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Preoperative bisphosphonate treatment may adversely affect the outcome after shoulder arthroplasty
Mai, D H; Oh, C; Doany, M E; Rokito, A S; Kwon, Y W; Zuckerman, J D; Virk, M S
AIMS/OBJECTIVE:The aim of this study was to investigate the effects of preoperative bisphosphonate treatment on the intra- and postoperative outcomes of arthroplasty of the shoulder. The hypothesis was that previous bisphosphonate treatment would adversely affect both intra- and postoperative outcomes. PATIENTS AND METHODS/METHODS:group, there were 52 female and six male patients, with a mean age of 72.1 years (53 to 88). RESULTS:Previous treatment with bisphosphonates was positively associated with intraoperative complications (fracture; odds ratio (OR) 39.40, 95% confidence interval (CI) 2.42 to 6305.70) and one-year postoperative complications (OR 7.83, 95% CI 1.11 to 128.82), but did not achieve statistical significance for complications two years postoperatively (OR 3.45, 95% CI 0.65 to 25.28). The power was 63% for complications at one year. CONCLUSION/CONCLUSIONS:Patients who are treated with bisphosphonates during the three-year period before shoulder arthroplasty have a greater risk of intraoperative and one-year postoperative complications compared with those without this previous treatment.
PMID: 30700113
ISSN: 2049-4408
CID: 3626202
Subscapularis-Sparing Total Shoulder Arthroplasty: A Prospective, Double-Blinded, Randomized Clinical Trial
Kwon, Young W; Zuckerman, Joseph D
Although total shoulder arthroplasty (TSA) is generally associated with good to excellent outcomes in most patients, the integrity and function of the subscapularis tendon (SSC) is of paramount importance because SSC rupture after TSA can lead to inferior outcomes. Therefore, the efficacy of a SSC-sparing TSA procedure was evaluated through a prospective, double-blinded, randomized study. Patients with end-stage osteoarthritis of the shoulder were randomized into 2 groups. Group 1 patients were treated with TSA in which the prosthesis was inserted entirely through the rotator interval without violating the SSC tendon (SPARING). Group 2 patients were treated with TSA using the SSC tenotomy approach (STANDARD). Both the patients and the evaluators remained blinded to the surgical approach throughout the study. Outcome data collected included the visual analog scale score for pain and the American Shoulder and Elbow Surgeons outcome score. Complete 2-year outcome data were collected from 32 SPARING and 38 STANDARD patients at a mean follow-up of 31.1 and 33.4 months, respectively. The American Shoulder and Elbow Surgeons and visual analog scale scores improved significantly for both groups. Differences between groups did not reach statistical significance. Complication profiles were similar for the 2 groups, with 3 patients in the SPARING group and 2 patients in the STANDARD group requiring revision surgery during the study. At short-term follow-up, the outcome of TSA using the SSC-sparing surgical approach was similar to the outcome of TSA using the standard approach. Studies with longer follow-up are required to document the potential benefits of this surgical technique. [Orthopedics. 2019; 42(1):e61-e67.].
PMID: 30427055
ISSN: 1938-2367
CID: 3631152
Total Shoulder Arthroplasty Using Intraoperative 3D Navigation
Rosenthal, Yoav; Virk, Mandeep S; Zuckerman, Joseph D
Glenohumeral arthritis has become increasingly prevalent. For patients with glenohumeral arthritis and an intact rotator cuff, an anatomic total shoulder arthroplasty (TSA) has been shown to provide substantial pain relief with consistent, reproducible results. The primary indication is intractable pain that has not responded to nonoperative treatment, resulting in a substantial negative impact on the quality of life of the patient. Other indications for anatomic TSA include posttraumatic glenohumeral arthritis, inflammatory arthritis, and humeral head osteonecrosis. Contraindications include active infection, deltoid insufficiency, severe glenoid bone deficiency, and excessive glenohumeral posterior subluxation or laxity that cannot be surgically corrected. In order to provide the stability necessary to withstand the forces that impact the glenoid, the implant used in TSA should replicate the native anatomy of the individual patient by using a combination of implant modularity with different humeral neck angles and glenoid version augments, as well as dual eccentricity of the neck and head implant. The major steps in TSA include (1) preoperative planning, (2) patient positioning and setup, (3) surgical exposure, (4) accessing the glenohumeral joint, (5) preparation of the humerus, (6) exposure and preparation of the glenoid with component insertion, (7) humeral component insertion and trial reduction, (8) subscapularis reattachment and closure, and (9) postoperative immobilization and rehabilitation. The expected outcomes of TSA include improved quality of life (as indicated by improved outcome and patient satisfaction scores), shoulder active range of motion, and strength. In a large study examining outcomes of TSA in patients >55 years old, Patel et al.1 reported improved American Shoulder and Elbow Surgeons (48.3 ± 23.0), Constant (33.1 ± 16.7), and University of California Los Angeles (16.7 ± 6.3) shoulder scores, as well as improved active range of motion in active abduction (42° ± 41°), forward flexion (46° ± 40°), external rotation (33° ± 23°), and internal rotation (2.2° ± 1.8°) and decreased visual analog scale scores (-5.1 ± 2.9). Another study2 showed increased maximal weight improvement of 7.7 ± 4.0 lbs (3.5 ± 1.8 kg).
