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Major depressive disorder, when under treatment, may not affect functional outcomes in patients with tibial plateau fractures

Perskin, Cody R; Maseda, Meghan; Konda, Sanjit R; Ganta, Abhishek; Egol, Kenneth A
BACKGROUND:The purpose of this study is to determine if treated psychological depression is associated with poorer functional outcomes in patients who sustain tibial plateau fractures. METHODS:Patients with a tibia plateau fracture were prospectively followed. Functional status was assessed using the Short Musculoskeletal Function Assessment (SMFA) at baseline (pre-injury), 3 months, 6 months, and 1 year post injury. Clinical outcomes were recorded at each follow up visit and radiographic outcomes were obtained from follow up radiographs. Records were reviewed to identify patients who were being treated for major depressive disorder (MDD). SMFA scores and clinical outcomes were compared between the depression and no depression cohorts. RESULTS:420 patients were treated for a tibial plateau fracture and the mean age was 50.83 ± 15.60 years. Forty-two (10%) patients with 42 fractures were being treated for MDD at the time of their fracture. Patients with MDD were older (p = 0.05) and were more likely female (p < 0.01). At baseline, the clinical depression cohort had worse Total SMFA scores compared to the non-depressed cohort (5.90 ± 14.41 vs. 2.69 ± 8.35, p < 0.01). There were no differences in total SMFA score or any SMFA subscores at 3, 6, and 12 months. The incidence of wound complications, reoperations, and radiographic outcomes also did not differ between the cohorts. CONCLUSION/CONCLUSIONS:Despite patients with MDD reporting higher SMFA (poorer) scores at baseline, MDD was not associated with worse injuries, diminished clinical or poorer functional outcomes following tibial plateau fractures.
PMID: 34920233
ISSN: 1873-5800
CID: 5109922

"Damage Control" Fixation of Displaced Femoral Neck Fractures in High-Risk Elderly Patients: A Feasibility Case Series

Konda, Sanjit R; Dedhia, Nicket; Rettig, Samantha; Davidovitch, Roy; Ganta, Abhishek; Egol, Kenneth A
OBJECTIVES/OBJECTIVE:To assess the outcomes of patients who underwent closed reduction and percutaneous pinning (CRPP) with cannulated screws for treatment of a displaced femoral neck fracture (DFNF) as they were deemed too high risk to undergo hemiarthroplasty (HA). DESIGN/METHODS:Prospective cohort study. SETTING/METHODS:One urban academic medical center. PATIENTS/PARTICIPANTS/METHODS:Sixteen patients treated with CRPP and 32 risk-level-matched patients treated with HA. INTERVENTION/METHODS:CRPP for patients with DFNFs who were deemed too ill to undergo HA. The concept being that CRPP would aid in pain control and facilitate mobilization and if failed, the patient could return electively after medical optimization for conversion to arthroplasty. MAIN OUTCOME MEASUREMENTS/METHODS:Complications, readmissions, mortality, inpatient cost, and functional status. RESULTS:The CRPP cohort had a greater incidence of exacerbations of chronic medical conditions or new onset of acute illness and an elevated mean American Society of Anesthesiologist score. There were no differences in discharge location, length of stay, major complication rate, ambulation before discharge, or 90-day readmission rate. Patients undergoing CRPP were less likely to experience minor complications including a significantly decreased incidence of acute blood loss anemia. Three patients (18.7%) in the CRPP cohort underwent conversion to HA or THA. There was no difference in inpatient, 30-day, or 1-year mortality. CONCLUSION/CONCLUSIONS:In the acutely ill patients with DFNFs, "damage control" fixation with CRPP can be safely performed in lieu of HA to stabilize the fracture in those unable to tolerate anesthesia or the sequelae of major surgery. Patients should be followed closely to evaluate the need for secondary surgery. LEVEL OF EVIDENCE/METHODS:Therapeutic Level III. See Instructions for Authors for a complete description of Levels of Evidence.
PMID: 34369455
ISSN: 1531-2291
CID: 5074532

Risk factors and associated outcomes of acute kidney injury in hip fracture patients

Ganta, Abhishek; Parola, Rown; Perskin, Cody R; Konda, Sanjit R; Egol, Kenneth A
Purpose/UNASSIGNED:To assess risk factors and associated outcomes of acute kidney injury (AKI) in hip fracture patients. Methods/UNASSIGNED:Risk factors for AKI were identified by multivariate logistic regression. AKI patients were matched to patients who did not experience AKI using a validated trauma triage score. Comparative analyses between matched groups were performed. Results/UNASSIGNED:Risk factors of AKI included increasing Charlson Comorbidity Index and use of anticoagulation medications. AKI was associated with increased likelihood of medical complications and longer, more costly hospital stays. Discussion/UNASSIGNED:
PMCID:8335623
PMID: 34385809
ISSN: 0972-978x
CID: 5006252

