPUS:85101304942
ISSN: 1045-4527
CID: 4832492

Anatomic total shoulder arthroplasty and reverse total shoulder arthroplasty for dislocation arthropathy yield comparable functional outcomes with the matched cohort

Luthringer, Tyler A.; Colasanti, Christopher A.; Lin, Charles C.; Roche, Christopher; Magone, Kevin M.; Zuckerman, Joseph D.
Background: The aim of this study was to compare outcomes of anatomic total shoulder arthroplasty (aTSA) and reverse total shoulder arthroplasty (rTSA) after prior shoulder stabilization versus matched cohorts without previous stabilization surgery. Hypotheses were as follows: (1) patients undergoing aTSA or rTSA after stabilization procedures would have worse outcomes than matched cohorts and (2) patients undergoing TSA would have better outcomes after soft-tissue stabilization procedures (aTSAST or rTSAST) than after bony stabilization procedures (aTSAB or rTSAB). Methods: Retrospective cohort study was performed comparing (1) 36 patients who underwent aTSA and (2) 32 patients who underwent rTSA with prior shoulder stabilization with 3-to-1 matched cohorts (based on age, gender, and follow-up length) with no prior shoulder instability or surgery. Baseline demographics, perioperative data, adverse events (AEs), radiographic outcomes, functional outcome scores, range of motion (ROM), and patient satisfaction were analyzed. Subgroup analyses compared patients who underwent aTSAST or rTSAST with patients who underwent aTSAB or rTSAB. Results: The postoperative AE rate was 8.3% and 4.6% in the aTSA group and matched cohort, respectively (P =.404), with a trend toward a significantly higher incidence of aseptic glenoid loosening in the aTSA group (8.3% vs. 1.9%, P =.067). Functional outcomes, ROM, and patient satisfaction did not differ at follow-up >4 years. In the subgroup analysis, two AEs required reoperation among 25 patients who underwent aTSAST versus one among 11 patients who underwent aTSAB, all related to aseptic loosening. There was a trend toward greater functional outcomes and satisfaction among patients who underwent aTSAST. There was a trend toward a clinically significant difference in active abduction at final follow-up favoring aTSAST (128 vs. 108 degrees, P =.096). The postoperative AE rate was 6.3% and 4.2% among the rTSA group and matched cohort, respectively (P =.632). Functional outcomes, ROM, and patient satisfaction did not differ at 4-year follow-up. In the subgroup analysis, no AEs were reported among 18 patients who underwent rTSAST and 14 patients who underwent rTSAB. A trend toward greater functional outcomes and patient satisfaction favored patients who underwent rTSAB, who achieved greater improvements in ROM from baseline and greater ROM in all planes at the final follow-up. Conclusion: Both aTSA and rTSA are reliable options for the treatment of dislocation arthropathy in appropriately selected patients. aTSA and rTSA after prior shoulder stabilization procedures have nearly equal rates of AEs and yield similar clinical and functional outcomes as matched cohorts. There may be an increased risk of glenoid aseptic loosening in aTSA after prior shoulder stabilization. Functional outcomes tend to be greater for patients who underwent aTSAST than those for patients who underwent aTSAB. On the contrary, rTSA may optimize postoperative function when performed for dislocation arthropathy after bony rather than soft-tissue stabilization procedures. Level of evidence: Level III; Retrospective Cohort Design; Treatment Study
SCOPUS:85119211610
ISSN: 1045-4527
CID: 5059932

