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Endovenous procedures in varicose veins What is the best choice today? [Review]
Kabnick, LS; Cayne, N; Jacobowitz, G; Lamparello, P; Maldonado, I; Rockman, C; Adelman, M
Over the post ten years endoveous treatment options for varicose veins have evovled considerably,offering clinicians a multitude of options to meet the needs of their patients. The endothermal oblation procedures have moved to the forefront as the choice modality for treating truncal reflux. Both radiofrequency ablation and endovenous loser ablation are widely accepted and interchangeable, showing comparable efficacy and safety. Although numerous endovenous loser wavelengths exist, the data indicates that the differences do not affect the efficacy or postoperative recovery of the procedure. The endovenous laser innovation that has shown early evidence of improved patient outcome is the jacket-tip fiber. The versatility of sclefotheropy makes it a critical component in the endovenous treatment of varicosities. Although not approved by the Food and Drug Administration (USA), the use of a foamed sclerosing agent is the fastest growing segment of sclerotherapy and an important treatment modality in the future of varicose vein treatment. Cutaneous losers and intense pulse light devices contribute a crucial element, enabling clinicians to treat minute veins that may be impossible to treat with other therapies
ISI:000261506200001
ISSN: 0939-978x
CID: 91326
Hemodynamic changes associated with carotid artery interventions
Cayne, Neal S; Rockman, Caron B; Maldonado, Thomas S; Adelman, Mark A; Lamparello, Patrick J; Veith, Frank J
Carotid artery interventions can be associated with adverse hemodynamic changes, including bradycardia and hypotension. These hemodynamic changes are believed to be caused by direct stimulation of the carotid sinus baroreceptors, mimicking normal physiological response to rises in blood pressure. During open carotid surgery, these hemodynamic changes can be controlled by direct injection of medications that block fast voltage gated sodium channels in the neuron cell membrane, thus preventing depolarization of the presynaptic neuron in the carotid sinus. This form of control is difficult or impossible during percutaneous carotid interventions because direct access to the carotid artery and carotid sinus is not available. This discussion focuses on the cause, effects, and possible treatments for the hemodynamic changes associated with carotid artery stenting procedures
PMID: 18930940
ISSN: 1531-0035
CID: 94023
Multidimensional characterization of carotid artery stenosis using CT imaging: a comparison with ultrasound grading and peak flow measurement
van Prehn, J; Muhs, B E; Pramanik, B; Ollenschleger, M; Rockman, C B; Cayne, N S; Adelman, M A; Jacobowitz, G R; Maldonado, T S
PURPOSE: Clinical decision making for carotid surgery depends largely upon stenosis grade. While digital subtraction angiography remains the gold standard for stenosis grading, many physicians use less invasive modalities. The purpose of this study was to compare the results of multidimensional Computed tomography (CTA) with ultrasound (US) grading and peak flow velocity (PSV). METHODS: 37 stenosed carotid arteries were studied retrospectively in 36 consecutive patients. US grading and PSV were compared to multidimensional CTA analysis (diameter, area and volumetric measurements), performed by a medical software company. Calculations of stenosis percentage on CTA were made using the NASCET and ECST methodology. Diameter measurements were also performed by a neuroradiologist. RESULTS: All CTA diameter, area and volume measurements had only modest correlation with PSV (r<0.5) and ultrasound grading (p<0.5). There was concordant classification of stenosis grades in only 40-60% of cases. CTA diameter, area and volume measurements had good correlation (0.69<r<0.87) with one another using ECST methodology. Using NASCET methodology on CTA, correlation between diameter and area was insignificant (r=0.32). CTA volumetric analysis with the NASCET method yielded 27 negative stenosis grades. Repeatability coefficient for selecting the normal distal ICA 20 mm more distally was 20% for diameter and 43% for area. CTA diameter interobserver repeatability coefficients were 22.9% (NASCET) and 17.8% (ECST) and 0.7 mm (lumen) and 1.9 mm (vessel). CONCLUSIONS: All CTA measurements showed moderate correlation with both ultrasound grading and PSV. Selection of the level of the normal distal ICA influences the NASCET calculations and can produce discrepant stenosis grades. Multidimensional CTA analysis seems to have no additional value for stenosis grading, but provides other useful anatomic information
PMID: 18585935
ISSN: 1532-2165
CID: 106167
Total Viabahn endoprosthesis collapse [Case Report]
Ranson, Mark E; Adelman, Mark A; Cayne, Neal S; Maldonado, Thomas S; Muhs, Bart E
