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202


CT appearance of isolated dextroversion [Case Report]

Maldjian, Pierre D; Saric, Muhamed; Anis, Ather
We present the multidetector CT appearance of a case of isolated dextroversion. Dextroversion is a rare anomaly characterized by extreme right-sided rotation of the heart resulting in dextrocardia with the left ventricle anterior and to the left of the right ventricle. The diagnosis is easily made with ECG-gated multidetector CT
PMID: 16645787
ISSN: 1569-5794
CID: 102219

Severe chronic aortic insufficiency requiring valve replacement: an infrequent complication of Takayasu's disease [Case Report]

Brady, Jennifer; Esrig, Barry C; Hamirani, Kamran; Baisre, Ada; Saric, Muhamed
Takayasu's arteritis (TA) is a granulomatous vasculitis of medium and large arteries, which most often presents as pulseless disease due to widespread arterial stenoses. Only the minority of TA patients have aortic valve insufficiency, which is due to aortic root dilatation following aortitis and aneurysm formation. No other cardiac valve is involved. We report a case of Takayasu's disease-related severe aortic insufficiency (AI) in a Filipino woman, which necessitated aortic valve replacement. It is important to consider TA in the differential diagnosis of AI in young women, particularly those with early-onset systemic hypertension and pulse deficits. Early diagnosis and therapy of TA can improve outcomes
PMID: 16839388
ISSN: 0742-2822
CID: 102217

Radiological reasoning: pulmonary embolism--thinking beyond the clots [Case Report]

Maldjian, Pierre D; Anis, Ather; Saric, Muhamed
OBJECTIVE: We discuss the CT findings in a case of pulmonary embolism complicated by paradoxical embolism in a patient with a patent foramen ovale and atrial septal aneurysm. CONCLUSION: When confronted with a case of pulmonary embolism on CT, besides evaluating the extent of pulmonary artery occlusion, the radiologist should examine the cardiovascular system to identify any unsuspected underlying or associated conditions
PMID: 16498137
ISSN: 0361-803x
CID: 102220

A comparison of nesiritide vs. epoprostenol in a patient with precapillary pulmonary hypertension due to scleroderma complicated by postcapillary pulmonary hypertension [Case Report]

Zakir, Ramzan M; Berkowitz, Robert L; Saric, Muhamed; Ashtyani, Hormoz
To the best of our knowledge, acute decompensated left-sided heart failure with preserved left ventricular ejection fraction in a patient with scleroderma has not been previously reported. We describe a patient with severe pulmonary hypertension due to limited scleroderma in whom nesiritide led to marked reductions in pulmonary arterial and capillary wedge pressure as well as resolution of symptoms and pulmonary edema. Subsequent epoprostenol use was associated with an increase in pulmonary capillary wedge pressure and a recurrence of pulmonary edema. Thus, nesiritide may be the preferred agent in scleroderma patients with severe pulmonary hypertension and preserved left ventricular systolic function since epoprostenol may lead to adverse hemodynamic effects
PMID: 16330910
ISSN: 1527-5299
CID: 102221

Fatal ascending aorta-to-right ventricle fistula formation after Staphylococcus aureus endocarditis of bicuspid aortic valve [Case Report]

Coleman, Jakemia M; Haider, Bunyad; Cuyjet, Aloysius B; Zakir, Ramzan M; Riauba, Linas; Saric, Muhamed
We present a case of a 46-year-old man with advanced acquired immunodeficiency syndrome and congenitally bicuspid aortic valve endocarditis caused by methicillin- and gentamicin-resistant Staphylococcus aureus. Endocarditis led to root abscess formation, a complete heart block, and fistulous tract formation between the ascending aorta and the right ventricle. Although perivalvular abscess is not an unusual complication of native valve endocarditis, a fatal fistulous communication between the ascending aorta and the right ventricle is exceedingly rare
PMID: 16324963
ISSN: 0147-9563
CID: 102222

Quadricuspid aortic valve with four equal cusps in a quinquagenarian [Case Report]

Patel, Rajiv J; Patel, Jayant N; Zakir, Ramzan M; Apovian, John; Stakhyra, Iryna; Dabu, Leticia; Saric, Muhamed
PMID: 16276133
ISSN: 1076-7460
CID: 102223

Papillary fibroelastoma: an uncommon cause for a transient ischemic attack [Case Report]

Anis, Ather; Brady, Jennifer; Sedaghat, David; Klapholz, Mark; Esrig, Barry C; Saric, Muhamed
PMID: 16247287
ISSN: 1076-7460
CID: 102225

Catheter-based aortography fails to identify aortic atherosclerotic lesions detected on transesophageal echocardiography