Clinical outcomes of augmented rTSA glenoid baseplates

Gulotta, Lawrence V.; Grey, Sean G.; Flurin, Pierre Henri; Wright, Thomas W.; Zuckerman, Joseph D.; Roche, Christopher P.
Background: Glenoid wear is a common challenge in patients undergoing reverse total shoulder arthroplasty (rTSA). Augmented baseplates have recently been designed to address this. The purpose of this study is to determine the clinical outcomes, complications, and revision rates of patients undergoing rTSA with an augmented baseplate compared to those that received a standard, non-augmented baseplate. Methods: Preoperative and postoperative data were analyzed for 414 patients with glenoid bone loss who underwent primary rTSA with either an 8° posterior augmented glenoid baseplate, a 10° superior augmented baseplate (SAB), or an 8° posterior/10° superior augmented baseplate (P/SAB). These patients were compared to 1547 primary rTSA patients who received a standard baseplate. Clinical outcomes were scored using the Simple Shoulder Test (SST), UCLA, ASES, Constant and SPADI clinical outcome scoring metrics. Range of motion for active abduction, forward flexion, internal rotation and external rotation were used to quantify function. Complication and revision rates were also documented, and postoperative radiographs were analyzed for scapular notching. A two-tailed, unpaired t-test was used to identify differences between continuous parameters and a Chi Square test was used for categorical parameters, with P < .05 denoting a significant difference. Results: At an average follow-up of 47.1 ± 23.1 months, the augmented baseplates performed as well, or better, than standard baseplates, with a similar complication rate, revision rate, aseptic glenoid loosening rate, and scapular notching rate. Discussion: Augmented baseplates are a safe and effective option for patients with glenoid bone loss in the setting of rTSA at mid-term follow-up. For each baseplate type, the outcomes were similar, and the complication/revision and scapular notching rates were low and comparable to that of the standard baseplate cohort. Level of evidence: Level III
SCOPUS:85111016643
ISSN: 1045-4527
CID: 5000352

Does reverse total shoulder arthroplasty for proximal humeral fracture portend poorer outcomes than for elective indications?

Crespo, Alexander M; Luthringer, Tyler A; Frost, Alexander; Khabie, Lily; Roche, Christopher; Zuckerman, Joseph D; Egol, Kenneth A
BACKGROUND:The number of reverse total shoulder arthroplasties (RTSAs) performed annually has increased, and the indications for RTSA have expanded beyond rotator cuff arthropathy to include treatment of complex proximal humeral fractures. No studies exist comparing clinical, functional, and radiographic outcomes in patients receiving RTSA for the treatment of acute fracture vs. those undergoing the procedure for degenerative conditions. This study was designed to fill the void in this knowledge gap. We hypothesized that patients undergoing RTSA for fracture treatment would experience worse clinical outcomes than those undergoing elective RTSA. METHODS:A prospectively collected database was queried for patients undergoing RTSA between 2007 and 2016. Patients were sorted based on the indication for RTSA: treatment of acute proximal humeral fracture vs. "elective" treatment of degenerative conditions of the shoulder. Baseline demographic characteristics, intraoperative and perioperative complications, and clinical, functional, and radiographic outcomes were collected. Only patients with ≥2 years' follow-up were included. Final outcomes were compared between the fracture and elective groups. RESULTS:In total, 1984 patients met the inclusion criteria, with 1876 in the elective group and 108 in the fracture group. Compared with the elective RTSA group, the group undergoing RTSA for fracture treatment was older, was female dominant, and was less likely to have undergone a previous operation on the ipsilateral shoulder. RTSA for fracture was associated with a longer hospital length of stay and greater intraoperative blood loss. The incidence of postoperative adverse events was 7.1% in the elective group vs. 4.6% in the fracture group. Functional outcomes did not differ beyond 1 year or at mean final follow-up > 40 months. CONCLUSION/CONCLUSIONS:Despite differences in patient demographic characteristics, the outcome and complication profiles are similar between patients undergoing RTSA for acute fracture and those indicated for the treatment of degenerative conditions of the shoulder.
PMID: 33317704
ISSN: 1532-6500
CID: 4716462

CORR Insights (R): Musculoskeletal Urgent Care Centers Restrict Access for Patients with Medicaid Insurance Based on Policy and Location [Editorial]

Zuckerman, Joseph D.
ISI:000709480900021
ISSN: 0009-921x
CID: 5074162

ANESTHESIA IN TOTAL SHOULDER ARTHROPLASTY A Systematic Review and Meta-Analysis [Review]

Boin, Michael A.; Mehta, Devan; Dankert, John; Umeh, Uchenna O.; Zuckerman, Joseph D.; Virk, Mandeep S.
ISI:000756914000007
ISSN: 2329-9185
CID: 5242902

Comparison of survivorship and performance of a platform shoulder system in anatomic and reverse total shoulder arthroplasty