PMCID:6974318
PMID: 32051787
ISSN: 2160-2204
CID: 4304512
Implementation and early adaptation of patient-reported outcome measures into an electronic health record: A technical report
Gold, Heather Taffet; Karia, Raj J; Link, Alissa; Lebwohl, Rachel; Zuckerman, Joseph D; Errico, Thomas J; Slover, James D; Buckland, Aaron J; Mann, Devin M; Cantor, Michael N
We integrated and optimized patient-reported outcome measures into the electronic health record to provide quantitative, objective data regarding patients' health status, which is important for patient care, payer contracts, and research. With a multidisciplinary team from information technology, clinical informatics, population health, and physician champions, we used formal human-computer interaction techniques and user-centered design to integrate several technology platforms and computerized adaptive testing for the National Institutes of Health Patient-Reported Outcomes Measurement Information System. The patient-reported outcome measure system leverages software frequently used by health systems and provides data for research and clinical care via a mobile-responsive web application using Symfony, with REDCap for configuring assessments and de-identified data storage. The system incorporates Oracle databases and Epic flowsheets. Patients complete patient-reported outcome measures, with data viewable in MyChart and Epic Synopsis Reports. Researchers can access data portals. The highly usable, successful patient-reported outcome measures platform is acceptable to patients and clinicians and achieved 73 percent overall completion rates.
PMID: 30516095
ISSN: 1741-2811
CID: 3520672
Revision shoulder arthroplasty: Patient-reported outcomes vary according to the etiology of revision
Kim, Kelvin; Elbuluk, Ameer; Jia, Nathan; Osmani, Feroz; Levieddin, Joseph; Zuckerman, Joseph; Virk, Mandeep
Background/UNASSIGNED:The study evaluates patient-reported outcomes in revision shoulder arthroplasty (RevSA) according to etiology. Methods/UNASSIGNED:Twenty-three consecutive RevSA (minimum 2-year follow-up) were retrospectively reviewed. Patient-reported outcome (PRO) scores and range of motion were compared by the type of revision procedure and indication. Results/UNASSIGNED:EQ5D-QOL, VAS-pain, ASES, and forward elevation improved after RevSA. The infection group had least improvements. Revision to a reverse total shoulder arthroplasty (RTSA) demonstrated the most improvement in VAS-pain, forward elevation, and ASES. Conclusions/UNASSIGNED:Revision to RTSA significantly improved PRO scores compared to hemi- or total shoulder arthroplasty. RevSA for infection demonstrated the least improvement in outcomes.
PMCID:6126200
PMID: 30190633
ISSN: 0972-978x
CID: 3274812
Does a Learning Curve Exist for the Surgical Treatment of Proximal Humerus Fractures?
Egol, Kenneth A; Shulman, Brandon S; Belayneh, Rebekah; Karia, Raj J; Zuckerman, Joseph D
BACKGROUND:The complication rate of locked plating for proximal humerus fractures remains stubbornly high. The purpose of this study was to determine if a learning curve exists with the operative treatment of proximal humerus fractures. METHODS:We prospectively followed 161 consecutive patients with proximal humerus fractures treated by a single surgeon with locked plates from 2005 to 2016. Radiographic data, functional outcomes, and complications from the surgeon's first 81 patients were compared to the subsequent 80 patients. RESULTS:There was no statistical difference in the rates of complications (p = 0.29) or screw penetration (p = 0.19). There were no differences in DASH scores (p = 0.64 to 0.79) or tip-apex distance (p = 0.40). Head shaft angles were slightly smaller in patients treated earlier in the surgeon's career (p = 0.02). DISCUSSION/CONCLUSIONS:While surgeon experience is certainly a favorable quality, there does not appear to be a significant "learning curve" in the treatment of proximal humerus fractures.