Khatri, Ismail A; Mian, Nimer; Alkawi, Ammar; Janjua, Nazli; Kirmani, Jawad F; Saric, Muhamed; Levine, Jason C; Qureshi, Adnan I
BACKGROUND AND PURPOSE: Transesophageal echocardiography is used to detect the aortic arch pathology during diagnostic workup of ischemic stroke events. Conventional angiography is increasingly used in diagnosing and treating atherosclerotic vascular lesions in patients with ischemic stroke. Although catheter-based aortography can be performed with cerebral angiography, there is limited information about the utility of aortography in identifying atherosclerotic abnormalities of the aortic arch. METHODS: A retrospective chart review was performed to identify patients who underwent aortography as part of their angio-graphic study and transesophageal echocardiography. Both studies were reviewed independently in the absence of knowledge of the results of the other study. The findings of these aortograms were correlated with the findings of transesophageal echocardiography. RESULTS: A total of 34 patients underwent both aortography and echocardiography. Of a total of 34 trans esophageal echocardiograms, 29 showed abnormal findings in the aorta (85%) and 5 appeared normal (15%). These aortic abnormalities included mild to moderate atherosclerosis in 18 cases (52%), moderate to severe atherosclerosis in 4 cases (12%), and severe atherosclerosis in 7 cases (21%). None of these abnormalities were detected by aortography. No disease was visualized in the origin of the supraaortic arteries. CONCLUSIONS: Aortic arch atherosclerosis is common in patients with ischemic stroke; however, aortograms acquired during conventional angiography fail to identify abnormalities detected on transesophageal echocardiogram
PMID: 15951409
ISSN: 1051-2284
CID: 102226

The patient with a heart murmur: evaluation, assessment and dental considerations

Lessard, Eric; Glick, Michael; Ahmed, Sultan; Saric, Muhamed
BACKGROUND: Heart murmurs, a common finding in dental patients, are of major concern to dental professionals because certain dental procedures occasionally can induce severe cardiovascular complications. Murmurs may indicate existing heart disease that is a risk factor for infective endocarditis following a dental procedure, as well as more severe heart conditions such as congenital heart disease, atrial fibrillation or congestive heart failure. TYPES OF STUDIES REVIEWED: This review article is based on data published in peer-reviewed journals, including practice guidelines published by major dental and medical professional organizations. RESULTS: Echocardiography is the primary means of evaluating heart murmurs, and all dental professionals should become familiar with major aspects of an echocardiogram. Understanding the medical evaluation and assessment of a heart murmur fosters better communication with other health care professionals and results in improved patient care. CLINICAL IMPLICATIONS: Beyond the need to administer antibiotic prophylaxis, the dentist also needs to address the underlying causes of a patient's heart murmur. By providing dental care to such patients, oral health care providers become part of the patient's overall health care team
PMID: 15819349
ISSN: 0002-8177
CID: 102227

[Echocardiographic assessment of diagnosis and prognosis of biopsy-proven amyloid cardiomyopathy] [Case Report]

Sokol, Ivan; Vincelj, Josip; Saric, Muhamed
Amyloid cardiomyopathy is myocardial infiltrative disorder which mostly has been seen as the consequence of systemic amiloidosis. The diffuse global myocardial infiltration of nonfunctional amyloid displaces the contractile myocites giving rice to relaxation abnormality and diastolic dysfunction of restrictive or congestive type of both ventricles, but more frequently with right-sided congestion, while systolic left ventricular function deteriorates late in disease process. We report a patient with amyloid cardiomyopathy and nephrotic syndrome underlying primary amiloidosis. Our aim is to point out at echocardiographic assessment of diagnosis and prognosis of amyloid cardiomyopathy, which is proven by postmortal endomyocardial biopsy. The hallmark of echocardiographic diagnostics are the findings of the thickened ventricular and septal walls, small ventricular cavities, dilated atria with thickened interatrial septum and atrioventricular valves, and granular-sparkling and hyperrefractile myocardium. Doppler assessment diagnostically gives us the insight in restrictive physiology of both ventricles, and the inverse relation of the left ventricular thickness and voltage on the ECG is high specific. Echocardiographic evaluation of mean left ventricular thickness in amyloid cardiomyopathy is very important prognostic parameter. so that if it is > or =15 mm, median survival is 0.4 years, whereas in our patient with median thickness of 2.76 cm the survival was only three months. The advanced diastolic dysfunction of the left ventricle with an increased transmitral E/A ratio and deceleration time of < or =150 ms is strong predictor of cardiac death. In this case of restrictive transmitral flow E/A was 1.7 and DT 100 ms and they were ominous prognostic signs of survival
PMID: 16268073
ISSN: 0350-199x
CID: 102224