We present a case of Viabahn (W. L. Gore & Associates, Flagstaff, Ariz) collapse during popliteal artery aneurysm treatment. An elderly man with severe comorbidities presented with a 34-mm popliteal artery aneurysm. Proximal and distal landing sites of 11 and 9 mm, respectively, demonstrated by preoperative computed tomography angiography were confirmed by intraoperative angiography. After Viabahn deployment, angiography revealed a filling defect in the distal popliteal graft with poor flow. Balloon dilatation failed. A femoropopliteal bypass with aneurysm ligation was performed. Transection of the distal popliteal vessel demonstrated complete infolding. Our choice of grafts represented 15% to 18% proximal and distal oversizing. Focal areas of relative vessel narrowing may lead to incomplete graft unfolding and graft failure
PMID: 18241770
ISSN: 0741-5214
CID: 76343
Use of a retrievable suprarenal inferior vena cava filter as a primary intervention for postpartum ovarian vein thrombosis: a case report [Case Report]
Sinha, Sara; Roman, Ashley S; Cayne, Neal S; Saltzberg, Stephanie; Rebarber, Andrei
BACKGROUND: Postpartum ovarian vein thrombosis is a rare diagnosis with a significant associated risk of pulmonary embolism. The mainstay of therapy consists of intravenous antibiotics and anticoagulation. CASE: A 30-year-old woman presented with fever and abdominal pain 3 days after cesarean section and was found to have an ovarian vein thrombosis on computed tomography. Given her history of cerebral arteriovenous malformation and the attendant risk for cerebral hemorrhage with the use of anticoagulation, she was successfully treated with a removable suprarenal inferior vena cava (IVC) filter and intravenous antibiotics. CONCLUSION: For patients who fail to respond to anticoagulation alone or in whom anticoagulation is contraindicated, placement of a retrievable suprarenal IVC filter is a viable treatment option in the setting of postpartum ovarian vein thrombosis
PMID: 18357807
ISSN: 0024-7758
CID: 76856
"Unpredictable" late rupture of an abdominal aortic aneurysm after bifurcated Ancure endograft repair [Case Report]
Rosen, Noah A; Cayne, Neal S; Macari, Michael; Jacobowitz, Glenn R
The goal of endovascular repair of an abdominal aortic aneurysm is to exclude the aneurysm from systemic arterial pressure, thereby preventing rupture. However, the long-term durability of endovascular repair continues to be in question, as aneurysm rupture after endovascular repair continues to be reported. We report the case of an 89-year-old patient who underwent endovascular repair of a 7.1-cm abdominal aortic aneurysm with an Ancure endograft 5 years earlier. Despite close follow-up and a shrinking aneurysm sac on annual contrast-enhanced computed tomography, he presented with aneurysm rupture and a new proximal type I endoleak. The endoleak and rupture were successfully repaired with endovascular placement of a main body extension
PMID: 18238872
ISSN: 1538-5744
CID: 78735
Regional nerve block allows for optimization of planning in the creation of arteriovenous access for hemodialysis by improving superficial venous dilatation
Laskowski, I A; Muhs, B; Rockman, C R; Adelman, M A; Ranson, M; Cayne, N S; Leivent, J A; Maldonado, T S
Durable vascular access for hemodialysis remains a critical issue in end-stage renal disease patients. Creation of an autogenous arteriovenous (AV) fistula in the most distal location of the nondominant extremity is the preferred technique and provides superior patency over an AV graft. Others have shown that regional anesthesia in the form of axillary block results in the dilatation of the native veins and allows for their increased utilization in creating AV fistulae. We report on 26 patients undergoing creation of a vascular access for hemodialysis. Regional anesthesia consisting of axillary nerve block was used in all cases. All surgical plans with regard to the site and type of access were made based on the physical exam and ultrasound vein measurements taken prior to surgery. On the day of surgery patients were reevaluated with venous ultrasound using tourniquet before and after administration of the regional block. The previously determined operative plan either remained unchanged or was modified depending on the venous dilatation noted after administration of regional block. Among 26 patients, average vein diameter increased from 0.29 +/- 0.12 cm to 0.34 +/- 0.11 cm (P = 0.008). Twenty-one of 26 patients had no modification in operative plan (group 1). Five had some modification of the original operative plan (group 2): AV graft to a brachial vein transposition (n = 2), AV graft to a Cimino fistula (n = 2), and brachiocephalic to a Cimino (n = 1). The average follow-up for all patients was 82.6 +/- 75.6 days and did not differ between the groups. There was one failure in a patient from group 1, and there was no significant difference in the patency rate between study groups (P = 0.29). Following regional nerve block, operative plans in patients undergoing AV access surgery were modified in 29.4% of patients undergoing creation of an AV access for hemodialysis; either from graft to fistula creation or from the proximal to more distal fistula site. The routine use of regional anesthesia as well as intraoperative ultrasound during AV access surgery can lead to improved site selection and increased opportunity for AV fistula creation