PMID: 31513512
ISSN: 2328-5273
CID: 4088312
The Effect of Psychosensory Therapy on Short-term Outcomes of Total Joint Arthroplasty: A Randomized Controlled Trial
Cizmic, Zlatan; Edusei, Emmanuel; Anoushiravani, Afshin A; Zuckerman, Joseph; Ruden, Ronald; Schwarzkopf, Ran
Poor outcomes associated with increased perioperative opioid use have led investigators to seek alternative pain management modalities after total joint arthroplasty. Nonpharmacological approaches, such as electroceuticals, have shown promise. The purpose of this study was to evaluate the effects of "havening," a specific form of psychosensory therapy, on postoperative pain scores and narcotic consumption. In this prospective, randomized controlled trial, the authors compared 19 patients who underwent psychosensory therapy with 22 patients who served as the control group. Visual analog scale scores were collected preoperatively, every day during the hospitalization, and at approximately 1-month follow-up. Narcotic consumption during hospitalization was converted into daily morphine milligram equivalents and compared between the cohorts. In addition, postoperative complications, emergency department visits, and readmissions were compared between the cohorts. No difference in visual analog scale pain scores was reported between cohorts on postoperative day 1 (P=.229), at discharge (P=.434), or at 1-month follow-up (P=.256). Furthermore, there was no significant variance in mean daily morphine milligram equivalents (P=.221), length of stay (P=.313), postoperative complications (P=.255), 90-day readmissions (P=.915), and emergency department visits (P=.46) between the cohorts. This study showed that psychosensory therapy was not effective in reducing pain or narcotic consumption following total joint arthroplasty. Nonetheless, future studies assessing the role of psychosensory therapeutic interventions among patients after total joint arthroplasty are warranted to better understand the clinical implications of innovative therapies aimed at alleviating pain. [Orthopedics. 2018; 41(6):e848-e853.].
PMID: 30321440
ISSN: 1938-2367
CID: 4269692
The Academic Chair: Achieving Success in a Rapidly Evolving Health-Care Environment: AOA Critical Issues
Salazar, Dane H; Herndon, James H; Vail, Thomas P; Zuckerman, Joseph D; Gelberman, Richard H
There is a growing consensus that an accomplished curriculum vitae and prior achievement as an academician may not correlate with success as a chairperson of a contemporary academic orthopaedic department. As surgeons, formal professional education, research expertise, and clinical experience often are inadequate to foster the necessary skills and experience in executive leadership, change management, business administration, and strategy. The recruiting and hiring processes to fill academic leadership roles have been slow to adapt and recognize the skills that are necessary to be a successful chairperson. Recent research has identified emotional competency, resiliency, leadership, communication, results orientation, and personnel development as skills that correlate with success in academic leadership. Formal courses and training in executive leadership and business management may be helpful in enhancing knowledge and skills in these disciplines.
PMID: 30334894
ISSN: 1535-1386
CID: 3369802
Physical Therapy or Arthroscopic Surgery for Treatment of Meniscal Tears: Is Noninferiority Enough?
Jazrawi, Laith; Gold, Heather T; Zuckerman, Joseph D
PMID: 30285160
ISSN: 1538-3598
CID: 3329032
Osteonecrosis After Surgically Repaired Proximal Humerus Fractures Is a Predictor of Poor Outcomes
Belayneh, Rebekah; Lott, Ariana; Haglin, Jack; Konda, Sanjit; Zuckerman, Joseph D; Egol, Kenneth A
OBJECTIVES/OBJECTIVE:To determine the effect of osteonecrosis (ON) on the clinical and functional outcome after open reduction and internal fixation of proximal humerus fractures. DESIGN/METHODS:Prospective cohort study. SETTING/METHODS:Academic medical center. PATIENTS/METHODS:Over a 12-year period, patients were screened and identified on presentation to the emergency department or in the clinical office for inclusion in an institutional review board-approved registry. One hundred sixty-five patients with 166 proximal humerus fractures met inclusion criteria. Eight patients developed radiographic evidence of ON (4.8%). INTERVENTION/METHODS:Surgical repair of proximal humerus fractures. MAIN OUTCOME MEASURE/METHODS:Patients were divided into 2 cohorts; 1 cohort being those diagnosed with ON and the other cohort being those who were not. All patients were prospectively followed and assessed for clinical and functional outcomes at the latest follow-up visit (mean = 22.9 months) using the Disabilities of Arm, Shoulder and Hand survey along with ranges of motion of the injured extremity. RESULTS:Average postoperative forward elevation for patients with ON was worse than those without ON (P = 0.002). Additionally, there was a significant difference in Disabilities of Arm, Shoulder and Hand scores at the latest follow-up between the 2 groups (P = 0.026). There was no difference in external rotation or mean length of follow-up between the 2 groups (P > 0.05). CONCLUSIONS:This study demonstrates the negative effects of ON after open reduction and internal fixation of proximal humerus fractures. Those who develop ON have poorer functional and clinical outcomes as compared with patients without ON. Consequently, the development of ON can be used as a predictor of poor outcomes. LEVEL OF EVIDENCE/METHODS:Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
PMID: 30247282
ISSN: 1531-2291
CID: 3313982