Trauma Risk Score Also Predicts Blood Transfusion Requirements in Hip Fracture Patients

Konda, Sanjit R; Perskin, Cody R; Parola, Rown; Robitsek, R Jonathan; Ganta, Abhishek; Egol, Kenneth A
Introduction/UNASSIGNED:The purpose of this study is to determine if the risk of receiving a blood transfusion during hip fracture hospitalization can be predicted by a validated risk profiling score (Score for Trauma Triage in Geriatric and Middle Aged (STTGMA)). Materials and Methods/UNASSIGNED:A consecutive series of 1449 patients 55 years and older admitted for a hip fracture at one academic medical center were identified from a trauma database. The STTGMA risk score was calculated for each patient. Patients were stratified into risk groups based on their STTGMA score quantile: minimal risk (0-50%), low risk (50-80%), moderate risk (80-95%), and high risk (95-100%). Incidence and volume of blood transfusions were compared between risk groups. Results/UNASSIGNED:< 0.001). STTGMA was predictive of first transfusion incidence in both the preoperative and postoperative periods. There was no difference in mean total transfusion volume between the four risk groups. Conclusion/UNASSIGNED:The STTGMA model is capable of risk stratifying hip fracture patients more likely to receive blood transfusions during hospitalization. Surgeons can use this tool to anticipate transfusion requirements.
PMCID:8361552
PMID: 34395049
ISSN: 2151-4585
CID: 5006322

Monitored Anesthesia Care and Soft-Tissue Infiltration with Local Anesthesia (MAC-STILA): An Anesthetic Option for High Risk Patients with Hip Fractures

Konda, Sanjit R; Ranson, Rachel A; Dedhia, Nicket; Tong, Yixuan; Saint-Cyrus, Evens; Ganta, Abhishek; Egol, Kenneth A
OBJECTIVES/OBJECTIVE:To examine the feasibility of a novel anesthetic option for hip fracture fixation with short cephalomedullary nails. DESIGN/METHODS:Retrospective cohort study. SETTING/METHODS:An urban, academic level 1 trauma center, a tertiary care academic medical center, and an orthopedic specialty hospitalPatients/Participants: 20 recent and 40 risk-matched (1:1:1 by anesthesia type) historical hip fracture patients. INTERVENTION/METHODS:All patients with an OTA 31.A1-3 IT hip fracture presenting from October 1st 2019 - March 31st, 2020 treated with a short cephalomedullary nail (CMN) underwent a new intraoperative anesthesia protocol using monitored anesthesia care (MAC) and soft-tissue infiltration with local anesthesia (STILA). MAIN OUTCOME MEASUREMENTS/METHODS:Intraoperative measures, postoperative pain scores, narcotic and acetaminophen use, hospital quality measures, and inpatient cost. RESULTS:A total of 60 patients (20 each: MAC, general, spinal) were identified. There were differences among the groups regarding mean minimum and maximum intraoperative heart rate with MAC-STILA protocol demonstrating the best maintenance of normal heart rate parameters (60-100 bpm). For the first 3 hours post-operatively, MAC-STILA patients reported consistently lower pain scores (VAS <1) than spinal or general patients (VAS>1). Through 48 hours postoperatively, MAC-STILA narcotic usage was similar to that of the spinal cohort and approximately five times less than the general cohort. There were no differences in procedural time, length of stay, minor or major complications, inpatient and 30-day mortality, or 30-day readmissions, or post-operative ambulatory distance. There was no difference in inpatient cost among cohorts. CONCLUSIONS:This feasibility study demonstrates safety for the MAC-STILA protocol with comparison to spinal and general anesthesia. The MAC-STILA protocol is a viable option for treatment of OTA 13.A1-3 IT fractures with a short CMN, and may be the preferred method for patients with severe medical co-morbidities or relative contraindications to general and/or spinal anesthesia. LEVEL OF EVIDENCE/METHODS:Therapeutic Level III. See Instructions for Authors for a complete description of Levels of Evidence.
PMID: 33967226
ISSN: 1531-2291
CID: 4867052

Loss of Ambulatory Level and Activities of Daily Living at 1 Year Following Hip Fracture: Can We Identify Patients at Risk?

