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How to diagnose and treat abdominal compartment syndrome after endovascular and open repair of ruptured abdominal aortic aneurysms

Mayer, D; Rancic, Z; Veith, F J; Pecoraro, F; Pfammatter, T; Lachat, M
Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are frequently encountered in patients treated for ruptured abdominal aortic aneurysms (rAAA) and carry a high morbidity and mortality risk. Despite these facts, IAH/ACS are still overlooked by many physicians, timely diagnosis is missed and treatment often inadequate. All staff involved in the treatment of rAAA should be aware of the risk factors predicting IAH/ACS, the profound implications and derangements on all organ systems, the clinical presentation, the appropriate measurement of intra-abdominal pressure to detect IAH/ACS and the current treatment options for these detrimental syndromes. This comprehensive review provides contemporary knowledge that should help to improve patient survival and long-term outcome.
PMID: 24670826
ISSN: 0021-9509
CID: 1057992

Carotid artery stenting: it's all about appropriate patient selection and keeping to the indications

Paraskevas, Kosmas I; Beard, Jonathan D; Veith, Frank J
With increasing carotid artery stenting (CAS) expertise and improved CAS equipment, recent trials have demonstrated better results for CAS compared with earlier studies. As a result, it may be argued that CAS is currently non-inferior to carotid endarterectomy (CEA), at least in some patient subgroups. Consequently, there have been recent calls for extending CAS indications to include average surgical risk patients with symptomatic or asymptomatic carotid stenosis. However, CAS remains a less cost-effective option than CEA. Opening the floodgates to unrestricted CAS for both symptomatic and asymptomatic carotid patients would have considerable cost implications for any health system. Appropriate patient selection and keeping to the indications are crucial to optimize CAS outcomes.
PMID: 24949800
ISSN: 1477-9072
CID: 1050722

Regarding "Progression of asymptomatic carotid stenosis despite optimal medical therapy" [Letter]

Abbott, Anne; Geroulakos, George; Mikhailidis, Dimitri P; Nicolaides, Andrew N; Sillesen, Henrik; Veith, Frank J
PMID: 24836773
ISSN: 0741-5214
CID: 1003522

Paraincisional subcutaneous infusion of ropivacaine after open abdominal vascular surgery shows significant advantages

Chaykovska, Lyubov; Blohme, Linus; Mayer, Dieter; Gloekler, Steffen; Rancic, Zoran; Schmidt, Christian A P; Tunesi, Roberto; Veith, Frank; Lachat, Mario; Bettex, Dominique
BACKGROUND: Opiates are widely used for postoperative pain relief. Unfortunately, their side effects such as inhibited gastrointestinal motility and respiratory depression may compromise or delay postoperative recovery after laparotomy. We used paraincisional subcutaneous catheters (PSCs) and applied 0.25% ropivacaine infusion to improve pain relief and decrease postoperative morphine consumption in patients after open surgery for aortic aneurysm. METHODS: A retrospective single-center study including 58 patients treated by open surgery for aortic aneurysm between October 2006 and June 2012. Overall, 28 patients (control group) received standard postoperative pain management including opiates, and 30 patients (PSC group) were treated with paraincisional continuous local analgesia with 0.25% ropivacaine administrated via bilateral subcutaneous catheters along with additional ad libitum opiates administration, at first intravenously and then orally. RESULTS: Patients characteristics as well as perioperative and postoperative outcomes were comparable between the groups during the first 5 days after surgery. Patients of the PSC group received significantly less morphine, although the patients in both groups reported a similar pain intensity. Neither wound-healing disorder nor catheter-associated subcutaneous infection was reported. High serum concentration of ropivacaine was detected in 2 patients (6%) with end-stage renal disease, who developed temporary neurologic symptoms. Length of intensive care unit (ICU) stay was significantly shorter in the PSC group (2 [0-23] vs. 4.5 [0-32] ICU days). CONCLUSIONS: This is the first report about PSCs for analgesia after laparotomy. This case/control study shows that continuous paraincisional subcutaneous infusion of 0.25% ropivacaine after open surgery for aortic aneurysm repair is a feasible method of postoperative analgesia. This technique allows sustained pain relief with significant reduction of opiate requirement and faster recovery after surgery. Prospective randomized controlled trial is necessary for the assessment of safety and efficacy of this method.
PMID: 24456863
ISSN: 0890-5096
CID: 969892