Flurin, Pierre Henri; Tams, Carl; Simovitch, Ryan W; Knudsen, Christopher; Roche, Christopher; Wright, Thomas W; Zuckerman, Joseph; Schoch, Bradley S
Background/UNASSIGNED:Contemporary studies note sustained clinical benefit and decreasing complications after reverse total shoulder arthroplasty (RTSA), which warrant a comparison with the standard anatomic total shoulder arthroplasty (ATSA). The purpose of this study is to evaluate and compare differences in midterm survivorship between ATSA and RTSA patients treated with a single platform shoulder prosthesis. Secondary objectives include a comparison of the clinical outcomes and complication profile for each procedure. Methods/UNASSIGNED:A prospective analysis of all primary ATSA and RTSA performed by 3 surgeons between 2007 and 2012 was conducted. Selection of the ATSA or RTSA implant configuration was determined by the surgeons per their clinical understanding of each individual patient's glenoid morphology, rotator cuff, and patient expectations. All 778 procedures were performed using a single platform shoulder system. Results/UNASSIGNED:= .414). Conclusions/UNASSIGNED:On the basis of this cohort comparison, both ATSA and RTSA demonstrated similar survivorship at 8 years after surgery with multiple surgeons practicing in different countries. Our results demonstrate that the RTSA and ATSA implants have comparable results and can be expected to provide similar implant longevity over the midterm with excellent functional outcomes.
PMCID:7738444
PMID: 33345236
ISSN: 2666-6383
CID: 4903822

Ethical Implications of Resuming Elective Orthopedic Surgery During the COVID-19 Pandemic

Moses, Michael J.; Bosco, Joseph A.; Schwarzkopf, Ran; Zuckerman, Joseph D.; Long, William J.
The COVID-19 pandemic has had unprecedented impact on the United States health care system. One of the consider-ations was the decision to halt elective orthopedic surgery to preserve consumption of scarce resources. However, as the number of COVID-19 cases decrease, there will be discus-sions regarding the modality of resuming elective orthopedic surgery. Ethical considerations will come to the forefront in terms of determining the best course of action, patient selection, resource rationing, and financial implications. These factors will be examined through the lens of the four tenets of bioethics, beneficence, maleficence, autonomy, and justice, to elucidate the best approach in ethically manag-ing elective orthopedic surgery during a global pandemic.
PMID: 33207142
ISSN: 2328-5273
CID: 4708192

Impact of preoperative 3-dimensional planning and intraoperative navigation of shoulder arthroplasty on implant selection and operative time: a single surgeon's experience

Rosenthal, Yoav; Rettig, Samantha A; Virk, Mandeep S; Zuckerman, Joseph D
BACKGROUND:Preoperative 3D planning and intraoperative navigation for shoulder arthroplasty has recently gained interest because of the potential to enhance the surgeon's understanding of glenoid anatomy and improve the accuracy of glenoid component positioning. The purpose of our study was to assess the impact of preoperative 3D planning on the surgeon's selection of the glenoid component (standard vs. augmented) and compare duration of surgery with and without intraoperative navigation. METHODS:We retrospectively analyzed 200 consecutive patients who underwent shoulder arthroplasty. The first group of 100 patients underwent shoulder arthroplasty using standard 2D preoperative planning based on standard radiographs and computed tomographic scans. The second group of 100 patients underwent shoulder arthroplasty using 3D preoperative planning and intraoperative navigation. Type of glenoid component and operative time were recorded in each case. RESULTS:For the group of patients with standard preoperative planning, only 15 augmented glenoid components were used, whereas in the group of patients with 3D preoperative planning and navigation, 54 augments were used (P < .001). The operative time was 11 minutes longer for the procedures that used intraoperative navigation, compared with those that did not (P < .001). This difference diminished as the surgeon became more proficient with the navigation technique. CONCLUSION/CONCLUSIONS:Use of preoperative 3D planning changes the surgeon's understanding of the patient's glenoid anatomy. In our study, using 3D planning increased the likelihood that the surgeon selected an augmented glenoid component compared with 2D planning. Intraoperative navigation slightly lengthened the duration of surgery, but this became insignificant as part of a learning curve within 6 months.
PMID: 33190756
ISSN: 1532-6500
CID: 4671272