Konda, Sanjit R; Dedhia, Nicket; Ranson, Rachel A; Tong, Yixuan; Ganta, Abhishek; Egol, Kenneth A
Introduction/UNASSIGNED:Operative hip fractures are known to cause a loss in functional status in the elderly. While several studies exist demonstrating the association between age, pre-injury functioning, and comorbidities related to this loss of function, no studies have predicted this using a validated risk stratification tool. We attempt to use the Score for Trauma Triage for Geriatric and Middle-Aged (STTGMA) tool to predict loss of ambulatory function and need for assistive device use. Materials and Methods/UNASSIGNED:Five hundred and fifty-six patients ≥55 years of age who underwent operative hip fracture fixation were enrolled in a trauma registry. Demographics, functional status, injury severity, and hospital course were used to determine a STTGMA score and patients were stratified into risk quartiles. At least 1 year after hospitalization, patients completed the EQ-5D questionnaire for functional outcomes. Results/UNASSIGNED:Two hundred and sixty-eight (48.2%) patients or their family members responded to the questionnaire. Of the 184 patients alive, 65 (35.3%) reported a return to baseline function. Eighty-nine (48.4%) patients reported a loss in ambulatory status. Patients with higher STTGMA scores were older, had more comorbidities, reported greater need for help with daily activities, increased difficulty with self-care, and a reduction in return to activities of daily living (all p ≤ 0.001). Patients with lower STTGMA scores were more likely to never require an assistive device while those with higher scores were more likely to continue needing one (p = 0.004 and p < 0.001). Patients in the highest STTGMA risk groups were 1.5x more likely to have an impairment in ambulatory status (need for ambulatory assistive device or decreased ambulatory capacity) (p = 0.004). Discussion/UNASSIGNED:Patients in higher STTGMA risk quartiles were more likely to experience impairment after hip fracture surgery. The STTGMA tool can predict loss of ambulatory independence following hip fracture. At-risk populations can be targeted for enhanced physiotherapy and rehabilitation services for optimal return to prior functioning.
PMCID:8020397
PMID: 33868763
ISSN: 2151-4585
CID: 4846632

Is There Value in Early Postoperative Visits Following Hip Fracture Surgery?

Ganta, Abhishek; Dedhia, Nicket; Ranson, Rachel A; Robitsek, Jonathan; Hsu, Joseph R; Konda, Sanjit R; Egol, Kenneth A
Introduction/UNASSIGNED:Despite the recommendation for postoperative orthopedic follow-up after a hip fracture in elderly patients, many patients do not return for these visits. In this study, we attempt to determine if early follow-up (<4 weeks post-discharge) changes orthopedic post-operative management. Materials and Methods/UNASSIGNED:1232 patients aged > 55 years old who underwent operative fixation for hip fractures were enrolled into an orthopedic trauma registry and followed from hospitalization through one year. Demographics, comorbidities, injury severity, and hospital course data were collected. Need for readmission and orthopedic follow-up were ascertained through chart review. Results/UNASSIGNED:417 patients (33.8%) patients did not return for any follow-up and 30 (2.4%) patients died <30 days from discharge. 370 (45.5%) patients had early orthopedic follow-up ≤28 days after discharge. 317 (38.9%) patients were seen ≥29 days after discharge (late follow-up). 127 (15.6%) patients returned for isolated non-orthopedic care. There were 23 (6.2%) readmissions in the early group, 17 (5.4%) in the late group, and 24 (18.9%) in the no follow-up group (p < 0.001). Patients discharged home were more likely to present for early follow-up compared to those with late and non-orthopedic follow-up (p = 0.002), however there was no difference in readmission rates between those discharged home vs. SNFs/SARs. Discussion/UNASSIGNED:Patients who received isolated non-orthopedic follow-up within 4 weeks of surgery experienced more hospital readmissions than those with follow-up in that time period; however, these readmissions were primarily due to medical issues. There was no difference in orthopedic-related readmissions and changes in orthopedic management between groups. Patients discharged to SNFs/SARs did not present for early orthopedic as often as those discharged home. Conclusion/UNASSIGNED:Early orthopedic follow up after hip fracture care does not change post-operative management in these patients and has implications for value-based care. Level of Evidence/UNASSIGNED:Prognostic Level III.
PMCID:7890718
PMID: 33643678
ISSN: 2151-4585
CID: 4799962

Hip Fracture Volume Does Not Change at a New York City Level 1 Trauma Center During a Period of Social Distancing

Haskel, Jonathan D; Lin, Charles C; Kaplan, Daniel J; Dankert, John F; Merkow, David; Crespo, Alexander; Behery, Omar; Ganta, Abhishek; Konda, Sanjit R
Purpose/UNASSIGNED:To characterize the volume and variation in orthopedic consults and surgeries that took place during a period of social distancing and pandemic. Methods/UNASSIGNED:All orthopedic consults and surgeries at an urban level 1 trauma center from 3/22/20-4/30/2020 were retrospectively reviewed (the social distancing period). Data from the same dates in 2019 were reviewed for comparison. Age, gender, Score for Trauma Triage in the Geriatric and Middle Aged (STTGMA) score and injury type were queried. Operating room data collected included: type of surgery performed, inpatient or outpatient status, and if the cases were categorized as elective, trauma or infectious cases. Results/UNASSIGNED:Compared to 2019, there was a 48.3% decrease in consult volume in 2020. The 2020 population was significantly older (44.0 vs 52.6 years-old, p = 0.001) and more male (65% vs 35%, p = 0.021). There were 23 COVID positive patients, 10 of which died within the collection period. Consult distribution dramatically changed, with decreases in ankle fractures, distal radius fractures and proximal humerus fractures of 76.5%, 77.4% and 55.0%, respectively. However, there was no significant difference in volume of hip, tibial shaft and femoral shaft fractures (p > 0.05). In 2020, there was a 41.4% decrease in operating room volume, no elective cases were performed, and cases were primarily trauma related. Conclusions/UNASSIGNED:During a period of pandemic and social distancing, the overall volume of orthopedic consults and surgeries significantly declined. However, hip fracture volume remained unchanged. Patients presenting with orthopedic injuries were older, and at higher risk for inpatient mortality.
PMCID:7672735
PMID: 33240558
ISSN: 2151-4585
CID: 4679252