PMID: 17703918
ISSN: 0890-5096
CID: 75652
Decreased ischemic complications after endovascular aortic aneurysm repair with newer devices
Maldonado, Thomas S; Ranson, Mark E; Rockman, Caron B; Pua, Brad; Cayne, Neal S; Jacobowitz, Glenn R; Adelman, Mark A
Ischemic complications after endovascular abdominal aortic aneurysm repair (EVAR) are well-recognized and have been reported to be as high as 9%. The goal of our study was to examine the incidence, management, and outcome of ischemic complications at our institution after EVAR and to compare complications according to graft type and time period. This is a retrospective review of all EVARs performed at our institution from 1993 through 2005 (n = 430). EVAR was performed in asymptomatic patients in most cases. Follow-up consisted of a computed tomography scan and office visit at 1, 6, and 12 months and yearly thereafter. Ischemic complications after EVAR have decreased significantly with the advent of lower-profile devices with easier delivery systems and supported limbs. Simultaneous coil embolization of internal iliac artery at the time of EVAR implant does not appear to increase the risk of pelvic or lower-extremity ischemia, can be done safely, and does not need to be staged
PMID: 17595384
ISSN: 1538-5744
CID: 73863
Early carotid endarterectomy in symptomatic patients is associated with poorer perioperative outcomes
Rockman, Caron B; Maldonado, Thomas S; Jacobowitz, Glenn R; Cayne, Neal S; Gagne, Paul J; Riles, Thomas S
OBJECTIVE: The optimal timing of carotid endarterectomy (CEA) after ipsilateral hemispheric stroke is controversial. Although early studies suggested that an interval of about 6 weeks after a completed stroke was preferred, more recent data have suggested that delaying CEA for this period of time is not necessary. With these issues in mind, we reviewed our experience to examine perioperative outcome with respect to the timing of CEA in previously symptomatic patients. METHODS: A retrospective review of a prospectively maintained database of all CEAs performed at our institution from 1992 to 2003 showed that 2537 CEA were performed, of which 1,158 (45.6%) were in symptomatic patients. Patients who were operated on emergently <or=48 hours of symptoms for crescendo transient ischemic attacks (TIAs) or stroke-in-evolution were excluded from analysis (n = 25). CEA was considered 'early' if performed <or=4 weeks of symptoms, and 'delayed' if performed after a minimum of a 4-week interval following the most recent symptom. RESULTS: Of nonurgent CEAs in symptomatic patients, in 87 instances the exact time interval from symptoms to surgery could not be precisely determined secondary to the remoteness of the symptoms (>18 months), and these were excluded from further analysis. Of the remaining 1,046 cases, 62.7% had TIAs and 37.3% had completed strokes as their indication for surgery. Among the entire cohort, patients who underwent early CEA were significantly more likely to experience a perioperative stroke than patients who underwent delayed CEA (5.1% vs 1.6%, P = .002). Patients with TIAs alone were more likely to be operated on early rather than in a delayed fashion (64.3% vs 46.7%, P < .0001), likely reflecting institutional bias in selecting delayed CEA for stroke patients. However, even when examined as two separate groups, both TIA patients (n = 656) and CVA patients (n = 390) were significantly more likely to experience a perioperative stroke when operated upon early rather than in a delayed fashion (TIA patients, 3.3% vs 0.9%, P = .05; CVA patients, 9.4% vs 2.4%, P = .003). There were no significant differences in demographics or other meaningful variables between patients who underwent early CEA and those who underwent delayed CEA. CONCLUSIONS: In a large institutional experience, patients who underwent CEA <or=4 weeks of ipsilateral TIA or stroke experienced a significantly increased rate of perioperative stroke compared with patients who underwent CEA in a more delayed fashion. This was true for both TIA and stroke patients, although the results were more impressive among stroke patients. On the basis of these results, we continue to recommend that waiting period of 4 weeks be considered in stroke patients who are candidates for CEA
PMID: 16844338
ISSN: 0741-5214
CID: 68644
Interval gangrene complicating superficial femoral artery stem placement (vol 42, pg 564, 2005) [Correction]
Pua, BB; Muhs, BF; Parikh, MS; Cayne, N; Lamparello, PJ
ISI:000233949300042
ISSN: 0741-5214
CID: 2725972