Implications of the timely diagnosis of lower extremity peripheral arterial disease

Paraskevas, Kosmas I; Mikhailidis, Dimitri P; Giannoukas, Athanasios D; Veith, Frank J
PMID: 24703803
ISSN: 0167-5273
CID: 898992

Commentary: carotid artery stenting: still not as cost-effective as carotid endarterectomy, but the contest continues

Paraskevas, Kosmas I; Moore, Wesley S; Veith, Frank J
PMID: 24754291
ISSN: 1526-6028
CID: 899002

Optimal management of patients with symptomatic and asymptomatic carotid artery stenosis: work in progress

Paraskevas, Kosmas I; Abbott, Anne L; Veith, Frank J
The optimal management of patients with symptomatic and asymptomatic carotid artery stenosis remains a subject of extensive debate. Several international societies and associations have published guidelines for the management of carotid patients. Although these recommendations are based on the same randomized trials, differences in interpretation of available knowledge have often led to different (or even conflicting) recommendations. This special report summarizes the current evidence-based optimal management of patients with symptomatic and asymptomatic carotid stenosis and compares key international guidelines. Finally, issues requiring further research are identified and discussed.
PMID: 24597958
ISSN: 1477-9072
CID: 898982

Chimney and periscope grafts to facilitate endovascular treatment of aortic transection in a patient with aberrant right subclavian artery

Vicente, Sandra; Glenck, Michael; Mayer, Dieter; Veith, Frank J; Lachat, Mario; Pecoraro, Felice
Purpose : To report the use of parallel grafts to extend the proximal landing zone for stent-graft repair of aortic transection involving an aberrant right subclavian artery (ARSA). Case Report : A 28-year-old patient was referred for treatment of traumatic aortic transection with contained rupture at the level of an ARSA. Immediate thoracic endovascular aortic repair (TEVAR) was planned because of hemodynamic instability. To achieve rapid sealing and maintain perfusion to both subclavian arteries, a chimney stent to the left subclavian artery (LSA) and a periscope stent-graft to the ARSA were deployed successfully. After surgical repair of all fractures, the patient was discharged 1 month after the initial injury in good condition. Imaging follow-up at 10 months showed a stable repair, patent parallel grafts, and no complications. Conclusion : TEVAR with chimney and periscope grafts proved to be a safe and quick treatment for a patient requiring ARSA repair in acute aortic transection. This technique maintained blood flow to the ARSA and LSA in a totally endovascular approach, which could be very valuable in transection cases where bypass surgery to supra-aortic branches is compromised or deemed challenging due to thoracic wall and/or neck trauma. Parallel grafting can be a valuable tool to address any acute aortic pathology as it can be performed with off-the-shelf devices.
PMID: 24502492
ISSN: 1526-6028
CID: 833692

Treatment options for asymptomatic carotid artery stenosis [Letter]

Paraskevas, Kosmas I; Veith, Frank J
PMID: 24496542
ISSN: 0098-7484
CID: 800142

Early endovascular grafts at Montefiore Hospital and their effect on vascular surgery

Veith, Frank J; Cynamon, Jacob; Schonholz, Claudio J; Parodi, Juan C
Vascular surgery is very fortunate. It recognized the transition from open surgery to endovascular procedures as treatments for vascular disease early enough to adapt as a specialty. As a result, most vascular surgeons in North America became competent with endovascular techniques, and the survival of the specialty was assured. The endovascular graft program at Montefiore Hospital played a major role in vascular surgery's early recognition of the importance of the endovascular revolution. This article will review the history of this early endovascular graft program and how it influenced the specialty.
PMID: 24360581
ISSN: 0741-5214
CID: 737942