Postoperative Inpatient Conversions Following Ambulatory Orthopedic Surgery

Gonzalez, Matthew; Ganta, Abhishek; Sapienza, Anthony
BACKGROUND:Despite the recent trend toward outpatient orthopedic surgical procedures, there are patients who incur unanticipated conversions to inpatient status either immediately following ambulatory surgery or within days to weeks via presentation to the emergency department. The purpose of this study was to examine characteristics, co-morbidities, and causes of admissions in these populations in order to help identify factors for which strategies can be developed in order to minimize unanticipated admissions and medical costs. METHODS:Using a major academic medical center's bill-ing department's database, 95 outpatients were identified who were immediately converted into inpatient status and another 84 outpatients who were admitted within 30 days of surgery. The reasons for admission, length of procedure, length of admission, ASA score, comorbidities, and insur-ance type were assessed. RESULTS:For the patients who were converted to inpa-tient status postoperatively, pain accounted for 57% of conversions. Hypertension was the most commonly seen comorbidity (44%). In patients admitted within 30 days of ambulatory surgery, infection (25%) was the most common cause of admission. Smoking (46.4%) represented the most common comorbidity in this cohort. CONCLUSIONS:The majority of immediate inpatient con-versions were due to pain, emphasizing the need to optimize perioperative analgesia and provide impactful patient education regarding postoperative pain expectations. For patients admitted within 30 days of surgery, infection represented the majority of readmissions, and smoking was the most common comorbidity. While, some infections may be unavoidable, this stresses the importance of medical and social factor optimization prior to surgery. Addressing these factors leading to unanticipated admissions can have a profound effect on health care expenditures and patient outcomes.
PMID: 33207147
ISSN: 2328-5273
CID: 4672822

Who Is the Geriatric Trauma Patient? An Analysis of Patient Characteristics, Hospital Quality Measures, and Inpatient Cost

Konda, Sanjit R; Lott, Ariana; Mandel, Jessica; Lyon, Thomas R; Robitsek, Jonathan; Ganta, Abhishek; Egol, Kenneth A
Purpose/UNASSIGNED:The purpose of this study was 2-fold: 1) to investigate the age-related frequency, demographics and distribution of the middle-aged and geriatric orthopedic trauma population and 2) to describe the age-related frequency and distribution of hospital quality measure outcomes and inpatient cost. Methods/UNASSIGNED:All patients > 55 years of age who required orthopedic, trauma, or neurosurgery consults at 3 hospitals within an academic medical center from 2014 to 2017 were prospectively followed. On initial evaluation, each patient's demographics, injury severity, and functional status were collected. Patients were grouped into low and high-energy mechanism cohorts and divided into 5 groups based on age. Hospital quality measures including length of stay, complications, discharge location, and cost of care was compared between age groups. Data were analyzed using ANOVA and Chi-square tests. Results/UNASSIGNED:A total of 3965 patients were included in this study of which 3268 (82%) sustained low-energy trauma and 697 (18%) sustained high-energy trauma. With increasing age, more patients had more comorbidities, were less likely to be community ambulators, and more likely to use assistive devices (p < 0.05). Patients in older age groups had longer lengths of stay, more complications, were more likely to need ICU level care, and were less likely to be discharged home (p < 0.05). Rates of mortality were also greater in patients of more advanced age in both low and high-energy cohorts, and the calculated risk triage tool (STTGMA) score increased with each age bracket (p < 0.05). Total cost of care differed between age groups in the low-energy cohort (p = 0.003). Conclusion/UNASSIGNED:This epidemiological study provides a clear picture of the frequency and distribution of demographic, physiologic characteristics, outcomes, and cost of care in a middle-aged and geriatric orthopedic trauma population as evaluated by the STTGMA risk tool. Risk profiling of geriatric trauma patients allows for the establishment of baseline norms.
PMCID:7495933
PMID: 32974077
ISSN: 2151-4585
CID: 4606002