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Science. 1989:244(4909):1184-6.DOI: 10.1126/science.2658061

Amplification of a gene related to mammalian mdr genes in drug-resistant Plasmodium falciparum

Wilson, C M; Serrano, A E; Wasley, A; Bogenschutz, M P; Shankar, A H; Wirth, D F
The malaria parasite Plasmodium falciparum contains at least two genes related to the mammalian multiple drug resistance genes, and at least one of the P. falciparum genes is expressed at a higher level and is present in higher copy number in a strain that is resistant to multiple drugs than in a strain that is sensitive to the drugs.
PMID: 2658061
ISSN: 0036-8075
CID: 1478412